Association of polymorphisms and haplotypes in the elastin gene in Dutch patients with sporadic aneurysmal subarachnoid hemorrhage.

abstract：BACKGROUND AND PURPOSE:Prompt recognition of stroke symptoms is critical to timely treatment and women have increased delay to treatment. Women may be more likely to present with atypical symptoms, but this hypothesis has not been extensively evaluated. METHODS:We examined gender differences in the prevalence of prese...

journal_title：Stroke

authors： Stuart-Shor EM,Wellenius GA,DelloIacono DM,Mittleman MA

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We assessed whether the load of cerebral small vessel disease (cSVD) and its individual markers, including lacunes, white matter hyperintensities, microbleeds, and enlarged perivascular spaces (EPVS), are associated with arterial stiffness. METHODS:We evaluated cSVD markers in a cohort of 782 hy...

journal_title：Stroke

authors： Riba-Llena I,Jiménez-Balado J,Castañé X,Girona A,López-Rueda A,Mundet X,Jarca CI,Álvarez-Sabin J,Montaner J,Delgado P

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina. METHODS:We prospectively i...

journal_title：Stroke

authors： Bahit MC,Coppola ML,Riccio PM,Cipriano LE,Roth GA,Lopes RD,Feigin VL,Borrego Guerrero B,De Martino M,Díaz A,Ferrante D,Funaro F,Lavados P,Lewin ML,López DH,Macarrone P,Marciello R,Marino D,Martens C,Martínez P,Odr

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To define desirable target low-density lipoprotein (LDL) cholesterol levels for the prevention of stroke recurrence, a post hoc analysis was performed in the J-STARS study (Japan Statin Treatment Against Recurrent Stroke). METHODS:Subjects (n=1578) were divided into groups based on mean value of...

journal_title：Stroke

authors： Hosomi N,Kitagawa K,Nagai Y,Nakagawa Y,Aoki S,Nezu T,Kagimura T,Maruyama H,Origasa H,Minematsu K,Uchiyama S,Matsumoto M,J-STARS Collaborators.

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to define the influence of feeding mean arterial pressure (FMAP) in conjunction with other morphological or clinical risk factors in determining the probability of hemorrhagic presentation in patients with cerebral arteriovenous malformations (AVMs). METHODS:Clinical and angiograp...

journal_title：Stroke

authors： Duong DH,Young WL,Vang MC,Sciacca RR,Mast H,Koennecke HC,Hartmann A,Joshi S,Mohr JP,Pile-Spellman J

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In major cerebral arterial steno-occlusive diseases, there can be remarkably decreased hemodynamic reserve without marked neurological impairments. In such settings, it is not known whether the neural activity is well maintained or disturbed according to the severity of cerebral ischemia. The pre...

journal_title：Stroke

authors： Bundo M,Inao S,Nakamura A,Kato T,Ito K,Tadokoro M,Kabeya R,Sugimoto T,Kajita Y,Yoshida J

更新日期：2002-01-01 00:00:00

abstract：:Background and Purpose- Diffusion-weighted imaging (DWI) hyperintensities in intracerebral hemorrhage (ICH) are associated with increased risk of recurrent ICH, cognitive impairment, and death, but whether these lesions are specific to a subtype of ICH remains uncertain. We investigated the association between DWI les...

journal_title：Stroke

authors： Boulanger M,Schneckenburger R,Join-Lambert C,Werring DJ,Wilson D,Hodel J,Zuber M,Touzé E

更新日期：2018-12-07 00:00:00

abstract：:Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...

journal_title：Stroke

authors： Herold S,Frackowiak RS,Neil-Dwyer G

更新日期：1987-01-01 00:00:00

abstract：:We tested the hypothesis that hypertension is more common and cardiac embolism less common in patients with lacunar infarction than in patients with other types of cerebral infarction. We studied risk factor profiles in a series of 102 consecutive patients with a lacunar infarct and 202 consecutive patients with a car...

journal_title：Stroke

authors： Lodder J,Bamford JM,Sandercock PA,Jones LN,Warlow CP

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Do children have an increased risk for brain arteriovenous malformation (AVM) recurrence compared with adults and does this risk vary depending on initial presentation with AVM rupture? METHODS:We retrospectively studied 115 patients initially presenting with brain AVM under age 25 years who und...

journal_title：Stroke

authors： Copelan A,Drocton G,Caton MT,Smith ER,Cooke DL,Nelson J,Abla AA,Fox C,Amans MR,Dowd CF,Halbach VV,Higashida RT,Lawton MT,Kim H,Fullerton HJ,Gupta N,Hetts SW,UCSF Center For Cerebrovascular Research and UCSF Pediatric Br

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Eligibility criteria determine the external validity (generalizability) of the results of randomized controlled trials. To increase the number of outcome events, and hence statistical power, some recent stroke prevention trials have required additional vascular risk factors for eligibility. METH...

journal_title：Stroke

authors： Howard SC,Algra A,Warlow CP,Rothwell PM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-aspartate (NMDA) antagonist therapy, suboptim...

journal_title：Stroke

authors： Onal MZ,Li F,Tatlisumak T,Locke KW,Sandage BW Jr,Fisher M

更新日期：1997-05-01 00:00:00

abstract：:Cerebral blood flow (CBF) was determined in the rat under 70% nitrous oxide anesthesia and pentobarbital anesthesia. The application of the Fick principle technique of Kety et al. was modified utilizing 133Xe infused intravenously steadily for 30 seconds, at which time the animal was decapitated and the head frozen in...

journal_title：Stroke

authors： Matsumoto A,Namon R,Utsunomiya Y,Kogure K,Scheinberg P,Reinmuth OM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral ischemia and stroke are leading causes of morbidity and mortality. An approach to protecting the brain during ischemia is to try to increase the delivery of oxygen via the residual blood flow through and around ischemic tissue. To test this hypothesis, we used a novel oxygen delivery age...

