Pulse pressure in youth and carotid intima-media thickness in adulthood: the cardiovascular risk in young Finns study.

Abstract:

BACKGROUND AND PURPOSE:Large pulse pressure associates with atherosclerosis, but it is unclear if it contributes to the development of atherosclerosis or if atherosclerosis leads to pulse pressure widening. We examined whether exposure to large pulse pressure in childhood predicts carotid artery intima-media thickness in adulthood. METHODS:Carotid intima-media thickness was measured in 2146 adults in the Cardiovascular Risk in Young Finns Study. These subjects have blood pressure data available dating back to their childhood (baseline in 1980, ages 3 to 18 years). RESULTS:Baseline pulse pressure measured in adolescence was significantly related to carotid intima-media thickness measured in adulthood 21 years later (r=0.123, P<0.0001). The relation remained significant (P=0.0029) in models adjusted for age, sex, adolescent mean arterial pressure, adult systolic pressure, adult pulse pressure, body mass index, smoking, physical activity, and carotid artery diameter. Each 10 mm Hg increment in pulse pressure was associated with a 0.008-mm (95% CI, 0.003 to 0.013 mm) increase in carotid intima-media thickness. CONCLUSIONS:Exposure to wide pulse pressure in adolescence may induce changes that contribute to carotid artery intima-media thickening.

journal_name

Stroke

journal_title

Stroke

authors

Raitakari OT,Juonala M,Taittonen L,Jula A,Laitinen T,Kähönen M,Viikari JS

doi

10.1161/STROKEAHA.108.525253

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

1519-21

issue

4

eissn

0039-2499

issn

1524-4628

pii

STROKEAHA.108.525253

journal_volume

40

pub_type

杂志文章

相关文献

STROKE文献大全
  • Descriptive analysis of the Boston criteria applied to a Dutch-type cerebral amyloid angiopathy population.

    abstract:BACKGROUND AND PURPOSE:Validation of the Boston criteria for the in vivo diagnosis of cerebral amyloid angiopathy (CAA) is challenging, because noninvasive diagnostic tests do not exist. Hereditary cerebral hemorrhage with amyloidosis-Dutch type is an accepted monogenetic model of CAA and diagnosis can be made with cer...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/STROKEAHA.109.554378

    authors: van Rooden S,van der Grond J,van den Boom R,Haan J,Linn J,Greenberg SM,van Buchem MA

    更新日期:2009-09-01 00:00:00

  • Obesity Paradox in Intracerebral Hemorrhage.

    abstract::Background and Purpose- Although obesity is an established risk factor for cardiovascular disease and stroke, studies have shown evidence of an obesity paradox-a protective effect of obesity in patients who already have these disease states. Data on the obesity paradox in intracerebral hemorrhage is limited. Methods- ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.024638

    authors: Persaud SR,Lieber AC,Donath E,Stingone JA,Dangayach NS,Zhang X,Mocco J,Kellner CP

    更新日期:2019-04-01 00:00:00

  • Vertebrobasilar stenosis predicts high early recurrent stroke risk in posterior circulation stroke and TIA.

    abstract:BACKGROUND AND PURPOSE:20% of ischemic stroke is in the posterior circulation, but there is little prospective data on early recurrent stroke risk and whether vertebrobasilar stenosis predicts a high recurrence risk. This natural history data are important as it is technically possible to stent such lesions. Contrast e...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.553859

    authors: Gulli G,Khan S,Markus HS

    更新日期:2009-08-01 00:00:00

  • Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis.

    abstract:BACKGROUND AND PURPOSE:The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis. METHODS:We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Web of Science. Twenty-two studies comprisi...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析,评审

    doi:10.1161/STROKEAHA.113.002590

    authors: Gouya G,Arrich J,Wolzt M,Huber K,Verheugt FW,Gurbel PA,Pirker-Kees A,Siller-Matula JM

    更新日期:2014-02-01 00:00:00

  • Self-reported depression and use of antidepressants after stroke: a national survey.

    abstract:BACKGROUND AND PURPOSE:Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS:In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke sur...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000121643.86762.9a

    authors: Eriksson M,Asplund K,Glader EL,Norrving B,Stegmayr B,Terént A,Asberg KH,Wester PO,Riks-Stroke Collaboration.

