Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke.

abstract：BACKGROUND AND PURPOSE:Differences exist between European countries in the proportion of patients who die or become dependent after stroke. The aim of the present study was to identify differences in the use of time by stroke patients in 4 rehabilitation centers in 4 European countries. METHODS:In each of the 4 center...

journal_title：Stroke

authors： De Wit L,Putman K,Dejaeger E,Baert I,Berman P,Bogaerts K,Brinkmann N,Connell L,Feys H,Jenni W,Kaske C,Lesaffre E,Leys M,Lincoln N,Louckx F,Schuback B,Schupp W,Smith B,De Weerdt W

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Matrix metalloproteinases (MMPs) and cysteine proteases (calpain and cathepsin B) play an important role in cell death and are upregulated after focal cerebral ischemia. Because there is a significant interaction between MMP-9 with calpain and cathepsin B, we investigated the role of E64d (a calp...

journal_title：Stroke

authors： Tsubokawa T,Solaroglu I,Yatsushige H,Cahill J,Yata K,Zhang JH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Findings on transesophageal echocardiography (TEE) after ischemic stroke predict recurrent embolic events and prompt therapy; however, the additive predictive power of TEE findings on long-term mortality is unknown. Our goal was to study the impact of TEE findings on all cause mortality in ischem...

journal_title：Stroke

authors： Ward RP,Don CW,Furlong KT,Lang RM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by...

journal_title：Stroke

authors： Arima H,Huang Y,Wang JG,Heeley E,Delcourt C,Parsons M,Li Q,Neal B,Chalmers J,Anderson C,INTERACT1 Investigators.

更新日期：2012-08-01 00:00:00

abstract：:Background and Purpose- Preterm neonates with intraventricular hemorrhage (IVH) are at risk for posthemorrhagic hydrocephalus and poor neurological outcomes. Iron has been implicated in ventriculomegaly, hippocampal injury, and poor outcomes following IVH. We hypothesized that levels of cerebrospinal fluid blood break...

journal_title：Stroke

authors： Mahaney KB,Buddhala C,Paturu M,Morales D,Limbrick DD Jr,Strahle JM

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to determine the 30-day mortality and morbidity of intracerebral hemorrhage in a large metropolitan population and to determine the most important predictors of 30-day outcome. METHODS:We reviewed the medical records and computed tomographic films for all cases of spont...

journal_title：Stroke

authors： Broderick JP,Brott TG,Duldner JE,Tomsick T,Huster G

更新日期：1993-07-01 00:00:00

abstract：:Atrial septal aneurysm is an uncommon occult cardiac source of cerebral embolism. It is usually asymptomatic, and clinical cardiologic examination and electrocardiography fail to reveal its presence. We report a case of a 34-year-old woman with sudden right hemiplegia and aphasia from occlusion of the left carotid sip...

journal_title：Stroke

authors： Di Pasquale G,Andreoli A,Grazi P,Dominici P,Pinelli G

更新日期：1988-05-01 00:00:00

abstract：:Background and Purpose- The impact of a mobile stroke unit (MSU) on access to intraarterial thrombectomy (IAT) is a prespecified BEST-MSU substudy (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services). On the MSU, IAT decision-making steps, su...

journal_title：Stroke

authors： Czap AL,Grotta JC,Parker SA,Yamal JM,Bowry R,Sheth SA,Rajan SS,Hwang H,Singh N,Bratina P,Bryndziar T,Alexandrov AV,Alexandrov AW,Dusenbury W,Swatzell V,Jones W,Ackerson K,Schimpf B,Wright P,Jagolino-Cole AL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective role of mild therapeutic hypothermia was established in animal models of cerebral ischemia. Still, several issues, including optimal target temperature, remain unclear. The optimal depth of hypothermia in a rat model of focal cerebral ischemia was investigated. METHODS:Eighty...

journal_title：Stroke

authors： Kollmar R,Blank T,Han JL,Georgiadis D,Schwab S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic stroke has a strong familial component to risk. The Siblings With Ischemic Stroke Study (SWISS) is a genome-wide, family-based analysis that included use of imputed genotypes. The Siblings With Ischemic Stroke Study was conducted to examine the associations between single-nucleotide poly...

journal_title：Stroke

authors： Meschia JF,Nalls M,Matarin M,Brott TG,Brown RD Jr,Hardy J,Kissela B,Rich SS,Singleton A,Hernandez D,Ferrucci L,Pearce K,Keller M,Worrall BB,Siblings With Ischemic Stroke Study Investigators.

