Cerebral microembolism and the risk of ischemia in asymptomatic high-grade internal carotid artery stenosis.

abstract：BACKGROUND AND PURPOSE:The migratory efficiency of mesenchymal stem cells (MSC) toward cerebral infarct after transplantation is limited. Valproate (VPA) and lithium enhance in vitro migration of MSC by upregulating CXC chemokine receptor 4 and matrix metalloproteinase-9, respectively. Ability of VPA and lithium to pro...

journal_title：Stroke

authors： Tsai LK,Wang Z,Munasinghe J,Leng Y,Leeds P,Chuang DM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A close correlation between B-mode sonography and the histopathology and surface structure of plaque is rarely seen in vivo with high-grade stenoses of the extracranial carotid artery. The goal of this study was to determine whether normalized gray scale analysis and surface analysis of the plaqu...

journal_title：Stroke

authors： Denzel C,Balzer K,Müller KM,Fellner F,Fellner C,Lang W

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this amino acid has been shown to be due to nutritional status and methylenetetrahydrofolate reductase (MTHFR) genotype. METHODS:Under a case-cont...

journal_title：Stroke

authors： McIlroy SP,Dynan KB,Lawson JT,Patterson CC,Passmore AP

更新日期：2002-10-01 00:00:00

abstract：:Regional cerebral blood flow (CBF) was measured (intra-arterial injections of 133Xe) and electroencephalograms (EEG) were recorded periodically before, for two hours during, and for one and one-fourth hours after middle cerebral artery (MCA) occlusion in 20 squirrel monkeys (Saimiri sciureus). A CBF-Paco2 response cur...

journal_title：Stroke

authors： Donley RF,Sundt TM,Anderson RE,Sharbrough FW

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although cerebral penetrating arterioles are main regulators of the brain microcirculation, little is known about the effect of endothelium-derived relaxation factor on these vessels. This study examined the effects of nitric oxide synthase inhibitors on the spontaneous tone of isolated rat cereb...

journal_title：Stroke

authors： Kimura M,Dietrich HH,Dacey RG Jr

更新日期：1994-11-01 00:00:00

abstract：:One hundred and sixteen carotid artery bruits were assessed using quantitative phonoangiography (spectral bruit analysis - SBA). This technique uses the averaged break frequency of the bruit to calculate the diameter of he residual lumen at the site of stenosis. Biplanar contrast arteriography was performed on 43 (37%...

journal_title：Stroke

authors： Knox R,Breslau P,Strandness DE Jr

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Timing of carotid endarterectomy after stroke in a patient with a fixed neurological deficit remains an important but unresolved question. Early surgery has been associated with cerebral hemorrhage and infarct extension. Delayed endarterectomy exposes the patient to recurrent stroke and carotid occlusion. Th...

journal_title：Stroke

authors： Pritz MB

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Posttraumatic stress disorder (PTSD) can be triggered by life-threatening medical events such as strokes and transient ischemic attacks (TIAs). Little is known regarding how PTSD triggered by medical events affects patients' adherence to medications. METHODS:We surveyed 535 participants, age ≥40...

journal_title：Stroke

authors： Kronish IM,Edmondson D,Goldfinger JZ,Fei K,Horowitz CR

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

journal_title：Stroke

authors： Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same tre...

journal_title：Stroke

authors： Kozak A,Ergul A,El-Remessy AB,Johnson MH,Machado LS,Elewa HF,Abdelsaid M,Wiley DC,Fagan SC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Systemic inflammatory response syndrome (SIRS) is a generalized inflammatory state. The primary goal of the study was to determine whether differences exist in outcomes in SIRS and non-SIRS intravenous tissue-type plasminogen activator-treated patients. METHODS:Consecutive patients were retrospe...

journal_title：Stroke

authors： Boehme AK,Kapoor N,Albright KC,Lyerly MJ,Rawal PV,Bavarsad Shahripour R,Alvi M,Houston JT,Sisson A,Beasley TM,Alexandrov AW,Alexandrov AV,Miller DW

更新日期：2013-08-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：:I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...

journal_title：Stroke

authors： Ryding E

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Electrocardiographic abnormalities are common after subarachnoid hemorrhage, but their significance remains uncertain. The aim of this study was to determine whether any specific electrocardiographic abnormalities are independently associated with adverse neurological outcomes. METHODS:This was ...

journal_title：Stroke

authors： Coghlan LA,Hindman BJ,Bayman EO,Banki NM,Gelb AW,Todd MM,Zaroff JG,IHAST Investigators.

