Abstract：
:Sensorimotor integration is crucial to perception and motor control. How and where this process takes place in the brain is still largely unknown. Here we analyze the cerebellar contribution to sensorimotor integration in the whisker system of mice. We identify an area in the cerebellum where cortical sensory and motor inputs converge at the cellular level. Optogenetic stimulation of this area affects thalamic and motor cortex activity, alters parameters of ongoing movements and thereby modifies qualitatively and quantitatively touch events against surrounding objects. These results shed light on the cerebellum as an active component of sensorimotor circuits and show the importance of sensorimotor cortico-cerebellar loops in the fine control of voluntary movements.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Proville RD,Spolidoro M,Guyon N,Dugué GP,Selimi F,Isope P,Popa D,Léna Cdoi
10.1038/nn.3773subject
Has Abstractpub_date
2014-09-01 00:00:00pages
1233-9issue
9eissn
1097-6256issn
1546-1726pii
nn.3773journal_volume
17pub_type
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