Cerebral vascular dysfunction during hypercholesterolemia.

abstract：BACKGROUND AND PURPOSE:Chlamydia pneumoniae infection has recently become noteworthy in relation to atherosclerosis. We investigated by immunohistochemistry the distribution of C pneumoniae infection in the atherosclerotic carotid artery. METHODS:Twenty carotid atherosclerotic lesions that were resected during carotid...

journal_title：Stroke

authors： Yamashita K,Ouchi K,Shirai M,Gondo T,Nakazawa T,Ito H

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The newly-described computed tomography angiography (CTA) Spot Sign is present in about one third of patients with acute primary intracerebral hemorrhage (PICH) and predicts hematoma expansion. This sign has not been systematically evaluated in patients with secondary causes of ICH, and mimics ha...

journal_title：Stroke

authors： Gazzola S,Aviv RI,Gladstone DJ,Mallia G,Li V,Fox AJ,Symons SP

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prominent posterior cerebral artery (PCA) laterality upon 3-dimensional time-of-flight magnetic resonance angiography is often encountered in patients with middle cerebral artery occlusion. We hypothesized that this sign is correlated with improved functional outcome in patients with middle cereb...

journal_title：Stroke

authors： Ichijo M,Miki K,Ishibashi S,Tomita M,Kamata T,Fujigasaki H,Mizusawa H

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exogenously administered fructose-1,6-bisphosphate reduces neuronal injury from hypoxic or ischemic brain insults. To test the hypothesis that fructose-1,6-bisphosphate prevents changes in intracellular calcium ([Ca2+]i) and high-energy phosphate levels, we measured [Ca2+]i, intracellular pH (pHi...

journal_title：Stroke

authors： Bickler PE,Kelleher JA

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same tre...

journal_title：Stroke

authors： Kozak A,Ergul A,El-Remessy AB,Johnson MH,Machado LS,Elewa HF,Abdelsaid M,Wiley DC,Fagan SC

更新日期：2009-05-01 00:00:00

abstract：:Cerebral autoregulation can be duplicated in vitro using the large middle cerebral arteries from a calf. The limits of autoregulation were between 50 and 150 mm Hg. Excessively high pressures may lead to the appearance of the "sausage- or bead-string" response followed by forced dilation. These results suggest the exi...

journal_title：Stroke

authors： Vinall PE,Simeone FA

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Limited systemic fibrinolysis and reduced dosage are features of intra-arterial thrombolyis (IAT) that may be advantageous in the treatment of postoperative strokes. However, IAT may increase the risk of surgical bleeding. We sought to determine the safety of postoperative IAT. METHODS:This was ...

journal_title：Stroke

authors： Chalela JA,Katzan I,Liebeskind DS,Rasmussen P,Zaidat O,Suarez JI,Chiu D,Klucznick RP,Jauch E,Cucchiara BL,Saver J,Kasner SE

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study was performed to determine the relation between distribution of atherosclerosis and risk factors in Japanese patients with atherothrombotic occlusion. METHODS:We studied 154 patients with atherothrombotic occlusion of the extracranial internal carotid artery (n = 75, ICA group)...

journal_title：Stroke

authors： Yasaka M,Yamaguchi T,Shichiri M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular disease can complicate head and neck radiotherapy and result in transient ischemic attack and ischemic stroke. Although the incidence of radiation vasculopathy is predicted to rise with improvements in median cancer survival, the pathogenesis, natural history, and management of th...

journal_title：Stroke

authors： Plummer C,Henderson RD,O'Sullivan JD,Read SJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from prospective studies on the associations between B vitamin plasma levels and the risk of stroke are limited. We investigated the individual and combined effects of plasma folate, vitamin B12, and pyridoxal 5-phosphate (PLP) levels on the risk of ischemic stroke and transient ischemic att...

journal_title：Stroke

authors： Weikert C,Dierkes J,Hoffmann K,Berger K,Drogan D,Klipstein-Grobusch K,Spranger J,Möhlig M,Luley C,Boeing H

