Author Correction: Functional organization and population dynamics in the mouse primary auditory cortex.

abstract：:Sensorimotor integration is crucial to perception and motor control. How and where this process takes place in the brain is still largely unknown. Here we analyze the cerebellar contribution to sensorimotor integration in the whisker system of mice. We identify an area in the cerebellum where cortical sensory and moto...

journal_title：Nature neuroscience

authors： Proville RD,Spolidoro M,Guyon N,Dugué GP,Selimi F,Isope P,Popa D,Léna C

更新日期：2014-09-01 00:00:00

abstract：:It is widely believed that attention selects locations at an earlier stage than it selects nonspatial features, but this has been tested only under conditions of minimal competition. We found that, when competition was increased, color-based attention was able to influence the feedforward flow of information in humans...

journal_title：Nature neuroscience

authors： Zhang W,Luck SJ

更新日期：2009-01-01 00:00:00

abstract：:The molecular mechanisms that activate morphogenesis of cerebral cortex are currently the subject of intensive experimental analysis. Transcription factor genes of the homeobox, basic helix-loop-helix (bHLH) and zinc-finger families have recently been shown to have essential roles in this process. However, the actual ...

journal_title：Nature neuroscience

authors： Muzio L,Di Benedetto B,Stoykova A,Boncinelli E,Gruss P,Mallamaci A

更新日期：2002-08-01 00:00:00

abstract：:The orbitofrontal cortex plays a central role in good-based economic decisions. When subjects make choices, neurons in this region represent the identities and values of offered and chosen goods. Notably, choices in different behavioral contexts may involve a potentially infinite variety of goods. Thus a fundamental q...

journal_title：Nature neuroscience

authors： Xie J,Padoa-Schioppa C

更新日期：2016-06-01 00:00:00

abstract：:Recent imaging studies show that the formation of neural connections in the central nervous system is a highly dynamic process. The iterative formation and elimination of synapses and neuronal branches result in the formation of a much larger number of trial connections than is maintained in the mature brain. Neural a...

journal_title：Nature neuroscience

authors： Hua JY,Smith SJ

更新日期：2004-04-01 00:00:00

abstract：:Phagocytic cell NADPH oxidase (NOX) generates reactive oxygen species (ROS) as part of innate immunity. Unfortunately, ischemia can also induce this pathway and inflict damage on native cells. The voltage-gated proton channel Hv1 enables NOX function by compensating cellular loss of electrons with protons. Accordingly...

journal_title：Nature neuroscience

authors： Wu LJ,Wu G,Akhavan Sharif MR,Baker A,Jia Y,Fahey FH,Luo HR,Feener EP,Clapham DE

更新日期：2012-03-04 00:00:00

abstract：:In the postnatal subventricular zone (SVZ), local cues or signaling molecules released from neuroblasts limit the proliferation of glial fibrillary acidic protein (GFAP)-expressing progenitors thought to be stem cells. However, signals between SVZ cells have not been identified. We show that depolarization of neurobla...

journal_title：Nature neuroscience

authors： Liu X,Wang Q,Haydar TF,Bordey A

更新日期：2005-09-01 00:00:00

abstract：:Mammalian sterile 20-like kinase-3b (Mst3b, encoded by Stk24), regulates axon outgrowth in embryonic cortical neurons in culture, but its role in vivo and in neural repair is unknown. Here we show that Mst3b mediates the axon-promoting effects of trophic factors in mature rat retinal ganglion cells (RGCs) and dorsal r...

journal_title：Nature neuroscience

authors： Lorber B,Howe ML,Benowitz LI,Irwin N

更新日期：2009-11-01 00:00:00

abstract：:Many of the behavioral consequences of stress are mediated by the activation of the glucocorticoid receptor by stress-induced high levels of glucocorticoid hormones. To explore the molecular mechanisms of these effects, we combined in vivo and in vitro approaches. We analyzed mice carrying a brain-specific mutation (G...

journal_title：Nature neuroscience

authors： Revest JM,Di Blasi F,Kitchener P,Rougé-Pont F,Desmedt A,Turiault M,Tronche F,Piazza PV

更新日期：2005-05-01 00:00:00

abstract：:The diseased brain hosts a heterogeneous population of myeloid cells, including parenchymal microglia, perivascular cells, meningeal macrophages and blood-borne monocytes. To date, the different types of brain myeloid cells have been discriminated solely on the basis of their localization, morphology and surface epito...

journal_title：Nature neuroscience

authors： Prinz M,Priller J,Sisodia SS,Ransohoff RM

更新日期：2011-09-27 00:00:00

abstract：:All the higher mental and cognitive functions unique to humans depend on the neocortex ('new' cortex, referring to its relatively recent appearance in evolution), which is divided into discrete areas that subserve distinct functions, such as language, movement and sensation. With a few notable exceptions, all neocorti...

