Attempted isolation of viruses from myasthenia gravis thymus.

Abstract:

:A systematic study of thymus homogenates and cell suspensions from 13 patients with myasthenia gravis (MG) of recent onset, and 6 non-myasthenic controls, has failed to detect or isolate virus by cell culture with 'rescue techniques', electron microscopy, or intracerebral inoculation into neonatal mice. These results do not support the case for persistent viral infection in the thymus, and impose constraints on hypotheses of a viral aetiology of MG.

journal_name

J Neuroimmunol

authors

Klavinskis LS,Willcox HN,Richmond JE,Newsom-Davis J

doi

10.1016/0165-5728(86)90082-2

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

287-99

issue

4

eissn

0165-5728

issn

1872-8421

pii

0165-5728(86)90082-2

journal_volume

11

pub_type

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