Biochemical polymorphisms and genetic relationships in rodents of the genera Oryzomys and Oligoryzomys (Sigmodontinae) from Brazil.

abstract：:Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...

journal_title：Biochemical genetics

authors： Hu S,Zhai P,Chen Y,Zhao B,Yang N,Wang M,Xiao Y,Bao G,Wu X

更新日期：2019-10-01 00:00:00

abstract：:The soluble proteins of the normal and male-sterile stamenless-2 (sl-2/sl-2) mutant of tomato (Lycopersicon esculentum) grown in different temperatures were analyzed by one- and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The normal and mutant stamens had some common proteins, but certai...

journal_title：Biochemical genetics

authors： Sawhney VK,Bhadula SK

更新日期：1987-10-01 00:00:00

abstract：:The segregation of human lysosomal arylsulfatase A (ARS-A) has been evaluated in 50 primary hybrid clones derived from four separate fusions involving WBCs from two unrelated individuals and three hamster cell lines. ARS-A was expressed in the hybrids as a dimeric molecule of very similar or identical subunits. The ex...

journal_title：Biochemical genetics

authors： Bruns GA,Mintz BJ,Leary AC,Regina VM,Gerald PS

更新日期：1979-12-01 00:00:00

abstract：:The interspecies homology of dace supernatant (A2,AB,B2) and mitochondrial (C2) malate dehydrogenase isozymes has been established through cell fractionation and tissue distribution studies. Isolated supernatant malate dehydrogenase (s-MDH) isozymes show significant differences in Michaelis constants for oxaloacetate ...

journal_title：Biochemical genetics

authors： Starzyk RM,Merritt RB

更新日期：1980-08-01 00:00:00

abstract：:Genetic analysis of a polymorphic tissue esterase revealed a new locus (Est-6) with two alleles (Est-6a and Est-6b) on linkage group VI of the rabbit. Est-6 is closely linked to the Est-1,2,4 cluster. Esterase of Est-6 is found in many organs, particularly in liver and small intestine, but not in erythrocytes and seru...

journal_title：Biochemical genetics

authors： van Zutphen LF,den Bieman MG,von Deimling O,Fox RR

更新日期：1987-06-01 00:00:00

abstract：:A major category of mutant hematopoietic phenotypes in Drosophila is melanotic tumors or nodules, which consist of abnormal and overproliferated blood cells, similar to granulomas. Our analyses of the melanotic mutant dappled have revealed a novel type of gene involved in blood cell regulation. The dappled gene is an ...

journal_title：Biochemical genetics

authors： Kleinhesselink K,Conway C,Sholer D,Huang I,Kimbrell DA

更新日期：2011-06-01 00:00:00

abstract：:The extent of naturally occurring variations of enzyme locus expression was determined for three tissues (liver, muscle, and eye) in two species of sunfish (Centrarchidae), the green sunfish (Lepomis cyanellus) and the redear sunfish (L. microlophus). The genetic basis for species differences in tissue enzyme specific...

journal_title：Biochemical genetics

authors： Pasdar M,Philipp DP,Mohammad WA,Whitt GS

更新日期：1984-10-01 00:00:00

abstract：:Site-specific gene modifications in cells are initiated by the introduction of exogenous DNA. We used a recently established cell assay to compare the ability of DNA donors to induce a single point mutation that converts a target gene encoding blue fluorescent protein (BFP) into expressing green fluorescent protein (G...

journal_title：Biochemical genetics

authors： Wagner S,McCracken J,Cole S,Laible G

更新日期：2010-12-01 00:00:00

abstract：:Soluble starch synthase and branching enzyme were purified from 18-day-old cotyledons of the smooth-seeded pea cultivar Alaska (RR) and wrinkled-seeded pea cultivar Progress #9 (rr) by DEAE-cellulose chromatography. Two coeluting peaks of primed and citrate-stimulated starch synthase activity and a major and minor pea...

journal_title：Biochemical genetics

authors： Matters GL,Boyer CD

更新日期：1982-10-01 00:00:00

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:Liver homogenate-supernatants from most Japanese exhibit an "atypical" pH optimum for ethanol oxidation at pH 8.8 instead of 10.5, the "typical" pH-activity optimum. It has been proposed that atypical livers contain alcohol dehydrogenase isozymes with beta 2 subunits while typical livers contain isozymes with beta 1 s...