    更新日期:2004-04-01 00:00:00

  • Cathecholamine and 5-hydroxytryptamine levels in ischemic brain. Influence of p-chlorophenylalanine.

    abstract::The effect of ischemia on catecholamine and 5-hydroxytryptamine (5-HT) levels in brain cortex was examined in the gerbil stroke model. Unilateral common carotid artery occlusion produced bilateral decrease in cortical dopamine levels in gerbils both symptomatic and asymptomatic of cerbral ischemia. The 5-HT progressiv...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.8.3.341

    authors: Welch KM,Chabi E,Buckingham J,Bergin B,Achar VS,Meyer JS

    更新日期:1977-05-01 00:00:00

  • Socioeconomic differences in quality of care and clinical outcome after stroke: a nationwide population-based study.

    abstract:BACKGROUND AND PURPOSE:The association among socioeconomic status, quality of care, and clinical outcome after stroke remains poorly understood. In a Danish nationwide follow-up study, we examined whether socioeconomic-related differences in acute stroke care occur and, if so, whether they explain socioeconomic differe...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.611871

    authors: Langagergaard V,Palnum KH,Mehnert F,Ingeman A,Krogh BR,Bartels P,Johnsen SP

    更新日期:2011-10-01 00:00:00

  • Diffusion and perfusion magnetic resonance imaging studies to evaluate a noncompetitive N-methyl-D-aspartate antagonist and reperfusion in experimental stroke in rats.

    abstract:BACKGROUND AND PURPOSE:Diffusion magnetic resonance imaging (MRI) can quantitatively detect focal ischemic injury within minutes of onset, and perfusion MRI can evaluate the brain's microcirculation. N-Methyl-D-aspartate (NMDA) antagonists and reperfusion can reduce lesion size in stroke models. We used diffusion and p...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.12.2074

    authors: Minematsu K,Fisher M,Li L,Sotak CH

    更新日期:1993-12-01 00:00:00

  • Embolic lesion pattern in stroke patients with patent foramen ovale compared with patients lacking an embolic source.

    abstract:BACKGROUND AND PURPOSE:Multiple acute ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI-MRI) are thought to be of embolic origin. However, in several patients with multiple ischemic lesions on DWI-MRI, no embolic source was detected, despite a thorough clinical work-up. Stroke etiology in such case...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000231645.22128.ab

    authors: Jauss M,Wessels T,Trittmacher S,Allendörfer J,Kaps M

    更新日期:2006-08-01 00:00:00

  • Effects of the novel thromboxane antagonist Bay U 3405 on experimental coronary artery disease.

    abstract::Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:

    authors: Fiedler VB,Seuter F,Perzborn E

    更新日期:1990-12-01 00:00:00

  • Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion.

    abstract:BACKGROUND AND PURPOSE:Changes in vascular permeability are well-known and important consequences of cerebral ischemia. The development of edema and of petechial hemorrhage is connected to altered vascular integrity. A major part in microvascular integrity is played by the basal lamina. METHODS:The fates of the basal ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.11.2120

    authors: Hamann GF,Okada Y,Fitridge R,del Zoppo GJ

    更新日期:1995-11-01 00:00:00

  • Sensory sequelae of medullary infarction: differences between lateral and medial medullary syndrome.

    abstract:BACKGROUND AND PURPOSE:A comparison between long-term sensory sequelae of lateral medullary infarction (LMI) and medial medullary infarction (MMI) has never been made. METHODS:We studied 55 patients with medullary infarction (41 with LMI and 14 with MMI) who were followed up for >6 months. We examined and interviewed ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.12.2697

    authors: Kim JS,Choi-Kwon S

    更新日期:1999-12-01 00:00:00

  • Effects of flunarizine on neurological recovery and spinal cord blood flow in experimental spinal cord ischemia in rabbits.

    abstract:BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.10.1547

    authors: Johnson SH,Kraimer JM,Graeber GM

    更新日期:1993-10-01 00:00:00

  • Mirror therapy for improving motor function after stroke.

    abstract:OBJECTIVES:This systematic review summarizes the effectiveness of mirror therapy for improving motor function, activities of daily living, pain, and visuospatial neglect in patients after stroke. METHODS:We searched the Cochrane Stroke Group’s Trials Register (June 2011), the Cochrane Central Register of Controlled Tr...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/strokeaha.112.673087

    authors: Thieme H,Mehrholz J,Pohl M,Behrens J,Dohle C

    更新日期:2013-01-01 00:00:00

  • Interobserver agreement of ASPECT score distribution for noncontrast CT, CT angiography, and CT perfusion in acute stroke.

