Lecithinized superoxide dismutase improves outcomes and attenuates focal cerebral ischemic injury via antiapoptotic mechanisms in rats.

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:MRI characterization of carotid plaque has been studied recently as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a systematic review and meta-analysis to summarize the association of MRI-determined intraplaque hemorrhage, lipid-rich necrotic core, and thinnin...

journal_title：Stroke

authors： Gupta A,Baradaran H,Schweitzer AD,Kamel H,Pandya A,Delgado D,Dunning A,Mushlin AI,Sanelli PC

更新日期：2013-11-01 00:00:00

abstract：:The study of focal central nervous system ischemia has been impeded by the lack of animal models that are both reproducible and simulate human ischemic strokes. To circumvent these problems, we have developed a rabbit spinal cord infarction model. Infarction of the caudal lumbar cord is produced by temporary occlusion...

journal_title：Stroke

authors： Zivin JA,DeGirolami U

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to demonstrate the contribution of axonal remodeling of the corticospinal tract (CST) in the spinal cord to functional outcome after stroke. METHODS:Bilateral pyramidotomy (BPT) or sham-BPT was performed in mice with transgenic yellow fluorescent protein labeling in the CST subjected t...

journal_title：Stroke

authors： Liu Z,Chopp M,Ding X,Cui Y,Li Y

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The durability of carotid endarterectomy (CEA) in young adults with premature carotid atherosclerosis has not been adequately assessed. This study examined the late recurrence and mortality rates in young adults undergoing CEA. METHODS:We studied 42 young patients (mean age, 45.5 +/- 0.5 years) ...

journal_title：Stroke

authors： Valentine RJ,Myers SI,Hagino RT,Clagett GP

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations. METHODS:We evaluated associations of body mass index (BMI), waist-hip ratio (W...

journal_title：Stroke

authors： Zhang X,Shu XO,Gao YT,Yang G,Li H,Zheng W

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Space-occupying brain edema is a life-threatening complication in patients with large middle cerebral artery (MCA) infarction. To determine predictors of this detrimental process, we investigated alterations of extracellular non-transmitter amino acid concentrations in peri-infarct tissue. METHO...

journal_title：Stroke

authors： Bosche B,Dohmen C,Graf R,Neveling M,Staub F,Kracht L,Sobesky J,Lehnhardt FG,Heiss WD

更新日期：2003-12-01 00:00:00

abstract：:We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham oper...

journal_title：Stroke

authors： Hyodo A,Heros RC,Tu YK,Ogilvy C,Graichen R,Lagree K,Korosue K

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Emboli and proinflammatory mediators are suspected of generating cerebral edema after coronary surgery. In contrast to cardiopulmonary bypass (CPB), off-pump coronary artery bypass surgery (OPCAB) reduces microemboli count and proinflammatory mediator release but carries the risk of hemodynamic i...

journal_title：Stroke

authors： Bierbach B,Meier M,Kasper-König W,Heimann A,Alessandri B,Horstick G,Oelert H,Kempski O

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A high incidence of arteriovenous malformations (AVMs) is associated with hereditary hemorrhagic telangiectasia type 1. Endoglin, the gene mutated in this disorder, is expressed at reduced levels on blood vessels of these patients. Since endoglin is a component of the transforming growth factor-b...

journal_title：Stroke

authors： Matsubara S,Bourdeau A,terBrugge KG,Wallace C,Letarte M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke leads to a reduction in bone mineral density, altered calcium homeostasis, and an increase in hip fractures. Vitamin D deficiency is well documented in long-term stroke survivors and is associated with post-stroke hip fractures. Less is known regarding levels in acute stroke. METHODS:We c...

journal_title：Stroke

authors： Poole KE,Loveridge N,Barker PJ,Halsall DJ,Rose C,Reeve J,Warburton EA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In most European societies and in the United States, the percentage of patients ≥80 years has been rising over the past century. The present study was conducted to observe this demographic change and its impact on patients with intracerebral hemorrhage (ICH). METHODS:We reviewed patients' data w...

journal_title：Stroke

authors： Stein M,Misselwitz B,Hamann GF,Scharbrodt W,Schummer DI,Oertel MF

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Rates of development of de novo intracranial aneurysms and of growth of untreated additional aneurysms are largely unknown. We performed MRA in a large patient cohort with coiled aneurysms at 5-year follow-up. METHODS:In 276 patients with coiled intracranial aneurysms and 5±0.5 years of follow-u...

journal_title：Stroke

authors： Ferns SP,Sprengers ME,van Rooij WJ,van den Berg R,Velthuis BK,de Kort GA,Sluzewski M,van Zwam WH,Rinkel GJ,Majoie CB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...

journal_title：Stroke

authors： Larsson SC,Orsini N

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic nervous system diseases affect systemic blood pressure regulation. Patients with autonomic nervous system diseases have consistently larger drops in blood pressure associated with standing than the normal population. Autonomic dysfunction and/or these changes in blood pressure may affec...