journal_title：Stroke

authors： Watson JC,Doppenberg EM,Bullock MR,Zauner A,Rice MR,Abraham D,Young HF

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Leukocytes have been implicated in the development of ischemic atherosclerotic vascular diseases. In a prospective study we investigated whether the plasma concentrations of inflammatory mediators, ie, proteases and cytokines, as markers for systemic leukocyte activation, are increased in patient...

journal_title：Stroke

authors： Elneihoum AM,Falke P,Axelsson L,Lundberg E,Lindgärde F,Ohlsson K

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of fibrinolysis, and high levels may increase the risk of cardiovascular disease. The 4G/5G polymorphism affects PAI-1 gene transcription with lower levels of plasma PAI-1 in the presence of the 5G allele. We investigated whethe...

journal_title：Stroke

authors： Hoekstra T,Geleijnse JM,Kluft C,Giltay EJ,Kok FJ,Schouten EG

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis. METHODS:We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Web of Science. Twenty-two studies comprisi...

journal_title：Stroke

authors： Gouya G,Arrich J,Wolzt M,Huber K,Verheugt FW,Gurbel PA,Pirker-Kees A,Siller-Matula JM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by...

journal_title：Stroke

authors： Arima H,Huang Y,Wang JG,Heeley E,Delcourt C,Parsons M,Li Q,Neal B,Chalmers J,Anderson C,INTERACT1 Investigators.

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Milk fat globule-EGF factor-8 (MFGE8) has been reported to be neuroprotective in ischemic stroke. However, the effects of MFGE8 in early brain injury after subarachnoid hemorrhage (SAH) have not been investigated. We investigated the role of MFGE8 in early brain injury and the potential mechanism...

journal_title：Stroke

authors： Liu F,Hu Q,Li B,Manaenko A,Chen Y,Tang J,Guo Z,Tang J,Zhang JH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：:A 26-year-old woman had a peripartum venous thrombotic stroke involving the right parietal lobe. The initial thrombus was present only in the right channel of a congenitally bifurcated superior sagittal sinus. This diagnosis and subsequent thrombus extension were readily shown by magnetic resonance imaging in contrast...

journal_title：Stroke

authors： Hosley MA,Fisher M,Lingley JF

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. ...

journal_title：Stroke

authors： Urban PP,Wolf T,Uebele M,Marx JJ,Vogt T,Stoeter P,Bauermann T,Weibrich C,Vucurevic GD,Schneider A,Wissel J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Nimodipine, a calcium antagonist, has been reported to have beneficial effects in acute ischemic infarction. Some calcium channel antagonists have antiplatelet effects. We investigated the effect of oral nimodipine on platelet function in healthy volunteers. METHODS:Twelve healthy volunteers (6 ...

journal_title：Stroke

authors： Feinberg WM,Bruck DC

更新日期：1993-01-01 00:00:00

abstract：:Cerebral autoregulation can be duplicated in vitro using the large middle cerebral arteries from a calf. The limits of autoregulation were between 50 and 150 mm Hg. Excessively high pressures may lead to the appearance of the "sausage- or bead-string" response followed by forced dilation. These results suggest the exi...

journal_title：Stroke

authors： Vinall PE,Simeone FA

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Body mass index has been associated with ischemic stroke in older populations, but its association with stroke in younger populations is not known. In light of the current obesity epidemic in the United States, the potential impact of obesity on stroke risk in young adults deserves attention. ME...

journal_title：Stroke

authors： Mitchell AB,Cole JW,McArdle PF,Cheng YC,Ryan KA,Sparks MJ,Mitchell BD,Kittner SJ

更新日期：2015-06-01 00:00:00

abstract：:Abundant preclinical studies have identified multiple mechanisms of ischemic brain injury and have provided proof of principle that strategies designed to counter these mechanisms can protect the ischemic brain. This review article emphasizes the translation of these strategies from the laboratory to clinical trials. ...

journal_title：Stroke

authors： Ginsberg MD

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic brain injury secondary to an arterial occlusion is characterized by acute local inflammation. Blood polymorphonuclear leukocytes (PMNL), primarily neutrophils, adhere to endothelial cells and rapidly invade the injured brain after the arterial occlusion. This neutrophilic invasion might ...

journal_title：Stroke

authors： Kostulas N,Kivisäkk P,Huang Y,Matusevicius D,Kostulas V,Link H

更新日期：1998-02-01 00:00:00

abstract：:Platinum microelectrodes were used to measure H2 clearance in mouse brain, and the clearance curves were used to calculate regional cerebral blood flow (rCBF). The curves were usually biexponential, whether or not electrode placement was confined to the cortex. When calculated by the height over area method, rCBF in a...

journal_title：Stroke

authors： Rosenblum WI

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Central autonomic dysfunction increases stroke morbidity and mortality. We aimed to investigate whether poststroke autonomic dysfunction graded by Ewing battery can predict clinical outcome. METHODS:In this prospective observational study, we assessed autonomic function of ischemic stroke patien...

journal_title：Stroke

authors： Xiong L,Tian G,Leung H,Soo YOY,Chen X,Ip VHL,Mok VCT,Chu WCW,Wong KS,Leung TWH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Stroke patients are heterogeneous not only with respect to etiology but also in terms of preexisting clinical conditions. Approximately one fifth of patients with acute stroke are hyperglycemic and/or have had a recent infectious or inflammatory condition. Summary of Review-- Experimental research indicates ...

journal_title：Stroke

authors： Kent TA,Soukup VM,Fabian RH

更新日期：2001-10-01 00:00:00