Abstract:
:To investigate the sex differences of crossing-over in Rana japonica, the recombination frequencies between two linked loci, LDH-B and MPI, were examined in offspring obtained from 29 matings involving either females or males heterozygous at both loci. No recombinants were found among 303 offspring bred from 6 heterozygous males, whereas 160 were parental and 138 were recombinants among 298 offspring bred from 9 heterozygous females. The recombination frequency was 46.3%. These results show that the sex difference when two loci were recombined was marked and significant in Rana japonica.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Sumida M,Nishioka Mdoi
10.1007/BF02426898subject
Has Abstractpub_date
1994-10-01 00:00:00pages
361-9issue
9-10eissn
0006-2928issn
1573-4927journal_volume
32pub_type
杂志文章abstract::A genetic locus controlling the electrophoretic mobility of a methylglyoxal dehydrogenase (EC 1.2.1.23) in the rat is described. The locus, designated Mgd1, is expressed in liver and kidney. Inbred rat strains have fixed either allele Mgd1a or allele Mgd1b. Codominant expression is observed in heterozygotes, providing...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554618
更新日期:1994-06-01 00:00:00
abstract::Imprinted genes are characterized by monoallelic expression that is dependent on parental origin. Comparative analysis of imprinted genes between species is a powerful tool for understanding the biological significance of genomic imprinting. The slc38a4 gene encodes a neutral amino acid transporter and is identified a...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-018-9866-5
更新日期:2018-12-01 00:00:00
abstract::This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SNPs (rs4536, rs4545, rs3097, and rs3802230) and the K173R polymorphism...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9393-5
更新日期:2011-02-01 00:00:00
abstract::The segregation of human lysosomal arylsulfatase A (ARS-A) has been evaluated in 50 primary hybrid clones derived from four separate fusions involving WBCs from two unrelated individuals and three hamster cell lines. ARS-A was expressed in the hybrids as a dimeric molecule of very similar or identical subunits. The ex...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00504344
更新日期:1979-12-01 00:00:00
abstract::Nineteen inbred strains of the laboratory rat (Rattus norvegicus) were investigated for genetic differences by starch and agarose gel electrophoretic techniques. For six out of 21 loci, interstrain differences were observed: Tf, 6PGD, Es-1, Es-4, Es-5, and Svp. The variants are briefly described and the allelic distri...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484206
更新日期:1978-06-01 00:00:00
abstract::Upland rice landraces from different villages of Mizoram, Northeast India were analyzed for seed morphology, amylose content, aromatic characteristic, seed storage protein profiling and genetic diversity. Results revealed variation in grain length, width, weight and shape. Protein profiling showed polypeptide bands ra...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-018-09901-1
更新日期:2019-06-01 00:00:00
abstract::Basal activity of submaxillary gland (SMG) renin is high in female mice that carry the Rnrs allele and is induced to higher levels by treatment with dihydrotestosterone (DHT). To determine whether the difference in basal activity between high (Rnrs/Rnrs) and low (Rnrb/Rnrb) strains is due to enhanced sensitivity of Rn...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484623
更新日期:1981-06-01 00:00:00
abstract::Melanoma formation in Xiphophorus hybrids is mediated by a growth factor receptor tyrosine kinase oncogene encoded by the Tu locus. In the wild-type parental fish no tumors occur due to the activity of a locus that regulates the activity of the melanoma oncogene. Molecular identification of this regulatory locus (R) r...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426867
更新日期:1991-12-01 00:00:00
abstract::The genetic and cytogenetic locations of the structural gene (Men) for malic enzyme have been determined. Men maps genetically between kar and ry at 51.73 +/- 0.02. Cytogenetically, Men probably lies in the proximal edge of 87D1,2, based on the results of mapping utilizing a number of deficiencies with breakpoints in ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484624
更新日期:1981-06-01 00:00:00
abstract::The heat stability at 56 C of xanthine oxidase (Xox) from mouse intestine was found to be affected by two factors: (1) Xox which had been partially digested by trypsin was less heat stable than Xox which was protected from digestion by the presence of soybean trypsin inhibitor and phenylmethylsulfonyl fluoride; (2) Xo...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484927
更新日期:1975-10-01 00:00:00
abstract::We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484449
更新日期:1983-06-01 00:00:00
abstract::Information on genetic variation is essential for conservation and stock improvement programs. Seven dinucleotide microsatellite loci were analyzed to reveal genetic variability in three wild populations (Kella beel, Hakaluki haor, and Shobornokhali beel) and one hatchery population of the freshwater walking catfish, ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-007-9102-1
更新日期:2007-10-01 00:00:00
abstract::Heat shock proteins (HSPs), members of molecular chaperones families fulfill essential roles under normal conditions and provide protection and adaptation during and after stress. Among different HSPs, HSP70 kDa family of proteins is most abundant and well-studied in human and mouse but has not yet been characterized ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09994-7
更新日期:2020-08-25 00:00:00
abstract::Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9350-3
更新日期:2010-08-01 00:00:00
abstract::Polysomes from 5.5-day and 6.5-day embryonic chick erythroid cells contain messenger RNA (mRNA) which can be translated into products in a cell-free protein-synthesizing system. The products of the cell-free system coelectrophoresed with carrier globin chains from the cells from which the polysomal pellet was isolated...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00483979
