Encoding a temporally structured stimulus with a temporally structured neural representation.

Abstract:

:Sensory neural systems use spatiotemporal coding mechanisms to represent stimuli. These time-varying response patterns sometimes outlast the stimulus. Can the temporal structure of a stimulus interfere with, or even disrupt, the spatiotemporal structure of the neural representation? We investigated this potential confound in the locust olfactory system. When odors were presented in trains of nearly overlapping pulses, responses of first-order interneurons (projection neurons) changed reliably, and often markedly, with pulse position as responses to one pulse interfered with subsequent responses. However, using the responses of an ensemble of projection neurons, we could accurately classify the odorants as well as characterize the temporal properties of the stimulus. Further, we found that second-order follower neurons showed firing patterns consistent with the information in the projection-neuron ensemble. Thus, ensemble-based spatiotemporal coding could disambiguate complex and potentially confounding temporally structured sensory stimuli and thereby provide an invariant response to a stimulus presented in various ways.

journal_name

Nat Neurosci

journal_title

Nature neuroscience

authors

Brown SL,Joseph J,Stopfer M

doi

10.1038/nn1559

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

1568-76

issue

11

eissn

1097-6256

issn

1546-1726

pii

nn1559

journal_volume

8

pub_type

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