Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: implications for ethanol metabolism and cytotoxicity.

abstract：:Akt isoforms have critical roles in the cause and regulation of cancer cells invasive, migration, and metastatic dissemination. In the present study, the association between Akt1 polymorphisms and endometrial cancer was investigated in patients with endometrial cancer and controls. Thirty premenopaused patients diagno...

journal_title：Biochemical genetics

authors： Fallah S,Korani M,Hajimirza M,Seifi M

更新日期：2015-12-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) have a high prevalence in humans in the past two decades. Here, we elucidated the functions of miR-30a-3p in the development of NAFLD and identified its potential targets. HepG-2 cells and NAFLD patients' blood samples were used in our study. Bioinformatics analysis as well as...

journal_title：Biochemical genetics

authors： Wang DR,Wang B,Yang M,Liu ZL,Sun J,Wang Y,Sun H,Xie LJ

更新日期：2020-10-01 00:00:00

abstract：:Gli-D1-encoded omega gliadins of bread wheats show little variation; their electrophoretic patterns can be classified into two main groups which broadly resemble the patterns found in the cultivars Chinese Spring and in Cheyenne. B and D subunits of low molecular weight glutenin encoded by the chromosome 1D loci Glu-D...

journal_title：Biochemical genetics

authors： Masci S,Porceddu E,Lafiandra D

更新日期：1991-08-01 00:00:00

abstract：:ZFY-like genes have been observed in a variety of vertebrate species. Although originally implicated as the primary testis-determining gene in humans and other placental mammals, more recent evidence indicates a role(s) outside that of testis determination. In this study, DNA from five species of fish, Carasius auratu...

journal_title：Biochemical genetics

authors： Zimmerer EJ,Threlkeld L

更新日期：1995-08-01 00:00:00

abstract：:The locus for sorbitol dehydrogenase (SORD, E.C. 1.1.1.14) has been shown to segregate with hexosaminidase A and mannose phosphate isomerase in a series of human-Chinese hamster somatic cell hybrids. Cytogenetic analysis supports the assignment to chromosome 15 and further defines the gene locus to the region 15pter l...

journal_title：Biochemical genetics

authors： Donald LJ,Wang HS,Hamerton JL

更新日期：1980-06-01 00:00:00

abstract：:Active-site tryptic peptides were isolated from three genetic types of human serum cholinesterase. The active-site peptide was identified by labeling the active-site serine with [3H]diisopropylfluorophosphate. Peptides were purified by high-performance liquid chromatography. Amino acid composition and sequence analysi...

journal_title：Biochemical genetics

authors： Lockridge O,La Du BN

更新日期：1986-06-01 00:00:00

abstract：:Restriction endonuclease analyses of DNA from one Black G gamma A gamma-HPFH homozygote and four Black and one Indian G gamma A gamma-HPFH heterozygotes have identified three different HPFH types which are the result of large deletions including the delta and beta genes. Two of the types are comparable to those charac...

journal_title：Biochemical genetics

authors： Kutlar A,Gardiner MB,Headlee MG,Reese AL,Cleek MP,Nagle S,Sukumaran PK,Huisman TH

更新日期：1984-02-01 00:00:00

abstract：:A survey of laboratory strains of Anopheles stephensi for nonspecific esterases by polyacrylamide gel electrophoresis revealed 10 zones of esterase activity. In 3 of the 10 zones, three electromorphs were observed. Genetic analysis revealed that these three zones are controlled by three loci, viz., Est-3, Est-4, and E...

journal_title：Biochemical genetics

authors： Adak T,Subbarao SK,Sharma VP

更新日期：1984-06-01 00:00:00

abstract：:Polymorphic esterase and acetylcholinesterase alleles in the whitefly Bemisia tabaci were studied using electrophoretic and colorimetric assays. The segregation of these alleles between parental and F1 generations provided unequivocal evidence of haplodiploidy in this pest species. Unmated females, heterozygous at a p...

journal_title：Biochemical genetics

authors： Byrne FJ,Devonshire AL

更新日期：1996-04-01 00:00:00

abstract：:Male and female wild Norway rats (Rattus norvegicus Erxleben) and male and female albino outbred rats (Ipf:RIZ) were crossbred. These animals were the control, noninbred group (0% inbred). By systematic full-sib mating, two experimental groups (50 and 91% of inbred) were raised. Half of each group (both males and fema...

