Association of a tandem repeat polymorphism in NFATc1 with increased risk of perimembranous ventricular septal defect in a Chinese population.

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:To elucidate the phylogeny of the genus Paramesotriton (Caudata: Salamandridae), we investigated three mitochondrial DNA gene fragments (1207 bp in total) of cytochrome b, ND2, and ND4 for its six recognized species. The phylogenetic relationships within Paramesotriton were reconstructed by maximum parsimony (MP) and ...

journal_title：Biochemical genetics

authors： Lu S,Yuan ZG,Pang J,Yang D,Yu F,McGuire P,Xie F,Zhang YP

更新日期：2004-06-01 00:00:00

abstract：:Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...

journal_title：Biochemical genetics

authors： Mashayekhi F,Shafiee G,Kazemi M,Dolati P

更新日期：2010-08-01 00:00:00

abstract：:Glutamate-oxaloacetate transaminase (GOT; EC 2.6.1.1) occurs as two electrophoretically distinguishable isozymes in the copepod Tigriopus californicus. The slower-migrating form, referred to as GOT2 , is shown to be associated with the mitochondrial cell fraction. GOT2 phenotypes are inherited in typical Mendelian fas...

journal_title：Biochemical genetics

authors： Dill MM,Burton RS

更新日期：1984-04-01 00:00:00

abstract：:Soluble starch synthase and branching enzyme were purified from 18-day-old cotyledons of the smooth-seeded pea cultivar Alaska (RR) and wrinkled-seeded pea cultivar Progress #9 (rr) by DEAE-cellulose chromatography. Two coeluting peaks of primed and citrate-stimulated starch synthase activity and a major and minor pea...

journal_title：Biochemical genetics

authors： Matters GL,Boyer CD

更新日期：1982-10-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia associated with insulin resistance and relative insulin deficiency. T2DM is believed to be attributable to the combined effect of genetic and environmental factors. Peroxisome proliferator-activated receptor gamma 2 (PPARγ2) is one of the main c...

journal_title：Biochemical genetics

authors： Majid M,Masood A,Kadla SA,Hameed I,Ganai BA

更新日期：2017-02-01 00:00:00

abstract：:The aldox-2 locus in Drosophila melanogaster has been shown to affect differentially three molybdoenzymes, aldehyde oxidase, pyridoxal oxidase, and xanthine dehydrogenase. These effects are most obvious at times surrounding the pupal-adult boundary, when the normal organism accumulates large amounts of these enzymes i...

journal_title：Biochemical genetics

authors： Meidinger RG,Bentley MM

更新日期：1986-10-01 00:00:00

abstract：:Studies have investigated the association between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and cardiometabolic risk factors (CMRFs), however with varying results, which could be due to ethnicity differences. Therefore, the present study was conducted among Bhil tribal population (...

journal_title：Biochemical genetics

authors： Mishra D,Naorem K,Saraswathy KN

更新日期：2018-08-01 00:00:00

abstract：:Differences in Zn-induced levels of hepatic metallothionein (MT) in inbred strains of the mouse are described. Three low-producing strains, C57 BL/6, C57BL/10, and NIH, are identified, while C3H and CBA display the highest levels of hepatic MT following Zn treatment. These interstrain differences affect not only the l...

journal_title：Biochemical genetics

authors： Farr C,Hunt DM

更新日期：1989-04-01 00:00:00

abstract：:The quantitative and qualitative distributions of gangliosides were determined in the cerebrum, cerebellum, and brain stem of five inbred strains (C57BL/6J, DBA/2J, LG/J, C3H/HeJ, BALB/cJ) of mice at 21 days of age. Genetic differences were found among the strains for wet weight, absolute amount of gangliosides per re...

journal_title：Biochemical genetics

authors： Seyfried TN,Glaser GH,Yu RK

更新日期：1979-02-01 00:00:00

abstract：:When the 4-bp Dam recognition sequence was placed between two d(GA)7 tracts, it became severely undermethylated in JM101 Escherichia coli cells compared to other Dam sequences in the same plasmid DNA. This site specific undermethylation was also detected on supercoiled molecules in vitro. Mutational analysis indicated...

