Biochemical genetics of methylglyoxal dehydrogenases in the laboratory rat (Rattus norvegicus).

abstract：:Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, w...

journal_title：Biochemical genetics

authors： Ootsu K,Matsumoto T,Hirano T

更新日期：1976-10-01 00:00:00

abstract：:The aldox-2 locus in Drosophila melanogaster has been shown to affect differentially three molybdoenzymes, aldehyde oxidase, pyridoxal oxidase, and xanthine dehydrogenase. These effects are most obvious at times surrounding the pupal-adult boundary, when the normal organism accumulates large amounts of these enzymes i...

journal_title：Biochemical genetics

authors： Meidinger RG,Bentley MM

更新日期：1986-10-01 00:00:00

abstract：:Malate dehydrogenase (MDH; EC 1.1.1.37) isozymes in long-term callus tissue culture of Cereus peruvianus were studied in starch gel electrophoresis to investigate the control of differential Mdh gene expression under sugar and temperature stress. While two cytosol MDH isozymes showed an unchanged phenotype when the ca...

journal_title：Biochemical genetics

authors： Jorge IC,Mangolin CA,Machado MF

更新日期：1997-06-01 00:00:00

abstract：:Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine wheth...

journal_title：Biochemical genetics

authors： Fang L,Shen B,Irwin DM,Zhang S

更新日期：2014-10-01 00:00:00

abstract：:A new polymorphism, Pc, has been identified in human saliva. Two proteins, Pc 1 and Pc 2, are determined by alleles Pc1 and Pc2, respectively, which show autosomal codominant inheritance. No null phenotype has been encountered in 225 randomly collected salivas. The frequencies of the two alleles differ in the Black an...

journal_title：Biochemical genetics

authors： Karn RC,Goodman PA,Yu PL

更新日期：1985-02-01 00:00:00

abstract：:beta-Glucosidase (beta-D-glucoside glucohydrolase, E.C. 3.2.1.21, beta-Glu) isozyme variants were studied in a large number of inbred lines, crosses, and races of maize (Zea mays L.). The pattern of Mendelian inheritance demonstrated for beta-GLU variants indicated that they are under nuclear gene control. Twenty-two ...

journal_title：Biochemical genetics

authors： Stuber CW,Goodman MM,Johnson FM

更新日期：1977-04-01 00:00:00

abstract：:The stem-loop potential of a nucleic acid segment (expressed as a FONS value), decomposes into base composition-dependent and base order-dependent components. The latter, expressed as a FORS-D value, is derived by subtracting the value of the base composition-dependent component (FORS-M) from the FONS value. FORS-D an...

journal_title：Biochemical genetics

authors： Zhang CY,Wei JF,Wu JS,Xu WR,Sun X,He SH

更新日期：2008-02-01 00:00:00

abstract：:Techniques are presented to detect 23 isozyme loci in the long-lived perennial plant, ponderosa pine. Meiotically derived megagametophyte from seeds is used to examine directly the segregation of allelic variants. Approximately seven seeds were initially examined for 12 enzymes from each of 47 trees from ten stands th...

journal_title：Biochemical genetics

authors： O'Malley DM,Allendorf FW,Blake GM

更新日期：1979-04-01 00:00:00

abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

journal_title：Biochemical genetics

authors： Wu N,Li CJ,Gui JF

更新日期：2009-12-01 00:00:00

abstract：:The cryptic plasmid pGY1, which is harbored by a clinical isolate of Salmonella enterica serovar Paratyphi A, was identified in a 9-year-old girl with paratyphoid fever in 2005, and its DNA sequence was determined. It is 3592 bp in length and had a G+C content of 43.3%. Three ORFs were predicted that share low similar...

journal_title：Biochemical genetics

authors： Huang H,Li J,Yang XL,Wang YG,Wang YP,Tao JS,Huang YZ,Zhang XL

更新日期：2009-04-01 00:00:00

abstract：:Maternal embryo leucine zipper kinase (MELK) has a higher expression level in a variety of cancers and involved in progression of colorectal cancer. The MELK expression levels in colorectal cancer tissues and cells were detected by RT-qPCR. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and transwe...