journal_title：Biochemical genetics

authors： Yin SJ,Bosron WF,Li TK,Ohnishi K,Okuda K,Ishii H,Tsuchiya M

更新日期：1984-02-01 00:00:00

abstract：:An anonymous honey bee locus, detected previously with a cloned probe, has HhaI RFLP alleles specific to African bees or common to both African and European bees. To facilitate identification of these alleles, this region, 1231, was made analyzable with the PCR. The two halves of the region, excluding the termini, wer...

journal_title：Biochemical genetics

authors： Hall HG

更新日期：1998-10-01 00:00:00

abstract：:The goals of this study were to analyze the change in the global gene expression profile of exogenous human leukocyte antigen-G1 (HLA-G1) overexpressed in human embryonic stem (hES) cells and to explore the molecular mechanism by which the overexpression of HLA-G1 modifies immunologic pathways. Microarray and quantita...

journal_title：Biochemical genetics

authors： Zhu Y,Zhao S,Zhao H,Yao Y

更新日期：2012-10-01 00:00:00

abstract：:We have examined the linkage relationships between five biochemical markers, Acon-1, Ahd-2, Ahd-c, Akp-1, and Hao-1, and 19 other genetic loci in five breeding combinations. The genetic locus that codes for a recently described aldehyde dehydrogenase in the liver (Ahd-c) has been assigned to linkage group X (LG X). Hy...

journal_title：Biochemical genetics

authors： Cramer DV,Mowery PA,Adams M

更新日期：1986-04-01 00:00:00

abstract：:A novel cDNA fragment was identified from a human fetal brain cDNA library by using the coding sequence of human BRI3 gene (Accession No. NM015379) as bait in a yeast two-hybrid screening. Then by 5'-RACE (rapid amplification of cDNA end) and electronic hybridization, we obtained a 1.9 kb contig which consists of a no...

journal_title：Biochemical genetics

authors： Lin L,Wu Y,Li C,Zhao S

更新日期：2001-12-01 00:00:00

abstract：:A genetic locus controlling the electrophoretic mobility of a methylglyoxal dehydrogenase (EC 1.2.1.23) in the rat is described. The locus, designated Mgd1, is expressed in liver and kidney. Inbred rat strains have fixed either allele Mgd1a or allele Mgd1b. Codominant expression is observed in heterozygotes, providing...

journal_title：Biochemical genetics

authors： Bender K,Seibert RT,Wienker TF,Kren V,Pravenec M,Bissbort S

更新日期：1994-06-01 00:00:00

abstract：:The genetic diversity of the Turkish native chicken breeds Denizli and Gerze was evaluated with 10 microsatellite markers. We genotyped a total of 125 individuals from five subpopulations. Among loci, the mean number of alleles was 7.5, expected heterozygosity (H (e)) was 0.665, PIC value was 0.610, and Wright's fixat...

journal_title：Biochemical genetics

authors： Kaya M,Yildiz MA

更新日期：2008-08-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is a hematopoietic stem cell malignancy characterized by the expression of the BCR-ABL1 fusion gene with different chimeric transcripts. Despite the crucial impact of constitutively active tyrosine kinase in CML pathogenesis, aberrant DNA methylation of certain genes plays an important r...

journal_title：Biochemical genetics

authors： Behzad MM,Shahrabi S,Jaseb K,Bertacchini J,Ketabchi N,Saki N

更新日期：2018-06-01 00:00:00

abstract：:A null mutation at the phosphoglucomutase locus (Pgm-1) was discovered by electrophoretic analysis of the inbred mouse strain C57BL/6J. The null allele (Pgm-1n) was shown to segregate as a Mendelian unit alternative to the Pgm-1a and Pgm-1b alleles. Mice expressing the Pgm-1n allele, either in the heterozygous or homo...

journal_title：Biochemical genetics

authors： Johnson FM,Hendren RW,Chasalow F,Barnett LB,Lewis SE

更新日期：1981-06-01 00:00:00

abstract：:Non-alcoholic fatty liver disease is one of the main causes of chronic liver disease and therefore is currently considered a major public health problem. Sirtuin 1 (SIRT1) is an NAD-dependent deacetylase enzyme that contributes in the regulation of metabolic processes and protects against lipid accumulation in hepatoc...

journal_title：Biochemical genetics

authors： Borji M,Nourbakhsh M,Shafiee SM,Owji AA,Abdolvahabi Z,Hesari Z,Ilbeigi D,Seiri P,Yousefi Z