journal_title：Nature neuroscience

authors： Monuki ES,Walsh CA

更新日期：2001-11-01 00:00:00

abstract：:Orchestrating appropriate behavioral responses in the face of competing signals that predict either rewards or threats in the environment is crucial for survival. The basolateral nucleus of the amygdala (BLA) and prelimbic (PL) medial prefrontal cortex have been implicated in reward-seeking and fear-related responses,...

journal_title：Nature neuroscience

authors： Burgos-Robles A,Kimchi EY,Izadmehr EM,Porzenheim MJ,Ramos-Guasp WA,Nieh EH,Felix-Ortiz AC,Namburi P,Leppla CA,Presbrey KN,Anandalingam KK,Pagan-Rivera PA,Anahtar M,Beyeler A,Tye KM

更新日期：2017-06-01 00:00:00

abstract：:A moving grating elicits innate optomotor behavior in zebrafish larvae; they swim in the direction of perceived motion. We took advantage of this behavior, using computer-animated displays, to determine what attributes of motion are extracted by the fish visual system. As in humans, first-order (luminance-defined or F...

journal_title：Nature neuroscience

authors： Orger MB,Smear MC,Anstis SM,Baier H

更新日期：2000-11-01 00:00:00

abstract：:Newborn microglia rapidly replenish the whole brain after selective elimination of most microglia (>99%) in adult mice. Previous studies reported that repopulated microglia were largely derived from microglial progenitor cells expressing nestin in the brain. However, the origin of these repopulated microglia has been ...

journal_title：Nature neuroscience

authors： Huang Y,Xu Z,Xiong S,Sun F,Qin G,Hu G,Wang J,Zhao L,Liang YX,Wu T,Lu Z,Humayun MS,So KF,Pan Y,Li N,Yuan TF,Rao Y,Peng B

更新日期：2018-04-01 00:00:00

abstract：:Cell type-specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of four knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTomato and ChR2-EYFP, halorhodopsin eNpHR3.0 and archaerhodopsi...

journal_title：Nature neuroscience

authors： Madisen L,Mao T,Koch H,Zhuo JM,Berenyi A,Fujisawa S,Hsu YW,Garcia AJ 3rd,Gu X,Zanella S,Kidney J,Gu H,Mao Y,Hooks BM,Boyden ES,Buzsáki G,Ramirez JM,Jones AR,Svoboda K,Han X,Turner EE,Zeng H

更新日期：2012-03-25 00:00:00

abstract：:Accurate optical reporting of electrical activity in genetically defined neuronal populations is a long-standing goal in neuroscience. We developed Accelerated Sensor of Action Potentials 1 (ASAP1), a voltage sensor design in which a circularly permuted green fluorescent protein is inserted in an extracellular loop of...

journal_title：Nature neuroscience

authors： St-Pierre F,Marshall JD,Yang Y,Gong Y,Schnitzer MJ,Lin MZ

更新日期：2014-06-01 00:00:00

abstract：:The ventral intraparietal area (VIP) receives converging inputs from visual, somatosensory, auditory and vestibular systems that use diverse reference frames to encode sensory information. A key issue is how VIP combines those inputs together. We mapped the visual and tactile receptive fields of multimodal VIP neurons...

journal_title：Nature neuroscience

authors： Avillac M,Denève S,Olivier E,Pouget A,Duhamel JR

更新日期：2005-07-01 00:00:00

abstract：:It is widely held that color and motion are processed by separate parallel pathways in the visual system, but this view is difficult to reconcile with the fact that motion can be detected in equiluminant stimuli that are defined by color alone. To examine the relationship between color and motion, we tested three pati...

journal_title：Nature neuroscience

authors： Cavanagh P,Hénaff MA,Michel F,Landis T,Troscianko T,Intriligator J

更新日期：1998-07-01 00:00:00

abstract：:Precise apposition of pre- to postsynaptic specializations is required for optimal function of chemical synapses, but little is known about how it is achieved. At the skeletal neuromuscular junction, active zones (transmitter release sites) in the nerve terminal lie directly opposite junctional folds in the postsynapt...

journal_title：Nature neuroscience

authors： Patton BL,Cunningham JM,Thyboll J,Kortesmaa J,Westerblad H,Edström L,Tryggvason K,Sanes JR

更新日期：2001-06-01 00:00:00

abstract：:The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system. After release into the synaptic cleft, ACh is rapidly degraded by acetylcholinesterase (AChE). We have identified a mutation in the ache gene of the zebrafish, which abolishes ACh hydrolysis in ...

journal_title：Nature neuroscience

authors： Behra M,Cousin X,Bertrand C,Vonesch JL,Biellmann D,Chatonnet A,Strähle U

更新日期：2002-02-01 00:00:00

abstract：:In this Perspective, we expand the notion of temporal regulation of RNA in the brain and propose that the qualitative nature of RNA and its metabolism, together with RNA abundance, are essential for the molecular mechanisms underlying experience-dependent plasticity. We discuss emerging concepts in the newly burgeonin...

