Abstract:
:Differences in Zn-induced levels of hepatic metallothionein (MT) in inbred strains of the mouse are described. Three low-producing strains, C57 BL/6, C57BL/10, and NIH, are identified, while C3H and CBA display the highest levels of hepatic MT following Zn treatment. These interstrain differences affect not only the level of MT protein, but also the amount of MT-bound Zn and the total hepatic Zn concentration. Both MT isoforms are equally affected. A similar interstrain difference following Cu treatment is present in C3H and C57BL/6. The origin of these interstrain differences is discussed.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Farr C,Hunt DMdoi
10.1007/BF02401801subject
Has Abstractpub_date
1989-04-01 00:00:00pages
199-217issue
3-4eissn
0006-2928issn
1573-4927journal_volume
27pub_type
杂志文章abstract::The soluble proteins of the normal and male-sterile stamenless-2 (sl-2/sl-2) mutant of tomato (Lycopersicon esculentum) grown in different temperatures were analyzed by one- and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The normal and mutant stamens had some common proteins, but certai...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00556214
更新日期:1987-10-01 00:00:00
abstract::An electrophoretical analysis of blood plasma proteins of eight Anser and two Branta species was performed. Ten polymorphic proteins in blood plasma pattern were distinguished and described: four prealbumin proteins, albumin, three postalbumin proteins, transferrin, and a single posttransferrin protein. Genus-specific...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00557950
更新日期:1995-04-01 00:00:00
abstract::The gliadin composition of 78 spring durum wheat varieties has been studied by one-dimensional (Al-lactate, pH 3.1) and two-dimensional (first dimension, Al-lactate, pH 3.1; second dimension, sodium dodecyl sulfate-polyacrylamide gel) electrophoresis. Analysis of hybrids has shown that all components of the alpha zone...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02395516
更新日期:1988-12-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484518
更新日期:1984-06-01 00:00:00
abstract::Glycogen synthase, which catalyzes the synthesis of glycogen, is especially important for Old World (Pteropodidae) and New World (Phyllostomidae) fruit bats that ingest high-carbohydrate diets. Glycogen synthase 1, encoded by the Gys1 gene, is the glycogen synthase isozyme that functions in muscles. To determine wheth...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9659-4
更新日期:2014-10-01 00:00:00
abstract::Fourteen myoglobins of known sequence were examined by isoelectric focusing with and without urea. The 14 sequences formed six distinct mobility classes on gels without urea and three classes on those with urea. For these proteins, isoelectric focusing provides no advantage over single, nonequilibrium, nondenaturing g...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00504335
更新日期:1986-08-01 00:00:00
abstract::Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-019-09929-x
更新日期:2019-10-01 00:00:00
abstract::The allele, genotype, and haplotype frequencies among 837 Polish Holstein-Friesian cattle were determined at two regulatory indel polymorphisms of the PRNP gene. Allele frequencies at the 23 bp indel promoter polymorphism were 0.622 (del) and 0.378 (ins), with 0.613 and 0.387 in sires and 0.633 and 0.366 in dams. Alle...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9408-2
更新日期:2011-06-01 00:00:00
abstract::Hippophae rhamnoides ssp. sinensis is endemic to China, and it is a dioecious, outcrossing plant. Although many studies have been undertaken mainly on its agricultural, nutritional, medical, and ornamental value, little is known about its population genetics. This study uses random amplified polymorphic DNA to investi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9025-2
更新日期:2006-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9649-6
更新日期:2014-06-01 00:00:00
abstract::The immunological cross-reactivity of heterogeneous acid phosphatase isozymes from different human tissues has been studied using monospecific antisera prepared against four homogeneous acid phosphatases. The enzyme characterized as tartrate-inhibitable, prostatic acid phosphatase is also found to be present in leukoc...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00504327
更新日期:1985-04-01 00:00:00
abstract::There are three major groups of domestic cattle in East and Southeast Asia: European cattle, Zebu cattle, and Bali cattle. Ten restriction enzymes were used to analyze restriction site variants in the mitochondrial DNA (mtDNA) in 178 individuals belonging to these three groups of cattle. The results indicate that each...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554558
更新日期:1995-02-01 00:00:00
abstract::Fifty-six sequences encoding the pina protein were characterized from three species or subspecies of einkorn wheat. These sequences contained 1,595 nucleotides, including 1,270 conserved sites, 21 single nucleotide polymorphisms (SNPs), and 16 indels. The average frequency of SNPs and indels was one out of 76.1 and 99...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9239-1
更新日期:2009-06-01 00:00:00
abstract::Techniques are presented to detect 23 isozyme loci in the long-lived perennial plant, ponderosa pine. Meiotically derived megagametophyte from seeds is used to examine directly the segregation of allelic variants. Approximately seven seeds were initially examined for 12 enzymes from each of 47 trees from ten stands th...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498965
更新日期:1979-04-01 00:00:00
