White Matter Hyperintensities Are Under Strong Genetic Influence.

abstract：BACKGROUND AND PURPOSE:To define desirable target low-density lipoprotein (LDL) cholesterol levels for the prevention of stroke recurrence, a post hoc analysis was performed in the J-STARS study (Japan Statin Treatment Against Recurrent Stroke). METHODS:Subjects (n=1578) were divided into groups based on mean value of...

journal_title：Stroke

authors： Hosomi N,Kitagawa K,Nagai Y,Nakagawa Y,Aoki S,Nezu T,Kagimura T,Maruyama H,Origasa H,Minematsu K,Uchiyama S,Matsumoto M,J-STARS Collaborators.

更新日期：2018-04-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to conduct a meta-analysis of CVOTs (cardiovascular outcome trials) to evaluate the effect of glucagon-like peptide-1 receptor agonists therapy in reducing the risk of stroke in patients with type 2 diabetes mellitus. Methods- PubMed and other electronic sources we...

journal_title：Stroke

authors： Bellastella G,Maiorino MI,Longo M,Scappaticcio L,Chiodini P,Esposito K,Giugliano D

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent studies have shown the antiapoptotic neuroprotective effects of lecithinized superoxide dismutase (PC-SOD) in different forms of brain injury. We tested the effects of PC-SOD in focal cerebral ischemia in the rat middle cerebral artery occlusion model (MCAO). METHODS:Adult male Sprague-Da...

journal_title：Stroke

authors： Tsubokawa T,Jadhav V,Solaroglu I,Shiokawa Y,Konishi Y,Zhang JH

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The consequences of stroke are a major health concern. This study was conducted to compare the health-related quality of life among long-term survivors of stroke with that of the general population. METHODS:Our data are taken from a population-based case-control study of all 6-year survivors of ...

journal_title：Stroke

authors： Hackett ML,Duncan JR,Anderson CS,Broad JB,Bonita R

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Shoulder pain is a common complication after stroke that can impede participation in rehabilitation and has been associated with poorer outcomes. Evidence-based treatments for hemiplegic shoulder pain are limited. Suprascapular nerve block (SSNB) is a safe and effective treatment of shoulder pain...

journal_title：Stroke

authors： Adey-Wakeling Z,Crotty M,Shanahan EM

更新日期：2013-11-01 00:00:00

abstract：:Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experienc...

journal_title：Stroke

authors： Yenari MA,Hemmen TM

更新日期：2010-10-01 00:00:00

abstract：:The effect of cigarette smoking on extracranial carotid atherosclerosis was studies by obtaining cigarette smoking histories and information on other potential risk factors from consecutive patients undergoing carotid arteriography. At least on extracranial carotid artery was visualized in 752 patients in whom the ext...

journal_title：Stroke

authors： Whisnant JP,Homer D,Ingall TJ,Baker HL Jr,O'Fallon WM,Wievers DO

更新日期：1990-05-01 00:00:00

abstract：:A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...

journal_title：Stroke

authors： Hawkins R,Hass WK,Ransohoff J

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the present study is to determine the effect of mild hypothermia on the synthesis of ubiquitin, an important protein for maintenance of cell viability, in the hippocampal neurons following transient cerebral ischemia. METHODS:Transient ischemia was induced by occluding both common...

journal_title：Stroke

authors： Yamashita K,Eguchi Y,Kajiwara K,Ito H

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, as measured by common carotid intima-media thickness and carotid pla...

journal_title：Stroke

authors： Bots ML,Ford I,Lloyd SM,Laurent S,Touboul PJ,Hennerici MG,Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin With Terutroban in Patients With a History of Ischemic Stroke or Transient Ischemic Attack Vascular Ultrasou

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is expanding literature to show that certain patients admitted during the weekend have worse outcomes than similar patients admitted during the week. Although many clinicians have hypothesized the presence of this "weekend effect" with patients with intracerebral hemorrhage, there is a pauc...

