Abstract：
:Using two-dimensional gel electrophoresis, we have analyzed proteins from a plasma membrane-enriched fraction from Phycomyces sporangiophores. Specifically, we have compared gels for night-blind mutants and a wild-type strain to find proteins involved in the early steps of the sensory transduction chain for phototropism. In the gels for a mutant affected in the gene madA, a protein spot [51 kilodaltons (kdal) and pI 6.35] appears that is absent from the wild-type and the other mad mutants. Mutants affect in either of two madB alleles lack a protein spot (57 kdal and pI 6.6) that is present in the wild-type and all other mad strains; this spot probably represents the madB gene product. In some madC mutants, two spots (59 kdal, pI 6.5, with a covalently linked flavin; and 50 kdal, pI 6.4) are absent; however, in other madC strains, one or both of these spots are present. These four protein spots that are altered in madA, madB, and madC mutants may represent component of the photoreceptor complex responsible for phototropism in Phycomyces.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Pollock JA,Lipson ED,Sullivan DTdoi
10.1007/BF00499081subject
Has Abstractpub_date
1985-06-01 00:00:00pages
379-90issue
5-6eissn
0006-2928issn
1573-4927journal_volume
23pub_type
杂志文章abstract：:An enzyme catalyzing the transfer of the glucosyl moiety of UDP-glucose to the 3-hydroxyl group of cyanidin has been demonstrated in petal extracts of Silene dioica mutants with cyanidin-3-O-glucoside in the petals. This transferase activity was also present in young rosette leaves and calyces of these plants. The hig...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484525
更新日期：1978-12-01 00:00:00
abstract：:An electrophoretical analysis of blood plasma proteins of eight Anser and two Branta species was performed. Ten polymorphic proteins in blood plasma pattern were distinguished and described: four prealbumin proteins, albumin, three postalbumin proteins, transferrin, and a single posttransferrin protein. Genus-specific...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00557950
更新日期：1995-04-01 00:00:00
abstract：:A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific antisera. The concentration of Hb-F-Malta-I was 0.002-0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%, compared to a rat...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00483988
更新日期：1977-10-01 00:00:00
abstract：:A new variant of hereditary hemolytic anemia in a family due to high adenosine triphosphate (ATP) is reported. The increase in ATP levels varied from 83 to 105% in the family members. Low 2,3-diphosphoglycerate levels and low 2,3-diphosphoglyceromutase activity were observed in three family members, with normal glucos...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00504264
更新日期：1981-10-01 00:00:00
abstract：:Allelic frequencies at five polymorphic loci were determined in seven European and six Afrotropical populations of Drosophila melanogaster. African populations, which may be considered as ancestral for the species, showed a greater genetic diversity as measured by the number of alleles found. Within each geographic gr...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00483971
更新日期：1982-08-01 00:00:00
abstract：:Genetic diversity and genetic structure within and among ten populations of Stephania yunnanensis H. S. Lo and three populations of S. epigaea H. S. Lo from Yunnan province were evaluated by direct amplification of length polymorphism (DALP) markers. Five primer groups were screened, and a total of 287 DNA fragments w...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-008-9146-x
更新日期：2008-04-01 00:00:00
abstract：:Species in the genus Oryza (Poaceae) contain 10 genomic types and are distributed in pan-tropics of the world. To explore phylogenetic relationships of Oryza species having the AA-genome, DNA sequences of the chloroplast trnL intron and trnL-trnF spacer, mitochondrial nad1 intron 2, and nuclear internal transcribed sp...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-006-9062-x
更新日期：2007-02-01 00:00:00
abstract：:Genetic variation at three dipeptidase loci (Dip-A, Dip-B, and Dip-C) in Drosophila simulans was analyzed by starch gel electrophoresis. Dip-A was found to be polymorphic in four populations, while Dip-B and Dip-C were found to be polymorphic in one. The numbers of different alleles found at each respective locus were...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00486138