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Validation of the Boston criteria for the in vivo diagnosis of cerebral amyloid angiopathy (CAA) is challenging, because noninvasive diagnostic tests do not exist. Hereditary cerebral hemorrhage with amyloidosis-Dutch type is an accepted monogenetic model of CAA and diagnosis can be made with cer...

journal_title：Stroke

authors： van Rooden S,van der Grond J,van den Boom R,Haan J,Linn J,Greenberg SM,van Buchem MA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Leptin is the major adipose hormone that regulates body weight and energy expenditure by activating leptin receptors in the hypothalamus. Leptin receptors are also present in other cell types, and a potent antiapoptotic effect for leptin has recently been reported. We investigated whether leptin ...

journal_title：Stroke

authors： Zhang F,Wang S,Signore AP,Chen J

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an inverse association between dairy food consumption and the incidence of stroke in observational studies. However, it is unknown whether the relationship is causal or, if so, what components in milk are responsible for reducing the incidence of stroke. METHODS:Stroke-prone spontaneous...

journal_title：Stroke

authors： Chiba T,Itoh T,Tabuchi M,Ooshima K,Satou T,Ezaki O

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The reliability of the National Institutes of Health Stroke Scale (NIHSS) has been established through testing its use in live and videotaped patients. This reliability testing has primarily focused on the use of the scale by neurologists. We sought to determine the reliability of the NIHSS as us...

journal_title：Stroke

authors： Goldstein LB,Samsa GP

更新日期：1997-02-01 00:00:00

abstract：:Background and Purpose- Hyperacute assessment and management of patients with stroke, termed code stroke, is a time-sensitive and high-stakes clinical scenario. In the context of the current coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus, the ability to deliver timely and efficacious care ...

journal_title：Stroke

authors： Khosravani H,Rajendram P,Notario L,Chapman MG,Menon BK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Quantitative data on sensory impairment in stroke patients are limited. We measured the perception thresholds for temperature and thermal pain in patients with different lacunar syndromes, correlated the results with clinical and magnetic resonance imaging (MRI) findings, and studied the long-ter...

journal_title：Stroke

authors： Samuelsson M,Samuelsson L,Lindell D

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to further analyze the temporal patterns of onset of intracerebral hemorrhage (ICH) and to determine whether or not subgroups with specific clinical characteristics exhibit different patterns of onset. METHODS:The daily, weekly, and yearly variations in occurrence o...

journal_title：Stroke

authors： Passero S,Reale F,Ciacci G,Zei E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...

journal_title：Stroke

authors： Sirén AL,Liu Y,Feuerstein G,Hallenbeck JM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Glutamate receptor antagonists are protective in animal models of focal cerebral ischemia. Lamotrigine (3,5-diamino-6-[2,3-dichlorophenyl]-1,2,4-triazine) is an anticonvulsant drug that blocks voltage-gated sodium channels and inhibits the ischemia-induced release of glutamate. We describe the ce...

journal_title：Stroke

authors： Smith SE,Meldrum BS

更新日期：1995-01-01 00:00:00

abstract：:As indicated by Barnett, Plum and Walton, a definitive clinical trial to resolve the issue of the effectiveness of carotid endarterectomy is clearly needed. A proposal to foster such a trial, through a moratorium on third-party reimbursement other than for randomized patients, has herein been presented. ...

journal_title：Stroke

authors： Jonas S

更新日期：1986-11-01 00:00:00

abstract：:Background and Purpose- We aimed to define the neuroimaging determinants of poststroke cognitive performance and their relative contributions among a spectrum of magnetic resonance imaging markers, including lesion burden and strategic locations. Methods- We prospectively included patients with stroke from the GRECogV...

journal_title：Stroke

authors： Puy L,Barbay M,Roussel M,Canaple S,Lamy C,Arnoux A,Leclercq C,Mas JL,Tasseel-Ponche S,Constans JM,Godefroy O,GRECogVASC Study Group.

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The consequences of stroke are a major health concern. This study was conducted to compare the health-related quality of life among long-term survivors of stroke with that of the general population. METHODS:Our data are taken from a population-based case-control study of all 6-year survivors of ...

journal_title：Stroke

authors： Hackett ML,Duncan JR,Anderson CS,Broad JB,Bonita R

更新日期：2000-02-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little information is available regarding black-white differences in stroke incidence in young adults. METHODS:Cerebral infarction and intracerebral hemorrhage rates among adults 15 to 44 years of age were studied in Baltimore City and Baltimore County for 1988. Diagnoses were based on neurologi...

journal_title：Stroke

authors： Kittner SJ,McCarter RJ,Sherwin RW,Sloan MA,Stern BJ,Johnson CJ,Buchholz D,Seipp MJ,Price TR

更新日期：1993-12-01 00:00:00

abstract：:Neurogenically caused cardiac arrhythmias and their correlation to lesions within the central nervous system were examined prospectively in 54 patients with spontaneous intracerebral hemorrhage. All patients were examined neurologically daily for 3 weeks, with special attention given to signs of brainstem compression ...

journal_title：Stroke

authors： Stober T,Sen S,Anstätt T,Bette L

更新日期：1988-06-01 00:00:00