更新日期：2011-10-01 00:00:00

abstract：:We have studied a new high-affinity competitive N-methyl-D-aspartate antagonist, D-CPP-ene (SDZ-EAA 494), in two models of focal cerebral ischemia. In the cat middle cerebral artery occlusion model (6 hours' survival), pretreatment with D-CPP-ene reduced infarct size by 64% (15 mg/kg dose) and 60% (4.5 mg/kg dose). Th...

journal_title：Stroke

authors： Bullock R,McCulloch J,Graham DI,Lowe D,Chen MH,Teasdale GM

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cannabidiol has been reported to be a neuroprotectant, but the neuroprotective mechanism of cannabidiol remains unclear. We studied the neuroprotective mechanism of cannabidiol in 4-hour middle cerebral artery (MCA) occlusion mice. METHODS:Male MCA occluded mice were treated with cannabidiol, ab...

journal_title：Stroke

authors： Mishima K,Hayakawa K,Abe K,Ikeda T,Egashira N,Iwasaki K,Fujiwara M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The decision to proceed with surgery in cerebellar infarct with mass effect (CIMASS) in deteriorating patients is based on clinical features. The potential role of neuroimaging in predicting deterioration has not been systematically studied. In this study we determine the role of neuroimaging in ...

journal_title：Stroke

authors： Koh MG,Phan TG,Atkinson JL,Wijdicks EF

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral sinovenous thrombosis is a rare disease with severe neurological sequelae. The aim of this retrospective multicenter study was to investigate the clinical course, possible risk factors, and outcome of a cohort of neonatal patients with sinovenous thrombosis and, second, to estimate the i...

journal_title：Stroke

authors： Berfelo FJ,Kersbergen KJ,van Ommen CH,Govaert P,van Straaten HL,Poll-The BT,van Wezel-Meijler G,Vermeulen RJ,Groenendaal F,de Vries LS,de Haan TR

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The presence of known restriction fragment length polymorphisms in the apoprotein A-I-C-III gene cluster, which encodes their respective apoproteins, was investigated using the restriction enzymes Sac I and Pst I to determine the potential role of genetic variations for stroke risk in an American...

journal_title：Stroke

authors： Kasturi R,Yatsu FM,Alam R,Rogers S

更新日期：1992-09-01 00:00:00

abstract：:Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experienc...

journal_title：Stroke

authors： Yenari MA,Hemmen TM

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Genetic factors involved in the pathogenesis of primary intracerebral hemorrhage (PICH) remain unknown. One of the candidate genes is SERPINA3. Results of a Spanish study suggested that TT genotype of the A/T SERPINA3 polymorphism in the signal peptide sequence was a risk factor for PICH in normo...

journal_title：Stroke

authors： Pera J,Slowik A,Dziedzic T,Szczudlik A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies suggest that the management of coronary artery disease differs for women compared with men. We examined this issue for ischemic cerebrovascular disease. METHODS:We reviewed the use of angiography and carotid endarterectomy among patients discharged from Connecticut hospitals dur...

journal_title：Stroke

authors： Patrick SJ,Concato J,Viscoli C,Chyatte D,Brass LM

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. METHODS:A total of 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based on smoking status at 2 different time points (1990 and 1992), were followed from 1992 to 2001 fo...

