Abstract：
:An Italian organophosphate-resistant strain of Culex pipiens (Lucca) was found to be polymorphic for elevated and nonelevated esterases. Selection for high esterase activity produced a strain homozygous for elevated esterases A2 and B2. Selection for low activity produced a strain homozygous for nonelevated esterases, A4i and B1i. Crossing experiments showed that A2 and B2 are coded by separate but closely linked genes, as are A4i and B1i. Results indicate that elevated A2 and nonelevated A4i are alleles of a single gene (Est-3 locus), as are elevated B2 and nonelevated B1i (Est-2 locus). Selection for electromorph variants gave four elevated A variants and three elevated B variants. These esterases were not selected in the field. In Lucca, A2 and B2 replaced A1, suggesting a selective advantage to the former over the latter in the presence of chlorpyrifos. It is hypothesized that the degree of amplification is an important factor in the selection of a particular esterase electromorph as a resistance mechanism and that migrating individuals with amplified genes could have an advantage when invading a population under selection.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Callaghan A,Hemingway J,Malcolm CAdoi
10.1007/BF02426878subject
Has Abstractpub_date
1993-12-01 00:00:00pages
459-72issue
11-12eissn
0006-2928issn
1573-4927journal_volume
31pub_type
杂志文章abstract：:To determine the genetic structure and variation of Van cats and some other cats, seven enzyme loci were examined using horizontal starch gel electrophoresis. ME bands were observed for the first time in cats. For the enzyme loci CA ( 1 ), SOD, GPI, and GOT, neither the individual Van cats nor the specimens of other c...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-011-9426-8
更新日期：2011-08-01 00:00:00
abstract：:This study deals with the characterization of 10 populations of M. musculus from different geographical locations in India. The genetics of Indian wild mice has been completely obscure and this is the first report on allozyme variations in the natural population. We have used a set of 24 biochemical genetic markers to...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/a:1018781026170
更新日期：1998-08-01 00:00:00
abstract：:Glucose-6-phosphate dehydrogenase (G6PD) deficiency was identified in two children who were studied because of hemolytic episodes. The electrophoretic and kinetic properties of the mutant enzymes allowed us to conclude that both of them were new variants. They were named G6PD Guantánamo and G6PD Caujerí. ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00499316
更新日期：1987-04-01 00:00:00
abstract：:The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484391
更新日期：1980-06-01 00:00:00
abstract：:Considering that the genetically modified soybean lectin gene is affected by the gene type, to improve the stability of the genetically modified soybean lectin gene, a method based on fluorescence quantitative PCR to analyze the genetic characteristics of the genetically modified soybean lectin was proposed. The commo...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-020-09998-3
更新日期：2020-09-26 00:00:00
abstract：:Cleavage patterns of mitochondrial DNAs (mtDNAs) by 15 restriction endonucleases were analyzed for 10 swamp and 13 river types of domestic water buffaloes. Digestions with nine enzymes exhibited polymorphisms giving two or three kinds of cleavage patterns. Five mtDNA types were identified, three types in the swamp buf...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554726
更新日期：1995-06-01 00:00:00
abstract：:Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test u...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00569325
更新日期：1992-08-01 00:00:00
abstract：:A bioautographic procedure has been developed for the visualization of the isozymes of dihydrofolate reductase (DHFR, E.C. 1.5.1.3). In addition to detecting electrophoretically separated enzymes, bioautography was utilized to visualize DHFR after isoelectric focusing on polyacrylamide gels. Both zone electrophoresis ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00504369
更新日期：1980-02-01 00:00:00
abstract：:The secretogranin II (SCG2) gene is associated with the synthesis and secretion of follicle-stimulating hormone and luteinizing hormone. In the present study, we have determined the complete cDNA sequence of pig SCG2, which was submitted to GenBank with accession no. AY870646. Its complete open reading frame of 1,851 ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-008-9153-y
更新日期：2008-06-01 00:00:00
abstract：:The allele, genotype, and haplotype frequencies among 837 Polish Holstein-Friesian cattle were determined at two regulatory indel polymorphisms of the PRNP gene. Allele frequencies at the 23 bp indel promoter polymorphism were 0.622 (del) and 0.378 (ins), with 0.613 and 0.387 in sires and 0.633 and 0.366 in dams. Alle...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-010-9408-2
更新日期：2011-06-01 00:00:00
abstract：:Single-chain variable fragment (scFv) is one of the most common antibody forms. This report describes the expression of the scFv gene as a soluble protein in Origami DE3 cytoplasm. The purified scFv recognized the epidermal growth factor receptor (EGFRvIII) on the surface of MCF-7 cells. The scFv protein was purified ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-012-9506-4
更新日期：2012-08-01 00:00:00
abstract：:UMP synthase was characterized biochemically in dairy cattle heterozygous for a deficiency of this enzyme. Both activities comprising this bifunctional enzyme are decreased, with OMP decarboxylase more affected than orotate phosphoribosyltransferase. Immunotitration of UMP synthase activity revealed the presence of th...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554349
更新日期：1987-08-01 00:00:00
abstract：:Three new linkage groups of enzyme loci are described using Poeciliopsis monacha x P. viriosa-derived interspecific backcross hybrids. Comparison to known linkage groups of the confamilial genus Xiphophorus shows homology between Xiphophorus linkage group I and Poeciliopsis linkage group III, Xiphophorus linkage group...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554823
