Coffee consumption and risk of stroke in women.

abstract：BACKGROUND AND PURPOSE:Cerebral white matter hyperintensities (WMHs) are believed to be the consequence of small vessel disease, and it is uncertain whether their extent predicts the risk of dementia in patients with vascular disease history. Method- Brain MRI was performed in 226 participants of the PROGRESS study. WM...

journal_title：Stroke

authors： Dufouil C,Godin O,Chalmers J,Coskun O,MacMahon S,Tzourio-Mazoyer N,Bousser MG,Anderson C,Mazoyer B,Tzourio C,PROGRESS MRI Substudy Investigators.

更新日期：2009-06-01 00:00:00

abstract：:Naloxone has been reported to have potential benefit in the treatment of stroke. We evaluated the effect of naloxone in a double-blind trial conducted with 15 stroke patients whose deficits ranged from 8 to 60 hours in duration. All but one patient sustained a cerebral infarction. Neurologic function was assessed befo...

journal_title：Stroke

authors： Fallis RJ,Fisher M,Lobo RA

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-intensity transient signals (HITS) detected by transcranial Doppler ultrasonography correspond to microemboli in intracranial arteries. The purpose of this study was to develop new diagnostic criteria for the differentiation of these microembolic signals from artifact, based on a high-resolu...

journal_title：Stroke

authors： Ries F,Tiemann K,Pohl C,Bauer C,Mundo M,Becher H

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler ultrasonography (TCD) is the standard technique for monitoring emboli in the cerebral circulation. Embolic signals have been detected with the use of this technique in most patients undergoing coronary artery bypass surgery. We previously reported that the majority of emboli ...

journal_title：Stroke

authors： Barbut D,Yao FS,Hager DN,Kavanaugh P,Trifiletti RR,Gold JP

更新日期：1996-01-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preischemic spontaneous locomotor activity was distinguished in this laboratory as a factor influencing outcome after 15 and 20 minutes of forebrain ischemia in gerbils. Histological investigations were carried out to analyze potential relations between postischemic survival and a reduction of ce...

journal_title：Stroke

authors： Stummer W,Weber K,Tranmer B,Baethmann A,Kempski O

更新日期：1994-09-01 00:00:00

abstract：:Background and Purpose- In this era of endovascular therapy (EVT) with early, complete recanalization and reperfusion, we have observed an even more rapid apparent diffusion coefficient (ADC) normalization within the acute ischemic lesion compared with the natural history or IV-tPA-treated patient. In this study, we a...

journal_title：Stroke

authors： Hsia AW,Luby M,Cullison K,Burton S,Armonda R,Liu AH,Leigh R,Nadareishvili Z,Benson RT,Lynch JK,Latour LL

更新日期：2019-08-01 00:00:00

abstract：:Non-invasive vascular testing has proven to be an effective means of identifying patients with significant extracranial carotid artery disease. Such tests can yield valuable physiologic data in patients with TIAs and can identify patients with soft signs who may have significant carotid artery disease and who may be c...

journal_title：Stroke

authors： Goran A,Moore G

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is no...

journal_title：Stroke

authors： Söderholm M,Zia E,Hedblad B,Engström G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An association between high lipoprotein(a) [Lp(a)] levels and positive Chlamydia pneumoniae IgG titers in coronary artery disease has been described. The possibility of predicting ischemic stroke by measurements of plasma Lp(a) and C pneumoniae antibodies was investigated. METHODS:This incident ...

journal_title：Stroke

authors： Glader CA,Stegmayr B,Boman J,Stenlund H,Weinehall L,Hallmans G,Dahlén GH

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Methods of performing and reporting randomized clinical trials (RCTs) are available, but weaknesses still occur. For observational studies, methodology is less well described, and weaknesses are even more likely. In recent guidelines for patients with subarachnoid hemorrhage (SAH), 25% of treatme...

journal_title：Stroke

authors： van der Schaaf IC,Ruigrok YM,Rinkel GJ,Algra A,van Gijn J

更新日期：2002-08-01 00:00:00

abstract：:We tested the hypothesis that hypertension is more common and cardiac embolism less common in patients with lacunar infarction than in patients with other types of cerebral infarction. We studied risk factor profiles in a series of 102 consecutive patients with a lacunar infarct and 202 consecutive patients with a car...

journal_title：Stroke

authors： Lodder J,Bamford JM,Sandercock PA,Jones LN,Warlow CP

更新日期：1990-03-01 00:00:00

abstract：:Background and Purpose- Prestroke dependence is an exclusion criterion in most trials of endovascular treatment (EVT) for acute ischemic stroke. Little is known about outcomes after EVT in these patients. We compared outcome and safety of EVT between prestroke-dependent and prestroke-independent patients. Methods- We ...

journal_title：Stroke

authors： Goldhoorn RB,Verhagen M,Dippel DWJ,van der Lugt A,Lingsma HF,Roos YBWEM,Majoie CBLM,Vos JA,Boiten J,van Zwam WH,van Oostenbrugge RJ,van den Wijngaard I,MR CLEAN Registry Investigators.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Cincinnati Prehospital Stroke Scale (CPSS) is recommended for emergency medical services use in identifying patients with stroke. Data evaluating its performance in the field are limited. We assessed the impact of training and use of the CPSS on the accuracy of paramedics' stroke patient iden...

journal_title：Stroke

authors： Frendl DM,Strauss DG,Underhill BK,Goldstein LB

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of the cerebroprotective effects of selective brain cooling have failed to show amelioration of ischemic injury in the cerebral cortex. This study was designed to test the hypothesis that mild-to-moderate selective brain cooling initiated after the onset of global brain ischemia in rats p...

