Thromboxane synthesis inhibitor in a beagle pup model of perinatal asphyxia.

abstract：BACKGROUND AND PURPOSE:Global cerebral blood flow (CBF) is an important yet largely unknown quantity in the treatment of neurological intensive care patients. Color duplex sonography of the extracranial cerebral arteries can be used to measure global CBF volume directly at the bedside. To establish reference data on gl...

journal_title：Stroke

authors： Scheel P,Ruge C,Petruch UR,Schöning M

更新日期：2000-01-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) activity was measured in 34 patients with acute cerebrovascular disease. The serum level of DBH activity showed its highest value soon after the onset of stroke and then gradually decreased over the next few days. After reaching its lowest level, the DBH activity again showed a sl...

journal_title：Stroke

authors： Kanda T,Gotoh F,Yamamoto M,Sakai F,Takeoka T,Takagi Y

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aim was to explore whether the mismatch in lesion visibility between b1000 and b0 images is an alternative to mismatch between diffusion-weighted imaging and fluid-attenuated inversion recovery imaging as a surrogate marker of stroke age. METHODS:We analyzed patients from the European multic...

journal_title：Stroke

authors： Geraldo AF,Berner LP,Haesebaert J,Chabrol A,Cho TH,Derex L,Hermier M,Louis-Tisserand G,Chamard L,Klaerke Mikkelsen I,Ribe L,Østergaard L,Hjort N,Pedraza S,Thomalla G,Baron JC,Nighoghossian N,Berthèzene Y

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ultrasonographic plaque echolucency has been studied as a stroke risk marker in carotid atherosclerotic disease. We performed a systematic review and meta-analysis to summarize the association between ultrasound-determined carotid plaque echolucency and future ipsilateral stroke risk. METHODS:We...

journal_title：Stroke

authors： Gupta A,Kesavabhotla K,Baradaran H,Kamel H,Pandya A,Giambrone AE,Wright D,Pain KJ,Mtui EE,Suri JS,Sanelli PC,Mushlin AI

更新日期：2015-01-01 00:00:00

abstract：:Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a co...

journal_title：Stroke

authors： Dichgans M,Planas AM,Biessels GJ,van der Worp B,Sudlow C,Norrving B,Lees K,Mattle HP

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...

journal_title：Stroke

authors： Achrol AS,Pawlikowska L,McCulloch CE,Poon KY,Ha C,Zaroff JG,Johnston SC,Lee C,Lawton MT,Sidney S,Marchuk DA,Kwok PY,Young WL,UCSF BAVM Study Project.

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Follow-up imaging is often performed in intracranial aneurysms that are not treated. We performed a systematic review and meta-analysis on patient- and aneurysm-specific risk factors for aneurysm growth. METHODS:We searched EMBASE and MEDLINE for cohort studies describing risk factors for aneury...

journal_title：Stroke

authors： Backes D,Rinkel GJ,Laban KG,Algra A,Vergouwen MD

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was...

journal_title：Stroke

authors： Sung YF,Lu CC,Lee JT,Hung YJ,Hu CJ,Jeng JS,Chiou HY,Peng GS

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:The aim of the present study was to investigate the diagnostic potential of contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) in otherwise ultrasound-refractory acute stroke patients with an ischemia in the territory of the middle cerebral artery (MCA). Furthermore, correlations of CE-TC...

journal_title：Stroke

authors： Postert T,Braun B,Meves S,Köster O,Przuntek H,Weber S,Büttner T

更新日期：1999-09-01 00:00:00

abstract：:Regional cerebral blood flow (CBF) was measured (intra-arterial injections of 133Xe) and electroencephalograms (EEG) were recorded periodically before, for two hours during, and for one and one-fourth hours after middle cerebral artery (MCA) occlusion in 20 squirrel monkeys (Saimiri sciureus). A CBF-Paco2 response cur...

journal_title：Stroke

authors： Donley RF,Sundt TM,Anderson RE,Sharbrough FW

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aims of this study were to determine the magnitude of the increase in fracture risk after hospitalization for stroke, and in particular to determine the time course of this risk. METHODS:The records of the Swedish register of patients admitted during 1987-1996 were examined to identify all p...

journal_title：Stroke

authors： Kanis J,Oden A,Johnell O

更新日期：2001-03-01 00:00:00

abstract：:With the use of a new ultrasonic volume flow meter (VFM), over 8000 measurements of common carotid blood flow were made in 120 normal control subjects and 550 patients with various neurological disease. The accuracy of the flow meter in measuring blood flow on an experimental model ranged from 93 to 97%. In normal sub...

journal_title：Stroke

authors： Uematsu S,Yang A,Preziosi TJ,Kouba R,Toung TJ

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Genetic enzyme variation and vitamin intake are important determinants of blood homocyst(e)ine levels. The prevalence of common genetic polymorphisms influencing homocyst(e)ine levels varies by race, and vitamin intake varies by socioeconomic status. Therefore, we examined the effect of vitamin i...

journal_title：Stroke

authors： Kittner SJ,Giles WH,Macko RF,Hebel JR,Wozniak MA,Wityk RJ,Stolley PD,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Malinow MR

