Abstract:
:Horizontal starch gel electrophoresis revealed five hemoglobin phenotypes in natural populations of the encinal mouse, Peromyscus pectoralis, from northeastern Mexico. Populations of the encinal mouse from Texas, Oklahoma, and northwestern and north central Mexico were monomorphic for multiple-band phenotypes. Analysis of the hemoglobin polymorphism indicates that two loci control this variation.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Kilpatrick CW,Zimmerman EGdoi
10.1007/BF00484880subject
Has Abstractpub_date
1976-02-01 00:00:00pages
137-43issue
1-2eissn
0006-2928issn
1573-4927journal_volume
14pub_type
杂志文章abstract::Chromosomal locations of 10 isozyme loci in rice (Oryza sativa L.) were determined through trisomic analysis. All 10 genes produced altered allozyme banding patterns in specific F1 trisomics. This served as the primary source of evidence for chromosome locations of Est-5, Icd-1, Acp-1, and Pgd-1. The locations of Amp-...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00561468
更新日期:1988-04-01 00:00:00
abstract::Single-chain variable fragment (scFv) is one of the most common antibody forms. This report describes the expression of the scFv gene as a soluble protein in Origami DE3 cytoplasm. The purified scFv recognized the epidermal growth factor receptor (EGFRvIII) on the surface of MCF-7 cells. The scFv protein was purified ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-012-9506-4
更新日期:2012-08-01 00:00:00
abstract::DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-015-9707-8
更新日期:2016-04-01 00:00:00
abstract::A partial paired gene of Drosophila willistoni containing the paired box and extended homeo box was amplified by PCR and the nucleotide sequence of 1141 bp was determined. Comparison of the paired genes in D. willistoni and D. melanogaster showed that the proportions of identical nucleotide sites in the coding region ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00570122
更新日期:1996-12-01 00:00:00
abstract::Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, w...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485334
更新日期:1976-10-01 00:00:00
abstract::Mitochondrial DNA (mtDNA) from two breeds of cattle, viz., [Hariana (Bos indicus), Holstein (Bos taurus)] and Indian water buffalo (Bubalis bubalus), was analyzed using 13 restriction endonucleases which recognized an average of about 40 six-base sites. Polymorphism among cattle was detected with six of these enzymes....
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02401421
更新日期:1990-08-01 00:00:00
abstract::This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SNPs (rs4536, rs4545, rs3097, and rs3802230) and the K173R polymorphism...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9393-5
更新日期:2011-02-01 00:00:00
abstract::Preeclampsia leads to maternal and perinatal morbidity and mortality. The literature in English was reviewed to summarize recent advances in understanding the global gene expression changes in the pathogenesis of preeclampsia. We identified at least eight consistently enriched categories, relating to pregnancy mainten...
journal_title:Biochemical genetics
pub_type: 杂志文章,评审
doi:10.1007/s10528-015-9684-y
更新日期:2015-10-01 00:00:00
abstract::A new hemoglobin variant found in a mother and her child was characterized by column chromatography of the tryptic hydrolysate of the aminoethylated, glycinamidated beta-chain, followed by chymotryptic digestion of the abnormal beta T-9 peptide and amino acid analyses. It was shown to be alpha2beta2 73(E17)Asp replace...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485784
更新日期:1975-08-01 00:00:00
abstract::The Wood Stork (Mycteria americana) is a colonial wading bird of the tropical and lower subtropical zones. We assessed genetic structure within and among five stork colonies from the Brazilian Pantanal and compared our data with those from North American populations. Samples of 234 individuals were studied using prote...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1015109321773
更新日期:2002-04-01 00:00:00
abstract::Evidence is presented to show that the Sh locus specifies sucrose synthetase in the developing endosperm of maize. The sh/sh/sh endosperm possesses less than 10% sucrose synthetase activity as compared to the normal Sh/sh/sh endosperm. The residual enzyme activity in five independently derived mutant genotypes is attr...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485135
更新日期:1976-12-01 00:00:00
abstract::Three high-glucose-6-phosphate dehydrogenase (G6PD)-activity mutants (2512H, S44H, and 1FH) are characterized by two insertion sequences associated with the G6PD locus; one (Ins1; 3.5 kb long in 2512H and S44H and 2.9 kb long in 1FH) is present just 5' to exon I and consists of a KP' (the 32nd base of the KP was repla...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02396062
更新日期:1989-12-01 00:00:00
abstract::The present study intends to survey the genetic variability of an endangered semiferal Portuguese native pony breed, the Garrano. Thirteen microsatellite markers were examined in 277 animals born in 1998, belonging to eight subpopulations corresponding to eight northern Portuguese geographic regions. Mean heterozygosi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-005-6775-1
更新日期:2005-08-01 00:00:00
abstract::A significant challenge in epistasis detection is the huge amount of data, which leads to combinatorial explosion. This study focuses on a two-stage approach for detecting epistasis only among single nucleotide polymorphisms (SNPs) that show some marginal effect. We present this two-stage approach based on the fusion ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9656-7
更新日期:2014-10-01 00:00:00
abstract::The extent of naturally occurring variations of enzyme locus expression was determined for three tissues (liver, muscle, and eye) in two species of sunfish (Centrarchidae), the green sunfish (Lepomis cyanellus) and the redear sunfish (L. microlophus). The genetic basis for species differences in tissue enzyme specific...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499484
更新日期:1984-10-01 00:00:00