    abstract:BACKGROUND AND PURPOSE:The Alberta Stroke program early CT score (ASPECTS) is a semiquantative scale for estimating extent and distribution of early ischemic changes within the MCA territory in the acute stroke setting. Good interobserver agreement of total ASPECTS is demonstrated for noncontrast CT (NCCT) and other im...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.665208

    authors: Finlayson O,John V,Yeung R,Dowlatshahi D,Howard P,Zhang L,Swartz R,Aviv RI

    更新日期:2013-01-01 00:00:00

  • Effect of PCO2 changes induced by head-upright tilt on transcranial Doppler recordings.

    abstract:BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data. MET...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.6.1195

    authors: Cencetti S,Bandinelli G,Lagi A

    更新日期:1997-06-01 00:00:00

  • Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke.

    abstract:BACKGROUND AND PURPOSE:5' adenosine monophosphate-dependent protein kinase (AMPK) acts as a metabolic sensor. AMPK is elevated under ischemic conditions, but the role of AMPK in ischemic brain remains controversial. In this study, we examined the effects of AMPK inhibition using both pharmacological and genetic approac...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.107.490904

    authors: Li J,Zeng Z,Viollet B,Ronnett GV,McCullough LD

    更新日期:2007-11-01 00:00:00

  • Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score ≤6.

    abstract:BACKGROUND AND PURPOSE:In acute ischemic stroke patients, diffusion-weighted imaging (DWI)-Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is correlated with infarct volume and is an independent factor of functional outcome. Patients with pretreatment DWI-ASPECTS ≤6 were excluded or under-represented i...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究

    doi:10.1161/STROKEAHA.116.015202

    authors: Desilles JP,Consoli A,Redjem H,Coskun O,Ciccio G,Smajda S,Labreuche J,Preda C,Ruiz Guerrero C,Decroix JP,Rodesch G,Mazighi M,Blanc R,Piotin M,Lapergue B,ETIS (Endovascular Treatment in Ischemic Stroke) Research Investigator

    更新日期:2017-04-01 00:00:00

  • Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis.

    abstract:BACKGROUND AND PURPOSE:Progression of asymptomatic carotid artery stenosis (ACAS) in patients with >50% luminal narrowing is considered a potential risk factor for ischemic stroke; however, subclinical molecular biomarkers of ACAS progression are lacking. Recent studies suggest a regulatory function for several microRN...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013650

    authors: Dolz S,Górriz D,Tembl JI,Sánchez D,Fortea G,Parkhutik V,Lago A

    更新日期:2017-01-01 00:00:00

  • Polymorphisms of coagulation factor XIII subunit A and risk of nonfatal hemorrhagic stroke in young white women.

    abstract:BACKGROUND AND PURPOSE:Although family studies have suggested a genetic influence on hemorrhagic stroke, the underlying genetic risk factors remain poorly defined. Coagulation factor XIII, which is involved in hemostasis, fibrinolysis, vascular remodeling, and tissue repair, represents a candidate gene for hemorrhagic ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/hs1101.098150

    authors: Reiner AP,Schwartz SM,Frank MB,Longstreth WT Jr,Hindorff LA,Teramura G,Rosendaal FR,Gaur LK,Psaty BM,Siscovick DS

    更新日期:2001-11-01 00:00:00

  • Gender differences in treatment of severe carotid stenosis after transient ischemic attack.

    abstract:BACKGROUND AND PURPOSE:Gender differences in carotid endarterectomy (CEA) rates after transient ischemic attack are not well studied, although some reports suggest that eligible men are more likely to have CEA than women after stroke. METHODS:We retrospectively identified all patients diagnosed with transient ischemic...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.580977

    authors: Poisson SN,Johnston SC,Sidney S,Klingman JG,Nguyen-Huynh MN

    更新日期:2010-09-01 00:00:00

  • Factors affecting the prognosis in thalamic hemorrhage.

    abstract::The present study deals with the factors affecting the prognosis in the acute stage of 29 cases with hypertensive thalamic hemorrhage diagnosed by CT scan. It was thought that the following factors were significantly related to the outcome of the patients who were unable to lead daily life, remained in vegetative stat...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.14.4.493

    authors: Kwak R,Kadoya S,Suzuki T

    更新日期:1983-07-01 00:00:00

  • Postischemic application of lipid peroxidation inhibitor U-101033E reduces neuronal damage after global cerebral ischemia in rats.