journal_title：Biochemical genetics

authors： Klysik J

更新日期：1996-06-01 00:00:00

abstract：:Myogenic differentiation 1 (MyoD1) genes belong to the MyoD gene family and play key roles in growth and muscle development. This study was designed to investigate the effects of variants in the MyoD1 gene on duck growth and carcass traits. Three duck populations (Cherry Valley, Jingjiang, and Muscovy) were sampled, t...

journal_title：Biochemical genetics

authors： Wu Y,Pi JS,Pan AL,Pu YJ,Du JP,Shen J,Liang ZH,Zhang JR

更新日期：2012-12-01 00:00:00

abstract：:The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...

journal_title：Biochemical genetics

authors： Cobb RR,Stoming TA,Whitney JB 3rd

更新日期：1987-06-01 00:00:00

abstract：:Imprinted genes are characterized by monoallelic expression that is dependent on parental origin. Comparative analysis of imprinted genes between species is a powerful tool for understanding the biological significance of genomic imprinting. The slc38a4 gene encodes a neutral amino acid transporter and is identified a...

journal_title：Biochemical genetics

authors： Xu D,Zhang C,Li J,Wang G,Chen W,Li D,Li S

更新日期：2018-12-01 00:00:00

abstract：:Because alternative RNA splicing regulation in the testis is prevalent, we explored testes of Sprague-Dawley rats for existence of alternatively spliced colony-stimulating factor 1 receptor (CSF-1R) mRNA. Using RT-PCR and sequencing, we identified a variant of CSF-1R mRNA that was 284 bp shorter than the full-length C...

journal_title：Biochemical genetics

authors： Su H,Wang Y,Söder O,Hou M

更新日期：2014-06-01 00:00:00

abstract：:The alpha-amylase in Drosophila melanogaster is a highly polymorphic enzyme, at both the allozyme level and the specific activity level. This enzyme changes its specific activity drastically depending on both food conditions and developmental stages, and it has been suggested that the ability to change its activity de...

journal_title：Biochemical genetics

authors： Yamate N,Yamazaki T

更新日期：1999-12-01 00:00:00

abstract：:The molecular weight forms of kynurenine formamidase were studied both gentically and biochemically. Formamidase I (native molecular weight 60,000) was purified using (NH4)2SO4 and pH fractionation, DEAE-cellulose chromatography at two different pH's, hydroxylapatite chromatography, and Sephadex G-100 gel filtration. ...

journal_title：Biochemical genetics

authors： Moore GP,Sullivan DT

更新日期：1978-08-01 00:00:00

abstract：:The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...

journal_title：Biochemical genetics

authors： Donald LJ,Wang HS,Hamerton JL

更新日期：1980-06-01 00:00:00

abstract：:The genetic differentiation among the populations of the European abalone Haliotis tuberculata was investigated using different markers to better understand the evolutionary history and exchanges between populations. Three markers were used: mitochondrial cytochrome oxidase I (COI), the sperm lysin nuclear gene, and e...

journal_title：Biochemical genetics

authors： Roussel V,Van Wormhoudt A

更新日期：2017-04-01 00:00:00

abstract：:The inducibility of alcohol dehydrogenase (ADH) has been recognized in different systems including maize, Drosophila, and mice. Our earlier results showed strain-specific ADH responses to chronic ethanol administration relative to matched littermate controls in mice. For this study we used two strains which showed "in...

journal_title：Biochemical genetics

authors： Wang CH,Singh SM

更新日期：1984-08-01 00:00:00

abstract：:A significant challenge in epistasis detection is the huge amount of data, which leads to combinatorial explosion. This study focuses on a two-stage approach for detecting epistasis only among single nucleotide polymorphisms (SNPs) that show some marginal effect. We present this two-stage approach based on the fusion ...