journal_title：Biochemical genetics

authors： Kosowska B

更新日期：1992-08-01 00:00:00

abstract：:The primary structures of the alpha globins from CE/J, DBA/2J, and a stock of Potter's mice were determined to identify the amino acid substitutions associated with the unique isoelectric focusing patterns of these hemoglobins. In addition, the primary structures of the alpha globins from MOL III and PERU mice were st...

journal_title：Biochemical genetics

authors： Popp RA,Bailiff EG,Skow LC,Whitney JB 3rd

更新日期：1982-02-01 00:00:00

abstract：:The retinal pigment epithelium (RPE) plays a key role in the maintenance of the normal functions of the retina. Tissue engineering using amniotic membrane as a substrate to culture RPE cells may provide a promising new strategy to replace damaged RPE. We established a method of culturing RPE cells over the amniotic me...

journal_title：Biochemical genetics

authors： Akrami H,Soheili ZS,Sadeghizadeh M,Khalooghi K,Ahmadieh H,Kanavi MR,Samiei S,Pakravesh J

更新日期：2011-06-01 00:00:00

abstract：:A slow-migrating beta-esterase (S-esterase) is described which has been detected in Drosophila montana, Drosophila imeretensis, and some stocks of Drosophila virilis when mixtures of alpha- and beta-naphthyl acetate are used as substrates in histochemical reactions after electrophoresis. Sexual dimorphism for S-estera...

journal_title：Biochemical genetics

authors： Korochkin LI,Belyaeva ES,Matveeva NM,Kuzin BA,Serov OL

更新日期：1976-02-01 00:00:00

abstract：:Isoenzyme electrophoresis was used as a method to determine genetic diversity in various M. esculenta cultivars collected in the Southwestern (SW) and Northwestern (NW) regions of the State of Parana, in the South region of Brazil, and in cultivars produced at the Agronomic Institute of Campinas (IAC), São Paulo State...

journal_title：Biochemical genetics

authors： Resende AG,Vidigal Filho P,Machado MF

更新日期：2000-08-01 00:00:00

abstract：:The microRNAs (miRNAs) are involved in multiple pathological processes among various types of tumors. However, the functions of miRNAs in benign brain tumors are largely unexplored. In order to explore the pathogenesis of the invasiveness in non-functional pituitary adenoma (NFPA), the miRNAs expression profile was an...

journal_title：Biochemical genetics

authors： Wu S,Gu Y,Huang Y,Wong TC,Ding H,Liu T,Zhang Y,Zhang X

更新日期：2017-06-01 00:00:00

abstract：:Patterns of lactate dehydrogenase (LDH) isozymes of tissues from various mouse strains were examined. An interstrain polymorphism for LDH isozymes of liver was established. One phenotype (CBA/Lac and AKR/J mice) yielded a five-banded LDH pattern, another phenotype (DBA/1J, DBA/2J, C57BL/6J and C3H/He) showed a three-b...

journal_title：Biochemical genetics

authors： Khlebodarova TM,Serov OL

更新日期：1980-10-01 00:00:00

abstract：:The acidic proline-rich proteins (Pr) showing genetic polymorphism were purified from human parotid salivas by gel filtration and ion exchange chromatography. Molecular weight determinations, amino acid composition analyses, and polypeptide mapping experiments indicate that the Pr 3 protein is a fragment of the Pr 1 p...

journal_title：Biochemical genetics

authors： Karn RC,Friedman RD,Merritt AD

更新日期：1979-12-01 00:00:00

abstract：:There are three major groups of domestic cattle in East and Southeast Asia: European cattle, Zebu cattle, and Bali cattle. Ten restriction enzymes were used to analyze restriction site variants in the mitochondrial DNA (mtDNA) in 178 individuals belonging to these three groups of cattle. The results indicate that each...

journal_title：Biochemical genetics

authors： Kikkawa Y,Amano T,Suzuki H

更新日期：1995-02-01 00:00:00

abstract：:The molecular nature of chicken fetal antigen (CFA) and quail fetal antigen (QFA) was studied on embryonic red blood cells (RBCs) of the chicken, the Japanese quail, and the quail-chicken hybrid. Specific immunoprecipitation of radiolabeled membrane proteins followed by electrophoretic separation and autoradiography w...

journal_title：Biochemical genetics

authors： Dietert RR,Hartwell DP,Kline K,Sanders BG

更新日期：1984-10-01 00:00:00

abstract：:The gliadin composition of 78 spring durum wheat varieties has been studied by one-dimensional (Al-lactate, pH 3.1) and two-dimensional (first dimension, Al-lactate, pH 3.1; second dimension, sodium dodecyl sulfate-polyacrylamide gel) electrophoresis. Analysis of hybrids has shown that all components of the alpha zone...

