Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences in Xiphophorus.

abstract：:High levels of nuclease activities were identified in filtrates of Aspergillus cultures after growth in low-but not in high-phosphate media. Deoxyribonuclease activities, characterized extensively by column chromatography, showed a coincident single peak for ss- and ds-DNase which was distinct from the peak for RNase....

journal_title：Biochemical genetics

authors： Käfer E,Tittler A,Fraser MJ

更新日期：1989-04-01 00:00:00

abstract：:The frequency distributions of apolipoprotein C alleles in native Asian sheep (Bengal, Kagi, Lampuchhre, Vietnamese, Myanmar, Baruwal, Bhyanglung, Khalkhas, and Kuwait) were determined using a one-dimensional polyacrylamide gel isoelectric-focusing immunoblotting technique. Among these Asian sheep, the genetic locus c...

journal_title：Biochemical genetics

authors： Tsunoda K,Watanabe S,Sato J,Sato K

更新日期：2002-12-01 00:00:00

abstract：:A new polymorphism, Pc, has been identified in human saliva. Two proteins, Pc 1 and Pc 2, are determined by alleles Pc1 and Pc2, respectively, which show autosomal codominant inheritance. No null phenotype has been encountered in 225 randomly collected salivas. The frequencies of the two alleles differ in the Black an...

journal_title：Biochemical genetics

authors： Karn RC,Goodman PA,Yu PL

更新日期：1985-02-01 00:00:00

abstract：:Isoenzyme electrophoresis was used as a method to determine genetic diversity in various M. esculenta cultivars collected in the Southwestern (SW) and Northwestern (NW) regions of the State of Parana, in the South region of Brazil, and in cultivars produced at the Agronomic Institute of Campinas (IAC), São Paulo State...

journal_title：Biochemical genetics

authors： Resende AG,Vidigal Filho P,Machado MF

更新日期：2000-08-01 00:00:00

abstract：:Using megagametophyte (maternal haploid) and embryo (diploid) tissues of incense-cedar seeds, the expression of one of three malate dehydrogenase (MDH) loci was found to be influenced by a second, unlinked, modifier locus. Whereas alleles of the affected structural locus are codominant, the modifier alleles show domin...

journal_title：Biochemical genetics

authors： Harry DE

更新日期：1983-06-01 00:00:00

abstract：:In this study, we identified porcine single nucleotide polymorphisms (SNPs) by aligning eight sequences generated with two approaches: amplification of 665 intronic regions using one sample from each of eight breeds, including three East Asian pigs, and amplification of 289 3'-UTR regions using two samples from each o...

journal_title：Biochemical genetics

authors： Matsumoto T,Okumura N,Uenishi H,Hayashi T,Hamasima N,Awata T

更新日期：2012-06-01 00:00:00

abstract：:The enzyme UDPglucose:flavonol 3-O-glucosyltransferase is shown to be under the coordinate control of three genes involved in anthocyanin biosynthesis in the aleurone of maize: C, R, and BZ. Of the three, BZ appears to be the structural gene. Data presented here (dosage comparisons, induction in the mutant c-p, and ef...

journal_title：Biochemical genetics

authors： Dooner HK,Nelson OE

更新日期：1977-06-01 00:00:00

abstract：:The cryptic plasmid pGY1, which is harbored by a clinical isolate of Salmonella enterica serovar Paratyphi A, was identified in a 9-year-old girl with paratyphoid fever in 2005, and its DNA sequence was determined. It is 3592 bp in length and had a G+C content of 43.3%. Three ORFs were predicted that share low similar...

journal_title：Biochemical genetics

authors： Huang H,Li J,Yang XL,Wang YG,Wang YP,Tao JS,Huang YZ,Zhang XL

更新日期：2009-04-01 00:00:00

abstract：:Ade-H and ade-I are two auxotrophic mutants of Chinese hamster ovary (CHO-K1) cells which specifically require adenine as the purine source to grow. The enzymatic defects of these mutants were examined in cell-free extracts. It was found that ade-H did not have any detectable adenylosuccinate synthetase activity and a...

