Abstract:
:The interspecies homology of dace supernatant (A2,AB,B2) and mitochondrial (C2) malate dehydrogenase isozymes has been established through cell fractionation and tissue distribution studies. Isolated supernatant malate dehydrogenase (s-MDH) isozymes show significant differences in Michaelis constants for oxaloacetate and in pH optima. Shifts in s-MDH isozyme pH optima with temperature may result in immediate compensation for increase in ectotherm body pH with decrease in temperature, but duplicate s-MDH isozymes are probably maintained through selection for tissue specific regulation of metabolism.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Starzyk RM,Merritt RBdoi
10.1007/BF00484591subject
Has Abstractpub_date
1980-08-01 00:00:00pages
755-64issue
7-8eissn
0006-2928issn
1573-4927journal_volume
18pub_type
杂志文章abstract::In this study, we identified porcine single nucleotide polymorphisms (SNPs) by aligning eight sequences generated with two approaches: amplification of 665 intronic regions using one sample from each of eight breeds, including three East Asian pigs, and amplification of 289 3'-UTR regions using two samples from each o...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-011-9486-9
更新日期:2012-06-01 00:00:00
abstract::In order to clarify the genetic linkage groups of the Japanese brown frog Rana japonica, and compare them with those of other vertebrates, the inheritance of 10 enzyme and blood protein loci was examined in 267 offspring derived from 18 crosses using 10 males heterozygous at these loci. Most of the segregation tests e...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554413
更新日期:1996-10-01 00:00:00
abstract::The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484391
更新日期:1980-06-01 00:00:00
abstract::Propionyl-CoA carboxylase (PCC) is involved in the catabolism of branched chain amino acids, odd-numbered fatty acids, cholesterol, and other metabolites. PCC consists of two subunits, α and β, encoded by the PCCA and PCCB genes, respectively. Mutations in the PCCA or PCCB subunit gene may lead to propionic acidemia. ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9657-6
更新日期:2014-10-01 00:00:00
abstract::Two complementing loci in different linkage groups of the basidiomycete Ustilago violacea are involved in urease activity: a structural one (ure-1) and a second inferred to involve a permease (ure-2) locus. Two types of complementing mutations occur in the structural locus: null activity (ure-la) and obviously reduced...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484568
更新日期:1981-12-01 00:00:00
abstract::To investigate the sex differences of crossing-over in Rana japonica, the recombination frequencies between two linked loci, LDH-B and MPI, were examined in offspring obtained from 29 matings involving either females or males heterozygous at both loci. No recombinants were found among 303 offspring bred from 6 heteroz...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426898
更新日期:1994-10-01 00:00:00
abstract::In vitro DNA:DNA hybridizations and hydroxyapatite thermal-elution chromatography were employed to identify the diploid Triticum species ancestral to the B genome of T. turgidum. Unique and repeated sequences from the various Triticum species were separated by hybridization and thermal elution on hydroxyapatite. Uniqu...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502977
更新日期:1986-02-01 00:00:00
abstract::A novel cDNA fragment was identified from a human fetal brain cDNA library by using the coding sequence of human BRI3 gene (Accession No. NM015379) as bait in a yeast two-hybrid screening. Then by 5'-RACE (rapid amplification of cDNA end) and electronic hybridization, we obtained a 1.9 kb contig which consists of a no...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1013807518791
更新日期:2001-12-01 00:00:00
abstract::Seasonal changes in genetic diversity of Meriones meridianus and Dipus sagitta populations in the Ningxia Hui Autonomous Region were monitored using inter-simple sequence repeats. There were 45 discernible DNA fragments isolated from 33 samples of M. meridianus, and 25 from 40 samples of D. sagitta. The differences in...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-011-9480-2
更新日期:2012-06-01 00:00:00
abstract::The ribosomal RNA cistrons of three species of trout: Salvelinus namaycush (lake trout), Salvelinus fontinalis (brook trout), and Salmo gairdneri (rainbow trout) were examined by Southern blot analysis of genomic DNA. The repeat length of the cistron of S. namaycush is 26 kb. A repeat-length polymorphism was observed ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499943
更新日期:1985-12-01 00:00:00
abstract::The aldox-2 locus in Drosophila melanogaster has been shown to affect differentially three molybdoenzymes, aldehyde oxidase, pyridoxal oxidase, and xanthine dehydrogenase. These effects are most obvious at times surrounding the pupal-adult boundary, when the normal organism accumulates large amounts of these enzymes i...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499002
更新日期:1986-10-01 00:00:00
abstract::The nucleoside monophosphate kinases, adenylate kinase (AK), guanylate kinase (GUK), and uridine monophosphate kinase (UMPK), were studied electrophoretically and quantitatively in density gradient fractions of human red cells from normal adults which contain red cells of differing mean age. The enzymes were found to ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484542
更新日期:1978-12-01 00:00:00
abstract::This work examines the molecular evolution of a brain-expressed X-linked gene family in the mammalian genomes of human, chimp, macaque, mouse, rat, dog, and cow. The gene structures are well conserved across family members and among the mammals in that all five members have three exons with the first two exons untrans...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9148-8
更新日期:2008-06-01 00:00:00
abstract::Ade-H and ade-I are two auxotrophic mutants of Chinese hamster ovary (CHO-K1) cells which specifically require adenine as the purine source to grow. The enzymatic defects of these mutants were examined in cell-free extracts. It was found that ade-H did not have any detectable adenylosuccinate synthetase activity and a...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484561
更新日期:1977-02-01 00:00:00
abstract::Preeclampsia leads to maternal and perinatal morbidity and mortality. The literature in English was reviewed to summarize recent advances in understanding the global gene expression changes in the pathogenesis of preeclampsia. We identified at least eight consistently enriched categories, relating to pregnancy mainten...
