Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes.

abstract：:Fourteen myoglobins of known sequence were examined by isoelectric focusing with and without urea. The 14 sequences formed six distinct mobility classes on gels without urea and three classes on those with urea. For these proteins, isoelectric focusing provides no advantage over single, nonequilibrium, nondenaturing g...

journal_title：Biochemical genetics

authors： McLellan T,Inouye LS

更新日期：1986-08-01 00:00:00

abstract：:The ratio of cellular RNA and protein content is about 1:1 between phylogenetically diploid and tetraploid species of the teleost family Cyprinidae, but is roughly in proportion to ploidy in species of the teleost order Isospondyli. Enzyme activities do not unequivocally comply with this scheme. These findings are dis...

journal_title：Biochemical genetics

authors： Schmidtke J,Schulte B,Kuhl P,Engel W

更新日期：1976-12-01 00:00:00

abstract：:Considering that the genetically modified soybean lectin gene is affected by the gene type, to improve the stability of the genetically modified soybean lectin gene, a method based on fluorescence quantitative PCR to analyze the genetic characteristics of the genetically modified soybean lectin was proposed. The commo...

journal_title：Biochemical genetics

authors： Wang Z,Jia H,Yu H,Wang T,Yang B

更新日期：2020-09-26 00:00:00

abstract：:An electrophoretic analysis of 12 allozyme systems (14 loci, 40 alleles) was performed in the rodent genera Oryzomys and Oligoryzomys, in order to determine the levels of genetic variability within and among populations and species. One hundred and fifty-five individuals from 16 populations of Oryzomys russatus, Or. a...

journal_title：Biochemical genetics

authors： Perini MV,Weimer TA,Callegari-Jacques SM,Mattevi MS

更新日期：2004-10-01 00:00:00

abstract：:Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...

journal_title：Biochemical genetics

authors： Mashayekhi F,Shafiee G,Kazemi M,Dolati P

更新日期：2010-08-01 00:00:00

abstract：:Luo [Biochem. Genet. 43:223-227] concluded, "The mutation ALDH2(() 487Lys allele is not deleterious but is of great benefit to human health." This statement is easily subject to misinterpretation and needs to be clarified. Their results actually show there is a pleiotropic effect associated with the mutation ALDH2(() ...

journal_title：Biochemical genetics

authors： Sinclair D

更新日期：2006-10-01 00:00:00

abstract：:DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...

journal_title：Biochemical genetics

authors： Wang D,Tian Y,Wei D,Jing Y,Niu H,Xie K,Song Y

更新日期：2016-04-01 00:00:00

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:The immunological cross-reactivity of heterogeneous acid phosphatase isozymes from different human tissues has been studied using monospecific antisera prepared against four homogeneous acid phosphatases. The enzyme characterized as tartrate-inhibitable, prostatic acid phosphatase is also found to be present in leukoc...

journal_title：Biochemical genetics

authors： Waheed A,Van Etten RL,Gieselmann V,von Figura K

更新日期：1985-04-01 00:00:00

abstract：:Eight Drosophila melanogaster strains, seven homozygous for AdhF alleles and one for an Adh-null mutant, were compared for ADH activity in males and adult mortality on ethanol-supplemented food. The strains differed considerably in these qualities. A positive correlation was found between ADH activity and LD50. The re...

journal_title：Biochemical genetics

authors： Kamping A,van Delden W

更新日期：1978-06-01 00:00:00

abstract：:A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific antisera. The concentration of Hb-F-Malta-I was 0.002-0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%, compared to a rat...

journal_title：Biochemical genetics

authors： Altay G,Garver F,Bannister WH,Grech JL,Felice A,Huisman TH

更新日期：1977-10-01 00:00:00

abstract：:Male and female wild Norway rats (Rattus norvegicus Erxleben) and male and female albino outbred rats (Ipf:RIZ) were crossbred. These animals were the control, noninbred group (0% inbred). By systematic full-sib mating, two experimental groups (50 and 91% of inbred) were raised. Half of each group (both males and fema...

