Abstract：
:In Neurospora crassa, the expression of unlinked structural genes which encode nitrogen catabolic enzymes is subject to genetic and metabolic regulation. The negative-acting nmr regulatory gene appears to play a role in nitrogen catabolite repression. Using the N. crassa nmr gene as a probe, homologous sequences were identified in a variety of other filamentous fungi. The polymerase chain reaction was used to isolate the nmr-like gene from the exotic Mauriceville strain of N. crassa and from the two related species, N. intermedia and N. sitophila. Sequence comparisons were carried out with a 1.7-kb DNA segment which includes the entire coding region of nmr plus 5' and 3' noncoding sequences. The size of the nmr coding region was identical in all three Neurospora species. Approximately 30 nucleotide base substitutions were found in the coding region of the nmr gene of each of the sister species when compared to the standard N. crassa sequence. However, most of the base changes occurred in third codon positions and were silent. The NMR proteins of N. sitophila and of N. intermedia display only three and four amino acid substitutions, respectively, from the N. crassa protein. Two regions of high variability, which include deletions and insertions of bases, were found in the 5' and 3' noncoding regions of the gene.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Young JL,Marzluf GAsubject
Has Abstractpub_date
1991-10-01 00:00:00pages
447-59issue
9-10eissn
0006-2928issn
1573-4927journal_volume
29pub_type
杂志文章abstract：:The heat stability at 56 C of xanthine oxidase (Xox) from mouse intestine was found to be affected by two factors: (1) Xox which had been partially digested by trypsin was less heat stable than Xox which was protected from digestion by the presence of soybean trypsin inhibitor and phenylmethylsulfonyl fluoride; (2) Xo...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484927
更新日期：1975-10-01 00:00:00
abstract：:Linkage data for the sex-linked malic enzyme (Me) and hexokinase-1 (Hk-1) loci in the flour beetle, Tribolium confusum, were obtained from a three-point experiment involving the red locus. The order of the three loci was determined to be red--Hk-1-Me, with map distances of 12.4 +/- 1.8 for red to Hk-1 and 7.0 +/- 1.3 ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00498914
更新日期：1983-08-01 00:00:00
abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-009-9274-y
更新日期：2009-12-01 00:00:00
abstract：:The concentration of mouse kidney histidine decarboxylase (HDC) is modulated by estrogen, testosterone, and thyroxine in a tissue-specific manner. Variation in HDC levels between strains of mice can be used to investigate the genetic regulation of enzyme structure, tissue specific expression, and induction and repress...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00485850
更新日期：1984-08-01 00:00:00
abstract：:The Wood Stork (Mycteria americana) is a colonial wading bird of the tropical and lower subtropical zones. We assessed genetic structure within and among five stork colonies from the Brazilian Pantanal and compared our data with those from North American populations. Samples of 234 individuals were studied using prote...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/a:1015109321773
更新日期：2002-04-01 00:00:00
abstract：:The variable numbers of tandem repeats (VNTR) locus D1S80, located on chromosome 1 (1p35-36), has a repeat unit 16 bp in length, and different numbers of these repeat units have been observed for populations of different origins and ethnicity. We used a molecular identification method based on capillary electrophoresi...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-009-9250-6
更新日期：2009-08-01 00:00:00
abstract：:Skeletal muscle tissues from many species of salmonid fish are known to exhibit a set of three of five isozymes for A4-type lactate dehydrogenase (L-lactate: NAD oxidoreductase, E.C. 1.1.1.27), but the genetic basis for this isozyme system has not previously been assessed. This isozyme system was purified to homogenei...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484099
更新日期：1977-08-01 00:00:00
abstract：:Congenital heart disease is the most common congenital anomaly, representing an important cause of infant morbidity and mortality. Congenital heart disease represents a group of heart anomalies that include septal defects, valve defects, and outflow tract anomalies. The exact genetic, epigenetic, or environmental basi...
