Abstract:
:Different homozygous lines of similar genotype with respect to G6pd and 6Pgd were shown to have different enzyme activities for G6PD and 6PGD. Crosses between high and low lines suggested that there were modifying genes present on the autosomes, while others were probably located on the X chromosome. Allelic variation within each electrophoretic class of G6pd and 6Pgd might, however, also have contributed to this variation. An experiment on adaptation to sodium octanoate demonstrated that in adapted flies selection for lower enzyme activity had occurred, which provided further evidence for the existence of genetic differences in activity. Furthermore, a strong positive correlation between the activities of G6PD and 6PGD was found for each genotype. Since no correlation was found between MDH and the two enzymes G6PD and 6PGD, it could be concluded that this correlation was probably rather specific for G6PD and 6PGD. Interaction between genotypes with respect to activity was also found. It was shown that the variation at 6Pgd influenced the activity of G6PD within a genotype. The data are discussed in relation to fitness differences presented in foregoing articles.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Bijlsma Rdoi
10.1007/BF00484587subject
Has Abstractpub_date
1980-08-01 00:00:00pages
699-715issue
7-8eissn
0006-2928issn
1573-4927journal_volume
18pub_type
杂志文章abstract::Propionyl-CoA carboxylase (PCC) is involved in the catabolism of branched chain amino acids, odd-numbered fatty acids, cholesterol, and other metabolites. PCC consists of two subunits, α and β, encoded by the PCCA and PCCB genes, respectively. Mutations in the PCCA or PCCB subunit gene may lead to propionic acidemia. ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-014-9657-6
更新日期:2014-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1001963319965
更新日期:2000-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1002797219182
更新日期:2001-02-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1018797429804
更新日期:1998-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485850
更新日期:1984-08-01 00:00:00
abstract::A partial paired gene of Drosophila willistoni containing the paired box and extended homeo box was amplified by PCR and the nucleotide sequence of 1141 bp was determined. Comparison of the paired genes in D. willistoni and D. melanogaster showed that the proportions of identical nucleotide sites in the coding region ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00570122
更新日期:1996-12-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498914
更新日期:1983-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02396062
更新日期:1989-12-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-015-9690-0
更新日期:2015-12-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1010278631535
更新日期:2001-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/b:bigi.0000007777.87407.1b
更新日期:2003-12-01 00:00:00
abstract::Larval serum protein-1 (LSP-1) and LSP-2 are the major proteins of Drosophila larval serum. The amount of LSP-1 synthesized is strictly proportional to the number of LSP-1 genes present within the range 1-10. The normal number in female flies is 6. Flies with extreme amounts of LSP-1 were, by our criteria, as fit as t...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499473
更新日期:1984-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502121
更新日期:1979-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09968-9
更新日期:2020-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10528-008-9164-8
更新日期:2008-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-006-9025-2
更新日期:2006-06-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-012-9546-9
更新日期:2013-02-01 00:00:00
abstract::Variations at three flight-related enzyme loci, delta-glycerophosphate dehydrogenase (delta-Gpdh), glucose-6-phosphate dehydrogenase (G6pd), and phosphoglucomutase (Pgm), of Epiphyas postvittana (Walker) moths were investigated using starch gel electrophoresis. Among the three enzyme loci, delta-Gpdh and G6pd were fou...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554142
更新日期:1991-08-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/b:bigi.0000039807.50393.30
更新日期:2004-10-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485129
更新日期:1976-12-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499290
更新日期:1984-02-01 00:00:00
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journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9153-y
更新日期:2008-06-01 00:00:00
abstract::The murine submandibular gland (SMG) produces a novel class of highly acidic salivary proteins encoded by one or more highly abundant mRNA transcripts. In inbred mice, these transcripts are encoded by members of a multigene family comprising approximately 8-12 homologues. Most, and probably all, of these homologues ar...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02396156
更新日期:1989-10-01 00:00:00
abstract::Genetic linkage maps are valuable tools for genetic, genomic, and crop breeding studies. Several genetic linkage maps were constructed for the olive (Olea europaea L.) genome, mainly using amplified fragment length polymorphisms (AFLPs) and simple sequence repeat (SSR) markers. However, AFLPs and SSR markers were not ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-016-9721-5
更新日期:2016-06-01 00:00:00
abstract::Using megagametophyte (maternal haploid) and embryo (diploid) tissues of incense-cedar seeds, the expression of one of three malate dehydrogenase (MDH) loci was found to be influenced by a second, unlinked, modifier locus. Whereas alleles of the affected structural locus are codominant, the modifier alleles show domin...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484435
更新日期:1983-06-01 00:00:00
abstract::The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important role...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9166-6
更新日期:2008-08-01 00:00:00
abstract::The quantitative and qualitative distributions of gangliosides were determined in the cerebrum, cerebellum, and brain stem of five inbred strains (C57BL/6J, DBA/2J, LG/J, C3H/HeJ, BALB/cJ) of mice at 21 days of age. Genetic differences were found among the strains for wet weight, absolute amount of gangliosides per re...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484473
更新日期:1979-02-01 00:00:00
abstract::Ubiquitin-specific protease 9, Y-linked (USP9Y), is a protein encoded by the Y chromosome. Its precise function in the cell is unknown, although a role in the regulation of protein turnover has been postulated. Nonetheless, mutations in this gene could result in the over- or under-abundance of proteins involved in the...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-007-9139-1
更新日期:2008-04-01 00:00:00
abstract::Histone H1 from erythrocytes of Japanese quail was resolved in a sodium dodecyl sulfate (SDS)-polyacrylamide gel into five fractions differing in apparent molecular weights. A polymorphism of histone H1.1, H1.2, and H1.3 bands was detected among quail individuals. While some birds possessed either a high (phenotype .3...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02399686
更新日期:1991-10-01 00:00:00
abstract::Techniques are presented to detect 23 isozyme loci in the long-lived perennial plant, ponderosa pine. Meiotically derived megagametophyte from seeds is used to examine directly the segregation of allelic variants. Approximately seven seeds were initially examined for 12 enzymes from each of 47 trees from ten stands th...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498965
更新日期:1979-04-01 00:00:00