Abstract：
:Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine whether Gys1 has undergone adaptive evolution in bats with carbohydrate-rich diets, in comparison to insect-eating sister bat taxa, we sequenced the coding region of the Gys1 gene from 10 species of bats, including two Old World fruit bats (Pteropodidae) and a New World fruit bat (Phyllostomidae). Our results show no evidence for positive selection in the Gys1 coding sequence on the ancestral Old World and the New World Artibeus lituratus branches. Tests for convergent evolution indicated convergence of the sequences and one parallel amino acid substitution (T395A) was detected on these branches, which was likely driven by natural selection.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Fang L,Shen B,Irwin DM,Zhang Sdoi
10.1007/s10528-014-9659-4subject
Has Abstractpub_date
2014-10-01 00:00:00pages
443-58issue
9-10eissn
0006-2928issn
1573-4927journal_volume
52pub_type
杂志文章abstract：:Allelic frequencies at five polymorphic loci were determined in seven European and six Afrotropical populations of Drosophila melanogaster. African populations, which may be considered as ancestral for the species, showed a greater genetic diversity as measured by the number of alleles found. Within each geographic gr...
journal_title：Biochemical genetics
pub_type： 杂志文章
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journal_title：Biochemical genetics
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journal_title：Biochemical genetics
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journal_title：Biochemical genetics
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Biochemical genetics
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2007-10-01 00:00:00
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journal_title：Biochemical genetics
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：1990-08-01 00:00:00
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journal_title：Biochemical genetics
pub_type： 杂志文章
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journal_title：Biochemical genetics
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2002-12-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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