Importance of cerebral collateral pathways during carotid endarterectomy.


:Before surgery, we evaluated major intracranial collateral pathways using transcranial Doppler ultrasonography (TCD) in 50 patients who then underwent carotid endarterectomy with concurrent multimodality cerebral monitoring. Patients were grouped with respect to collateral pathways demonstrated preoperatively by TCD: Group 1, good collateralization with an anterior and/or posterior communicating artery ipsilateral to the operative carotid lesion (29 patients, 58%); Group 2, collateral pathways present but impeded by other proximal stenoses (nine patients, 18%); and Group 3, no collateralization identified (nine patients, 18%). Three patients (6%) could not be classified. TCD identified major collateral pathways with a sensitivity of 89% and a specificity of 80% when compared with arteriography. During carotid endarterectomy mean middle cerebral artery velocity, pulsatility index, and stump pressure were higher and the decrease in middle cerebral artery velocity with extracranial carotid artery cross clamping was significantly less among Group 1 patients than among Group 2 and 3 patients (p less than 0.05 for both groups). Group 1 patients required fewer intraoperative carotid artery shunts and developed fewer ischemic electroencephalographic abnormalities than did patients in Groups 2 and 3 (p less than 0.05 for both groups). TCD assessment of cerebral collateralization helps predict hemodynamic consequences of cross clamping during carotid endarterectomy.






Schneider PA,Ringelstein EB,Rossman ME,Dilley RB,Sobel DF,Otis SM,Bernstein EF




Has Abstract


1988-11-01 00:00:00














  • Biosynthesis of leukotrienes in canine cerebral vasospasm.

    abstract::We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...


    pub_type: 杂志文章


    authors: Yokota M,Tani E,Maeda Y

    更新日期:1989-04-01 00:00:00

  • Contrast-enhanced transcranial color-coded sonography in acute hemispheric brain infarction.

    abstract:PURPOSE:The aim of the present study was to investigate the diagnostic potential of contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) in otherwise ultrasound-refractory acute stroke patients with an ischemia in the territory of the middle cerebral artery (MCA). Furthermore, correlations of CE-TC...


    pub_type: 杂志文章


    authors: Postert T,Braun B,Meves S,Köster O,Przuntek H,Weber S,Büttner T

    更新日期:1999-09-01 00:00:00

  • A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes.

    abstract:BACKGROUND AND PURPOSE:There is debate regarding the approach for analysis of modified Rankin scale scores, the most common functional outcome scale used in acute stroke trials. METHODS:We propose to use tests to assess treatment differences addressing the metric, "if a patient is chosen at random from each treatment ...


    pub_type: 杂志文章


    authors: Howard G,Waller JL,Voeks JH,Howard VJ,Jauch EC,Lees KR,Nichols FT,Rahlfs VW,Hess DC

    更新日期:2012-03-01 00:00:00

  • Comparative Effectiveness of Rivaroxaban, Apixaban, and Warfarin in Atrial Fibrillation Patients With Polypharmacy.

    abstract:BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...


    pub_type: 杂志文章


    authors: Mentias A,Heller E,Vaughan Sarrazin M

    更新日期:2020-07-01 00:00:00

  • Remote Ischemic Conditioning May Improve Outcomes of Patients With Cerebral Small-Vessel Disease.

    abstract:BACKGROUND AND PURPOSE:We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease. METHODS:Thirty patients with cerebral small-vessel disease-related mild cognitive impairment were enrolled in this prospective, randomized controlled study for 1 year. Besides ...


    pub_type: 杂志文章,随机对照试验


    authors: Wang Y,Meng R,Song H,Liu G,Hua Y,Cui D,Zheng L,Feng W,Liebeskind DS,Fisher M,Ji X

    更新日期:2017-11-01 00:00:00

  • Periprocedural Myocardial Infarction After Carotid Endarterectomy and Stenting: Systematic Review and Meta-Analysis.

    abstract:BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) is associated with higher risk of periprocedural stroke and death when compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small, and ...


    pub_type: 杂志文章,meta分析,评审


    authors: Boulanger M,Camelière L,Felgueiras R,Berger L,Rerkasem K,Rothwell PM,Touzé E

    更新日期:2015-10-01 00:00:00

  • Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease.

