Altered Fibrin Clot Properties in Patients With Cerebral Venous Sinus Thrombosis: Association With the Risk of Recurrence.

abstract：BACKGROUND AND PURPOSE:The combination of low-dose aspirin and dipyridamole is more effective than aspirin alone in reducing the risk of recurrent stroke and other major cardiovascular events in patients with a recent transient ischemic attack or minor stroke. It is unknown whether this also applies to patients with a ...

journal_title：Stroke

authors： Dippel DW,Maasland L,Halkes P,Kappelle LJ,Koudstaal PJ,Algra A,ESPRIT Study Group and the ESPS-2 Investigators.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined sex-specific relationships of smoking with risk of total stroke and stroke subtypes in Asian populations because of the limited data available. METHODS:A total of 19,782 men and 21,500 women aged 40 to 59 years who were free of prior diagnosis of stroke, coronary heart disease, or ca...

journal_title：Stroke

authors： Mannami T,Iso H,Baba S,Sasaki S,Okada K,Konishi M,Tsugane S,Japan Public Health Center-Based Prospective Study on Cancer and Cardiovascular Disease Group.

更新日期：2004-06-01 00:00:00

abstract：:Background and Purpose- Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral hemorrhage (ICH). In the current study, we investigated the therapeutic effect of retinoid X receptor agonist, bexarotene, i...

journal_title：Stroke

authors： Chang CF,Massey J,Osherov A,Angenendt da Costa LH,Sansing LH

更新日期：2020-02-01 00:00:00

abstract：:During perinatal asphyxia, cerebral blood flow is markedly reduced in the gray and white matter of the telencephalon. Since previous work has implicated prostaglandins in the control of blood flow, we tested the hypothesis that a thromboxane synthesis inhibitor would improve cerebral blood flow and blunt the metabolic...

journal_title：Stroke

authors： Ment LR,Stewart WB,Petroff OA,Duncan CC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the modified Rankin Scale (mRS) is the most commonly used primary end point in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the 7 Rankin levels by utilities ma...

journal_title：Stroke

authors： Chaisinanunkul N,Adeoye O,Lewis RJ,Grotta JC,Broderick J,Jovin TG,Nogueira RG,Elm JJ,Graves T,Berry S,Lees KR,Barreto AD,Saver JL,DAWN Trial and MOST Trial Steering Committees.,Additional contributors from DAWN Trial Steering

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

journal_title：Stroke

authors： Rothwell PM,Slattery J,Warlow CP

更新日期：1996-02-01 00:00:00

abstract：:Endothelium dysfunction may result from increased production of reactive oxygen species and decreased availability of nitric oxide. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (ie, statins) exert cholesterol-independent vasoprotective effects that are mediated, in part, through the inhibiti...

journal_title：Stroke

authors： Endres M,Laufs U

更新日期：2004-11-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) pandemic has broad implications on stroke patient triage. Emergency medical services providers have to ensure timely transfer of patients while minimizing the risk of infectious exposure for themselves, their co-workers, and other patients. This statement paper provides a concep...

journal_title：Stroke

authors： Goyal M,Ospel JM,Southerland AM,Wira C,Amin-Hanjani S,Fraser JF,Panagos P,AHA\/ASA Stroke Council Science Subcommittees: Emergency Neurovascular Care (ENCC), the Telestroke and the Neurovascular Intervention Committees.

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, as measured by common carotid intima-media thickness and carotid pla...

journal_title：Stroke

authors： Bots ML,Ford I,Lloyd SM,Laurent S,Touboul PJ,Hennerici MG,Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin With Terutroban in Patients With a History of Ischemic Stroke or Transient Ischemic Attack Vascular Ultrasou

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Close relations between leukoaraiosis detected by computed tomography or magnetic resonance imaging and stroke, particularly lacunar infarction, have been reported. We studied whether leukoaraiosis is related to long-term prognosis for patients with lacunar infarction. METHODS:We examined monthl...

journal_title：Stroke

authors： Miyao S,Takano A,Teramoto J,Takahashi A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction. METHODS:We conducted a randomized, multicenter, blinded pi...

journal_title：Stroke

authors： Bruno A,Kent TA,Coull BM,Shankar RR,Saha C,Becker KJ,Kissela BM,Williams LS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral blood flow is coupled to brain metabolism by means of active modulation of cerebrovascular resistance. This homeostatic vasogenic activity is reflected in slow waves of cerebral blood flow velocities (FV) which can also be detected in intracranial pressure (ICP). However, effects of incr...

journal_title：Stroke

authors： Haubrich C,Czosnyka Z,Lavinio A,Smielewski P,Diehl RR,Pickard JD,Czosnyka M

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcatheter closure of patent foramen ovale (PFO) has been reported to improve migraine in patients with cerebrovascular disorders in noncontrolled studies. The aim of the study was to compare the course of migraine assessed prospectively over a 12-month period in symptomatic (for cerebrovascul...

journal_title：Stroke

authors： Anzola GP,Frisoni GB,Morandi E,Casilli F,Onorato E

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Research on the relationship between caffeine-containing medicines (CCMs) and the risk of hemorrhagic stroke (HS) is sparse. The aim of this study is to evaluate the association between CCMs and the risk of HS. METHODS:We performed a multicenter case-control study in South Korea, from 2002 to 20...

journal_title：Stroke

authors： Lee SM,Choi NK,Lee BC,Cho KH,Yoon BW,Park BJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

journal_title：Stroke

authors： McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

更新日期：2020-08-01 00:00:00

abstract：:The value of the concomittant use of a real time frequency analyzer along with a continuous wave carotid Doppler scanner is demonstrated in this study of 118 cases. With a colour-coded Doppler scanner alone, internal carotid stenoses greater than 35% were diagnosed with a sensitivity of 95% and a specificity of 82%. W...