journal_title:Biochemical genetics
pub_type: 杂志文章,评审
doi:10.1007/s10528-015-9684-y
更新日期:2015-10-01 00:00:00
abstract::Single nucleotide polymorphisms (SNP) in the resistin gene (RETN) are linked to obesity and resistin levels in various populations. However, results have been inconsistent. This study aimed to investigate association between polymorphisms in the resistin gene with obesity in a homogenous Malaysian Malay population. Th...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-015-9678-9
更新日期:2015-06-01 00:00:00
abstract::Scirpophaga incertulas, commonly referred to as yellow stem borer, is a predominant pest of rice causing serious losses in its yield. Genetic variation among populations of Scirpophaga incertulas collected from 28 hotspot locations in India was examined using the randomly amplified polymorphic DNA-polymerase chain rea...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1002797219182
更新日期:2001-02-01 00:00:00
abstract::Alcohol dehydrogenase from Drosophila funebris and D. immigrans is evident at all developmental stages. The highest activity level appears in third-instar larvae and declines to a lower level at all later stages of development. Both species are monomorphic. The enzyme is a dimer consisting of two identical subunits wi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499474
更新日期:1984-10-01 00:00:00
abstract::Three distinct malathion carboxylesterase (MCE) phenotypes have been identified among strains of Lucilia cuprina. The high-activity phenotype shows 1.6- and 33-fold more MCE specific activity than the intermediate- and low-activity phenotypes, respectively. Flies with high MCE activity are 1000-fold more resistant to ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00566064
更新日期:1994-12-01 00:00:00
abstract::Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-019-09929-x
更新日期:2019-10-01 00:00:00
abstract::Electrophoretic variation is described for malic enzyme (ME) for the first time in brook trout (Salvelinus fontinalis). Since the quaternary structure of ME was not clear from examination of banding patterns in brook trout alone, ME phenotypes in rainbow trout (Salmo gairdneri)X brook trout hybrids as wel as in esoci...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502121
更新日期:1979-08-01 00:00:00
abstract::Horizontal starch gel electrophoresis revealed five hemoglobin phenotypes in natural populations of the encinal mouse, Peromyscus pectoralis, from northeastern Mexico. Populations of the encinal mouse from Texas, Oklahoma, and northwestern and north central Mexico were monomorphic for multiple-band phenotypes. Analysi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484880
更新日期:1976-02-01 00:00:00
abstract::Genetic variations affecting the course of depressive symptoms in patients with coronary artery disease (CAD) have not yet been well studied. Therefore, we set out to investigate whether distinct haplotypes of the two insertion/deletion polymorphisms in the serotonin-transporter-linked polymorphic region (5-HTTLPR) an...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09967-w
更新日期:2020-08-01 00:00:00
abstract::Eukaryotic translation initiation factors (eIFs) have been shown to be critical in the initiation of protein synthesis. Here, we report the cloning and characterization of a novel gene, LceIF1, from a potentially interesting forage grass, Leymus chinensis (Trin.). The expression results show that LceIF1 is expressed i...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-012-9546-9
更新日期:2013-02-01 00:00:00
abstract::A null mutation at the phosphoglucomutase locus (Pgm-1) was discovered by electrophoretic analysis of the inbred mouse strain C57BL/6J. The null allele (Pgm-1n) was shown to segregate as a Mendelian unit alternative to the Pgm-1a and Pgm-1b alleles. Mice expressing the Pgm-1n allele, either in the heterozygous or homo...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484629
更新日期:1981-06-01 00:00:00
abstract::Inheritance of gliadin components unique to three different varieties of common wheat (Triticum aestivum L.) was studied in F1 and F2 seeds of intervarietal crosses using protein patterns obtained by polyacrylamide gel electrophoresis in aluminum lactate buffer (pH 3.2). The patterns of F1 seeds of the crosses Cheyenn...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484739
更新日期:1978-08-01 00:00:00
abstract::To determine the genetic structure and variation of Van cats and some other cats, seven enzyme loci were examined using horizontal starch gel electrophoresis. ME bands were observed for the first time in cats. For the enzyme loci CA ( 1 ), SOD, GPI, and GOT, neither the individual Van cats nor the specimens of other c...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-011-9426-8
更新日期:2011-08-01 00:00:00
abstract::DNA polymorphisms in the psi beta 1-beta-globin gene region in nine Asian macaques (Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, and M. assamensis) were examined using several restriction endonucleasese and the human psi beta 1, delta IVS2, and beta IVS2 ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02401811
更新日期:1991-04-01 00:00:00
abstract::A partial paired gene of Drosophila willistoni containing the paired box and extended homeo box was amplified by PCR and the nucleotide sequence of 1141 bp was determined. Comparison of the paired genes in D. willistoni and D. melanogaster showed that the proportions of identical nucleotide sites in the coding region ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00570122
更新日期:1996-12-01 00:00:00
abstract::Apodemus peninsulae is a field mouse that inhabits the broad-leafed forests of temperate Eurasia. We examined the mitochondrial cytochrome b gene in 57 in dividuals of A. peninsulae from northeastern Asia, including Siberia, Primorye, Magadan region, Sakhalin, Hokkaido, and the Korean Peninsula. The genealogy of the m...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1015841424598
更新日期:2002-06-01 00:00:00