journal_title：Stroke

authors： Crowley RW,Yeoh HK,Stukenborg GJ,Medel R,Kassell NF,Dumont AS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The outcomes of carotid endarterectomy (CEA) are, in addition to patient baseline characteristics, highly dependent on the safety of the surgical procedure. During the successive stages of the operation, transcranial Doppler (TCD) monitoring of the middle cerebral artery (MCA) was used to assess ...

journal_title：Stroke

authors： Ackerstaff RG,Moons KG,van de Vlasakker CJ,Moll FL,Vermeulen FE,Algra A,Spencer MP

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rarity of intracranial vascular malformations (IVMs) and the infrequency of their outcomes make large, prolonged cohort studies the best means to evaluate their frequency and prognosis. METHODS:The Scottish Intracranial Vascular Malformation Study (SIVMS) is a prototype prospective, populati...

journal_title：Stroke

authors： Al-Shahi R,Bhattacharya JJ,Currie DG,Papanastassiou V,Ritchie V,Roberts RC,Sellar RJ,Warlow CP,Scottish Intracranial Vascular Malformation Study Collaborators.

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The management of carotid atherosclerosis is well-established for symptomatic stenosis above 69%, but the optimal approach for managing lower degrees of narrowing remains uncertain. Because the risk of stroke increases with higher grades of stenosis, we are inclined to consider low-grade disease ...

journal_title：Stroke

authors： Wasserman BA,Wityk RJ,Trout HH 3rd,Virmani R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral infarction (DCI) is an important cause of poor outcome after subarachnoid hemorrhage. Cerebral perfusion is a predictor for DCI. Because acute hydrocephalus may impair cerebral perfusion, we evaluated the predictive value of the extent of acute hydrocephalus on the development of...

journal_title：Stroke

authors： Bakker AM,Dorhout Mees SM,Algra A,Rinkel GJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that cerebral microembolism detected with transcranial Doppler sonography distal to internal carotid artery stenosis occurs more frequently in recently symptomatic compared with asymptomatic patients. It has remained unclear whether cerebral microembolism also indicates a ...

journal_title：Stroke

authors： Siebler M,Nachtmann A,Sitzer M,Rose G,Kleinschmidt A,Rademacher J,Steinmetz H

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) is associated with higher risk of periprocedural stroke and death when compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small, and ...

journal_title：Stroke

authors： Boulanger M,Camelière L,Felgueiras R,Berger L,Rerkasem K,Rothwell PM,Touzé E

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic ocular ischemia is a rare form of ischemia of the eye in patients with carotid artery occlusion (CAO). The early and often asymptomatic stage of chronic ocular ischemia is referred to as venous stasis retinopathy (VSR). The aim of this study was to gain insight into the prevalence, cause,...

journal_title：Stroke

authors： Klijn CJ,Kappelle LJ,van Schooneveld MJ,Hoppenreijs VP,Algra A,Tulleken CA,van Gijn J

更新日期：2002-03-01 00:00:00

abstract：:Background and Purpose- Stroke is the most frequent severe clinical event in patients with Fabry disease. We aimed to evaluate the cerebral magnetic resonance imaging findings of patients with Fabry disease and assess their association with future stroke risk after enzyme replacement therapy (ERT) induction. Methods- ...

journal_title：Stroke

authors： Yagita Y,Sakai N,Miwa K,Ohara N,Tanaka M,Sakaguchi M,Kitagawa K,Mochizuki H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To compare the utility of contrast-enhanced MR Angiography (CE-MRA) with digital subtraction angiography (DSA) after endovascular treatment of intracranial aneurysms with Guglielmi detachable coils. METHODS:From April 1999 to August 2002, 106 patients with 107 aneurysms treated by endovascular c...

journal_title：Stroke

authors： Gauvrit JY,Leclerc X,Caron S,Taschner CA,Lejeune JP,Pruvo JP

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...