journal_title：Biochemical genetics

authors： Kosowska B

更新日期：1992-08-01 00:00:00

abstract：:A new variant of hereditary hemolytic anemia in a family due to high adenosine triphosphate (ATP) is reported. The increase in ATP levels varied from 83 to 105% in the family members. Low 2,3-diphosphoglycerate levels and low 2,3-diphosphoglyceromutase activity were observed in three family members, with normal glucos...

journal_title：Biochemical genetics

authors： Bapat JP,Baxi AJ

更新日期：1981-10-01 00:00:00

abstract：:In order to clarify the genetic linkage groups of the Japanese brown frog Rana japonica, and compare them with those of other vertebrates, the inheritance of 10 enzyme and blood protein loci was examined in 267 offspring derived from 18 crosses using 10 males heterozygous at these loci. Most of the segregation tests e...

journal_title：Biochemical genetics

authors： Sumida M

更新日期：1996-10-01 00:00:00

abstract：:The effects of environmental 2-propanol on the in vivo properties of Drosophila alcohol dehydrogenase (E.C. 1..1.1.1.) are presented. Exposed flies were found to exhibit a significant decrease in ADH specific activity with a concomitant increase in the enzyme's relative in vivo stability and concentration. The possibl...

journal_title：Biochemical genetics

authors： Anderson SM,McDonald JF

更新日期：1981-04-01 00:00:00

abstract：:Information on genetic variation is essential for conservation and stock improvement programs. Seven dinucleotide microsatellite loci were analyzed to reveal genetic variability in three wild populations (Kella beel, Hakaluki haor, and Shobornokhali beel) and one hatchery population of the freshwater walking catfish, ...

journal_title：Biochemical genetics

authors： Islam MN,Islam MS,Alam MS

更新日期：2007-10-01 00:00:00

abstract：:Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of haplotype A in six bre...

journal_title：Biochemical genetics

authors： Zhang B,Chen H,Hua L,Zhang C,Kang X,Wang X,Pan C,Lan X,Lei C

更新日期：2008-06-01 00:00:00

abstract：:A significant challenge in epistasis detection is the huge amount of data, which leads to combinatorial explosion. This study focuses on a two-stage approach for detecting epistasis only among single nucleotide polymorphisms (SNPs) that show some marginal effect. We present this two-stage approach based on the fusion ...

journal_title：Biochemical genetics

authors： Liao Z,Zeng Q,Liao B,Li X

更新日期：2014-10-01 00:00:00

abstract：:Sequence divergence of mitochondrial COII was analyzed in 50 specimens belonging to five subspecies of Polyura eudamippus (Lepidoptera: Nymphalidae) collected from southern China. There were nine haplotypes in the 405 bp of partial COII sequence. Distribution of the five subspecies was primarily consistent with the sp...

journal_title：Biochemical genetics

authors： Long Y,Wan H,Yan F,Xu C,Lei G,Li S,Wang R

更新日期：2006-10-01 00:00:00

abstract：:We report a new enzyme xylose dehydrogenase, the structural locus for which is on chromosome 7 of the mouse, closely linked to Tam-1. Three alleles have been detected in both laboratory strains and wild populations. Two of these determine proteins differing in electrophoretic mobility and the third is a "null." This e...

journal_title：Biochemical genetics

authors： Newton MF,Nash HR,Peters J,Andrews SJ

更新日期：1982-08-01 00:00:00

abstract：:During a large-scale screen of a human fetal brain cDNA library, a full-length cDNA encoding a novel Rap2 interacting protein was isolated and sequenced. The cDNA is 3397bp long and has a predicted open reading frame encoding a protein of 329 aa. The predicted protein shows high homology to mouse and human RPIP8, and ...

journal_title：Biochemical genetics

authors： Wang S,Zhang Z,Ying K,Chen JZ,Meng XF,Yang QS,Xie Y,Mao YM

更新日期：2003-02-01 00:00:00

abstract：:When the 4-bp Dam recognition sequence was placed between two d(GA)7 tracts, it became severely undermethylated in JM101 Escherichia coli cells compared to other Dam sequences in the same plasmid DNA. This site specific undermethylation was also detected on supercoiled molecules in vitro. Mutational analysis indicated...

