Abstract:
:Sensory neural systems use spatiotemporal coding mechanisms to represent stimuli. These time-varying response patterns sometimes outlast the stimulus. Can the temporal structure of a stimulus interfere with, or even disrupt, the spatiotemporal structure of the neural representation? We investigated this potential confound in the locust olfactory system. When odors were presented in trains of nearly overlapping pulses, responses of first-order interneurons (projection neurons) changed reliably, and often markedly, with pulse position as responses to one pulse interfered with subsequent responses. However, using the responses of an ensemble of projection neurons, we could accurately classify the odorants as well as characterize the temporal properties of the stimulus. Further, we found that second-order follower neurons showed firing patterns consistent with the information in the projection-neuron ensemble. Thus, ensemble-based spatiotemporal coding could disambiguate complex and potentially confounding temporally structured sensory stimuli and thereby provide an invariant response to a stimulus presented in various ways.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Brown SL,Joseph J,Stopfer Mdoi
10.1038/nn1559subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1568-76issue
11eissn
1097-6256issn
1546-1726pii
nn1559journal_volume
8pub_type
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