Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation.

abstract：BACKGROUND AND PURPOSE:To study the longitudinal relationship of functional change in walking ability and change in time-dependent covariates and to develop a multivariate regression model to predict longitudinal change of walking ability. METHODS:A total of 101 acute stroke patients with first-ever ischemic middle ce...

journal_title：Stroke

authors： Kollen B,van de Port I,Lindeman E,Twisk J,Kwakkel G

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Policy makers require evidence on the costs and outcomes of different ways of organizing stroke care. This study compared the costs and survival of different ways of providing stroke care. METHODS:Hospitalized stroke patients from 13 European centers were included, with demographic, case-mix, an...

journal_title：Stroke

authors： Grieve R,Hutton J,Bhalla A,Rastenytë D,Ryglewicz D,Sarti C,Lamassa M,Giroud M,Dundas R,Wolfe CD

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Robust measures of functional outcome are required to determine treatment effects in stroke trials. Of the various measures available, the Barthel index (BI) is one of the more prevalent. We aimed to describe validity, reliability, and responsiveness (clinimetric properties) of the BI in stroke t...

journal_title：Stroke

authors： Quinn TJ,Langhorne P,Stott DJ

更新日期：2011-04-01 00:00:00

abstract：:Background and Purpose- Given inconclusive studies, it is debated whether clinical and imaging characteristics, as well as functional outcome, differ among patients with intracerebral hemorrhage (ICH) related to vitamin K antagonists (VKA) versus non-vitamin K antagonist (NOAC)-related ICH. Notably, clinical character...

journal_title：Stroke

authors： Gerner ST,Kuramatsu JB,Sembill JA,Sprügel MI,Hagen M,Knappe RU,Endres M,Haeusler KG,Sobesky J,Schurig J,Zweynert S,Bauer M,Vajkoczy P,Ringleb PA,Purrucker JC,Rizos T,Volkmann J,Müllges W,Kraft P,Schubert AL,Erbgut

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Statin use may be associated with improved outcome in intracerebral hemorrhage patients. However, the topic remains controversial. Our analysis examined the effect of prior, continued, or new statin use on intracerebral hemorrhage outcomes using the ERICH (Ethnic/Racial Variations of Intracerebra...

journal_title：Stroke

authors： Siddiqui FM,Langefeld CD,Moomaw CJ,Comeau ME,Sekar P,Rosand J,Kidwell CS,Martini S,Osborne JL,Stutzman S,Hall C,Woo D

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown. METHODS:we genotyped single nucleotide polymorphisms (...

journal_title：Stroke

authors： Ronald J,Rajagopalan R,Cerrato F,Nord AS,Hatsukami T,Kohler T,Marcovina S,Heagerty P,Jarvik GP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple studies have shown that negative computed tomographic angiograms (CTAs) are reliable in excluding aneurysms in patients with isolated perimesencephalic subarachnoid hemorrhage (pSAH). We evaluate the use of digital subtraction angiography versus CTA for initial diagnosis and of angiograp...

journal_title：Stroke

authors： Kalra VB,Wu X,Matouk CC,Malhotra A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parental stroke has been related to an increased risk of stroke in the offspring. This study examines whether parental stroke is also associated with increased vascular brain injury and poorer cognitive performance among offspring free of clinical stroke. METHODS:Multivariable regression analyse...

journal_title：Stroke

authors： Weinstein G,Beiser AS,Au R,Decarli C,Wolf PA,Seshadri S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from epidemiological and case-control studies suggest that increased total homocysteine (tHcy) levels are associated with increased risk for thromboembolic disease. The mechanisms by which hyperhomocysteinemia contributes to thrombogenesis are incompletely understood. The main objectives of ...

journal_title：Stroke

authors： Kristensen B,Malm J,Nilsson TK,Hultdin J,Carlberg B,Dahlén G,Olsson T

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The limited walking ability that follows a stroke restricts the patient's independent mobility about the home and community, a significant social handicap. To improve the in-hospital prediction of functional outcome, the relationships between impairment, disability, and handicap were assessed wit...

journal_title：Stroke

authors： Perry J,Garrett M,Gronley JK,Mulroy SJ

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The risk of major vascular events after an initial episode of cerebral ischemia in patients with nonrheumatic atrial fibrillation (NRAF) varies from 2% to 15% in the first year and is approximately 5% yearly thereafter. Few studies have reported on risk factors that can be used to identify high-r...

journal_title：Stroke

authors： van Latum JC,Koudstaal PJ,Venables GS,van Gijn J,Kappelle LJ,Algra A

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rarity of intracranial vascular malformations (IVMs) and the infrequency of their outcomes make large, prolonged cohort studies the best means to evaluate their frequency and prognosis. METHODS:The Scottish Intracranial Vascular Malformation Study (SIVMS) is a prototype prospective, populati...

journal_title：Stroke

authors： Al-Shahi R,Bhattacharya JJ,Currie DG,Papanastassiou V,Ritchie V,Roberts RC,Sellar RJ,Warlow CP,Scottish Intracranial Vascular Malformation Study Collaborators.