journal_title：Nature neuroscience

authors： Nainar S,Marshall PR,Tyler CR,Spitale RC,Bredy TW

更新日期：2016-09-27 00:00:00

abstract：:Specialization and hierarchy are organizing principles for primate cortex, yet there is little direct evidence for how cortical areas are specialized in the temporal domain. We measured timescales of intrinsic fluctuations in spiking activity across areas and found a hierarchical ordering, with sensory and prefrontal ...

journal_title：Nature neuroscience

authors： Murray JD,Bernacchia A,Freedman DJ,Romo R,Wallis JD,Cai X,Padoa-Schioppa C,Pasternak T,Seo H,Lee D,Wang XJ

更新日期：2014-12-01 00:00:00

abstract：:Tumor-associated macrophages (TAMs) play an important role in the immune response to cancer, but the mechanisms by which the tumor microenvironment controls TAMs and T cell immunity are not completely understood. Here we report that kynurenine produced by glioblastoma cells activates aryl hydrocarbon receptor (AHR) in...

journal_title：Nature neuroscience

authors： Takenaka MC,Gabriely G,Rothhammer V,Mascanfroni ID,Wheeler MA,Chao CC,Gutiérrez-Vázquez C,Kenison J,Tjon EC,Barroso A,Vandeventer T,de Lima KA,Rothweiler S,Mayo L,Ghannam S,Zandee S,Healy L,Sherr D,Farez MF,Prat A,

更新日期：2019-05-01 00:00:00

abstract：:The healthy human brain is a mosaic of varied genomes. Long interspersed element-1 (LINE-1 or L1) retrotransposition is known to create mosaicism by inserting L1 sequences into new locations of somatic cell genomes. Using a machine learning-based, single-cell sequencing approach, we discovered that somatic L1-associat...

journal_title：Nature neuroscience

authors： Erwin JA,Paquola AC,Singer T,Gallina I,Novotny M,Quayle C,Bedrosian TA,Alves FI,Butcher CR,Herdy JR,Sarkar A,Lasken RS,Muotri AR,Gage FH

更新日期：2016-12-01 00:00:00

abstract：:We show that a natural behavior, exploration of a novel environment, causes DNA double-strand breaks (DSBs) in neurons of young adult wild-type mice. DSBs occurred in multiple brain regions, were most abundant in the dentate gyrus, which is involved in learning and memory, and were repaired within 24 h. Increasing neu...

journal_title：Nature neuroscience

authors： Suberbielle E,Sanchez PE,Kravitz AV,Wang X,Ho K,Eilertson K,Devidze N,Kreitzer AC,Mucke L

更新日期：2013-05-01 00:00:00

abstract：:Synaptic stimulation activates signal transduction pathways, producing persistently active protein kinases. PKMzeta is a truncated, persistently active isoform of atypical protein kinase C-zeta (aPKCzeta), which lacks the N-terminal pseudosubstrate regulatory domain. Using a Pavlovian olfactory learning task in Drosop...

journal_title：Nature neuroscience

authors： Drier EA,Tello MK,Cowan M,Wu P,Blace N,Sacktor TC,Yin JC

更新日期：2002-04-01 00:00:00

abstract：:Shared neural variability is ubiquitous in cortical populations. While this variability is presumed to arise from overlapping synaptic input, its precise relationship to local circuit architecture remains unclear. We combine computational models and in vivo recordings to study the relationship between the spatial stru...

journal_title：Nature neuroscience

authors： Rosenbaum R,Smith MA,Kohn A,Rubin JE,Doiron B

更新日期：2017-01-01 00:00:00

abstract：:Neurotransmitter transporters can affect neuronal excitability indirectly via modulation of neurotransmitter concentrations or directly via transporter currents. A physiological or pathophysiological role for transporter currents has not been described. We found that GABA transporter 1 (GAT-1) cation currents directly...

journal_title：Nature neuroscience

authors： Bagley EE,Hacker J,Chefer VI,Mallet C,McNally GP,Chieng BC,Perroud J,Shippenberg TS,Christie MJ

更新日期：2011-10-30 00:00:00

abstract：:Several ion channels are thought to be directly modulated by nitric oxide (NO), but the molecular basis of this regulation is unclear. Here we show that the NMDA receptor (NMDAR)-associated ion channel was modulated not only by exogenous NO but also by endogenous NO. Site-directed mutagenesis identified a critical cys...

journal_title：Nature neuroscience

authors： Choi YB,Tenneti L,Le DA,Ortiz J,Bai G,Chen HS,Lipton SA

更新日期：2000-01-01 00:00:00

abstract：:Neural-derived signals are crucial regulators of CNS vascularization. However, whether the vasculature responds to these signals by means of elongating and branching or in addition by building a feedback response to modulate neurodevelopmental processes remains unknown. In this study, we identified bidirectional cross...

journal_title：Nature neuroscience

authors： Paredes I,Vieira JR,Shah B,Ramunno CF,Dyckow J,Adler H,Richter M,Schermann G,Giannakouri E,Schirmer L,Augustin HG,Ruiz de Almodóvar C

更新日期：2021-01-28 00:00:00