journal_title：Biochemical genetics

authors： Klysik J

更新日期：1996-06-01 00:00:00

abstract：:Potassium (K+) transport and channel systems play vital roles in plant growth, development and responses to various stresses. In this study, 44 putative K+-transport-related genes (18K+ uptake permease (KUP)/high-affinity K+ (HAK)/K+ transporter (KT) family genes and 26 channel genes, including 18 Shaker family genes ...

journal_title：Biochemical genetics

authors： Shen C,Yuan J

更新日期：2020-09-29 00:00:00

abstract：:Cleavage patterns of mitochondrial DNAs (mtDNAs) by 15 restriction endonucleases were analyzed for 10 swamp and 13 river types of domestic water buffaloes. Digestions with nine enzymes exhibited polymorphisms giving two or three kinds of cleavage patterns. Five mtDNA types were identified, three types in the swamp buf...

journal_title：Biochemical genetics

authors： Tanaka K,Yamagata T,Masangkay JS,Faruque MO,Vu-Binh D,Salundik,Mansjoer SS,Kawamoto Y,Namikawa T

更新日期：1995-06-01 00:00:00

abstract：:Genetic linkage maps are valuable tools for genetic, genomic, and crop breeding studies. Several genetic linkage maps were constructed for the olive (Olea europaea L.) genome, mainly using amplified fragment length polymorphisms (AFLPs) and simple sequence repeat (SSR) markers. However, AFLPs and SSR markers were not ...

journal_title：Biochemical genetics

authors： İpek A,Yılmaz K,Sıkıcı P,Tangu NA,Öz AT,Bayraktar M,İpek M,Gülen H

更新日期：2016-06-01 00:00:00

abstract：:In flowers of Dianthus caryophyllus (carnation), the gene I is concerned with a discrete step in flavonoid biosynthesis, Genotypes with recessive (ii) alleles produce yellow flowers, which contain the chalcone isosalipurposide (naringenin-chalcone-2'-glucoside) as the major petal pigment, but in genotypes with wild-ty...

journal_title：Biochemical genetics

authors： Forkmann G,Dangelmayr B

更新日期：1980-06-01 00:00:00

abstract：:Apodemus peninsulae is a field mouse that inhabits the broad-leafed forests of temperate Eurasia. We examined the mitochondrial cytochrome b gene in 57 in dividuals of A. peninsulae from northeastern Asia, including Siberia, Primorye, Magadan region, Sakhalin, Hokkaido, and the Korean Peninsula. The genealogy of the m...

journal_title：Biochemical genetics

authors： Serizawa K,Suzuki H,Iwasa MA,Tsuchiya K,Pavlenko MV,Kartavtseva IV,Chelomina GN,Dokuchaev NE,Han SH

更新日期：2002-06-01 00:00:00

abstract：:Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test u...

journal_title：Biochemical genetics

authors： Sato H,Sakai Y,Koiwai O,Watanabe T

更新日期：1992-08-01 00:00:00

abstract：:We have isolated the Drosophila melanogaster locus coding for L-glutamate dehydrogenase (EC 1.4.1.3) by virtue of its similarity to the corresponding human gene. There is only one copy of this gene in the fruit fly genome, located on the right arm of chromosome 3 (95D1-4). The transcript includes at least one large in...

journal_title：Biochemical genetics

authors： Papadopoulou D,Louis C

更新日期：1990-08-01 00:00:00

abstract：:Single nucleotide polymorphisms (SNP) in the resistin gene (RETN) are linked to obesity and resistin levels in various populations. However, results have been inconsistent. This study aimed to investigate association between polymorphisms in the resistin gene with obesity in a homogenous Malaysian Malay population. Th...

journal_title：Biochemical genetics

authors： Apalasamy YD,Rampal S,Salim A,Moy FM,Su TT,Majid HA,Bulgiba A,Mohamed Z

更新日期：2015-06-01 00:00:00