Abstract：
:The orbitofrontal cortex plays a central role in good-based economic decisions. When subjects make choices, neurons in this region represent the identities and values of offered and chosen goods. Notably, choices in different behavioral contexts may involve a potentially infinite variety of goods. Thus a fundamental question concerns the stability versus flexibility of the decision circuit. Here we show in rhesus monkeys that neurons encoding the identity or the subjective value of particular goods in a given context 'remap' and become associated with different goods when the context changes. At the same time, the overall organization of the decision circuit and the function of individual cells remain stable across contexts. In particular, two neurons supporting the same decision in one context also support the same decision in different contexts. These results demonstrate how the same neural circuit can underlie economic decisions involving a large variety of goods.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Xie J,Padoa-Schioppa Cdoi
10.1038/nn.4300subject
Has Abstractpub_date
2016-06-01 00:00:00pages
855-61issue
6eissn
1097-6256issn
1546-1726pii
nn.4300journal_volume
19pub_type
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journal_title：Nature neuroscience
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更新日期：2015-06-01 00:00:00
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更新日期：2007-06-01 00:00:00
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更新日期：2013-08-01 00:00:00
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更新日期：2008-07-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2013-11-01 00:00:00
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更新日期：2009-07-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2009-04-01 00:00:00
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