abstract::Basal activity of submaxillary gland (SMG) renin is high in female mice that carry the Rnrs allele and is induced to higher levels by treatment with dihydrotestosterone (DHT). To determine whether the difference in basal activity between high (Rnrs/Rnrs) and low (Rnrb/Rnrb) strains is due to enhanced sensitivity of Rn...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484623
更新日期:1981-06-01 00:00:00
abstract::The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554549
更新日期:1987-06-01 00:00:00
abstract::Three new linkage groups of enzyme loci are described using Poeciliopsis monacha x P. viriosa-derived interspecific backcross hybrids. Comparison to known linkage groups of the confamilial genus Xiphophorus shows homology between Xiphophorus linkage group I and Poeciliopsis linkage group III, Xiphophorus linkage group...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554823
更新日期:1990-02-01 00:00:00
abstract::The variable numbers of tandem repeats (VNTR) locus D1S80, located on chromosome 1 (1p35-36), has a repeat unit 16 bp in length, and different numbers of these repeat units have been observed for populations of different origins and ethnicity. We used a molecular identification method based on capillary electrophoresi...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9250-6
更新日期:2009-08-01 00:00:00
abstract::Nicotiana rustica L. HZNH, a native Chinese tobacco germplasm, displays a hypersensitive response (HR) and systemic acquired resistance following infection with tobacco mosaic virus (TMV). A resistance gene, CN, cloned from HZNH plants, was homologous to the N and NH genes identified in other Nicotiana species. The CN...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9229-3
更新日期:2009-04-01 00:00:00
abstract::Two types of alleles exist in the human alcohol dehydrogenase-2 (ADH2) locus. The usual ADH12 allele is common in Caucasians, while the atypical ADH22 allele is predominant in Orientals. The ADH22 produces the beta 2 subunit, which is catalytically far more active than the beta 1 subunit produced by the ADH12 gene. Th...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02399419
更新日期:1988-08-01 00:00:00
abstract::Following starch gel electrophoresis and a modified staining method, three distinct groups of acid phosphatase isozymes (AP-1, AP-2, and AP-3) have been identified in scutellum extracts of different inbred maize lines. The AP-2 group includes three electrophoretic variants: a fast (F), an intermediate (I), and a slow ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00483996
更新日期:1981-08-01 00:00:00
abstract::A new variant of alcohol dehydrogenase (ADH 7lk) was found in a laboratory stock of Drosophila melanogaster. ADH in this stock had the same electrophoretic mobility as the F variant both on acrylamide and on agar. Activity levels were similar to the levels in F flies at temperature between 15 and 25 C. But while ADH F...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484929
更新日期:1975-10-01 00:00:00
abstract::Maternal embryo leucine zipper kinase (MELK) has a higher expression level in a variety of cancers and involved in progression of colorectal cancer. The MELK expression levels in colorectal cancer tissues and cells were detected by RT-qPCR. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and transwe...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09974-x
更新日期:2020-10-01 00:00:00
abstract::Different homozygous lines of similar genotype with respect to G6pd and 6Pgd were shown to have different enzyme activities for G6PD and 6PGD. Crosses between high and low lines suggested that there were modifying genes present on the autosomes, while others were probably located on the X chromosome. Allelic variation...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484587
更新日期:1980-08-01 00:00:00
abstract::We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484449
更新日期:1983-06-01 00:00:00
abstract::This study aims to compare the expression of P2X receptor subtype mRNA in different arterial tissues of rats. After the rats were sacrificed, the internal carotid, pulmonary, thoracic aorta, mesenteric and caudal arteries were dissected out. Then, the P2X receptor mRNA expression in different blood vessels was detecte...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09968-9
更新日期:2020-10-01 00:00:00
abstract::The solubilized proteins of liver and brain from mice of two inbred strains (C57BL/6J and DBA/2J) and their hybrids were subfractionated by heparin Sepharose (H-S) CL-6B affinity chromatography. The H-S binding and nonbinding proteins were separated by two-dimensional electrophoresis. The protein patterns obtained wer...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554529
更新日期:1986-12-01 00:00:00
abstract::The cryptic plasmid pGY1, which is harbored by a clinical isolate of Salmonella enterica serovar Paratyphi A, was identified in a 9-year-old girl with paratyphoid fever in 2005, and its DNA sequence was determined. It is 3592 bp in length and had a G+C content of 43.3%. Three ORFs were predicted that share low similar...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9216-0
更新日期:2009-04-01 00:00:00
abstract::This work examines the molecular evolution of a brain-expressed X-linked gene family in the mammalian genomes of human, chimp, macaque, mouse, rat, dog, and cow. The gene structures are well conserved across family members and among the mammals in that all five members have three exons with the first two exons untrans...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9148-8
更新日期:2008-06-01 00:00:00
abstract::Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9350-3
更新日期:2010-08-01 00:00:00