Interobserver agreement of ASPECT score distribution for noncontrast CT, CT angiography, and CT perfusion in acute stroke.

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events. METHODS:Two hundred three community-dwelling adults (Northern Manhattan Study; age, 68 ± 11; age range, 50 to 93 ...

journal_title：Stroke

authors： Carrelli AL,Walker MD,Lowe H,McMahon DJ,Rundek T,Sacco RL,Silverberg SJ

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) and carotid duplex (CD) provide rapid and safe screening for stroke patients but are highly operator dependent. We explored the feasibility of telemedicine (TM)-guided TCD/CD administered by a health care provider inexperienced with ultrasound. METHODS:Dual video scree...

journal_title：Stroke

authors： Mikulik R,Alexandrov AV,Ribo M,Garami Z,Porche NA,Fulep E,Grotta JC,Wojner-Alexandrov AW,Choi JY

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been proposed that spin trap agents such as N:-t-butyl-phenylnitrone (PBN) may be useful as neuroprotective agents in the treatment of ischemia and stroke. However, to date, there is little information concerning the effectiveness of spin trap agents when administered in combination with t...

journal_title：Stroke

authors： Lapchak PA,Chapman DF,Zivin JA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported on the correlation of ultrasonic carotid plaque morphology, cerebrovascular symptoms, and intraplaque hemorrhage. This study correlates ultrasonic carotid plaque morphology with the degree of carotid stenosis. METHODS:Carotid arteries (n=2460) were examined by using...

journal_title：Stroke

authors： AbuRahma AF,Wulu JT Jr,Crotty B

更新日期：2002-07-01 00:00:00

abstract：:To clarify the nature of ischemic striatal dopamine release during the earliest periods of neuronal injury, we used chronoamperometry to measure dopamine levels every 60 seconds during various durations of ischemia in 32 gerbils. Catecholamine-selective electrodes were implanted into the brains of anesthetized gerbils...

journal_title：Stroke

authors： Ahn SS,Blaha CD,Alkire MT,Wood E,Gray-Allan P,Marrocco RT,Moore WS

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aims of this study were to determine the magnitude of the increase in fracture risk after hospitalization for stroke, and in particular to determine the time course of this risk. METHODS:The records of the Swedish register of patients admitted during 1987-1996 were examined to identify all p...

journal_title：Stroke

authors： Kanis J,Oden A,Johnell O

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. The roles that reproductive steroi...

journal_title：Stroke

authors： Shearman AM,Cooper JA,Kotwinski PJ,Humphries SE,Mendelsohn ME,Housman DE,Miller GJ

更新日期：2005-10-01 00:00:00

abstract：:Background and Purpose- Hyperglycemia is a negative prognostic factor after acute ischemic stroke but is not known whether glucose is associated with the effects of endovascular thrombectomy (EVT) in patients with large-vessel stroke. In a pooled-data meta-analysis, we analyzed whether serum glucose is a treatment mod...

journal_title：Stroke

authors： Chamorro Á,Brown S,Amaro S,Hill MD,Muir KW,Dippel DWJ,van Zwam W,Butcher K,Ford GA,den Hertog HM,Mitchell PJ,Demchuk AM,Majoie CBLM,Bracard S,Sibon I,Jadhav AP,Lara-Rodriguez B,van der Lugt A,Osei E,Renú A,Richard

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study seeks to define a specific gene whose mutation leads to disease. METHODS:More than 500 IA probands and 100 affected families were enrolled and clinically characterized. Whole exome sequencing was ...

journal_title：Stroke

authors： Santiago-Sim T,Fang X,Hennessy ML,Nalbach SV,DePalma SR,Lee MS,Greenway SC,McDonough B,Hergenroeder GW,Patek KJ,Colosimo SM,Qualmann KJ,Hagan JP,Milewicz DM,MacRae CA,Dymecki SM,Seidman CE,Seidman JG,Kim DH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The proteoglycan versican is an excellent candidate gene for intracranial aneurysms (IAs) because it plays an important role in extracellular matrix assembly and is localized in a previously implicated locus for IAs on chromosome 5q. METHODS:We analyzed all the common variations using 16-tag sin...

journal_title：Stroke

authors： Ruigrok YM,Rinkel GJ,Wijmenga C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The watershed cortical areas are the first to be deprived of sufficient blood flow in the event of cerebral hypoperfusion and will be the sites of watershed microinfarcts. Cerebral hypoperfusion is associated with Alzheimer disease (AD), but information regarding the occurrence of watershed corti...

journal_title：Stroke

authors： Suter OC,Sunthorn T,Kraftsik R,Straubel J,Darekar P,Khalili K,Miklossy J

更新日期：2002-08-01 00:00:00

abstract：:Unilateral stimulation of the cervical sympathetic in dogs had no effect on cerebral blood flow (CBF) measured by the venous outflow technique. Since this technique measured CBF from both cerebral hemispheres, small changes induced by unilateral stimulation could have been masked by a large constant CBF measured from ...

journal_title：Stroke

authors： Barber BJ,Martin JS,Rapela CE

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

journal_title：Stroke

authors： Rothwell PM,Slattery J,Warlow CP

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Depression after stroke is common. Like stroke, transient ischemic attack (TIA) is a manifestation of long-term atherosclerotic damage to the brain. However, the risk of depression developing after a TIA is uncertain. We studied whether TIA increases the risk of incident late-life depression. ME...

journal_title：Stroke

authors： Luijendijk HJ,Stricker BH,Wieberdink RG,Koudstaal PJ,Hofman A,Breteler MM,Tiemeier H

