Abstract:
:The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained were analyzed with regard to their protein composition and their genetic variability (qualitative and quantitative variants). Eighty to ninety percent of the H-S binding proteins were unique to this class of proteins. This class was rich in organ-specific proteins. Compared to the nonbinding proteins the portion of basic proteins was only slightly increased, suggesting that most of the H-S binding proteins interact specifically with heparin. The frequency of qualitative protein variants revealed that H-S binding proteins are more conservative than H-S nonbinding proteins. The quantitative genetic variability was higher in liver than in brain. Quantitative protein variants occurred more frequently than qualitative variants.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Jungblut P,Klose Jdoi
10.1007/BF00554529subject
Has Abstractpub_date
1986-12-01 00:00:00pages
925-39issue
11-12eissn
0006-2928issn
1573-4927journal_volume
24pub_type
杂志文章abstract::Larval serum protein-1 (LSP-1) and LSP-2 are the major proteins of Drosophila larval serum. The amount of LSP-1 synthesized is strictly proportional to the number of LSP-1 genes present within the range 1-10. The normal number in female flies is 6. Flies with extreme amounts of LSP-1 were, by our criteria, as fit as t...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499473
更新日期:1984-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
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journal_title:Biochemical genetics
pub_type: 杂志文章
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journal_title:Biochemical genetics
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499476
更新日期:1984-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00483996
更新日期:1981-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
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更新日期:1992-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484508
更新日期:1977-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484624
更新日期:1981-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484591
更新日期:1980-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00569326
更新日期:1992-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554726
更新日期:1995-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502790
更新日期:1986-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1015109321773
更新日期:2002-04-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/b:bigi.0000039807.50393.30
更新日期:2004-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00
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pub_type: 杂志文章
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502136
更新日期:1979-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-04-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9025-2
更新日期:2006-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00483751
更新日期:1978-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554146
更新日期:1991-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484206
更新日期:1978-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02395389
更新日期:1983-02-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426870
更新日期:1991-12-01 00:00:00
abstract::Patterns of lactate dehydrogenase (LDH) isozymes of tissues from various mouse strains were examined. An interstrain polymorphism for LDH isozymes of liver was established. One phenotype (CBA/Lac and AKR/J mice) yielded a five-banded LDH pattern, another phenotype (DBA/1J, DBA/2J, C57BL/6J and C3H/He) showed a three-b...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00500133
更新日期:1980-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10528-006-9035-0
更新日期:2006-10-01 00:00:00