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS:Adult male wild-type or PAR-1 knock...

journal_title：Stroke

authors： Wang J,Jin H,Hua Y,Keep RF,Xi G

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the second leading cause of death in Japan. We sought to examine changes in stroke mortality rates by age, sex, and birth cohorts from 1950 to 1997. METHODS:The numbers of deaths from stroke and the population by age and sex in subjects aged 55 to 79 years between 1950 and 1997 were ob...

journal_title：Stroke

authors： Liu L,Ikeda K,Yamori Y

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Monocytes may contribute to secondary injury after intracerebral hemorrhage (ICH). We tested the association of absolute monocyte count with 30-day ICH case fatality in a multiethnic cohort. METHODS:Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a prospective, multicenter,...

journal_title：Stroke

authors： Walsh KB,Sekar P,Langefeld CD,Moomaw CJ,Elkind MS,Boehme AK,James ML,Osborne J,Sheth KN,Woo D,Adeoye O

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of peripheral arteries in hypercholesterolemic animals suggest that increased generation of superoxide contributes to endothelial dysfunction, especially in the presence of atherosclerotic lesions. We tested the hypothesis that vasomotor function is impaired in cerebral arterioles during ...

journal_title：Stroke

authors： Kitayama J,Faraci FM,Lentz SR,Heistad DD

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess outcomes after endovascular treatment/therapy of acute ischemic stroke, overall and by subgroups, and looked for predictors of outcome. METHODS:We used data from a mandatory, population-based registry that includes external monitoring of completeness, which assesses reperfusi...

journal_title：Stroke

authors： Abilleira S,Cardona P,Ribó M,Millán M,Obach V,Roquer J,Cánovas D,Martí-Fàbregas J,Rubio F,Alvarez-Sabín J,Dávalos A,Chamorro A,de Miquel MA,Tomasello A,Castaño C,Macho JM,Ribera A,Gallofré M,Catalan Stroke Code and Re

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the study is to compare the reliability of the Barthel activities of daily living score, which assesses disability, with the Rankin scale, which assesses handicap, and to determine their mutual agreement. METHODS:Fifty patients with stroke of varying severity were identified by a ...

journal_title：Stroke

authors： Wolfe CD,Taub NA,Woodrow EJ,Burney PG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess the long-term predictive usefulness of bone mineral density (BMD) for stroke incidence and stroke mortality. METHODS:The First National Health and Nutrition Examination Survey data were obtained from a nationally representative sample of noninstitutionalized civilians. A coho...

journal_title：Stroke

authors： Mussolino ME,Madans JH,Gillum RF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chlamydia pneumoniae infection has recently become noteworthy in relation to atherosclerosis. We investigated by immunohistochemistry the distribution of C pneumoniae infection in the atherosclerotic carotid artery. METHODS:Twenty carotid atherosclerotic lesions that were resected during carotid...

journal_title：Stroke

authors： Yamashita K,Ouchi K,Shirai M,Gondo T,Nakazawa T,Ito H

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

journal_title：Stroke

authors： Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

更新日期：2006-02-01 00:00:00

abstract：:Nontraumatic intracerebral hemorrhage (ICH) remains a devastating condition with 30-day mortality rates of 35% to 52%. Until the pathophysiology of this condition is better understood, it will not be possible to develop effective therapies. Studies of cerebral blood flow and metabolism in patients with acute ICH show ...

journal_title：Stroke

authors： Powers WJ

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A significant number of patients with aneurysmal subarachnoid hemorrhage are active smokers and at risk for acute nicotine withdrawal. There is conflicting literature regarding the vascular effects of nicotine and theoretical concern that it may worsen vasospasm. The literature on the safety of n...

journal_title：Stroke

authors： Carandang RA,Barton B,Rordorf GA,Ogilvy CS,Sims JR

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify the most powerful binary measures of the treatment effect of tissue plasminogen activator (tPA) in the National Institute of Neurological Disorders and Stroke (NINDS) rTPA Stroke Trial. METHODS:Using the Classification and Regression Tree (CART) algorithm, we evaluated bina...

journal_title：Stroke

authors： Broderick JP,Lu M,Kothari R,Levine SR,Lyden PD,Haley EC,Brott TG,Grotta J,Tilley BC,Marler JR,Frankel M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A locus containing the elastin gene has been linked to familial intracranial aneurysms in 2 distinct populations. We investigated the association of single-nucleotide polymorphisms (SNPs) and haplotypes of SNPs in the elastin gene with the occurrence of subarachnoid hemorrhage (SAH) from sporadic...

journal_title：Stroke

authors： Ruigrok YM,Seitz U,Wolterink S,Rinkel GJ,Wijmenga C,Urbán Z

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Improvements in cardiac surgery mortality and morbidity have focused interest on the neurological injury such as stroke and cognitive decline that may accompany an otherwise successful operation. We aimed to investigate (1) the rate of stroke, new ischemic change on MRI, and cognitive impairment ...

journal_title：Stroke

authors： Barber PA,Hach S,Tippett LJ,Ross L,Merry AF,Milsom P

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of lifestyle factors on the risk of ischemic stroke. METHODS:We used a nested case-control design. The cases comprised 163 persons (median age 69 years) admitted to a stroke unit and diagnosed with acute cerebral infarction. All cases had earlier participated in the North...

journal_title：Stroke

authors： Ellekjaer EF,Wyller TB,Sverre JM,Holmen J

更新日期：1992-06-01 00:00:00

abstract：:The media cross-sectional area, the media thickness, the internal radius and the ratio between media thickness and internal radius were determined in consecutive sections of extraparenchymal cerebral arteries of 7- and 12-month-old normotensive and spontaneously hypertensive rats. The study included intracranial pial ...

journal_title：Stroke

authors： Nordborg C,Fredriksson K,Johansson BB

更新日期：1985-03-01 00:00:00