journal_title：Stroke

authors： Noor R,Wang CX,Shuaib A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The most powerful predictors of functional recovery and eventual home discharge among stroke survivors are the initial severity of the stroke and the patient's age. We analyzed a large population of stroke rehabilitation admissions by stratifying subgroups with coherent outcomes in an attempt to ...

journal_title：Stroke

authors： Alexander MP

更新日期：1994-01-01 00:00:00

abstract：:In patients with subarachnoid hemorrhage, particularly hemorrhage due to aneurysmal rupture, there was a positive significant relation between angiographic vessel constriction and vessel pathology (angiopathy). Furthermore, there was a positive relationship between post-hemorrhage survival time and the severity of ang...

journal_title：Stroke

authors： Smith RR,Clower BR,Peeler DF Jr,Yoshioka J

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to clarify the association of chronic kidney disease (CKD) with carotid atherosclerosis and the impact of CKD on carotid atherosclerosis according to blood pressure categories in an urban general population. METHODS:We studied 3466 Japanese individuals (35-93 years old) in the Suita Stu...

journal_title：Stroke

authors： Ohara T,Kokubo Y,Toyoda K,Watanabe M,Koga M,Nakamura S,Nagatsuka K,Minematsu K,Nakagawa M,Miyamoto Y

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Deep intracerebral hemorrhage (ICH) and lacunar infarcts are the result of small vessel disease, whereas nonlacunar infarcts are often caused by large artery atherosclerosis or cardiac embolism. We hypothesized that patients with deep ICH and lacunar infarcts have similar retinal microvascular si...

journal_title：Stroke

authors： Baker ML,Hand PJ,Liew G,Wong TY,Rochtchina E,Mitchell P,Lindley RI,Hankey GJ,Wang JJ,Multi-Centre Retinal Stroke Study Group.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The mechanisms of immune reaction involved in the pathogenesis and clinical course of acute vascular incidents are still not completely understood. The aim of this study was to examine the presence of immune complexes (IC) in the acute stroke setting and the first month thereafter and to characte...

journal_title：Stroke

authors： Tarnacka B,Gromadzka G,Członkowska A

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is usually based on clinical assessment, blood test results, and CT findings. Intravenous thrombolysis of stroke mimics may occur but has not been studied in detail. METHODS:We determined frequency, clinical characteristics, and outcome of mimic...

journal_title：Stroke

authors： Winkler DT,Fluri F,Fuhr P,Wetzel SG,Lyrer PA,Ruegg S,Engelter ST

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of moyamoya disease (MMD) remains obscure. This study was undertaken to identify specific proteins associated with the pathogenesis of MMD. METHODS:We studied cerebrospinal fluid (CSF) from 20 patients with angiographically confirmed MMD (4 boys and 16 girls; age range, 3 to 13 year...

journal_title：Stroke

authors： Kim SK,Yoo JI,Cho BK,Hong SJ,Kim YK,Moon JA,Kim JH,Chung YN,Wang KC

更新日期：2003-12-01 00:00:00

abstract：:Background and Purpose- Intracranial thrombi can be characterized according to their permeability as measured by contrast agent penetration. Thrombus composition and its associated pathogenesis are important factors affecting treatment and secondary prevention. We aimed to explore the histopathologic factors explainin...

journal_title：Stroke

authors： Berndt M,Friedrich B,Maegerlein C,Moench S,Hedderich D,Lehm M,Zimmer C,Straeter A,Poppert H,Wunderlich S,Schirmer L,Oberdieck P,Kaesmacher J,Boeckh-Behrens T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective efficacy of an intravenous formulation of the antioxidant ebselen has been comprehensively assessed with specific regard to conventional quantitative histopathology, subcortical axonal damage, neurological deficit, and principal mechanism of action. METHODS:Transient focal is...

journal_title：Stroke

authors： Imai H,Masayasu H,Dewar D,Graham DI,Macrae IM

更新日期：2001-09-01 00:00:00