    abstract:BACKGROUND AND PURPOSE:The watershed cortical areas are the first to be deprived of sufficient blood flow in the event of cerebral hypoperfusion and will be the sites of watershed microinfarcts. Cerebral hypoperfusion is associated with Alzheimer disease (AD), but information regarding the occurrence of watershed corti...


    pub_type: 杂志文章


    authors: Suter OC,Sunthorn T,Kraftsik R,Straubel J,Darekar P,Khalili K,Miklossy J

    更新日期:2002-08-01 00:00:00

  • Enhanced in vivo platelet activation in subtypes of ischemic stroke.

    abstract::It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequenc...


    pub_type: 杂志文章


    authors: Shah AB,Beamer N,Coull BM

    更新日期:1985-07-01 00:00:00

  • An additional monitoring of regional cerebral oxygen saturation to HMPAO SPECT study during balloon test occlusion.

    abstract:BACKGROUND AND PURPOSE:To increase the reliability of 99mTc-hexamethyl propyleneamine oxime (HMPAO) single photon emission computed tomography (SPECT) study in the evaluation of hemodynamic change with balloon test occlusion (BTO) of the internal carotid artery, we attempted to clarify the usefulness of additional moni...


    pub_type: 杂志文章


    authors: Kaminogo M,Ochi M,Onizuka M,Takahata H,Shibata S

    更新日期:1999-02-01 00:00:00

  • Fish consumption and stroke in men. 30-year findings of the Chicago Western Electric Study.

    abstract:BACKGROUND AND PURPOSE:Evidence of a relationship of fish intake to stroke incidence or mortality is weak. This report examines the association of fish consumption with stroke. METHODS:A cohort of 2107 men aged 40 to 55 years from the Chicago Western Electric Study who were free of coronary heart disease and stroke th...


    pub_type: 杂志文章


    authors: Orencia AJ,Daviglus ML,Dyer AR,Shekelle RB,Stamler J

    更新日期:1996-02-01 00:00:00

  • Incidence and causes of strokes associated with pregnancy and puerperium. A study in public hospitals of Ile de France. Stroke in Pregnancy Study Group.

    abstract:BACKGROUND AND PURPOSE:The incidence, causes, and prognosis of nonhemorrhagic strokes and intraparenchymal hemorrhages occurring in association with pregnancy or puerperium are poorly understood. METHODS:We carried out a retrospective (1989 through 1991) and prospective (1992) study in 63 public maternities (348,295 d...


    pub_type: 杂志文章


    authors: Sharshar T,Lamy C,Mas JL

    更新日期:1995-06-01 00:00:00

  • Stroke in Commercial Flights.

    abstract:BACKGROUND AND PURPOSE:Stroke on board aircraft has been reported in retrospective case series, mainly focusing on economy class stroke syndrome. Data on the actual incidence, pathogenesis, and prognosis of stroke in commercial flights are lacking. METHODS:A prospective registry was designed to include all consecutive...


    pub_type: 杂志文章


    authors: Álvarez-Velasco R,Masjuan J,DeFelipe A,Corral I,Estévez-Fraga C,Crespo L,Alonso-Cánovas A

    更新日期:2016-04-01 00:00:00

  • Statins in stroke prevention and carotid atherosclerosis: systematic review and up-to-date meta-analysis.

    abstract:BACKGROUND AND PURPOSE:Previously published meta-analyses exploring the effect of statins on stroke incidence included 20,000 patients and found a 2% to 30% risk reduction. It is not clear whether this is attributable to low-density lipoprotein-cholesterol (LDL-C) reduction. Statin trials have now included >90,000 pati...


    pub_type: 杂志文章,meta分析,评审


    authors: Amarenco P,Labreuche J,Lavallée P,Touboul PJ

    更新日期:2004-12-01 00:00:00

  • Do Clinicians Overestimate the Severity of Intracerebral Hemorrhage?

    abstract::Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...


    pub_type: 杂志文章


    authors: Tilling EJ,El Tawil S,Muir KW

    更新日期:2019-02-01 00:00:00

  • Effects of surgical revascularization on cerebral oxygen metabolism in patients with Moyamoya disease: an 15O-gas positron emission tomographic study.