journal_title：Stroke

authors： Kuluz JW,Gregory GA,Yu AC,Chang Y

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...

journal_title：Stroke

authors： Noor R,Wang CX,Shuaib A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Large pulse pressure associates with atherosclerosis, but it is unclear if it contributes to the development of atherosclerosis or if atherosclerosis leads to pulse pressure widening. We examined whether exposure to large pulse pressure in childhood predicts carotid artery intima-media thickness ...

journal_title：Stroke

authors： Raitakari OT,Juonala M,Taittonen L,Jula A,Laitinen T,Kähönen M,Viikari JS

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animal models of cerebral ischemia, matrix metalloproteinase (MMP) expression was significantly increased and related to blood-brain barrier disruption, edema formation, and hemorrhagic transformation (HT). MMP inhibitors reduce HT after embolic ischemia in tissue-type plasminogen activator-tr...

journal_title：Stroke

authors： Montaner J,Alvarez-Sabín J,Molina CA,Anglés A,Abilleira S,Arenillas J,Monasterio J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy of neuroprotective approaches in stroke may be influenced by existing comorbidities. Here, we compared the effects of normobaric hyperoxia (NBO) in normotensive versus hypertensive rats subjected to transient focal cerebral ischemia. METHODS:Male Sprague-Dawley and spontaneously hyp...

journal_title：Stroke

authors： Lan J,Esposito E,Ayata C,Singhal AB,Lo EH,Ji X

更新日期：2018-06-01 00:00:00

abstract：:To evaluate the role of platelet function in the pathogenesis of cerebral vasospasm, we compared sequential changes of platelet aggregability and beta-thromboglobulin and thromboxane B2 concentrations in blood samples from the internal jugular and peripheral vein of 13 patients with aneurysmal subarachnoid hemorrhage....

journal_title：Stroke

authors： Ohkuma H,Suzuki S,Kimura M,Sobata E

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...

journal_title：Stroke

authors： Mentias A,Heller E,Vaughan Sarrazin M

更新日期：2020-07-01 00:00:00

abstract：:Background and Purpose- Information on what effect disability before stroke can have on stroke outcome is lacking. We assessed prestroke disability in relation to poststroke hospital outcome. Methods- Analysis of prospectively collected data from the Sentinel Stroke National Audit Programme. A total of 1656 men (mean ...

journal_title：Stroke

authors： Han TS,Fry CH,Gulli G,Affley B,Robin J,Irvin-Sellers M,Fluck D,Kakar P,Sharma S,Sharma P

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Interhemispheric inhibition via the corpus callosum has been proposed as an exacerbating factor in outcome from stroke. METHODS:We measured infarct volume and behavioral outcome after middle cerebral artery occlusion in callosotomized rats and acallosal mice. RESULTS:Neither callosotomy in rats...

journal_title：Stroke

authors： Jin K,Xie L,Sun F,Mao X,Greenberg DA

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion-weighted MRI can demonstrate decreases of the apparent diffusion coefficient (ADC) of brain tissue water shortly after the onset of ischemia. To further elucidate underlying mechanisms, this study extended diffusion assessment to intracellular metabolites in rat brain in vivo before, du...

journal_title：Stroke

authors： Wick M,Nagatomo Y,Prielmeier F,Frahm J

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous thromboembolism and ischemic stroke are associated with unfavorable fibrin clot structure and function. We hypothesized that denser fibrin networks displaying impaired lysability characterize patients with cerebral venous sinus thrombosis (CVST). METHODS:We assessed plasma fibrin clot pro...

journal_title：Stroke

authors： Siudut J,Świat M,Undas A

更新日期：2015-09-01 00:00:00

abstract：:Endovascular acute ischemic stroke therapy is now proven by randomized controlled trials to produce large, clinically meaningful benefits. In response, stroke systems of care must change to increase timely and equitable access to this therapy. In this review, we provide a North American perspective on implications for...

journal_title：Stroke

authors： Smith EE,Schwamm LH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral infarction (DCI) is an important cause of poor outcome after subarachnoid hemorrhage. Cerebral perfusion is a predictor for DCI. Because acute hydrocephalus may impair cerebral perfusion, we evaluated the predictive value of the extent of acute hydrocephalus on the development of...

journal_title：Stroke

authors： Bakker AM,Dorhout Mees SM,Algra A,Rinkel GJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS:Adult male wild-type or PAR-1 knock...

journal_title：Stroke

authors： Wang J,Jin H,Hua Y,Keep RF,Xi G

更新日期：2012-09-01 00:00:00

abstract：:During perinatal asphyxia, cerebral blood flow is markedly reduced in the gray and white matter of the telencephalon. Since previous work has implicated prostaglandins in the control of blood flow, we tested the hypothesis that a thromboxane synthesis inhibitor would improve cerebral blood flow and blunt the metabolic...

journal_title：Stroke

authors： Ment LR,Stewart WB,Petroff OA,Duncan CC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the reproducibility, interobserver variability, and application to clinical studies of a new method for the quantitative assessment of carotid plaque echogenicity. METHODS:Carotid plaques were scanned with the use of ultrasound, and their images were stored in a computer. The...

journal_title：Stroke

authors： Sabetai MM,Tegos TJ,Nicolaides AN,Dhanjil S,Pare GJ,Stevens JM

更新日期：2000-09-01 00:00:00