Abstract:
BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using an epidemiologically derived sample of first-time stroke survivors from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) study. METHODS:Participants of REGARDS who reported a first-time stroke event during regular surveillance calls were interviewed by telephone and then completed an in-home evaluation approximately 1 year after the verified first-time stroke event (N=112). A primary family caregiver was also enrolled and interviewed for each stroke survivor. Measures from the in-home evaluation included previously validated stroke outcomes assessments of neurological deficits, functional impairments, and patient-reported effects of stroke in multiple domains. Results- African American stroke survivors were less likely to be living with their primary family caregivers than white participants. Analyses that controlled for age, education, and whether the stroke survivors lived with their primary family caregivers indicated that African Americans and women showed significantly greater deficits on multiple 1-year outcome measures compared to whites and men, respectively. CONCLUSIONS:Among community-dwelling stroke survivors with family caregivers, women and African Americans are at heightened risk for poor long-term outcomes 1 year after first-time stroke events. Rehabilitation services and public health policies aimed at enhancing stroke recovery rates should address these disparities in poststroke outcomes.
journal_name
Strokejournal_title
Strokeauthors
Roth DL,Haley WE,Clay OJ,Perkins M,Grant JS,Rhodes JD,Wadley VG,Kissela B,Howard Gdoi
10.1161/STROKEAHA.110.595322subject
Has Abstractpub_date
2011-03-01 00:00:00pages
626-31issue
3eissn
0039-2499issn
1524-4628pii
STROKEAHA.110.595322journal_volume
42pub_type
杂志文章相关文献
STROKE文献大全abstract::Background and Purpose- We sought to explore the effect of genetic imbalance on functional outcome after ischemic stroke (IS). Methods- Copy number variation was identified in high-density single-nucleotide polymorphism microarray data of IS patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Pati...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.021856
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.031929
更新日期:2021-01-01 00:00:00
abstract::To elucidate the role of the internal elastic lamina in the development of cerebral aneurysm, the bifurcation of the anterior cerebral artery and olfactory artery was histologically studied in control and experimental rats treated with unilateral carotid ligation and renal hypertension. Various stages of aneurysm form...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.4.507
更新日期:1988-04-01 00:00:00
abstract::We studied ultrastructurally cerebral perforating arteries in 60 stroke-prone spontaneously hypertensive rats (SHRSP), which were sequentially killed at 4-52 weeks of age before showing symptoms of stroke. Another 24 SHRSP were killed soon after they showed symptoms of cerebral infarction. The initial vascular lesions...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.733
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A close correlation between B-mode sonography and the histopathology and surface structure of plaque is rarely seen in vivo with high-grade stenoses of the extracranial carotid artery. The goal of this study was to determine whether normalized gray scale analysis and surface analysis of the plaqu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000081982.85010.A8
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Thrombus within the carotid artery usually occurs in vessels with severe atherosclerotic disease and may embolize to cause transient ischemic attacks and cerebral infarctions. The risk factors for carotid artery thrombus formation in the absence of atherosclerosis are not well characterized. A case series is...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.5.1002
更新日期:1996-05-01 00:00:00
abstract::Spontaneous dissections of the extracranial internal carotid artery are diagnosed more frequently as their clinical and angiographic features are more widely recognized. Familial occurrence of spontaneous dissection of the internal carotid artery has not been previously reported. We describe the occurrence of this ent...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.246
更新日期:1987-01-01 00:00:00
abstract::Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of strept...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.6.1148
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.013982
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS:We retrospectively analyzed...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017420
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Embolization with coils is increasingly used for the treatment of intracranial aneurysms. To assess the percentage of complications, the percentage of aneurysm occlusion, and the short-term outcome, we performed a systematic review of studies on embolization with controlled detachable or pushable coils. SUM...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.30.2.470
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Improved methods of identifying patients at high risk of thromboembolism would allow improved targeting of therapy. One such situation is carotid artery stenosis. This is associated with an increased risk of stroke, which can be reduced by carotid endarterectomy. However, the risk-benefit ratio i...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.7.1440
更新日期:1999-07-01 00:00:00
abstract::An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.6.874
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Acute ischemic stroke in humans is associated with profound alterations in the immune system. Hallmarks of this stroke-induced immunodepression syndrome are: lymphocytopenia, impairment of T helper cell and monocyte function. We studied which stroke-specific factors predict these immunologic alte...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.557967