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is a common stroke symptom and leads to serious complications such as aspiration and pneumonia. Early dysphagia screening can reduce these complications. In many hospitals, dysphagia screening is performed by speech-language therapists who are often not available on weekends/holidays, w...

journal_title：Stroke

authors： Palli C,Fandler S,Doppelhofer K,Niederkorn K,Enzinger C,Vetta C,Trampusch E,Schmidt R,Fazekas F,Gattringer T

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hemodynamic properties of brain arteriovenous malformations (AVMs) with risk factors for a future hemorrhage are essentially unknown. We hypothesized that AVMs with anatomic properties, which are associated with an increased rupture risk, exhibit different hemodynamic characteristics than those w...

journal_title：Stroke

authors： Illies T,Forkert ND,Saering D,Wenzel K,Ries T,Regelsberger J,Wegscheider K,Fiehler J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a previous study, we occasionally found that the rat given naloxone in the preoptic region develops behavioral seizures. In view of knowledge that the forebrain including the medial septal nucleus provides cholinergic projections to the hippocampal formation, the present study examined the eff...

journal_title：Stroke

authors： Nishimura J,Endo Y,Kimura F

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Hyperpolarization of vascular muscle in response to activation of potassium channels is a major mechanism of vasodilatation. In cerebral blood vessels, four different potassium channels have been described: ATP-sensitive potassium channels, calcium-activated potassium channels, delayed rectifier potassium ch...

journal_title：Stroke

authors： Kitazono T,Faraci FM,Taguchi H,Heistad DD

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clear elucidation of the exact pathophysiological mechanisms of motor weakness in patients with subarachnoid hemorrhage has not yet been achieved. We attempted to investigate injury to the corticospinal tract in patients with subarachnoid hemorrhage using diffusion tensor imaging. METHODS:Twenty...

journal_title：Stroke

authors： Yeo SS,Choi BY,Chang CH,Kim SH,Jung YJ,Jang SH

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proinflammatory cytokines including interleukin-6 (IL-6) are supposed to play a pivotal role in the development of atherosclerosis. A common polymorphism in the promoter of the IL-6 gene (IL-6 -174G>C) affects plasma IL-6 concentrations and has been suggested as a risk factor for cardiovascular d...

journal_title：Stroke

authors： Weger M,Steinbrugger I,Haas A,März W,El-Shabrawi Y,Weger W,Schmut O,Renner W

更新日期：2005-02-01 00:00:00

abstract：:To determine the incidence of perioperative silent cerebral infarction, 97 patients who underwent carotid endarterectomy were prospectively studied with preoperative and postoperative computed tomograms. Thirty-one of 96 patients (32%) had findings of cerebral infarction on preoperative computed tomograms. Silent cere...

journal_title：Stroke

authors： Sise MJ,Sedwitz MM,Rowley WR,Shackford SR

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cavernous malformations of the brain (CMs) cause intracranial hemorrhage, but its reported frequency varies, partly attributable to study design. To improve the validity of future research, we aimed to develop a robust definition of CM hemorrhage. METHODS:We systematically reviewed the published...

journal_title：Stroke

authors： Al-Shahi Salman R,Berg MJ,Morrison L,Awad IA,Angioma Alliance Scientific Advisory Board.

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institute of Neurological Disorders and Stroke-Canadian Stroke Network Vascular Cognitive Impairment Harmonization working group proposed a brief cognitive protocol for screening of vascular cognitive impairment. We investigated the validity, reliability, and feasibility of the Montr...

journal_title：Stroke

authors： Wong A,Nyenhuis D,Black SE,Law LS,Lo ES,Kwan PW,Au L,Chan AY,Wong LK,Nasreddine Z,Mok V

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of thrombolysis in acute minor ischemic stroke (MIS) remains controversial. We sought to determine the safety and efficacy of intravenous tissue-type plasminogen activator (IV-tPA) in acute MIS patients with demonstrable penumbra on computed tomographic perfusion study. METHODS:Consecuti...