journal_title：Biochemical genetics

authors： Liu G,Zhan W,Guo W,Hu F,Qin J,Li R,Liao X

更新日期：2020-10-01 00:00:00

abstract：:A bioautographic procedure has been developed for the visualization of the isozymes of dihydrofolate reductase (DHFR, E.C. 1.5.1.3). In addition to detecting electrophoretically separated enzymes, bioautography was utilized to visualize DHFR after isoelectric focusing on polyacrylamide gels. Both zone electrophoresis ...

journal_title：Biochemical genetics

authors： Naylor SL,Townsend JK,Klebe RJ

更新日期：1980-02-01 00:00:00

abstract：:Two complementing loci in different linkage groups of the basidiomycete Ustilago violacea are involved in urease activity: a structural one (ure-1) and a second inferred to involve a permease (ure-2) locus. Two types of complementing mutations occur in the structural locus: null activity (ure-la) and obviously reduced...

journal_title：Biochemical genetics

authors： Baird ML,Garber ED

更新日期：1981-12-01 00:00:00

abstract：:The molecular weight forms of kynurenine formamidase were studied both gentically and biochemically. Formamidase I (native molecular weight 60,000) was purified using (NH4)2SO4 and pH fractionation, DEAE-cellulose chromatography at two different pH's, hydroxylapatite chromatography, and Sephadex G-100 gel filtration. ...

journal_title：Biochemical genetics

authors： Moore GP,Sullivan DT

更新日期：1978-08-01 00:00:00

abstract：:Hippophae rhamnoides ssp. sinensis is endemic to China, and it is a dioecious, outcrossing plant. Although many studies have been undertaken mainly on its agricultural, nutritional, medical, and ornamental value, little is known about its population genetics. This study uses random amplified polymorphic DNA to investi...

journal_title：Biochemical genetics

authors： Sun K,Chen W,Ma R,Chen X,Li A,Ge S

更新日期：2006-06-01 00:00:00

abstract：:The genetic and cytogenetic locations of the structural gene (Men) for malic enzyme have been determined. Men maps genetically between kar and ry at 51.73 +/- 0.02. Cytogenetically, Men probably lies in the proximal edge of 87D1,2, based on the results of mapping utilizing a number of deficiencies with breakpoints in ...

journal_title：Biochemical genetics

authors： Voelker RA,Ohnishi S,Langley CH,Gausz J,Gyurkovics H

更新日期：1981-06-01 00:00:00

abstract：:Genetic variation and differentiation of 12 populations of Picea jezoensis from the Russian Far East were studied using 20 allozyme loci. The mean number of alleles per locus was 2.63, the percent of polymorphic loci was 88.1%, the observed heterozygosity was 0.181, and the mean value of expected heterozygosity amount...

journal_title：Biochemical genetics

authors： Potenko VV

更新日期：2007-04-01 00:00:00

abstract：:DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...

journal_title：Biochemical genetics

authors： Wang D,Tian Y,Wei D,Jing Y,Niu H,Xie K,Song Y

更新日期：2016-04-01 00:00:00

abstract：:Experiments utilizing standard techniques of cell fractionation and disc electrophoresis have revealed the presence of three distinctly different enzymes which catalyze the oxidation of D-sorbitol in crude extracts of Drosophila melanogaster adults. These include (1) a soluble NAD-dependent sorbitol dehydrogenase (NAD...

journal_title：Biochemical genetics

authors： Bischoff WL

更新日期：1976-12-01 00:00:00

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:Inheritance of gliadin components unique to three different varieties of common wheat (Triticum aestivum L.) was studied in F1 and F2 seeds of intervarietal crosses using protein patterns obtained by polyacrylamide gel electrophoresis in aluminum lactate buffer (pH 3.2). The patterns of F1 seeds of the crosses Cheyenn...

