Abstract:
BACKGROUND AND PURPOSE:Transcatheter closure of patent foramen ovale (PFO) has been reported to improve migraine in patients with cerebrovascular disorders in noncontrolled studies. The aim of the study was to compare the course of migraine assessed prospectively over a 12-month period in symptomatic (for cerebrovascular disease) and asymptomatic patients undergoing PFO closure and in patients with PFO treated medically. METHODS:Twenty-three stroke symptomatic (SS; 39+/-10 years of age; males/females [M/F] 5/18) and 27 stroke asymptomatic (SA; 40+/-12 years of age; M/F 5/22) patients with migraine underwent PFO closure. Twenty-seven patients with migraine and PFO (controls [CTRLS]; 36+/-11 years of age; M/F 4/23) were followed up medically. Migraine severity was assessed at baseline with a scale that takes into account the frequency, duration, and intensity of the attacks and the occurrence of aura (score range 0 to 10). Six months later, the patients were given a structured diary to annotate monthly with the same scale the characteristics of the attacks for the next 6 months. By the end of 1 year, the migraine score was averaged for the last 6 months. RESULTS:Baseline severity of migraine did not differ between groups (6.3 to 6.1 and 6.7 in SS, SA, and CTRLS groups, respectively). At the 1-year assessment, the overall migraine score had significantly improved by 3.7 and 2.8 points in SS and SA, respectively (P<0.001 on repeated-measure ANOVA), whereas it had nonsignificantly worsened by 0.1 points in CTRLS. Multiple linear regression analysis showed that the improvement in SS and SA was independent of migraine type, age, and cerebrovascular risk factors. Twenty-one of 21 patients with migraine with aura in the CTRLS group still had aura at the end of follow-up, whereas only 3 of 14 among SA and 4 of 19 among SS continued to have migraine preceded by aura (P<0.0001 on Fisher exact test). CONCLUSIONS:Compared with medical treatment, closure of PFO brings about a significant overall improvement in migraine. This seems to occur irrespective of migraine type and of previous cerebrovascular disease. In addition to the overall improvement, in migraine with aura, the occurrence of aura is dramatically reduced.
journal_name
Strokejournal_title
Strokeauthors
Anzola GP,Frisoni GB,Morandi E,Casilli F,Onorato Edoi
10.1161/01.STR.0000199082.07317.43subject
Has Abstractpub_date
2006-02-01 00:00:00pages
430-4issue
2eissn
0039-2499issn
1524-4628pii
01.STR.0000199082.07317.43journal_volume
37pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Wall shear stress (WSS) is one of the main pathogenic factors in the development of saccular cerebral aneurysms. The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD). METHODS:Twenty ma...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000144648.89172.0f
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The most powerful predictors of functional recovery and eventual home discharge among stroke survivors are the initial severity of the stroke and the patient's age. We analyzed a large population of stroke rehabilitation admissions by stratifying subgroups with coherent outcomes in an attempt to ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.1.128
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We investigated changes in locomotor activity, passive avoidance task performance, and hippocampal CA1 neurons induced by cerebral ischemia in Mongolian gerbils to examine the relation between these behavioral changes and CA1 neuronal damage. METHODS:Spontaneous locomotor activity was measured u...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.3.645
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke. METHODS:Using dietary information collected in 1984 from 71,768 women aged 38 to 63 years without a history of cardiova...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000135762.89154.92
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A high incidence of arteriovenous malformations (AVMs) is associated with hereditary hemorrhagic telangiectasia type 1. Endoglin, the gene mutated in this disorder, is expressed at reduced levels on blood vessels of these patients. Since endoglin is a component of the transforming growth factor-b...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.11.2653
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The remaining limitations of ultrasonographic imaging in accurately quantifying internal carotid stenosis or diagnosing internal carotid occlusion may be overcome by enhancing the echogenicity of flowing arterial blood with contrast agents. This study assessed the usefulness of the intravenous (t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.2.385
更新日期:1994-02-01 00:00:00
abstract::This study, in biologically bred hyperglycemic diabetic rats, examined the effect of a intravenous insulin infusion (1.5 units.hr-1) on blood, plasma, and brain glucose concentrations to determine their relationship during decreasing blood and plasma glucose levels. The data were compared to saline-treated diabetic ra...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.4.505
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A potential way to improve prehospital stroke care and patient handoff is hospital-directed feedback for emergency medical service (EMS) providers. We evaluated whether a hospital-directed EMS stroke follow-up tool improved documentation of adherence to the Rhode Island state prehospital stroke p...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.005679
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Waist circumference has been shown to be a better predictor of cardiovascular risk than body mass index (BMI). Our case-control study aimed to evaluate the contribution of obesity and abdominal fat mass to the risk of stroke and transient ischemic attacks (TIA). METHODS:We recruited 1137 partici...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.523001
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The genetic basis of white matter hyperintensities (WMH) is still unknown. This study examines the heritability of WMH in both sexes and in different brain regions, and the influence of age. METHODS:Participants from the Older Australian Twins Study were recruited (n=320; 92 monozygotic and 68 d...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.012532