    abstract:BACKGROUND AND PURPOSE:The lipid peroxidation inhibitor U-101033E was examined for effects on cerebral blood flow (CBF), cortical tissue hemoglobin oxygen saturation (HbSo2), and neuronal damage. METHODS:Fifteen minutes of global cerebral ischemia was induced by two-vessel occlusion and hypobaric hypotension. Wistar r...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.6.1240

    authors: Soehle M,Heimann A,Kempski O

    更新日期:1998-06-01 00:00:00

  • Should decompressive surgery be performed in malignant cerebral venous thrombosis?: a series of 12 patients.

    abstract:BACKGROUND AND PURPOSE:In malignant cerebral venous thrombosis (CVT) patients, emergency decompressive surgery has been suggested as a life-saving procedure. We report 12 patients with malignant CVT, among whom 8 underwent operation. METHODS:Retrospective study of 12 patients from 3 stroke units who had a malignant CV...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.572909

    authors: Théaudin M,Crassard I,Bresson D,Saliou G,Favrole P,Vahedi K,Denier C,Bousser MG

    更新日期:2010-04-01 00:00:00

  • Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia.

    abstract:BACKGROUND AND PURPOSE:Most previous studies addressed the cognitive impact of lacunar infarcts using radiologic correlations that are known to correlate poorly with neuropathological data. Moreover, absence of systematic bilateral assessment of vascular lesions and masking effects of Alzheimer disease pathology and ma...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000166052.89772.b5

    authors: Gold G,Kövari E,Herrmann FR,Canuto A,Hof PR,Michel JP,Bouras C,Giannakopoulos P

    更新日期:2005-06-01 00:00:00

  • Cardiac cycle-dependent alternating flow in vertebral arteries with subclavian artery stenoses.

    abstract::Continuous-wave Doppler sonography is a reliable method for detecting severe subclavian stenosis and occlusion as well as subclavian steal. Intermediate stages leading to subclavian steal can also be detected. These are characterized by a cardiac-phase-dependent alternating flow direction in the vertebral artery. Some...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.9.3.229

    authors: von Reutern GM,Pourcelot L

    更新日期:1978-05-01 00:00:00

  • The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length.

    abstract:BACKGROUND AND PURPOSE:We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. METHODS:In 138 patients who presented with acute middle cerebral artery stroke an...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.609693

    authors: Riedel CH,Zimmermann P,Jensen-Kondering U,Stingele R,Deuschl G,Jansen O

    更新日期:2011-06-01 00:00:00

  • Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients.

    abstract:BACKGROUND AND PURPOSE:The ABCD system was developed to predict early stroke risk after transient ischemic attack. Incorporation of brain imaging findings has been suggested, but reports have used inconsistent methods and been underpowered. We therefore performed an international, multicenter collaborative study of the...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究

    doi:10.1161/STROKEAHA.110.578971

    authors: Giles MF,Albers GW,Amarenco P,Arsava MM,Asimos A,Ay H,Calvet D,Coutts S,Cucchiara BL,Demchuk AM,Johnston SC,Kelly PJ,Kim AS,Labreuche J,Lavallee PC,Mas JL,Merwick A,Olivot JM,Purroy F,Rosamond WD,Sciolla R,Rothw

    更新日期:2010-09-01 00:00:00

  • Age of collagen in intracranial saccular aneurysms.

    abstract:BACKGROUND AND PURPOSE:The chronological development and natural history of cerebral aneurysms (CAs) remain incompletely understood. We used (14)C birth dating of a main constituent of CAs, that is, collagen type I, as an indicator for biosynthesis and turnover of collagen in CAs in relation to human cerebral arteries ...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/STROKEAHA.114.005461

    authors: Etminan N,Dreier R,Buchholz BA,Beseoglu K,Bruckner P,Matzenauer C,Torner JC,Brown RD Jr,Steiger HJ,Hänggi D,Macdonald RL

    更新日期:2014-06-01 00:00:00

  • Transcranial color-coded sonography of the basal cerebral circulation. Reference data from 115 volunteers.

    abstract:BACKGROUND AND PURPOSE:Transcranial color-coded sonography is a new development in noninvasive cerebral vascular imaging. Reference data using this technique are described. METHODS:Blood velocities and pulsatility and resistance indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, ver...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.2.390

    authors: Martin PJ,Evans DH,Naylor AR

    更新日期:1994-02-01 00:00:00