更新日期：1990-02-01 00:00:00
abstract：:Human PQBP-1 is known to interact with triplet repeat disease gene products such as ataxin and huntingtin through their poly-glutamine (poly-Q) tracts. The poly-Q tracts show extensive variation in both the number and the configuration of repeats among species. A surface plasmon resonance assay showed clear interactio...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-011-9473-1
更新日期：2012-04-01 00:00:00
abstract：:The autoregulation of testicular luteinizing hormone (LH) receptors was studied in hypogonadal (hpg/hpg) and normal mice. The basal concentration of LH receptors was more than three-fold higher in hpg/hpg than in normal mice. After injection of hCG, hpg/hpg mice showed a decrease in LH receptor levels which was not ob...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484511
更新日期：1984-06-01 00:00:00
abstract：:Human cells irradiated with UV light synthesize lower molecular weight DNA than unirradiated cells. This reduction in molecular weight is greater in xeroderma pigmentosum (XP) cells than in normal cells. The molecular weight of DNA is further reduced by the addition of caffeine to XP cells. By several hours after irra...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00504267
更新日期：1981-04-01 00:00:00
abstract：:The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important role...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-008-9166-6
更新日期：2008-08-01 00:00:00
abstract：:Information on genetic variation is essential for conservation and stock improvement programs. Seven dinucleotide microsatellite loci were analyzed to reveal genetic variability in three wild populations (Kella beel, Hakaluki haor, and Shobornokhali beel) and one hatchery population of the freshwater walking catfish, ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-007-9102-1
更新日期：2007-10-01 00:00:00
abstract：:The ribosomal RNA cistrons of three species of trout: Salvelinus namaycush (lake trout), Salvelinus fontinalis (brook trout), and Salmo gairdneri (rainbow trout) were examined by Southern blot analysis of genomic DNA. The repeat length of the cistron of S. namaycush is 26 kb. A repeat-length polymorphism was observed ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00499943
更新日期：1985-12-01 00:00:00
abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-009-9274-y
更新日期：2009-12-01 00:00:00
abstract：:The genetic differentiation among the populations of the European abalone Haliotis tuberculata was investigated using different markers to better understand the evolutionary history and exchanges between populations. Three markers were used: mitochondrial cytochrome oxidase I (COI), the sperm lysin nuclear gene, and e...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-016-9778-1
更新日期：2017-04-01 00:00:00
abstract：:Electrophoretic variation is described for malic enzyme (ME) for the first time in brook trout (Salvelinus fontinalis). Since the quaternary structure of ME was not clear from examination of banding patterns in brook trout alone, ME phenotypes in rainbow trout (Salmo gairdneri)X brook trout hybrids as wel as in esoci...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00502121
更新日期：1979-08-01 00:00:00
abstract：:To elucidate the phylogeny of the genus Paramesotriton (Caudata: Salamandridae), we investigated three mitochondrial DNA gene fragments (1207 bp in total) of cytochrome b, ND2, and ND4 for its six recognized species. The phylogenetic relationships within Paramesotriton were reconstructed by maximum parsimony (MP) and ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/b:bigi.0000026630.78770.fb
更新日期：2004-06-01 00:00:00
abstract：:In flowers of Dianthus caryophyllus (carnation), the gene I is concerned with a discrete step in flavonoid biosynthesis, Genotypes with recessive (ii) alleles produce yellow flowers, which contain the chalcone isosalipurposide (naringenin-chalcone-2'-glucoside) as the major petal pigment, but in genotypes with wild-ty...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484399
更新日期：1980-06-01 00:00:00
abstract：:The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained wer...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554529
更新日期：1986-12-01 00:00:00
abstract：:Among the European fauna, the Sardinian hare (Lepus sp.) is peculiar in that it differs from all other hares inhabiting the continent. Here, we report on the variation of a 461 bp sequence of hypervariable domain 1 of the mitochondrial control region, examined in 42 hares collected throughout Sardinia and compared to ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-007-9076-z
更新日期：2007-04-01 00:00:00
abstract：:A method for detecting two alleles at Np-1 (nucleoside phosphorylase) and three alleles at Es-10 (esterase 10) from mouse blood by cellulose acetate electrophoresis is described. The allelic constitution at these loci for 44 inbred strains and stocks was determined. The location of Np-1 on chromosome 14 was establishe...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484465
更新日期：1977-04-01 00:00:00
abstract：:Imprinted genes are characterized by monoallelic expression that is dependent on parental origin. Comparative analysis of imprinted genes between species is a powerful tool for understanding the biological significance of genomic imprinting. The slc38a4 gene encodes a neutral amino acid transporter and is identified a...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-018-9866-5
更新日期：2018-12-01 00:00:00
abstract：:Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-019-09929-x
更新日期：2019-10-01 00:00:00
abstract：:Phenol sulfotransferase (PST) catalyzes the sulfate conjugation of catechol and phenolic drugs and xenobiotic compounds. Platelets and other tissues contain at least two forms of PST, forms that have been designated the "TL" and the "TS" forms. We measured the thermal stability of platelet TS PST in blood samples from...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00499627
更新日期：1984-12-01 00:00:00