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We tested the hypothesis that sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, promotes functional recovery and neurogenesis after stroke. METHODS:Male Wistar rats were subjected to embolic middle cerebral artery occlusion. Sildenafil (Viagra) was administered orally for 7 consecutive da...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000034399.95249.59
更新日期:2002-11-01 00:00:00
abstract::We reviewed demographic data on patients having 2,256 carotid endarterectomies in eight large hospitals in North Carolina to determine the frequency of blacks among these patients. Blacks comprised only 4.6% of the patients having carotid endarterectomy even though they comprised 26% of all patients discharged and 22%...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.1.22
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Postischemic cerebral inflammation may contribute to ischemic cell damage. Intercellular adhesion molecule-1 (ICAM-1) is a glycoprotein expressed on endothelial cells that facilitates leukocyte adhesion. We investigated the effect of administration of an anti-ICAM-1 antibody (1A29) on ischemic ce...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.8.1438
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:High-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) are hypothesized to be biomarkers of systemic inflammation and risk of myocardial infarction (MI) and stroke. Little is known, however, about the stability of these markers over time, and in particul...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.552802
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral h...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.008121
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Thick cisternal clot on CT is a well-recognized risk factor for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). Whether intraventricular hemorrhage (IVH) or intracerebral hemorrhage (ICH) predisposes to DCI is unclear. The Fisher CT grading scale identifies thick SAH but does...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/hs0901.095677
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Guidelines advocate screening all acute stroke patients for dysphagia. However, limited data are available regarding how many and which patients are screened and how failing a swallowing screen affects patient outcomes. We sought to evaluate predictors of receiving dysphagia screening after acute...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.015332
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.030256
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The objective of this study was to determine the prevalence of intracranial plaques and stenoses and their causal role in patients with fatal stroke. Intracranial atherosclerosis is considered to be a rare condition with a severe prognosis. However, disease prevalence may be underestimated due to...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.496513
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/hs1001.097099
更新日期:2001-10-01 00:00:00
abstract::Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022606
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Deteriorating glucose tolerance is associated with an increased cardiovascular disease (CVD) risk. The underlying mechanisms remain unclear. Arterial remodeling is the change in structural properties through time in response to atherogenic and/or hemodynamic alterations and aims to maintain circu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000115752.58601.0B
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The EuroQol and Medical Outcome Survey 36-item short-form health survey (SF-36) questionnaires have both been validated for the assessment of health-related quality of life after stroke. However, the relationship between these instruments has not been studied after stroke. We therefore sought to ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.30.10.2146
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intravenous tissue plasminogen activator (tPA) is an economically worthwhile but underused treatment option for acute ischemic stroke. We sought to identify the extent of tPA use in Canadian medical centers and the potential savings associated with increased use nationally and by province. METHO...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.106.479477
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The objectives of the present study were to: (1) noninvasively identify white matter reorganization and monitor its progress within 6 weeks after the onset of stroke; and (2) quantitatively investigate the effect of recombinant human erythropoietin treatment on this structural change using in viv...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.527713
更新日期:2009-03-01 00:00:00
abstract::As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.700
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Short-term elevations in fine particulate matter air pollution (PM2.5) are associated with increased risk of acute cerebrovascular events. Evidence from the peripheral circulation suggests that vascular dysfunction may be a central mechanism. However, the effects of PM2.5 on cerebrovascular funct...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000395
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. METHODS:We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (<48 hours from onset for acute stroke or >6 months after stroke for chronic s...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.570374
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.595322
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Physiologically, it appears plausible for physical activity to decrease stroke risk; however, epidemiological studies have produced mixed findings. Furthermore, few studies have examined specific kinds and intensities of activities. The purpose of this study was to examine the association between...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.10.2049
更新日期:1998-10-01 00:00:00