    abstract:BACKGROUND AND PURPOSE:This prospective study was aimed to evaluate the effects of surgical revascularization on cerebral oxygen metabolism in moyamoya disease. METHODS:This study included totally 69 hemispheres of 42 patients who underwent superficial temporal artery to middle cerebral artery anastomosis and indirect...


    pub_type: 杂志文章


    authors: Kuroda S,Kashiwazaki D,Hirata K,Shiga T,Houkin K,Tamaki N

    更新日期:2014-09-01 00:00:00

  • Left atrial enlargement and stroke recurrence: the Northern Manhattan Stroke Study.

    abstract:BACKGROUND AND PURPOSE:Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences. M...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: Yaghi S,Moon YP,Mora-McLaughlin C,Willey JZ,Cheung K,Di Tullio MR,Homma S,Kamel H,Sacco RL,Elkind MS

    更新日期:2015-06-01 00:00:00

  • Sex differences in US mortality rates for stroke and stroke subtypes by race/ethnicity and age, 1995-1998.

    abstract:BACKGROUND AND PURPOSE:Ischemic stroke accounts for 70% to 80% of all strokes, but intracerebral and subarachnoid hemorrhagic strokes have greater fatality. Age-standardized death rates from overall stroke are higher among men than women, but little is known about sex differences in stroke subtype mortality by race/eth...


    pub_type: 杂志文章


    authors: Ayala C,Croft JB,Greenlund KJ,Keenan NL,Donehoo RS,Malarcher AM,Mensah GA

    更新日期:2002-05-01 00:00:00

  • CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.

    abstract:BACKGROUND AND PURPOSE:Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor inhibition has been hypothesized to provide neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models of a variety of compounds with varying selectivity for AMPA over other...


    pub_type: 杂志文章


    authors: Menniti FS,Buchan AM,Chenard BL,Critchett DJ,Ganong AH,Guanowsky V,Seymour PA,Welch WM

    更新日期:2003-01-01 00:00:00

  • One-year outcome after cerebral infarction in whites, blacks, and Hispanics.

    abstract::Little is known about outcome after cerebral infarction for different ethnic groups. Of 590 stroke patients hospitalized from 1983 to 1986 at the Neurological Institute, cerebral infarction over age 39 years occurred in 135 whites, 177 blacks, and 82 Hispanics. Outcome after cerebral infarction differed by ethnicity. ...


    pub_type: 杂志文章


    authors: Sacco RL,Hauser WA,Mohr JP,Foulkes MA

    更新日期:1991-03-01 00:00:00

  • Effects of the novel thromboxane antagonist Bay U 3405 on experimental coronary artery disease.

    abstract::Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...


    pub_type: 杂志文章


    authors: Fiedler VB,Seuter F,Perzborn E

    更新日期:1990-12-01 00:00:00

  • Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest.

    abstract:BACKGROUND AND PURPOSE:Lamotrigine (LTG) is an anticonvulsant drug whose mechanism of action may involve the inhibition of glutamate release by blocking voltage-dependent sodium channels. Glutamate neurotoxicity may contribute to cerebral ischemic damage after recovery from cardiac arrest. Thus, LTG may prevent the bra...


    pub_type: 杂志文章


    authors: Crumrine RC,Bergstrand K,Cooper AT,Faison WL,Cooper BR

    更新日期:1997-11-01 00:00:00

  • Brain imaging and cognitive predictors of stroke and Alzheimer disease in the Framingham Heart Study.

    abstract:BACKGROUND AND PURPOSE:Exposure to vascular risk factors has a gradual deleterious effect on brain MRI and cognitive measures. We explored whether a pattern of these measures exists that predicts stroke and Alzheimer disease (AD) risk. METHODS:A cognitive battery was administered to 1679 dementia and stroke-free Frami...


    pub_type: 临床试验,杂志文章


    authors: Weinstein G,Beiser AS,Decarli C,Au R,Wolf PA,Seshadri S

    更新日期:2013-10-01 00:00:00

  • Assessment of cerebral autoregulation using carotid artery compression.

    abstract:BACKGROUND AND PURPOSE:A simple method of testing cerebral autoregulation by observing transcranial Doppler changes in middle cerebral artery flow velocity (FV) during a brief ipsilateral carotid artery compression (the transient hyperemic response test) was studied in 11 normal healthy volunteers. The aim of this stud...