更新日期：1981-02-01 00:00:00
abstract：:Two electrophoretic variants of adenine phosphoribosyltransferase (APRT) were identified in a population of wild mice (Mus musculus bactrianus). Breeding tests demonstrated that the APRT variants are under the control of two alleles at an autosomal locus designated Aprt. We have examined the linkage relationships betw...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00554357
更新日期：1987-08-01 00:00:00
abstract：:Among several autoimmune diseases, one of the main risk factors is the female gender, and much consideration has been given to the involvement of female hormones in their etiology. B-cell activating factor (BAFF) is a key factor in survival and maturation of B cells and is overexpressed in several autoimmune patients ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-016-9752-y
更新日期：2016-10-01 00:00:00
abstract：:The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important role...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-008-9166-6
更新日期：2008-08-01 00:00:00
abstract：:Electrophoretic variation is described for malic enzyme (ME) for the first time in brook trout (Salvelinus fontinalis). Since the quaternary structure of ME was not clear from examination of banding patterns in brook trout alone, ME phenotypes in rainbow trout (Salmo gairdneri)X brook trout hybrids as wel as in esoci...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00502121
更新日期：1979-08-01 00:00:00
abstract：:Fifty-six sequences encoding the pina protein were characterized from three species or subspecies of einkorn wheat. These sequences contained 1,595 nucleotides, including 1,270 conserved sites, 21 single nucleotide polymorphisms (SNPs), and 16 indels. The average frequency of SNPs and indels was one out of 76.1 and 99...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-009-9239-1
更新日期：2009-06-01 00:00:00
abstract：:Genetic variations affecting the course of depressive symptoms in patients with coronary artery disease (CAD) have not yet been well studied. Therefore, we set out to investigate whether distinct haplotypes of the two insertion/deletion polymorphisms in the serotonin-transporter-linked polymorphic region (5-HTTLPR) an...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-020-09967-w
更新日期：2020-08-01 00:00:00
abstract：:The frequency distributions of apolipoprotein C alleles in native Asian sheep (Bengal, Kagi, Lampuchhre, Vietnamese, Myanmar, Baruwal, Bhyanglung, Khalkhas, and Kuwait) were determined using a one-dimensional polyacrylamide gel isoelectric-focusing immunoblotting technique. Among these Asian sheep, the genetic locus c...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1023/a:1020781629510
更新日期：2002-12-01 00:00:00
abstract：:Myocardial infarction (MI) is common in India and the disease occurs at a relatively younger age. We wanted to look for association of Angiotensin I-converting enzyme (ACE) gene with MI in North East India. We also wanted to examine possible environmental interaction of ACE gene with established cardiovascular risk fa...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-015-9706-9
更新日期：2016-04-01 00:00:00
abstract：:This study aims to compare the expression of P2X receptor subtype mRNA in different arterial tissues of rats. After the rats were sacrificed, the internal carotid, pulmonary, thoracic aorta, mesenteric and caudal arteries were dissected out. Then, the P2X receptor mRNA expression in different blood vessels was detecte...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-020-09968-9
更新日期：2020-10-01 00:00:00
abstract：:This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SNPs (rs4536, rs4545, rs3097, and rs3802230) and the K173R polymorphism...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-010-9393-5
更新日期：2011-02-01 00:00:00
abstract：:Maternal embryo leucine zipper kinase (MELK) has a higher expression level in a variety of cancers and involved in progression of colorectal cancer. The MELK expression levels in colorectal cancer tissues and cells were detected by RT-qPCR. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and transwe...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-020-09974-x
更新日期：2020-10-01 00:00:00