journal_title：Stroke

authors： Ng FC,Coote S,Frost T,Bladin C,Choi PM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery stenosis causes up to 10% of all ischemic strokes. Carotid endarterectomy (CEA) was introduced as a treatment to prevent stroke in the early 1950s. Carotid stenting (CAS) was introduced as a treatment to prevent stroke in 1994. METHODS:The Carotid Revascularization Endarterectomy ...

journal_title：Stroke

authors： Mantese VA,Timaran CH,Chiu D,Begg RJ,Brott TG,CREST Investigators.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The contribution of genetics to stroke risk, and whether this differs for different stroke subtypes, remainsuncertain. Genomewide complex trait analysis allows heritability to be assessed from genomewide association study (GWAS) data. Previous candidate gene studies have identified many associati...

journal_title：Stroke

authors： Bevan S,Traylor M,Adib-Samii P,Malik R,Paul NL,Jackson C,Farrall M,Rothwell PM,Sudlow C,Dichgans M,Markus HS

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS:In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke sur...

journal_title：Stroke

authors： Eriksson M,Asplund K,Glader EL,Norrving B,Stegmayr B,Terént A,Asberg KH,Wester PO,Riks-Stroke Collaboration.

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although family studies have suggested a genetic influence on hemorrhagic stroke, the underlying genetic risk factors remain poorly defined. Coagulation factor XIII, which is involved in hemostasis, fibrinolysis, vascular remodeling, and tissue repair, represents a candidate gene for hemorrhagic ...

journal_title：Stroke

authors： Reiner AP,Schwartz SM,Frank MB,Longstreth WT Jr,Hindorff LA,Teramura G,Rosendaal FR,Gaur LK,Psaty BM,Siscovick DS

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exposure to vascular risk factors has a gradual deleterious effect on brain MRI and cognitive measures. We explored whether a pattern of these measures exists that predicts stroke and Alzheimer disease (AD) risk. METHODS:A cognitive battery was administered to 1679 dementia and stroke-free Frami...

journal_title：Stroke

authors： Weinstein G,Beiser AS,Decarli C,Au R,Wolf PA,Seshadri S

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In children having suffered from neonatal arterial ischemic stroke, the relationship between contralesional hand performance and structural changes in brain areas remote from the infarct site was examined. METHODS:Using voxel-based morphometry, we correlated contralesional gross manual dexterity...

journal_title：Stroke

authors： Dinomais M,Hertz-Pannier L,Groeschel S,Delion M,Husson B,Kossorotoff M,Renaud C,Chabrier S,The Tich SN,AVCnn Study Group.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microanatomy studies reveal that most penetrating branches of middle cerebral artery (MCA) arise from the dorsal-superior surface of the trunk. Using high-resolution MRI, we sought to explore the plaque distribution of MCA atherosclerosis and its clinical relevance in relation to the orifices of ...

journal_title：Stroke

authors： Xu WH,Li ML,Gao S,Ni J,Zhou LX,Yao M,Peng B,Feng F,Jin ZY,Cui LY

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The estimated prevalence of intracranial atherosclerotic disease (IAD) in patients with stenosis of the extracranial internal carotid artery (ICA) varies between 20% and 50%. The benefits of carotid endarterectomy (CE) in patients with both IAD and symptomatic extracranial ICA stenosis are uncert...

journal_title：Stroke

authors： Kappelle LJ,Eliasziw M,Fox AJ,Sharpe BL,Barnett HJ

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...

journal_title：Stroke

authors： Patti J,Helenius J,Puri AS,Henninger N

更新日期：2016-10-01 00:00:00

abstract：:Cerebral blood flow (CBF) was determined in the rat under 70% nitrous oxide anesthesia and pentobarbital anesthesia. The application of the Fick principle technique of Kety et al. was modified utilizing 133Xe infused intravenously steadily for 30 seconds, at which time the animal was decapitated and the head frozen in...

journal_title：Stroke

authors： Matsumoto A,Namon R,Utsunomiya Y,Kogure K,Scheinberg P,Reinmuth OM

更新日期：1975-11-01 00:00:00