Aberrant DNA Methylation in Chronic Myeloid Leukemia: Cell Fate Control, Prognosis, and Therapeutic Response.

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:Experiments utilizing standard techniques of cell fractionation and disc electrophoresis have revealed the presence of three distinctly different enzymes which catalyze the oxidation of D-sorbitol in crude extracts of Drosophila melanogaster adults. These include (1) a soluble NAD-dependent sorbitol dehydrogenase (NAD...

journal_title：Biochemical genetics

authors： Bischoff WL

更新日期：1976-12-01 00:00:00

abstract：:Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...

journal_title：Biochemical genetics

authors： Hu S,Zhai P,Chen Y,Zhao B,Yang N,Wang M,Xiao Y,Bao G,Wu X

更新日期：2019-10-01 00:00:00

abstract：:Electrophoretic variation is described for malic enzyme (ME) for the first time in brook trout (Salvelinus fontinalis). Since the quaternary structure of ME was not clear from examination of banding patterns in brook trout alone, ME phenotypes in rainbow trout (Salmo gairdneri)X brook trout hybrids as wel as in esoci...

journal_title：Biochemical genetics

authors： Stoneking M,May B,Wright JE Jr

更新日期：1979-08-01 00:00:00

abstract：:Genetic variation at three dipeptidase loci (Dip-A, Dip-B, and Dip-C) in Drosophila simulans was analyzed by starch gel electrophoresis. Dip-A was found to be polymorphic in four populations, while Dip-B and Dip-C were found to be polymorphic in one. The numbers of different alleles found at each respective locus were...

journal_title：Biochemical genetics

authors： Ohnishi S,Voelker RA

更新日期：1981-02-01 00:00:00

abstract：:The East Himalaya-Hengduan Mountains region is the center of diversity of the genus Primula, and P. sikkimensis is one of the most common members of the genus in the region. In this study, the genetic diversity and structure of P. sikkimensis populations in China were assessed using inter-simple sequence repeat (ISSR)...

journal_title：Biochemical genetics

authors： Wang FY,Ge XJ,Gong X,Hu CM,Hao G

更新日期：2008-02-01 00:00:00

abstract：:The nucleoside monophosphate kinases, adenylate kinase (AK), guanylate kinase (GUK), and uridine monophosphate kinase (UMPK), were studied electrophoretically and quantitatively in density gradient fractions of human red cells from normal adults which contain red cells of differing mean age. The enzymes were found to ...

journal_title：Biochemical genetics

authors： Jamil TP,Swallow DM,Povey S

更新日期：1978-12-01 00:00:00

abstract：:ZFY-like genes have been observed in a variety of vertebrate species. Although originally implicated as the primary testis-determining gene in humans and other placental mammals, more recent evidence indicates a role(s) outside that of testis determination. In this study, DNA from five species of fish, Carasius auratu...

journal_title：Biochemical genetics

authors： Zimmerer EJ,Threlkeld L

更新日期：1995-08-01 00:00:00

abstract：:Active-site tryptic peptides were isolated from three genetic types of human serum cholinesterase. The active-site peptide was identified by labeling the active-site serine with [3H]diisopropylfluorophosphate. Peptides were purified by high-performance liquid chromatography. Amino acid composition and sequence analysi...

journal_title：Biochemical genetics

authors： Lockridge O,La Du BN

更新日期：1986-06-01 00:00:00

abstract：:beta-Glucosidase (beta-D-glucoside glucohydrolase, E.C. 3.2.1.21, beta-Glu) isozyme variants were studied in a large number of inbred lines, crosses, and races of maize (Zea mays L.). The pattern of Mendelian inheritance demonstrated for beta-GLU variants indicated that they are under nuclear gene control. Twenty-two ...

journal_title：Biochemical genetics

authors： Stuber CW,Goodman MM,Johnson FM

更新日期：1977-04-01 00:00:00

abstract：:In this study, the geographic patterns of genetic variation of three rodent species belonging to the tribe Oryzomyini were investigated using the mitochondrial cytochrome b and nuclear IRBP genes in biomes that are undergoing degradation processes to a greater or lesser degree. The samples are from 25 collecting local...