abstract：:Three dipeptidases in Drosophila melanogaster are under independent genetic control and their structural genes have been localized, Dip-A to 2R and Dip-B and Dip-C to 3R (Voelker and Langley, 1978; Ohnishi and Voelker, 1981). These enzymes were characterized with respect to their substrate specificities, genetic varia...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484692
更新日期：1982-06-01 00:00:00
abstract：:We have shown in our previous work that in the tetraploid loach Misgurnus fossilis carboxylesterase-2 (E-2) phenotypes of embryos and early larvae are controlled by the alleles of the Est-2 locus. In the present work it has been established that the somatic tissues of many adult fish homozygous for one of the Est-2 al...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484449
更新日期：1983-06-01 00:00:00
abstract：:Suspicious hybrids of painted storks and milky storks were found in a Malaysian zoo. Blood of these birds was sampled on FTA cards for DNA fingerprinting. Of 44 optimized primers, 6 produced diagnostic markers that could identify hybrids. The markers were based on simple, direct PCR-generated multilocus banding patter...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-013-9607-8
更新日期：2013-10-01 00:00:00
abstract：:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) exhibit genetic polymorphism and tissue specificity. ADH and ALDH isozyme phenotypes from 39 surgical Chinese lung specimens were identified by agarose isoelectric focusing. The identity of the lung beta-ADHs was further demonstrated by their characteristic...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF02399709
更新日期：1992-04-01 00:00:00
abstract：:Because alternative RNA splicing regulation in the testis is prevalent, we explored testes of Sprague-Dawley rats for existence of alternatively spliced colony-stimulating factor 1 receptor (CSF-1R) mRNA. Using RT-PCR and sequencing, we identified a variant of CSF-1R mRNA that was 284 bp shorter than the full-length C...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-014-9649-6
更新日期：2014-06-01 00:00:00
abstract：:Three distinct malathion carboxylesterase (MCE) phenotypes have been identified among strains of Lucilia cuprina. The high-activity phenotype shows 1.6- and 33-fold more MCE specific activity than the intermediate- and low-activity phenotypes, respectively. Flies with high MCE activity are 1000-fold more resistant to ...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00566064
更新日期：1994-12-01 00:00:00
abstract：:The East Himalaya-Hengduan Mountains region is the center of diversity of the genus Primula, and P. sikkimensis is one of the most common members of the genus in the region. In this study, the genetic diversity and structure of P. sikkimensis populations in China were assessed using inter-simple sequence repeat (ISSR)...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-007-9131-9
更新日期：2008-02-01 00:00:00
abstract：:To determine the prevalence of G6PD deficiency and a Mediterranean mutation among males in southeastern Iran, we studied 1,097 Sistani and Balouch schoolboys. A questionnaire was used to collect demographic data and a history of malaria infection; blood samples were evaluated for G6PD deficiency and the G6PD Mediterra...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-012-9548-7
更新日期：2013-02-01 00:00:00
abstract：:DNA damage repair elements accumulate at DNA damage sites to form ionizing radiation-induced foci (IRIF) for damage repair. IRIF, which represent direct evidence of DNA damage response activity, which are conveniently to be observed via immunofluorescence staining. Protein ubiquitination plays an important role in ini...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/s10528-015-9707-8
更新日期：2016-04-01 00:00:00
abstract：:The primary structures of the alpha globins from CE/J, DBA/2J, and a stock of Potter's mice were determined to identify the amino acid substitutions associated with the unique isoelectric focusing patterns of these hemoglobins. In addition, the primary structures of the alpha globins from MOL III and PERU mice were st...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF00484946
更新日期：1982-02-01 00:00:00
abstract：:Genetic variation of a codominantly inherited pancreas protease, designated CTRA-1, was discovered in the house mouse by isoelectric focusing in polyacrylamide gels. Phenotype CTRA-1A was found in MOLH/Fre and in the majority of common laboratory mouse strains. Phenotype CTRA-1B was found in PWD/Ph. It was characteriz...
journal_title：Biochemical genetics
pub_type： 杂志文章
doi：10.1007/BF02426870
更新日期：1991-12-01 00:00:00