journal_title：Biochemical genetics

authors： Tu AS,Patterson D

更新日期：1977-02-01 00:00:00

abstract：:A slow-migrating beta-esterase (S-esterase) is described which has been detected in Drosophila montana, Drosophila imeretensis, and some stocks of Drosophila virilis when mixtures of alpha- and beta-naphthyl acetate are used as substrates in histochemical reactions after electrophoresis. Sexual dimorphism for S-estera...

journal_title：Biochemical genetics

authors： Korochkin LI,Belyaeva ES,Matveeva NM,Kuzin BA,Serov OL

更新日期：1976-02-01 00:00:00

abstract：:Liver homogenate-supernatants from most Japanese exhibit an "atypical" pH optimum for ethanol oxidation at pH 8.8 instead of 10.5, the "typical" pH-activity optimum. It has been proposed that atypical livers contain alcohol dehydrogenase isozymes with beta 2 subunits while typical livers contain isozymes with beta 1 s...

journal_title：Biochemical genetics

authors： Yin SJ,Bosron WF,Li TK,Ohnishi K,Okuda K,Ishii H,Tsuchiya M

更新日期：1984-02-01 00:00:00

abstract：:Patterns of lactate dehydrogenase (LDH) isozymes of tissues from various mouse strains were examined. An interstrain polymorphism for LDH isozymes of liver was established. One phenotype (CBA/Lac and AKR/J mice) yielded a five-banded LDH pattern, another phenotype (DBA/1J, DBA/2J, C57BL/6J and C3H/He) showed a three-b...

journal_title：Biochemical genetics

authors： Khlebodarova TM,Serov OL

更新日期：1980-10-01 00:00:00

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:Two alleles are encoded at the malate dehydrogenase locus in largemouth bass, Micropterus salmoides. Populations in the extreme northern areas of the range of this fish are fixed or nearly fixed for the B1 allele, whereas populations in Florida are fixed for the alternative allele, B2. The MDH-B1B1 and MDH-B2B2 alleli...

journal_title：Biochemical genetics

authors： Hines SA,Philipp DP,Childers WF,Whitt GS

更新日期：1983-12-01 00:00:00

abstract：:In corn seedlings (Zea mays L.) homozygous for the mutation gl5, the surface waxes are characteristically altered. In this mutant the main wax constituents (83.5%) are aldehydes while in the normal waxes alcohols predominate (62.7%). Moreover, in the normal waxes aldehydes and alcohols are made up mainly of the C32 te...

journal_title：Biochemical genetics

authors： Bianchi G,Avato P,Salamini F

更新日期：1978-10-01 00:00:00

abstract：:The stem-loop potential of a nucleic acid segment (expressed as a FONS value), decomposes into base composition-dependent and base order-dependent components. The latter, expressed as a FORS-D value, is derived by subtracting the value of the base composition-dependent component (FORS-M) from the FONS value. FORS-D an...

journal_title：Biochemical genetics

authors： Zhang CY,Wei JF,Wu JS,Xu WR,Sun X,He SH

更新日期：2008-02-01 00:00:00

abstract：:Larval serum protein-1 (LSP-1) and LSP-2 are the major proteins of Drosophila larval serum. The amount of LSP-1 synthesized is strictly proportional to the number of LSP-1 genes present within the range 1-10. The normal number in female flies is 6. Flies with extreme amounts of LSP-1 were, by our criteria, as fit as t...

journal_title：Biochemical genetics

authors： Roberts DB,Blackwell SA,Loughlin SA

更新日期：1984-10-01 00:00:00

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:Myogenic differentiation 1 (MyoD1) genes belong to the MyoD gene family and play key roles in growth and muscle development. This study was designed to investigate the effects of variants in the MyoD1 gene on duck growth and carcass traits. Three duck populations (Cherry Valley, Jingjiang, and Muscovy) were sampled, t...

journal_title：Biochemical genetics

authors： Wu Y,Pi JS,Pan AL,Pu YJ,Du JP,Shen J,Liang ZH,Zhang JR

更新日期：2012-12-01 00:00:00

abstract：:The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained wer...

journal_title：Biochemical genetics

authors： Jungblut P,Klose J

更新日期：1986-12-01 00:00:00

abstract：:Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of haplotype A in six bre...