journal_title：Stroke

authors： Blaber AP,Bondar RL,Stein F,Dunphy PT,Moradshahi P,Kassam MS,Freeman R

更新日期：1997-09-01 00:00:00

abstract：:The authors report an autopsy case with repeated transient ischemic attacks and subsequent strokes demonstrating evidence of artery-to-artery embolism from thrombi generated in the stenotic middle cerebral artery to the distal cortical branches. This case substantiates the existence of intracranial artery-to-artery em...

journal_title：Stroke

authors： Masuda J,Ogata J,Yutani C,Miyashita T,Yamaguchi T

更新日期：1987-05-01 00:00:00

abstract：:Glycosylated hemoglobin concentration (GHb), which is considered an indication of glycemia over the preceding several months, was examined in 50 patients hospitalized for recent stroke or transient ischemic attacks (TIA), and compared to that in several reference populations. Patients with stroke or TIA had GHb (mean ...

journal_title：Stroke

authors： Riddle MC,Hart J

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Higher proportions of hemorrhagic stroke and lacunar infarction were reported in rural Japan compared with those in Western countries. We examined the relative proportions of stroke subtypes in an urban Japanese city where westernized lifestyles are more common than in rural areas. METHODS:Strok...

journal_title：Stroke

authors： Kitamura A,Nakagawa Y,Sato M,Iso H,Sato S,Imano H,Kiyama M,Okada T,Okada H,Iida M,Shimamoto T

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Motor dysfunction after unilateral deafferentation in primates can be overcome by restraining the unaffected limb. We asked whether a constraint-induced movement (CIM) program could be implemented within 2 weeks after stroke and whether CIM is more effective than traditional upper-extremity (UE) ...

journal_title：Stroke

authors： Dromerick AW,Edwards DF,Hahn M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy (CE) has been shown to be beneficial in patients with symptomatic high-grade (70% to 99%) internal carotid artery stenosis. To achieve this benefit, complications must be kept to a minimum. Complications not associated with the procedure itself, but related to medical condi...

journal_title：Stroke

authors： Paciaroni M,Eliasziw M,Kappelle LJ,Finan JW,Ferguson GG,Barnett HJ

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

journal_title：Stroke

authors： Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

更新日期：2005-10-01 00:00:00

abstract：:In 100 consecutive patients with acute cerebrovascular accident, due to cerebral thrombosis in 72, cerebral hemorrhage in 12, embolus in 6, and subarachnoid hemorrhage in 10, there were 90 who had electrocardiographic abnormalities during the first three days after admission, compared to 50% in a control group. The pa...

journal_title：Stroke

authors： Dimant J,Grob D

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. ...

journal_title：Stroke

authors： Urban PP,Wolf T,Uebele M,Marx JJ,Vogt T,Stoeter P,Bauermann T,Weibrich C,Vucurevic GD,Schneider A,Wissel J

更新日期：2010-09-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study aimed to independently derive an intracerebral hemorrhage grading scale (ICH-GS) for prediction of 3 outcome measures. METHODS:We evaluated 378 patients with primary ICH at hospital arrival and during the next 30 days. Independent predictors were identified by multivariate models of i...

journal_title：Stroke

authors： Ruiz-Sandoval JL,Chiquete E,Romero-Vargas S,Padilla-Martínez JJ,González-Cornejo S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The sensitivity of the brain to brief periods of profound ischemia or prolonged periods of modest ischemia mandates an aggressive approach to acute stroke care. Past studies have shown that many stroke patients do not receive acute care in an urgent and timely fashion. The formation of acute stro...

journal_title：Stroke

authors： Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

journal_title：Stroke

authors： Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although headache is the most common symptom in cerebral venous thrombosis, 5% to 30% of patients do not report headache at baseline. Characteristics of these patients have not been investigated. METHODS:In post hoc analysis of the International Study on Cerebral Vein and Dural Sinus Thrombosis ...

journal_title：Stroke

authors： Coutinho JM,Stam J,Canhão P,Barinagarrementeria F,Bousser MG,Ferro JM,ISCVT Investigators.

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Deep intracerebral hemorrhage (ICH) and lacunar infarcts are the result of small vessel disease, whereas nonlacunar infarcts are often caused by large artery atherosclerosis or cardiac embolism. We hypothesized that patients with deep ICH and lacunar infarcts have similar retinal microvascular si...

journal_title：Stroke

authors： Baker ML,Hand PJ,Liew G,Wong TY,Rochtchina E,Mitchell P,Lindley RI,Hankey GJ,Wang JJ,Multi-Centre Retinal Stroke Study Group.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prophylactic administration of simvastatin has been shown to protect against brain damage and its long-lasting behavioral consequences in neonatal rats. To establish the drug treatment window, we evaluated the effectiveness of simvastatin administered at different intervals before and after strok...

journal_title：Stroke

authors： Balduini W,Mazzoni E,Carloni S,De Simoni MG,Perego C,Sironi L,Cimino M

更新日期：2003-08-01 00:00:00