更新日期：2019-08-01 00:00:00

abstract：:The retinal pigment epithelium (RPE) plays a key role in the maintenance of the normal functions of the retina. Tissue engineering using amniotic membrane as a substrate to culture RPE cells may provide a promising new strategy to replace damaged RPE. We established a method of culturing RPE cells over the amniotic me...

journal_title：Biochemical genetics

authors： Akrami H,Soheili ZS,Sadeghizadeh M,Khalooghi K,Ahmadieh H,Kanavi MR,Samiei S,Pakravesh J

更新日期：2011-06-01 00:00:00

abstract：:A mouse mutant with pyruvate kinase (PK) hyperactivity has been found in offspring of 1-ethyl-1-nitrosourea (ENU)-treated male mice. The activity alteration was detected in the blood and could also be found in the liver but not in the muscle, kidney, heart, spleen, lung, or brain. Heterozygous mice have erythrocyte PK...

journal_title：Biochemical genetics

authors： Charles DJ,Pretsch W

更新日期：1984-12-01 00:00:00

abstract：:Oral cancer is a multifactorial disease process and involves complex interactions between gene to gene and gene to environmental factors. Interleukin 8 (IL-8), a pro-inflammatory cytokine, having angiogenic activity with elevated expression in tumor cells, is reported to play an essential role in oral cancer developme...

journal_title：Biochemical genetics

authors： Singh PK,Chandra G,Bogra J,Gupta R,Kumar V,Hussain SR,Jain A,Mahdi AA,Ahmad MK

更新日期：2016-02-01 00:00:00

abstract：:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) exhibit genetic polymorphism and tissue specificity. ADH and ALDH isozyme phenotypes from 39 surgical Chinese lung specimens were identified by agarose isoelectric focusing. The identity of the lung beta-ADHs was further demonstrated by their characteristic...

journal_title：Biochemical genetics

authors： Yin SJ,Liao CS,Chen CM,Fan FT,Lee SC

更新日期：1992-04-01 00:00:00

abstract：:ZFY-like genes have been observed in a variety of vertebrate species. Although originally implicated as the primary testis-determining gene in humans and other placental mammals, more recent evidence indicates a role(s) outside that of testis determination. In this study, DNA from five species of fish, Carasius auratu...

journal_title：Biochemical genetics

authors： Zimmerer EJ,Threlkeld L

更新日期：1995-08-01 00:00:00

abstract：:Alcohol dehydrogenase class IV (ADH4) participates in retinol metabolism and is expressed primarily in ocular, digestive, and reproductive tissues of the mouse. A naturally occurring genetic variant in C57BL/6J mice results in a faster migrating ADH4 enzyme during electrophoresis when compared to other non-C57BJ/6J st...

journal_title：Biochemical genetics

authors： Dolney DE,Szalai G,Felder MR

更新日期：2001-08-01 00:00:00

abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

journal_title：Biochemical genetics

authors： Wu N,Li CJ,Gui JF

更新日期：2009-12-01 00:00:00

abstract：:The genetic linkage relationships of the human glycosphingolipid beta-galactosidases were determined using human--mouse somatic cell hybrids. A new method was devised for the estimation of human galactosylceramide, lactosylceramide, and GMI-ganglioside beta-galactosidase activities in the presence of their mouse count...

journal_title：Biochemical genetics

authors： Rushton AR,Dawson G

更新日期：1977-12-01 00:00:00

abstract：:The inducibility of alcohol dehydrogenase (ADH) has been recognized in different systems including maize, Drosophila, and mice. Our earlier results showed strain-specific ADH responses to chronic ethanol administration relative to matched littermate controls in mice. For this study we used two strains which showed "in...

journal_title：Biochemical genetics

authors： Wang CH,Singh SM

更新日期：1984-08-01 00:00:00

abstract：:Tissue-specific catalase activity in 3-week-old animals from inbred mouse strains 129/ReJ, BALB/c, C3H/HeAnl/Cas-1b, C3H/HeSnJ, C3H/S, C57BL/6J, and Swiss-Webster was found to be highly variable by analysis of variance (P = 0.01). Appropriate crosses were made among strains which were classified as normal (BALB/c, C3H...

journal_title：Biochemical genetics

authors： Schisler NJ,Singh SM

更新日期：1991-02-01 00:00:00