更新日期:1977-10-01 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia associated with insulin resistance and relative insulin deficiency. T2DM is believed to be attributable to the combined effect of genetic and environmental factors. Peroxisome proliferator-activated receptor gamma 2 (PPARγ2) is one of the main c...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-016-9765-6
更新日期:2017-02-01 00:00:00
abstract::Genetic analysis of a polymorphic tissue esterase revealed a new locus (Est-6) with two alleles (Est-6a and Est-6b) on linkage group VI of the rabbit. Est-6 is closely linked to the Est-1,2,4 cluster. Esterase of Est-6 is found in many organs, particularly in liver and small intestine, but not in erythrocytes and seru...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554543
更新日期:1987-06-01 00:00:00
abstract::The stem-loop potential of a nucleic acid segment (expressed as a FONS value), decomposes into base composition-dependent and base order-dependent components. The latter, expressed as a FORS-D value, is derived by subtracting the value of the base composition-dependent component (FORS-M) from the FONS value. FORS-D an...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-007-9126-6
更新日期:2008-02-01 00:00:00
abstract::Mitochondrial DNA (mtDNA) hypervariable segment I sequences (HVSI, 471 bp) of the control region and partial cytochrome b sequences (Cytb, 403 bp) were analyzed in three tentative species of the genus Mystacoleucus in China (M. chilopterus, M. marginatus, and M. lepturus). Not more than two mutations were found in bot...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/b:bigi.0000006031.20967.08
更新日期:2003-10-01 00:00:00
abstract::Liver homogenate-supernatants from most Japanese exhibit an "atypical" pH optimum for ethanol oxidation at pH 8.8 instead of 10.5, the "typical" pH-activity optimum. It has been proposed that atypical livers contain alcohol dehydrogenase isozymes with beta 2 subunits while typical livers contain isozymes with beta 1 s...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499296
更新日期:1984-02-01 00:00:00
abstract::Pancreatic cancer is the fourth leading cause of death in both males and females, with a 5-year relative survival rate of 8%. The Wnt signaling pathway has a significant role in the pathogenesis of many tumors, including those of pancreatic cancer. Hypermethylation of the Wnt inhibitory Factor-1 (WIF1) gene promoter h...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-018-9895-0
更新日期:2019-08-01 00:00:00
abstract::The secretogranin II (SCG2) gene is associated with the synthesis and secretion of follicle-stimulating hormone and luteinizing hormone. In the present study, we have determined the complete cDNA sequence of pig SCG2, which was submitted to GenBank with accession no. AY870646. Its complete open reading frame of 1,851 ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9153-y
更新日期:2008-06-01 00:00:00
abstract::Oral cavity cancer belongs to head-and-neck squamous cell carcinoma group. The purpose of the study was to assess the levels of certain proteins in a tumour and surgical margin in a group of patients with oral cavity cancer. The levels of DAPK1, MGMT, CDH1, SFRP1, SFRP2, RORA, TIMP3, p16, APC and RASSF1 proteins were ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-017-9799-4
更新日期:2017-08-01 00:00:00
abstract::We extracted the yellow melanin (phaeomelanin), black melanin (eumelanin), and mixed type of melanin from dorsal hair of dominant yellow (Ay/a), non-agouti (a/a), and agouti (A/A) mice, respectively. Spectrophotometric and fluorescence spectrophotometric analysis demonstrated that the yellow melanin was qualitatively ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484724
更新日期:1978-08-01 00:00:00
abstract::An electrophoretical analysis of blood plasma proteins of eight Anser and two Branta species was performed. Ten polymorphic proteins in blood plasma pattern were distinguished and described: four prealbumin proteins, albumin, three postalbumin proteins, transferrin, and a single posttransferrin protein. Genus-specific...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00557950
更新日期:1995-04-01 00:00:00
abstract::The molecular weight forms of kynurenine formamidase were studied both gentically and biochemically. Formamidase I (native molecular weight 60,000) was purified using (NH4)2SO4 and pH fractionation, DEAE-cellulose chromatography at two different pH's, hydroxylapatite chromatography, and Sephadex G-100 gel filtration. ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484718
更新日期:1978-08-01 00:00:00
abstract::The rice cultivar Hikarishinseiki, a semidwarf isogenotype of Koshihikari carrying the Green Revolution sd1 gene, is increasingly grown in both Japan and the United States. Here, we report DNA diagnosis for Hikarishinseiki targeting its Jukkoku-type sd1 locus, which codes for a defective gibberellin 20-oxidase, with a...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-013-9584-y
更新日期:2013-08-01 00:00:00
abstract::Two complementing loci in different linkage groups of the basidiomycete Ustilago violacea are involved in urease activity: a structural one (ure-1) and a second inferred to involve a permease (ure-2) locus. Two types of complementing mutations occur in the structural locus: null activity (ure-la) and obviously reduced...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484568
更新日期:1981-12-01 00:00:00
abstract::The nucleoside monophosphate kinases, adenylate kinase (AK), guanylate kinase (GUK), and uridine monophosphate kinase (UMPK), were studied electrophoretically and quantitatively in density gradient fractions of human red cells from normal adults which contain red cells of differing mean age. The enzymes were found to ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484542
更新日期:1978-12-01 00:00:00
abstract::Variations at three flight-related enzyme loci, delta-glycerophosphate dehydrogenase (delta-Gpdh), glucose-6-phosphate dehydrogenase (G6pd), and phosphoglucomutase (Pgm), of Epiphyas postvittana (Walker) moths were investigated using starch gel electrophoresis. Among the three enzyme loci, delta-Gpdh and G6pd were fou...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554142
更新日期:1991-08-01 00:00:00