Cloning, expression, and genomic structure of a novel human Rap2 interacting gene (RPIP9).

Abstract:

:During a large-scale screen of a human fetal brain cDNA library, a full-length cDNA encoding a novel Rap2 interacting protein was isolated and sequenced. The cDNA is 3397bp long and has a predicted open reading frame encoding a protein of 329 aa. The predicted protein shows high homology to mouse and human RPIP8, and has a RUN domain near its C-terminus. The gene was mapped to human chromosome 7q21-7q22 and has 9 exons and 8 introns. The expression pattern was also detected by cycle-limited reverse polymerase chain reaction (RT-PCR).

journal_name

Biochem Genet

journal_title

Biochemical genetics

authors

Wang S,Zhang Z,Ying K,Chen JZ,Meng XF,Yang QS,Xie Y,Mao YM

doi

10.1023/a:1020918411532

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

13-25

issue

1-2

eissn

0006-2928

issn

1573-4927

journal_volume

41

pub_type

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