journal_title：Stroke

authors： Johnston KW,Brown PM,Kassam M

更新日期：1982-09-01 00:00:00

abstract：:The gerbil model was used to assess the therapeutic effects of the calcium antagonist nimodipine on cerebral ischemia. Transient cerebral ischemia was produced in each gerbil by bilateral common carotid occlusion of 10-, 15- or 20-min duration. Nimodipine (0.01 or 0.1 mg/kg) was administered intraperitoneally just bef...

journal_title：Stroke

authors： Fujisawa A,Matsumoto M,Matsuyama T,Ueda H,Wanaka A,Yoneda S,Kimura K,Kamada T

更新日期：1986-07-01 00:00:00

abstract：:Naloxone has been reported to have potential benefit in the treatment of stroke. We evaluated the effect of naloxone in a double-blind trial conducted with 15 stroke patients whose deficits ranged from 8 to 60 hours in duration. All but one patient sustained a cerebral infarction. Neurologic function was assessed befo...

journal_title：Stroke

authors： Fallis RJ,Fisher M,Lobo RA

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microembolic signals (MESs) are detectable within the transcranial Doppler frequency spectrum downstream from vascular atherothrombotic or cardiothrombotic lesions. A frequent occurrence of MESs has also been shown during bypass surgery or after mechanical valve implantation. We sought to compile...

journal_title：Stroke

authors： Dittrich R,Ringelstein EB

更新日期：2008-02-01 00:00:00

abstract：:Contrast-enhanced computed tomography of the neck permits low-risk evaluation of morphologic complications of carotid plaque, including (and foremost) calcification. To investigate the patterns and clinical significance of calcified deposits in the cervical carotid arteries using computed tomography we studied 40 pati...

journal_title：Stroke

authors： Culebras A,Otero C,Toledo JR,Rubin BS

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke patients without evidence of arterial occlusion may not be suitable candidates for thrombolytic therapy. In our study, we investigated the outcomes of patients with negative CT angiography results for arterial occlusion. METHODS:The study included patients treated within 3 hours after sym...

journal_title：Stroke

authors： Mikulik R,Goldemund D,Reif M,Aulicky P,Krupa P

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain injury caused by stroke is a frequent cause of perinatal morbidity and mortality with limited therapeutic options. Mesenchymal stem cells (MSC) have been shown to improve outcome after neonatal hypoxic-ischemic brain injury mainly by secretion of growth factors stimulating repair processes....

journal_title：Stroke

authors： van Velthoven CT,Sheldon RA,Kavelaars A,Derugin N,Vexler ZS,Willemen HL,Maas M,Heijnen CJ,Ferriero DM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Copeptin has been associated with recurrent cerebrovascular events after transient ischemic attack (TIA). In an independent cohort, we evaluated copeptin for the prediction of recurrent cerebrovascular events within 3 months after TIA and assessed the incremental value of copeptin compared with t...

journal_title：Stroke

authors： De Marchis GM,Weck A,Audebert H,Benik S,Foerch C,Buhl D,Schuetz P,Jung S,Seiler M,Morgenthaler NG,Mattle HP,Mueller B,Christ-Crain M,Arnold M,Katan M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We used a rat model of reversible spinal ischemia to assess the effect of spinal cord temperature on the development of neurological and histopathologic changes after 20 minutes of reversible aortic occlusion. Spinal cord blood flow and CO2 reactivity was tested by using laser Doppler before and ...

journal_title：Stroke

authors： Marsala M,Vanicky I,Yaksh TL

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Silent cerebrovascular disease (CVD) has been proposed as a predisposing condition for clinically overt stroke and vascular dementia. Recently, we found increased thrombin generation in silent CVD patients. Here, we report the effect of thrombin inhibition using a potent selective thrombin inhibi...

journal_title：Stroke

authors： Kario K,Matsuo T,Hoshide S,Umeda Y,Shimada K

更新日期：1999-05-01 00:00:00

abstract：:The literature on carotid surgery for lesions appropriate to prior episodes of ischemia has been reviewed. Only one randomized study and six non-controlled reports give useful data (this despite more than thirty years of surgical activity in this field). When analyzed by the IMPS (intact months of patient survival) cr...

journal_title：Stroke

authors： Jonas S

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Telestroke has been effective in the management of acute ischemic stroke. This study characterizes and compares stroke specialist (SS) and emergency physician (EP) perceptions of telestroke and identifies barriers preventing increased implementation. METHODS:A survey was developed and distribute...

journal_title：Stroke

authors： Moskowitz A,Chan YF,Bruns J,Levine SR

更新日期：2010-04-01 00:00:00

abstract：:U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion of alpha-tocopherol with the amine of the previously described 21-aminosteroids (e.g., U74006F). U78517F inhibited 200 microM FeCl2-initiated lipid peroxidation in rat brain homogenates by 50...

journal_title：Stroke

authors： Hall ED,Pazara KE,Braughler JM,Linseman KL,Jacobsen EJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Physical and psychological characteristics in adolescence are associated with subsequent stroke risk. Our aim is to investigate their relevance to length of hospital stay and risk of second stroke. METHODS:Swedish men born between 1952 and 1956 (n=237 879) were followed from 1987 to 2010 using i...

journal_title：Stroke

authors： Bergh C,Udumyan R,Appelros P,Fall K,Montgomery S

更新日期：2016-09-01 00:00:00