journal_title：Biochemical genetics

authors： Zhang B,Chen H,Hua L,Zhang C,Kang X,Wang X,Pan C,Lan X,Lei C

更新日期：2008-06-01 00:00:00

abstract：:Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...

journal_title：Biochemical genetics

authors： Mashayekhi F,Shafiee G,Kazemi M,Dolati P

更新日期：2010-08-01 00:00:00

abstract：:Because alternative RNA splicing regulation in the testis is prevalent, we explored testes of Sprague-Dawley rats for existence of alternatively spliced colony-stimulating factor 1 receptor (CSF-1R) mRNA. Using RT-PCR and sequencing, we identified a variant of CSF-1R mRNA that was 284 bp shorter than the full-length C...

journal_title：Biochemical genetics

authors： Su H,Wang Y,Söder O,Hou M

更新日期：2014-06-01 00:00:00

abstract：:Genetics and linkage analysis of 6-phosphogluconate dehydrogenase (6-PGD) and malate dehydrogenase (MDH) have been investigated in Anopheles stephensi. Both these markers were found to be autosomal and linked and have been assigned to linkage group III. Two mutant markers, Black larva (Bl) and golden-yellow larva (gy)...

journal_title：Biochemical genetics

authors： Adak T,Subbarao SK,Sharma VP,Rao SR

更新日期：1992-10-01 00:00:00

abstract：:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) exhibit genetic polymorphism and tissue specificity. ADH and ALDH isozyme phenotypes from 39 surgical Chinese lung specimens were identified by agarose isoelectric focusing. The identity of the lung beta-ADHs was further demonstrated by their characteristic...

journal_title：Biochemical genetics

authors： Yin SJ,Liao CS,Chen CM,Fan FT,Lee SC

更新日期：1992-04-01 00:00:00

abstract：:Non-alcoholic fatty liver disease is one of the main causes of chronic liver disease and therefore is currently considered a major public health problem. Sirtuin 1 (SIRT1) is an NAD-dependent deacetylase enzyme that contributes in the regulation of metabolic processes and protects against lipid accumulation in hepatoc...

journal_title：Biochemical genetics

authors： Borji M,Nourbakhsh M,Shafiee SM,Owji AA,Abdolvahabi Z,Hesari Z,Ilbeigi D,Seiri P,Yousefi Z

更新日期：2019-08-01 00:00:00

abstract：:The concentration of D-beta-aminoisobutyric acid (D-BAIB) in the liver and kidney was twice as high and dropped more slowly in the female mouse than in the male after an intraperitoneal injection of thymine. The concentration of beta-alanine, formed from uracil by the same enzyme system catalyzing formation of D-BAIB ...

journal_title：Biochemical genetics

authors： Miyake M,Kanazawa A,Kakimoto Y

更新日期：1979-08-01 00:00:00

abstract：:The antigenic properties of a number of chromatographically purified primate hemoglobins were compared to those of normal human hemoglobin using a sensitive radioimmunochemical procedure. The degree of inhibition of the antigen-antibody reaction with heterologous hemoglobins appeared to be related to the structural si...

journal_title：Biochemical genetics

authors： Garver FA,Talmage DW

更新日期：1975-12-01 00:00:00

abstract：:Maternal embryo leucine zipper kinase (MELK) has a higher expression level in a variety of cancers and involved in progression of colorectal cancer. The MELK expression levels in colorectal cancer tissues and cells were detected by RT-qPCR. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and transwe...

journal_title：Biochemical genetics

authors： Liu G,Zhan W,Guo W,Hu F,Qin J,Li R,Liao X

更新日期：2020-10-01 00:00:00

abstract：:A new variant of alcohol dehydrogenase (ADH 7lk) was found in a laboratory stock of Drosophila melanogaster. ADH in this stock had the same electrophoretic mobility as the F variant both on acrylamide and on agar. Activity levels were similar to the levels in F flies at temperature between 15 and 25 C. But while ADH F...

journal_title：Biochemical genetics

authors： Thörig EW,Schoone AA,Scharloo W

更新日期：1975-10-01 00:00:00