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The management of carotid atherosclerosis is well-established for symptomatic stenosis above 69%, but the optimal approach for managing lower degrees of narrowing remains uncertain. Because the risk of stroke increases with higher grades of stenosis, we are inclined to consider low-grade disease ...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.STR.0000185726.83152.00
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Findings on transesophageal echocardiography (TEE) after ischemic stroke predict recurrent embolic events and prompt therapy; however, the additive predictive power of TEE findings on long-term mortality is unknown. Our goal was to study the impact of TEE findings on all cause mortality in ischem...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000196939.12313.16
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Rates of development of de novo intracranial aneurysms and of growth of untreated additional aneurysms are largely unknown. We performed MRA in a large patient cohort with coiled aneurysms at 5-year follow-up. METHODS:In 276 patients with coiled intracranial aneurysms and 5±0.5 years of follow-u...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,评审
doi:10.1161/STROKEAHA.110.591594
更新日期:2011-02-01 00:00:00
abstract::Recent data strongly suggest that repetitive ischemic episodes have an adverse cumulative effect on development of edema and tissue damage. We wanted to assess further whether special risks such as exacerbation of extracellular acidification reflecting progressive exhaustion of the capacity to buffer H+ in the extrace...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.8.1192
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Recent studies have shown the antiapoptotic neuroprotective effects of lecithinized superoxide dismutase (PC-SOD) in different forms of brain injury. We tested the effects of PC-SOD in focal cerebral ischemia in the rat middle cerebral artery occlusion model (MCAO). METHODS:Adult male Sprague-Da...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000257978.70312.1d
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. METHODS:This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 20...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.111.643130
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of this work was to investigate how stroke rehabilitation professionals understand the concept of motivation and the ways that they use this concept in their clinical practice. METHODS:This qualitative study used semistructured, in-depth interviews with the professionals working in t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/hs0202.102367
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is a major healthcare problem in both the United States (US) and the United Kingdom (UK). Little comparative data are available concerning how generalist physicians in the two countries approach the management of patients at high risk of stroke. METHODS:Contemporaneous surveys of random s...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.4.746
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The diagnosis and quantification of microangiopathy in dementia is difficult. The assessment of small-vessel disease requires expensive and sophisticated nuclear medicine techniques. This study was performed to identify microangiopathy related to the integrity of cerebral microcirculation by sono...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.11.2291
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Accumulation of iron after intracerebral hemorrhage causes free radical formation and oxidative damage resulting in liquefaction. The aim of this study was the investigation of molecular mechanisms underlying estrogen-mediated neuroprotective effect against iron-induced brain injury in vivo. MET...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.562850
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.113.001690
更新日期:2013-10-01 00:00:00
abstract::We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the fluorescein derivative rose bengal and focal illumination of the intact skull surface. Infarcted rats showed specific, long-lasting deficits in tactile and proprioceptive placing reactions o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.10.1383
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship between cerebral autoregulation and angiographic vasospasm (aVSP) and radiographic delayed cerebral ischemia (DCI) in patients with SAH. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.002630
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In prehension tasks with objects placed within arm's reach, patients with hemiparesis caused by stroke use excessive trunk movement to compensate for arm motor impairments. Compensatory trunk movements may improve motor function in the short term but may limit arm recovery in the long term. Previ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.STR.0000132569.33572.75
更新日期:2004-08-01 00:00:00
abstract::Occlusion of the anterior cerebral artery is a rare condition. A review of CT scans from 413 patients with ischemic infarction confirmed this low relative incidence: only 3% of CT scans evidencing infarction involved the territory of the anterior cerebral artery. Four major mechanisms of anterior cerebral artery occlu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.14.6.952
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The etiology of stroke in the young is different from that in older patients and remains unknown in almost one third of the cases. To gain further insight into both pathogenic and etiologic determinants, we prospectively studied a large number of consecutive young adults with focal cerebral ische...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.3.362
更新日期:1993-03-01 00:00:00