journal_title：Biochemical genetics

authors： Liao Z,Zeng Q,Liao B,Li X

更新日期：2014-10-01 00:00:00

abstract：:A slow-migrating beta-esterase (S-esterase) is described which has been detected in Drosophila montana, Drosophila imeretensis, and some stocks of Drosophila virilis when mixtures of alpha- and beta-naphthyl acetate are used as substrates in histochemical reactions after electrophoresis. Sexual dimorphism for S-estera...

journal_title：Biochemical genetics

authors： Korochkin LI,Belyaeva ES,Matveeva NM,Kuzin BA,Serov OL

更新日期：1976-02-01 00:00:00

abstract：:The X-linked immunodeficiency (Xid) in CBA/N mice serves as a model for the X-linked agammaglobulinemia (XLA) syndrome in man. X-chromosome inactivation in F1 heterozygotes derived from CBA/N (Xxid/Xxid) and B6.Pgk-1a (X+/Y) was investigated by monitoring the methylation status of the individual Pgk-1 alleles, Pgk-1b ...

journal_title：Biochemical genetics

authors： Shanmugam V,Chapman VM,Sell KW,Saha BK

更新日期：1996-02-01 00:00:00

abstract：:Panagrellus redivivus when placed in 7% ethanol or methanol becomes immobile. After 1 hr the animals resume normal swimming and will grow in alcohol. The ability to recover requires ADH activity and translation, but not transcription, as determined by inhibitor studies. Recovery decreases with longer-chain alcohols, w...

journal_title：Biochemical genetics

authors： Kriger F,Burke D,Samoiloff MR

更新日期：1977-12-01 00:00:00

abstract：:Salvia miltiorrhiza is a well-known medicinal plant and functional food in Asia. The range of quality among its germplasms is irregular, which inevitably affects its health and economic benefits. We established a system comprising phenotypic characteristics, ISSR markers, and active constituents to facilitate the comp...

journal_title：Biochemical genetics

authors： Zhang Y,Li X,Wang Z

更新日期：2013-10-01 00:00:00

abstract：:Using two-dimensional gel electrophoresis, we have analyzed proteins from a plasma membrane-enriched fraction from Phycomyces sporangiophores. Specifically, we have compared gels for night-blind mutants and a wild-type strain to find proteins involved in the early steps of the sensory transduction chain for phototropi...

journal_title：Biochemical genetics

authors： Pollock JA,Lipson ED,Sullivan DT

更新日期：1985-06-01 00:00:00

abstract：:Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine wheth...

journal_title：Biochemical genetics

authors： Fang L,Shen B,Irwin DM,Zhang S

更新日期：2014-10-01 00:00:00

abstract：:Genetic variation at three dipeptidase loci (Dip-A, Dip-B, and Dip-C) in Drosophila simulans was analyzed by starch gel electrophoresis. Dip-A was found to be polymorphic in four populations, while Dip-B and Dip-C were found to be polymorphic in one. The numbers of different alleles found at each respective locus were...

journal_title：Biochemical genetics

authors： Ohnishi S,Voelker RA

更新日期：1981-02-01 00:00:00

abstract：:Cleavage patterns of mitochondrial DNAs (mtDNAs) by 15 restriction endonucleases were analyzed for 10 swamp and 13 river types of domestic water buffaloes. Digestions with nine enzymes exhibited polymorphisms giving two or three kinds of cleavage patterns. Five mtDNA types were identified, three types in the swamp buf...

journal_title：Biochemical genetics

authors： Tanaka K,Yamagata T,Masangkay JS,Faruque MO,Vu-Binh D,Salundik,Mansjoer SS,Kawamoto Y,Namikawa T

更新日期：1995-06-01 00:00:00

abstract：:Gli-D1-encoded omega gliadins of bread wheats show little variation; their electrophoretic patterns can be classified into two main groups which broadly resemble the patterns found in the cultivars Chinese Spring and in Cheyenne. B and D subunits of low molecular weight glutenin encoded by the chromosome 1D loci Glu-D...

journal_title：Biochemical genetics

authors： Masci S,Porceddu E,Lafiandra D

更新日期：1991-08-01 00:00:00