journal_title：Biochemical genetics

authors： Kudryavtsev AM,Metakovsky EV,Sozinov AA

更新日期：1988-12-01 00:00:00

abstract：:The single-strand conformation polymorphism (SSCP) procedure has been applied in routine testing for hereditary diseases. Temperature, running buffer, gel composition, and fragment length can influence its sensitivity. Mutation detection in the clinical setting depends on the development of automated technology, espec...

journal_title：Biochemical genetics

authors： Okamoto Y,Ueta A,Sumi S,Ito T,Okubo Y,Jose Y,Ninomiya A,Togari H,Nishida M

更新日期：2007-10-01 00:00:00

abstract：:Random amplified polymorphic DNA was used to assess the level of genetic diversity and genetic structure of Stipa krylovii (Gramineae), an important dominant species in the northern grasslands of China. Genetic diversity was low within S. krylovii populations, and diversity at the population level was associated with ...

journal_title：Biochemical genetics

authors： Zhao NX,Gao YB,Wang JL,Ren AZ

更新日期：2006-12-01 00:00:00

abstract：:In corn seedlings (Zea mays L.) homozygous for the mutation gl5, the surface waxes are characteristically altered. In this mutant the main wax constituents (83.5%) are aldehydes while in the normal waxes alcohols predominate (62.7%). Moreover, in the normal waxes aldehydes and alcohols are made up mainly of the C32 te...

journal_title：Biochemical genetics

authors： Bianchi G,Avato P,Salamini F

更新日期：1978-10-01 00:00:00

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:The genetic divergence, population genetic structure, and possible speciation of the Korean firefly, Pyrocoelia rufa, were investigated on the midsouthern Korean mainland, coastal islets, a remote offshore island, Jedu-do, and Tsushima Island in Japan. Analysis of DNA sequences from the mitochondrial COI protein-codin...

journal_title：Biochemical genetics

authors： Lee SC,Bae JS,Kim I,Suzuki H,Kim SR,Kim JG,Kim KY,Yang WJ,Lee SM,Sohn HD,Jin BR

更新日期：2003-12-01 00:00:00

abstract：:Malate dehydrogenase (MDH; EC 1.1.1.37) isozymes in long-term callus tissue culture of Cereus peruvianus were studied in starch gel electrophoresis to investigate the control of differential Mdh gene expression under sugar and temperature stress. While two cytosol MDH isozymes showed an unchanged phenotype when the ca...

journal_title：Biochemical genetics

authors： Jorge IC,Mangolin CA,Machado MF

更新日期：1997-06-01 00:00:00

abstract：:beta-Glucuronidase (GUS) has become an important enzyme model for the genetic study of molecular disease, enzyme realization, and therapy, and for the biogenesis and function of the lysosome and lysosomal enzymes. The genetics of human beta-glucuronidase was investigated utilizing 188 primary man-mouse and man-chinese...

journal_title：Biochemical genetics

authors： Lalley PA,Brown JA,Eddy RL,Haley LL,Byers MG,Goggin AP,Shows TB

更新日期：1977-04-01 00:00:00

abstract：:In Neurospora crassa, the expression of unlinked structural genes which encode nitrogen catabolic enzymes is subject to genetic and metabolic regulation. The negative-acting nmr regulatory gene appears to play a role in nitrogen catabolite repression. Using the N. crassa nmr gene as a probe, homologous sequences were ...

journal_title：Biochemical genetics

authors： Young JL,Marzluf GA

更新日期：1991-10-01 00:00:00

abstract：:Prolamin mixtures were isolated from oats, rice, normal and high-lysine sorghum, two varieties of pearl millet, two strains of teosinte, and gamma grass and subjected to NH2-terminal amino acid sequence determinations. In each case (except for rice, whose prolamins apparently have blocked or unavailable NH2-terminal r...

journal_title：Biochemical genetics

authors： Bietz JA

更新日期：1982-12-01 00:00:00

abstract：:Two complementing loci in different linkage groups of the basidiomycete Ustilago violacea are involved in urease activity: a structural one (ure-1) and a second inferred to involve a permease (ure-2) locus. Two types of complementing mutations occur in the structural locus: null activity (ure-la) and obviously reduced...

journal_title：Biochemical genetics

authors： Baird ML,Garber ED

更新日期：1981-12-01 00:00:00