journal_title：Biochemical genetics
pub_type： 杂志文章,评审
doi：10.1007/s10528-016-9780-7
更新日期：2017-04-01 00:00:00
abstract：:Genetic diversity and genetic structure within and among ten populations of Stephania yunnanensis H. S. Lo and three populations of S. epigaea H. S. Lo from Yunnan province were evaluated by direct amplification of length polymorphism (DALP) markers. Five primer groups were screened, and a total of 287 DNA fragments w...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-008-9146-x
更新日期：2008-04-01 00:00:00
abstract：:Environmentally induced flax genotrophs L and S show heritable shifts in the relative mobilities of peroxidase, esterase, and acid phosphatase isozymes, plus a number of nonspecific glycoproteins. All L isozymes migrated faster than corresponding S isozymes in 10% acrylamide gels. Various aspects of these shifts are r...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00499290
更新日期：1984-02-01 00:00:00
abstract：:There are three major groups of domestic cattle in East and Southeast Asia: European cattle, Zebu cattle, and Bali cattle. Ten restriction enzymes were used to analyze restriction site variants in the mitochondrial DNA (mtDNA) in 178 individuals belonging to these three groups of cattle. The results indicate that each...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554558
更新日期：1995-02-01 00:00:00
abstract：:Mitochondrial DNA (mtDNA) from two breeds of cattle, viz., [Hariana (Bos indicus), Holstein (Bos taurus)] and Indian water buffalo (Bubalis bubalus), was analyzed using 13 restriction endonucleases which recognized an average of about 40 six-base sites. Polymorphism among cattle was detected with six of these enzymes....
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF02401421
更新日期：1990-08-01 00:00:00
abstract：:A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific antisera. The concentration of Hb-F-Malta-I was 0.002-0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%, compared to a rat...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00483988
更新日期：1977-10-01 00:00:00
abstract：:Tissue-specific catalase activity in 3-week-old animals from inbred mouse strains 129/ReJ, BALB/c, C3H/HeAnl/Cas-1b, C3H/HeSnJ, C3H/S, C57BL/6J, and Swiss-Webster was found to be highly variable by analysis of variance (P = 0.01). Appropriate crosses were made among strains which were classified as normal (BALB/c, C3H...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00578241
更新日期：1991-02-01 00:00:00
abstract：:We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484449
更新日期：1983-06-01 00:00:00
abstract：:The ratio of cellular RNA and protein content is about 1:1 between phylogenetically diploid and tetraploid species of the teleost family Cyprinidae, but is roughly in proportion to ploidy in species of the teleost order Isospondyli. Enzyme activities do not unequivocally comply with this scheme. These findings are dis...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00485129
更新日期：1976-12-01 00:00:00
abstract：:Investigations of an euploid series of castor bean, Ricinus communis L., Consisting of haploid, diploid, and tetraploid individuals, was performed to determine the value of such a series in studying the biochemical consequences of genome multiplication. The effects of euploidization of the nuclear genome on the biosyn...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00504367
更新日期：1980-02-01 00:00:00
abstract：:To elucidate the phylogeny of the genus Paramesotriton (Caudata: Salamandridae), we investigated three mitochondrial DNA gene fragments (1207 bp in total) of cytochrome b, ND2, and ND4 for its six recognized species. The phylogenetic relationships within Paramesotriton were reconstructed by maximum parsimony (MP) and ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/b:bigi.0000026630.78770.fb
更新日期：2004-06-01 00:00:00
abstract：:The structural gene locus specifying subunits of cytoplasmic isoenzymes of phosphoglucose isomerase (PGI) is present in duplicate in many diploid species of Clarkia (Onagraceae), a genus of annual plants native to California. We studied the kinetic properties and molecular weights of a large number of genetically defi...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00486145
更新日期：1981-02-01 00:00:00