journal_title：Biochemical genetics

authors： Miranda GB,Andrades-Miranda J,Oliveira LF,Langguth A,Mattevi MS

更新日期：2007-12-01 00:00:00

abstract：:The immunological cross-reactivity of heterogeneous acid phosphatase isozymes from different human tissues has been studied using monospecific antisera prepared against four homogeneous acid phosphatases. The enzyme characterized as tartrate-inhibitable, prostatic acid phosphatase is also found to be present in leukoc...

journal_title：Biochemical genetics

authors： Waheed A,Van Etten RL,Gieselmann V,von Figura K

更新日期：1985-04-01 00:00:00

abstract：:Myogenic differentiation 1 (MyoD1) genes belong to the MyoD gene family and play key roles in growth and muscle development. This study was designed to investigate the effects of variants in the MyoD1 gene on duck growth and carcass traits. Three duck populations (Cherry Valley, Jingjiang, and Muscovy) were sampled, t...

journal_title：Biochemical genetics

authors： Wu Y,Pi JS,Pan AL,Pu YJ,Du JP,Shen J,Liang ZH,Zhang JR

更新日期：2012-12-01 00:00:00

abstract：:Considering that the genetically modified soybean lectin gene is affected by the gene type, to improve the stability of the genetically modified soybean lectin gene, a method based on fluorescence quantitative PCR to analyze the genetic characteristics of the genetically modified soybean lectin was proposed. The commo...

journal_title：Biochemical genetics

authors： Wang Z,Jia H,Yu H,Wang T,Yang B

更新日期：2020-09-26 00:00:00

abstract：:The variable numbers of tandem repeats (VNTR) locus D1S80, located on chromosome 1 (1p35-36), has a repeat unit 16 bp in length, and different numbers of these repeat units have been observed for populations of different origins and ethnicity. We used a molecular identification method based on capillary electrophoresi...

journal_title：Biochemical genetics

authors： Köseler A,Atalay A,Atalay EO

更新日期：2009-08-01 00:00:00

abstract：:The tissue distribution of activin receptor-like kinase 7 (Alk7) expression, the signaling ability of Alk7 variants, and Alk7 expression in response to β3-adrenergic receptor activation were examined. Expression levels of Alk7 varied greatly among tissues but were highest in white adipose tissue and brown adipose tiss...

journal_title：Biochemical genetics

authors： Murakami M,Shirai M,Ooishi R,Tsuburaya A,Asai K,Hashimoto O,Ogawa K,Nishino Y,Funaba M

更新日期：2013-04-01 00:00:00

abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

journal_title：Biochemical genetics

authors： Wu N,Li CJ,Gui JF

更新日期：2009-12-01 00:00:00

abstract：:Species in the genus Oryza (Poaceae) contain 10 genomic types and are distributed in pan-tropics of the world. To explore phylogenetic relationships of Oryza species having the AA-genome, DNA sequences of the chloroplast trnL intron and trnL-trnF spacer, mitochondrial nad1 intron 2, and nuclear internal transcribed sp...

journal_title：Biochemical genetics

authors： Duan S,Lu B,Li Z,Tong J,Kong J,Yao W,Li S,Zhu Y

更新日期：2007-02-01 00:00:00

abstract：:Investigations of an euploid series of castor bean, Ricinus communis L., Consisting of haploid, diploid, and tetraploid individuals, was performed to determine the value of such a series in studying the biochemical consequences of genome multiplication. The effects of euploidization of the nuclear genome on the biosyn...

journal_title：Biochemical genetics

authors： Timko MP,Vasconcelos AC,Fairbrothers DE

更新日期：1980-02-01 00:00:00

abstract：:The heat stability at 56 C of xanthine oxidase (Xox) from mouse intestine was found to be affected by two factors: (1) Xox which had been partially digested by trypsin was less heat stable than Xox which was protected from digestion by the presence of soybean trypsin inhibitor and phenylmethylsulfonyl fluoride; (2) Xo...