    pub_type: 杂志文章


    authors: Smielewski P,Czosnyka M,Kirkpatrick P,McEroy H,Rutkowska H,Pickard JD

    更新日期:1996-12-01 00:00:00

  • Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans.

    abstract:BACKGROUND AND PURPOSE:A precise definition of genetic factors responsible for common forms of stroke is still lacking. The purpose of the present study was to investigate the contributory role of the genes encoding atrial natriuretic peptide (ANP) and type A natriuretic peptide receptor (NPRA) in humans' susceptibilit...


    pub_type: 杂志文章


    authors: Rubattu S,Stanzione R,Di Angelantonio E,Zanda B,Evangelista A,Tarasi D,Gigante B,Pirisi A,Brunetti E,Volpe M

    更新日期:2004-04-01 00:00:00

  • Arterial stiffness, cognitive decline, and risk of dementia: the Rotterdam study.

    abstract:BACKGROUND AND PURPOSE:Arterial stiffness is associated with an increased risk of myocardial infarction and stroke, independent of classical vascular risk factors. Vascular factors and stroke are associated with cognitive function and dementia. We examined whether arterial stiffness was independently associated with co...


    pub_type: 杂志文章


    authors: Poels MM,van Oijen M,Mattace-Raso FU,Hofman A,Koudstaal PJ,Witteman JC,Breteler MM

    更新日期:2007-03-01 00:00:00

  • Deferral of Consent in Acute Stroke Trials.

    abstract::Background and Purpose- The ESCAPE trial (The Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) was a multicentre, randomized controlled trial of endovascular thrombectomy versus standard care for patients with acute ischemic strok...


    pub_type: 杂志文章


    authors: Shamy MCF,Dewar B,Chevrier S,Wang CQ,Page S,Goyal M,Demchuk AM,Hill MD

    更新日期:2019-04-01 00:00:00

  • Moyamoya disease in Europeans.

    abstract:BACKGROUND AND PURPOSE:We describe the clinical, diagnostic, and outcome features of a cohort of white patients with idiopathic moyamoya disease treated in a German institution. METHODS:Our cohort included 21 white patients with moyamoya disease. Clinical and diagnostic features were obtained by retrospective chart re...


    pub_type: 杂志文章


    authors: Kraemer M,Heienbrok W,Berlit P

    更新日期:2008-12-01 00:00:00

  • Characteristics and survival of patients with brain stem infarction.

    abstract::A retrospective study of 141 patients whith ischemic brain stem infarction admitted to the Department of Neurology, University of Helsinki, during 1966 to 1973 was performed. The patients were contacted by mail in January and February, 1974; in case of death, the death certificates were procured. The follow-up period ...


    pub_type: 杂志文章


    authors: Fogelhol R,Aho K

    更新日期:1975-05-01 00:00:00

  • Thrombolysis-related hemorrhagic infarction: a marker of early reperfusion, reduced infarct size, and improved outcome in patients with proximal middle cerebral artery occlusion.

    abstract:BACKGROUND AND PURPOSE:The role of early and delayed recanalization after thrombolysis in the development of hemorrhagic transformation (HT) subtypes remains uncertain. We sought to explore the association between the timing of recanalization and HT risk in patients with proximal middle cerebral artery (MCA) occlusion ...


    pub_type: 临床试验,杂志文章


    authors: Molina CA,Alvarez-Sabín J,Montaner J,Abilleira S,Arenillas JF,Coscojuela P,Romero F,Codina A

    更新日期:2002-06-01 00:00:00

  • Carotid intima-media thickness is different in large- and small-vessel ischemic stroke: the SMART study.

    abstract:BACKGROUND AND PURPOSE:The role of athersclerosis in the difference between the pathogenesis of large-vessel disease (LVD) and small-vessel disease (SVD) is a matter of debate. Common carotid artery intima-media thickness (CCA IMT) is a marker of atherosclerosis. Our aim was to compare CCA IMT between SVD and LVD patie...


    pub_type: 杂志文章


    authors: Pruissen DM,Gerritsen SA,Prinsen TJ,Dijk JM,Kappelle LJ,Algra A,SMART Study Group.

    更新日期:2007-04-01 00:00:00