journal_title：Stroke

authors： Song YM,Cho HJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Milk fat globule-EGF factor-8 (MFGE8) has been reported to be neuroprotective in ischemic stroke. However, the effects of MFGE8 in early brain injury after subarachnoid hemorrhage (SAH) have not been investigated. We investigated the role of MFGE8 in early brain injury and the potential mechanism...

journal_title：Stroke

authors： Liu F,Hu Q,Li B,Manaenko A,Chen Y,Tang J,Guo Z,Tang J,Zhang JH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sulcal effacement with preserved underlying gray-white matter junction (isolated sulcal effacement [ISE]) in acute ischemic stroke may not represent irreversible parenchymal injury. We aimed to evaluate the frequency and significance of ISE in patients with large vessel occlusion acute ischemic s...

journal_title：Stroke

authors： Haussen DC,Lima A,Frankel M,Anderson A,Belagaje S,Nahab F,Rangaraju S,Nogueira RG

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because the diagnosis and treatment of carotid artery disease may reduce the rate of stroke, the aim of this study was to determine whether a diet intervention was associated with incident carotid artery disease. METHODS:Participants were 48 835 postmenopausal women aged 50 to 79 years who were ...

journal_title：Stroke

authors： Allison MA,Aragaki A,Eaton C,Li W,Van Horn L,Daviglus ML,Berger JS

更新日期：2014-06-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (cSVD) is the major vascular cause of cognitive decline and dementia. The pathogenesis of cSVD remains largely unknown, although several studies suggest a role for systemic inflammation. In certain pathophysiological situations, monocytes can reprogram toward a lon...

journal_title：Stroke

authors： Noz MP,Ter Telgte A,Wiegertjes K,Joosten LAB,Netea MG,de Leeuw FE,Riksen NP

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 6% to 9% of patients with subarachnoid hemorrhage (SAH), familial aggregation occurs; truly familial cases carry a worse prognosis than sporadic cases and raise the question of screening. If relatives have died from SAH, the family history is often the only available clue to the diagnosis, but...

journal_title：Stroke

authors： Bromberg JE,Rinkel GJ,Algra A,Greebe P,Beldman T,van Gijn J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...

journal_title：Stroke

authors： Olivot JM,Albucher JF,Guenego A,Thalamas C,Mlynash M,Rousseau V,Drif A,Christensen S,Sommet A,Viguier A,Darcourt J,Calvière L,Menegon P,Raposo N,Januel AC,Bonneville F,Tourdias T,Mazighi M,Sibon I,Albers GW,Cognar

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Depression after stroke is common. Like stroke, transient ischemic attack (TIA) is a manifestation of long-term atherosclerotic damage to the brain. However, the risk of depression developing after a TIA is uncertain. We studied whether TIA increases the risk of incident late-life depression. ME...

journal_title：Stroke

authors： Luijendijk HJ,Stricker BH,Wieberdink RG,Koudstaal PJ,Hofman A,Breteler MM,Tiemeier H

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The incidence of subarachnoid hemorrhage (SAH) has been investigated in many studies. A recent study in Izumo, Japan, indicates that the incidence of SAH is as high as that in Finland. The purpose of this study was to confirm the high incidence of SAH in Japan. METHODS:The incidence rate of SAH ...

journal_title：Stroke

authors： Ohkuma H,Fujita S,Suzuki S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke during pregnancy is an emerging concern. Although females undergo many physiological, endocrine, and neurological alterations during pregnancy, the consequences of such changes on outcome after stroke are unclear. It is predicted that increases in steroid hormones observed during pregnancy...

journal_title：Stroke

authors： Spencer SJ,Galic MA,Tsutsui M,Pittman QJ,Mouihate A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aneurysmal subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality rate and severe disability. Longitudinal studies investigating health-economic costs in SAH are scare and only one of them analyzed cost-driving factors. The objective was to evaluate first-year costs in G...

journal_title：Stroke

authors： Dodel R,Winter Y,Ringel F,Spottke A,Gharevi N,Müller I,Klockgether T,Schramm J,Urbach H,Meyer B

更新日期：2010-12-01 00:00:00