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased cortical microvascularization has been proposed to be a Moyamoya disease (MMD)-specific characteristic. It was the aim of our study to characterize the anatomic pattern and microhemodynamics of cortical microvascularization in MMD. METHODS:Intraoperative indocyanine green videoangiogra...

journal_title：Stroke

authors： Czabanka M,Peña-Tapia P,Schubert GA,Woitzik J,Vajkoczy P,Schmiedek P

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We compared two-dimensional time-of-flight magnetic resonance angiography (MRA) and duplex ultrasonography with arteriography for the detection of 70% to 99% stenoses at the carotid artery bifurcation (ie, surgical disease according to findings of the North American Carotid Endarterectomy Trial)....

journal_title：Stroke

authors： Mittl RL Jr,Broderick M,Carpenter JP,Goldberg HI,Listerud J,Mishkin MM,Berkowitz HD,Atlas SW

更新日期：1994-01-01 00:00:00

abstract：:Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

journal_title：Stroke

authors： Fiedler VB,Seuter F,Perzborn E

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk-factor modeling has been proposed to identify patients with carotid stenosis who will most benefit from surgery. Validation by independent institutions performing carotid endarterectomy is necessary to determine the applicability of such models to the individual patient. METHODS:A series of...

journal_title：Stroke

authors： Barth A,Bassetti C

更新日期：2003-02-01 00:00:00

abstract：:Results from 1,039 combined cervical and transcranial Doppler examinations are reported. Satisfactory transcranial signals were not found in 2.7% of the cases. Compared with angiography, the accuracy of transcranial criteria in assessing collateral flow over the circle of Willis was 94 and 88% for anterior and posteri...

journal_title：Stroke

authors： Grolimund P,Seiler RW,Aaslid R,Huber P,Zurbruegg H

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A low ankle-brachial blood pressure index (ABI) is an established risk marker for cardiovascular disease and mortality in the general population, but little is known about its prognostic value in individuals with acute ischemic stroke or transient ischemic attack (TIA). METHODS:An inception coho...

journal_title：Stroke

authors： Busch MA,Lutz K,Röhl JE,Neuner B,Masuhr F

更新日期：2009-12-01 00:00:00

abstract：:We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...

journal_title：Stroke

authors： Yokota M,Tani E,Maeda Y

更新日期：1989-04-01 00:00:00

abstract：:Before surgery, we evaluated major intracranial collateral pathways using transcranial Doppler ultrasonography (TCD) in 50 patients who then underwent carotid endarterectomy with concurrent multimodality cerebral monitoring. Patients were grouped with respect to collateral pathways demonstrated preoperatively by TCD: ...

journal_title：Stroke

authors： Schneider PA,Ringelstein EB,Rossman ME,Dilley RB,Sobel DF,Otis SM,Bernstein EF

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Results from large multicenter studies have shown that carotid endarterectomy, performed with low perioperative morbidity and mortality, is beneficial for patients with symptomatic carotid stenosis > or = 70% as calculated according to strict angiographic criteria. To apply these results in clini...

journal_title：Stroke

authors： Chang YJ,Golby AJ,Albers GW

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of tissue-type plasminogen activator on functional outcome decreases progressively over time. However, given the differential pattern of arterial occlusion, stroke severity, and speed of ischemic lesion growth among candidates for reperfusion, the time window should be adjusted accordi...

journal_title：Stroke

authors： Muchada M,Rubiera M,Rodriguez-Luna D,Pagola J,Flores A,Kallas J,Sanjuan E,Meler P,Alvarez-Sabin J,Ribo M,Molina CA

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-dose human albumin (ALB) is robustly neuroprotective in rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of ALB therapy in ischemic stroke. We analyzed the data for preliminary evidence of treatment efficacy. METHODS:Eighty-two subjects with acute isc...

journal_title：Stroke

authors： Palesch YY,Hill MD,Ryckborst KJ,Tamariz D,Ginsberg MD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The shape and exact size of lacunar infarcts have been investigated only postmortem. Recent imaging techniques based on triangulation and connectivity can now be used for 3D segmentation of cerebral lesions. The shape and size of lacunar infarcts was investigated using these techniques in 10 cere...

journal_title：Stroke

authors： Hervé D,Mangin JF,Molko N,Bousser MG,Chabriat H

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS:In vitro studies involved serum deprivation of rat embryonic cortical neurons and ...

journal_title：Stroke

authors： Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by...

journal_title：Stroke

authors： Arima H,Huang Y,Wang JG,Heeley E,Delcourt C,Parsons M,Li Q,Neal B,Chalmers J,Anderson C,INTERACT1 Investigators.

更新日期：2012-08-01 00:00:00

abstract：:Correlations between changes in regional, cortical, cerebral blood flow (rCBF) and histological changes in the corresponding brain regions were examined following middle cerebral arterial occlusion in 24 cats. In all animals, the duration of arterial occlusion was 2 hours followed by 2 hours of recirculation. The anim...

journal_title：Stroke

authors： Tamura A,Asano T,Sano K

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is no...

journal_title：Stroke

authors： Söderholm M,Zia E,Hedblad B,Engström G

更新日期：2012-10-01 00:00:00