abstract：:We extracted the yellow melanin (phaeomelanin), black melanin (eumelanin), and mixed type of melanin from dorsal hair of dominant yellow (Ay/a), non-agouti (a/a), and agouti (A/A) mice, respectively. Spectrophotometric and fluorescence spectrophotometric analysis demonstrated that the yellow melanin was qualitatively ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484724
更新日期：1978-08-01 00:00:00
abstract：:Oral cavity cancer belongs to head-and-neck squamous cell carcinoma group. The purpose of the study was to assess the levels of certain proteins in a tumour and surgical margin in a group of patients with oral cavity cancer. The levels of DAPK1, MGMT, CDH1, SFRP1, SFRP2, RORA, TIMP3, p16, APC and RASSF1 proteins were ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-017-9799-4
更新日期：2017-08-01 00:00:00
abstract：:Gli-D1-encoded omega gliadins of bread wheats show little variation; their electrophoretic patterns can be classified into two main groups which broadly resemble the patterns found in the cultivars Chinese Spring and in Cheyenne. B and D subunits of low molecular weight glutenin encoded by the chromosome 1D loci Glu-D...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554146
更新日期：1991-08-01 00:00:00
abstract：:The nuclear factor of activated T lymphocytes (NFATc1) plays a critical role during valvular and septal development. Genetic variants may influence the biological function of the protein and thus play a role in susceptibility to valvuloseptal defects. Tandem repeat polymorphisms and a common nonsynonymous polymorphism...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-011-9434-8
更新日期：2011-10-01 00:00:00
abstract：:Two alleles are encoded at the malate dehydrogenase locus in largemouth bass, Micropterus salmoides. Populations in the extreme northern areas of the range of this fish are fixed or nearly fixed for the B1 allele, whereas populations in Florida are fixed for the alternative allele, B2. The MDH-B1B1 and MDH-B2B2 alleli...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00488466
更新日期：1983-12-01 00:00:00
abstract：:Studies on hybridization, inheritance, and population genetics of brown planthoppers that infest rice and weeds were undertaken using starch gel electrophoresis to determine whether the weed-infesting population represents a biological race or a species. F(1) and F(2) generations were produced by crosses between paren...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-009-9316-5
更新日期：2010-04-01 00:00:00
abstract：:The enzyme UDPglucose:flavonol 3-O-glucosyltransferase is shown to be under the coordinate control of three genes involved in anthocyanin biosynthesis in the aleurone of maize: C, R, and BZ. Of the three, BZ appears to be the structural gene. Data presented here (dosage comparisons, induction in the mutant c-p, and ef...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00520194
更新日期：1977-06-01 00:00:00
abstract：:Arylsulfatase A (ASA) activity was studied from five blood fractions, leukocytes plus platelets (LKPL), leukocytes (LK), neutrophils (N), lymphocytes (LYM), and platelets (PL). No significant difference was found among the mean ASA specific activity values for the fractions. Electrophoretic examination revealed four d...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484068
更新日期：1982-10-01 00:00:00
abstract：:Restriction endonuclease analyses of DNA from one Black G gamma A gamma-HPFH homozygote and four Black and one Indian G gamma A gamma-HPFH heterozygotes have identified three different HPFH types which are the result of large deletions including the delta and beta genes. Two of the types are comparable to those charac...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00499284
更新日期：1984-02-01 00:00:00
abstract：:An enzyme catalyzing the transfer of the glucosyl moiety of UDP-glucose to the 3-hydroxyl group of cyanidin has been demonstrated in petal extracts of Silene dioica mutants with cyanidin-3-O-glucoside in the petals. This transferase activity was also present in young rosette leaves and calyces of these plants. The hig...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484525
更新日期：1978-12-01 00:00:00
abstract：:The alpha-amylase in Drosophila melanogaster is a highly polymorphic enzyme, at both the allozyme level and the specific activity level. This enzyme changes its specific activity drastically depending on both food conditions and developmental stages, and it has been suggested that the ability to change its activity de...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/a:1018715528413
更新日期：1999-12-01 00:00:00