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Systemic inflammatory response syndrome (SIRS) is a generalized inflammatory state. The primary goal of the study was to determine whether differences exist in outcomes in SIRS and non-SIRS intravenous tissue-type plasminogen activator-treated patients. METHODS:Consecutive patients were retrospe...

journal_title：Stroke

authors： Boehme AK,Kapoor N,Albright KC,Lyerly MJ,Rawal PV,Bavarsad Shahripour R,Alvi M,Houston JT,Sisson A,Beasley TM,Alexandrov AW,Alexandrov AV,Miller DW

更新日期：2013-08-01 00:00:00

abstract：:Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize...

journal_title：Stroke

authors： Bornstein NM,Saver JL,Diener HC,Gorelick PB,Shuaib A,Solberg Y,Devlin T,Leung T,Molina CA,ImpACT-24A Investigators † .,ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators lis

更新日期：2019-05-23 00:00:00

abstract：:During the 5-year period from 1980 to 1984, the incidence of subarachnoid hemorrhage due only to rupture of aneurysms was investigated in Izumo City, a small city with a population of 79,026. Additionally, to ascertain the relation of incidence to the size of the geographic area and/or population, a similar analysis w...

journal_title：Stroke

authors： Inagawa T,Ishikawa S,Aoki H,Takahashi M,Yoshimoto H

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Improved neurological outcome with postarrest hypertensive hemodilution in an earlier study could be the result of more homogeneous cerebral perfusion and improved O2 delivery. We explored global, regional, and local cerebral blood flow by stable xenon-enhanced computed tomography and global cerebral metabol...

journal_title：Stroke

authors： Leonov Y,Sterz F,Safar P,Johnson DW,Tisherman SA,Oku K

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the reproducibility, interobserver variability, and application to clinical studies of a new method for the quantitative assessment of carotid plaque echogenicity. METHODS:Carotid plaques were scanned with the use of ultrasound, and their images were stored in a computer. The...

journal_title：Stroke

authors： Sabetai MM,Tegos TJ,Nicolaides AN,Dhanjil S,Pare GJ,Stevens JM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Occluding a large intracranial artery in rats produces a brain lesion that grows in terms of an increase in both surface area and number of necrotic neurons. The present study investigated whether reperfusing the ischemic territory 30 to 60 minutes after the arterial occlusion would have a benefi...

journal_title：Stroke

authors： Garcia JH,Wagner S,Liu KF,Hu XJ

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Visit-to-visit and day-to-day variability in systolic blood pressure (SBP) are associated with an increased risk of stroke, more strongly than variability on 24-hour ambulatory BP monitoring, but underlying physiological mechanisms are unclear. We related potentially relevant physiological charac...

journal_title：Stroke

authors： Webb AJ,Rothwell PM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial atherosclerosis is one of the main causes of stroke, and high-resolution magnetic resonance imaging provides useful imaging biomarkers related to the risk of ischemic events. This study aims to evaluate differences in histogram features between culprit and nonculprit intracranial ath...

journal_title：Stroke

authors： Shi Z,Li J,Zhao M,Peng W,Meddings Z,Jiang T,Liu Q,Teng Z,Lu J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some studies have suggested a link between impaired cerebral hemodynamics and stroke in patients with carotid stenosis. The aim of this study was to assess the effects of severe carotid stenosis on cerebrovascular reactivity and the possible changes after endarterectomy. METHODS:Using bilateral ...

journal_title：Stroke

authors： Silvestrini M,Troisi E,Matteis M,Cupini LM,Caltagirone C

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains unknown whether the effects of 0.6 mg/kg alteplase differ with occlusion site of the middle cerebral artery (MCA). We therefore evaluated the effects of 0.6 mg/kg intravenous alteplase in patients with different sites of MCA occlusion. METHODS:An exploratory analysis was made of 57 pa...

journal_title：Stroke

authors： Hirano T,Sasaki M,Mori E,Minematsu K,Nakagawara J,Yamaguchi T,Japan Alteplase Clinical Trial II Group.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke. Recent evidence suggests that uric acid may be an important causal agent in cardiovascular disease, for example, by inducing renal disease and hence h...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Witteman JC,Breteler MM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS:Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or...

journal_title：Stroke

authors： Gaberel T,Gakuba C,Hebert M,Montagne A,Agin V,Rubio M,Emery E,Vivien D,Gauberti M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to cl...

journal_title：Stroke

authors： Saini M,Ikram K,Hilal S,Qiu A,Venketasubramanian N,Chen C

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The trends in stroke incidence reported so far have not been entirely consistent, although declining trends in mortality from stroke have been reported from a number of studies around the world. This study aims to evaluate the 10-year trends (from 1983 through 1992) in incidence, attack rate, and...

journal_title：Stroke

authors： Tuomilehto J,Rastenyte D,Sivenius J,Sarti C,Immonen-Räihä P,Kaarsalo E,Kuulasmaa K,Narva EV,Salomaa V,Salmi K,Torppa J

更新日期：1996-05-01 00:00:00

abstract：:Background and Purpose- Prehospital routing algorithms for patients with suspected stroke because of large vessel occlusions should account for likelihood of benefit from endovascular therapy (EVT), risk of alteplase delays, and transport times. We built a mathematical model to give a real-time, location-based optimal...

journal_title：Stroke

authors： Ali A,Zachrison KS,Eschenfeldt PC,Schwamm LH,Hur C

更新日期：2018-10-01 00:00:00