journal_title：Biochemical genetics

authors： Arnold CJ,Lush IE

更新日期：1975-10-01 00:00:00

abstract：:The structural characterization of a third type of alpha chain, detected in the hemoglobin of sheep also possessing the alpha Leu and the II alpha His chains, is reported. The new alpha-chain variant is an allele of the common alpha Leu chain controlled by the 1 alpha locus and differs from it in the replacement of th...

journal_title：Biochemical genetics

authors： Vestri R,Giordano PC,Bernini LF

更新日期：1983-02-01 00:00:00

abstract：:The structural gene locus specifying subunits of cytoplasmic isoenzymes of phosphoglucose isomerase (PGI) is present in duplicate in many diploid species of Clarkia (Onagraceae), a genus of annual plants native to California. We studied the kinetic properties and molecular weights of a large number of genetically defi...

journal_title：Biochemical genetics

authors： Gottlieb LD,Greve LC

更新日期：1981-02-01 00:00:00

abstract：:A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific antisera. The concentration of Hb-F-Malta-I was 0.002-0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%, compared to a rat...

journal_title：Biochemical genetics

authors： Altay G,Garver F,Bannister WH,Grech JL,Felice A,Huisman TH

更新日期：1977-10-01 00:00:00

abstract：:We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...

journal_title：Biochemical genetics

authors： Ivanenkov VV

更新日期：1983-06-01 00:00:00

abstract：:An anonymous honey bee locus, detected previously with a cloned probe, has HhaI RFLP alleles specific to African bees or common to both African and European bees. To facilitate identification of these alleles, this region, 1231, was made analyzable with the PCR. The two halves of the region, excluding the termini, wer...

journal_title：Biochemical genetics

authors： Hall HG

更新日期：1998-10-01 00:00:00

abstract：:Fifty-six sequences encoding the pina protein were characterized from three species or subspecies of einkorn wheat. These sequences contained 1,595 nucleotides, including 1,270 conserved sites, 21 single nucleotide polymorphisms (SNPs), and 16 indels. The average frequency of SNPs and indels was one out of 76.1 and 99...

journal_title：Biochemical genetics

authors： Chen Q,Qi PF,Wei YM,Wang JR,Zheng YL

更新日期：2009-06-01 00:00:00

abstract：:In Neurospora crassa, the expression of unlinked structural genes which encode nitrogen catabolic enzymes is subject to genetic and metabolic regulation. The negative-acting nmr regulatory gene appears to play a role in nitrogen catabolite repression. Using the N. crassa nmr gene as a probe, homologous sequences were ...

journal_title：Biochemical genetics

authors： Young JL,Marzluf GA

更新日期：1991-10-01 00:00:00

abstract：:Genetic diversity and genetic structure within and among ten populations of Stephania yunnanensis H. S. Lo and three populations of S. epigaea H. S. Lo from Yunnan province were evaluated by direct amplification of length polymorphism (DALP) markers. Five primer groups were screened, and a total of 287 DNA fragments w...

journal_title：Biochemical genetics

authors： Ma YS,Yu H,Li YY,Yan H,Cheng X

更新日期：2008-04-01 00:00:00

abstract：:The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...

journal_title：Biochemical genetics

authors： Donald LJ,Wang HS,Hamerton JL

更新日期：1980-06-01 00:00:00

abstract：:Polymorphic esterase and acetylcholinesterase alleles in the whitefly Bemisia tabaci were studied using electrophoretic and colorimetric assays. The segregation of these alleles between parental and F1 generations provided unequivocal evidence of haplodiploidy in this pest species. Unmated females, heterozygous at a p...

journal_title：Biochemical genetics

authors： Byrne FJ,Devonshire AL

更新日期：1996-04-01 00:00:00