abstract::For a number of decades, the lesser white-fronted goose (Anser erythropus) has been almost-absent from the Fennoscandian fauna and has a current population size of only about 60 breeding pairs, with fewer than 10 pairs in Sweden. During the period 1981-1991 more than 200 young have been reintroduced in northern Sweden...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::In vitro DNA:DNA hybridizations and hydroxyapatite thermal-elution chromatography were employed to identify the diploid Triticum species ancestral to the B genome of T. turgidum. Unique and repeated sequences from the various Triticum species were separated by hybridization and thermal elution on hydroxyapatite. Uniqu...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502977
更新日期:1986-02-01 00:00:00
abstract::The variable numbers of tandem repeats (VNTR) locus D1S80, located on chromosome 1 (1p35-36), has a repeat unit 16 bp in length, and different numbers of these repeat units have been observed for populations of different origins and ethnicity. We used a molecular identification method based on capillary electrophoresi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9250-6
更新日期:2009-08-01 00:00:00
abstract::In fission yeast (Schizosaccharomyces pombe) the homologue of the mammalian SUMO-1 ubiquitin-like modifier is encoded by the pmt3 gene. A two-hybrid screen using the telomere-binding protein Taz1p as bait identified Pmt3p as an interacting factor. In vitro experiments using purified components of the fission yeast Pmt...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-005-1503-4
更新日期:2005-04-01 00:00:00
abstract::Soluble starch synthase and branching enzyme were purified from 18-day-old cotyledons of the smooth-seeded pea cultivar Alaska (RR) and wrinkled-seeded pea cultivar Progress #9 (rr) by DEAE-cellulose chromatography. Two coeluting peaks of primed and citrate-stimulated starch synthase activity and a major and minor pea...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484061
更新日期:1982-10-01 00:00:00
abstract::Genetic variations affecting the course of depressive symptoms in patients with coronary artery disease (CAD) have not yet been well studied. Therefore, we set out to investigate whether distinct haplotypes of the two insertion/deletion polymorphisms in the serotonin-transporter-linked polymorphic region (5-HTTLPR) an...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09967-w
更新日期:2020-08-01 00:00:00
abstract::Maternal embryo leucine zipper kinase (MELK) has a higher expression level in a variety of cancers and involved in progression of colorectal cancer. The MELK expression levels in colorectal cancer tissues and cells were detected by RT-qPCR. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and transwe...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09974-x
更新日期:2020-10-01 00:00:00
abstract::Human cells irradiated with UV light synthesize lower molecular weight DNA than unirradiated cells. This reduction in molecular weight is greater in xeroderma pigmentosum (XP) cells than in normal cells. The molecular weight of DNA is further reduced by the addition of caffeine to XP cells. By several hours after irra...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00504267
更新日期:1981-04-01 00:00:00
abstract::Melanoma formation in Xiphophorus hybrids is mediated by a growth factor receptor tyrosine kinase oncogene encoded by the Tu locus. In the wild-type parental fish no tumors occur due to the activity of a locus that regulates the activity of the melanoma oncogene. Molecular identification of this regulatory locus (R) r...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426867
更新日期:1991-12-01 00:00:00
abstract::The nucleoside monophosphate kinases, adenylate kinase (AK), guanylate kinase (GUK), and uridine monophosphate kinase (UMPK), were studied electrophoretically and quantitatively in density gradient fractions of human red cells from normal adults which contain red cells of differing mean age. The enzymes were found to ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484542
更新日期:1978-12-01 00:00:00
abstract::Liver homogenate-supernatants from most Japanese exhibit an "atypical" pH optimum for ethanol oxidation at pH 8.8 instead of 10.5, the "typical" pH-activity optimum. It has been proposed that atypical livers contain alcohol dehydrogenase isozymes with beta 2 subunits while typical livers contain isozymes with beta 1 s...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499296
更新日期:1984-02-01 00:00:00
abstract::Sequence divergence of mitochondrial COII was analyzed in 50 specimens belonging to five subspecies of Polyura eudamippus (Lepidoptera: Nymphalidae) collected from southern China. There were nine haplotypes in the 405 bp of partial COII sequence. Distribution of the five subspecies was primarily consistent with the sp...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9035-0
更新日期:2006-10-01 00:00:00
abstract::Linkage data for the sex-linked malic enzyme (Me) and hexokinase-1 (Hk-1) loci in the flour beetle, Tribolium confusum, were obtained from a three-point experiment involving the red locus. The order of the three loci was determined to be red--Hk-1-Me, with map distances of 12.4 +/- 1.8 for red to Hk-1 and 7.0 +/- 1.3 ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498914
更新日期:1983-08-01 00:00:00
abstract::In flowers of Dianthus caryophyllus (carnation), the gene I is concerned with a discrete step in flavonoid biosynthesis, Genotypes with recessive (ii) alleles produce yellow flowers, which contain the chalcone isosalipurposide (naringenin-chalcone-2'-glucoside) as the major petal pigment, but in genotypes with wild-ty...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484399
更新日期:1980-06-01 00:00:00
abstract::Two types of alleles exist in the human alcohol dehydrogenase-2 (ADH2) locus. The usual ADH12 allele is common in Caucasians, while the atypical ADH22 allele is predominant in Orientals. The ADH22 produces the beta 2 subunit, which is catalytically far more active than the beta 1 subunit produced by the ADH12 gene. Th...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02399419
更新日期:1988-08-01 00:00:00