journal_title：Biochemical genetics

authors： Mecham DK,Kasarda DD,Qualset CO

更新日期：1978-08-01 00:00:00

abstract：:In flowers of Dianthus caryophyllus (carnation), the gene I is concerned with a discrete step in flavonoid biosynthesis, Genotypes with recessive (ii) alleles produce yellow flowers, which contain the chalcone isosalipurposide (naringenin-chalcone-2'-glucoside) as the major petal pigment, but in genotypes with wild-ty...

journal_title：Biochemical genetics

authors： Forkmann G,Dangelmayr B

更新日期：1980-06-01 00:00:00

abstract：:Using megagametophyte (maternal haploid) and embryo (diploid) tissues of incense-cedar seeds, the expression of one of three malate dehydrogenase (MDH) loci was found to be influenced by a second, unlinked, modifier locus. Whereas alleles of the affected structural locus are codominant, the modifier alleles show domin...

journal_title：Biochemical genetics

authors： Harry DE

更新日期：1983-06-01 00:00:00

abstract：:In corn seedlings (Zea mays L.) homozygous for the mutation gl5, the surface waxes are characteristically altered. In this mutant the main wax constituents (83.5%) are aldehydes while in the normal waxes alcohols predominate (62.7%). Moreover, in the normal waxes aldehydes and alcohols are made up mainly of the C32 te...

journal_title：Biochemical genetics

authors： Bianchi G,Avato P,Salamini F

更新日期：1978-10-01 00:00:00

abstract：:Ade-H and ade-I are two auxotrophic mutants of Chinese hamster ovary (CHO-K1) cells which specifically require adenine as the purine source to grow. The enzymatic defects of these mutants were examined in cell-free extracts. It was found that ade-H did not have any detectable adenylosuccinate synthetase activity and a...

journal_title：Biochemical genetics

authors： Tu AS,Patterson D

更新日期：1977-02-01 00:00:00

abstract：:The quantitative and qualitative distributions of gangliosides were determined in the cerebrum, cerebellum, and brain stem of five inbred strains (C57BL/6J, DBA/2J, LG/J, C3H/HeJ, BALB/cJ) of mice at 21 days of age. Genetic differences were found among the strains for wet weight, absolute amount of gangliosides per re...

journal_title：Biochemical genetics

authors： Seyfried TN,Glaser GH,Yu RK

更新日期：1979-02-01 00:00:00

abstract：:The microRNAs (miRNAs) are involved in multiple pathological processes among various types of tumors. However, the functions of miRNAs in benign brain tumors are largely unexplored. In order to explore the pathogenesis of the invasiveness in non-functional pituitary adenoma (NFPA), the miRNAs expression profile was an...

journal_title：Biochemical genetics

authors： Wu S,Gu Y,Huang Y,Wong TC,Ding H,Liu T,Zhang Y,Zhang X

更新日期：2017-06-01 00:00:00

abstract：:The structural gene locus specifying subunits of cytoplasmic isoenzymes of phosphoglucose isomerase (PGI) is present in duplicate in many diploid species of Clarkia (Onagraceae), a genus of annual plants native to California. We studied the kinetic properties and molecular weights of a large number of genetically defi...

journal_title：Biochemical genetics

authors： Gottlieb LD,Greve LC

更新日期：1981-02-01 00:00:00

abstract：:We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...

journal_title：Biochemical genetics

authors： Ivanenkov VV

更新日期：1983-06-01 00:00:00

abstract：:An Italian organophosphate-resistant strain of Culex pipiens (Lucca) was found to be polymorphic for elevated and nonelevated esterases. Selection for high esterase activity produced a strain homozygous for elevated esterases A2 and B2. Selection for low activity produced a strain homozygous for nonelevated esterases,...

journal_title：Biochemical genetics

authors： Callaghan A,Hemingway J,Malcolm CA

更新日期：1993-12-01 00:00:00