Arterial Stiffness Is Associated With Basal Ganglia Enlarged Perivascular Spaces and Cerebral Small Vessel Disease Load.

abstract：BACKGROUND AND PURPOSE:Wall shear stress (WSS) is one of the main pathogenic factors in the development of saccular cerebral aneurysms. The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD). METHODS:Twenty ma...

journal_title：Stroke

authors： Shojima M,Oshima M,Takagi K,Torii R,Hayakawa M,Katada K,Morita A,Kirino T

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To date, studies on neonatal stroke have mainly focused on cortical stroke. We have focused on perforator strokes, noncortical strokes in the arterial vascular perforator area. We sought to identify risk factors and evaluate clinical presentation and neuroimaging findings for neonatal perforator ...

journal_title：Stroke

authors： Ecury-Goossen GM,Raets MM,Lequin M,Feijen-Roon M,Govaert P,Dudink J

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pivotal National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials excluded patients with ischemic stroke with specific minor presentations or rapidly improving symptoms. The recombinant tissue plasminogen activator product label notes that its use...

journal_title：Stroke

authors： Khatri P,Kleindorfer DO,Yeatts SD,Saver JL,Levine SR,Lyden PD,Moomaw CJ,Palesch YY,Jauch EC,Broderick JP

更新日期：2010-11-01 00:00:00

abstract：:Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

journal_title：Stroke

authors： Fiedler VB,Seuter F,Perzborn E

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent innovations such as CT installation in ambulances may lead to earlier start of stroke-specific treatments. However, such technically complex mobile facilities require effective methods of correctly identifying patients before deployment. We aimed to develop and validate a new dispatcher id...

journal_title：Stroke

authors： Krebes S,Ebinger M,Baumann AM,Kellner PA,Rozanski M,Doepp F,Sobesky J,Gensecke T,Leidel BA,Malzahn U,Wellwood I,Heuschmann PU,Audebert HJ

更新日期：2012-03-01 00:00:00

abstract：:Background and Purpose- In this era of endovascular therapy (EVT) with early, complete recanalization and reperfusion, we have observed an even more rapid apparent diffusion coefficient (ADC) normalization within the acute ischemic lesion compared with the natural history or IV-tPA-treated patient. In this study, we a...

journal_title：Stroke

authors： Hsia AW,Luby M,Cullison K,Burton S,Armonda R,Liu AH,Leigh R,Nadareishvili Z,Benson RT,Lynch JK,Latour LL

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：:MRI is becoming the imaging modality of choice in patients with ischemic cerebrovascular disease although CT is still the test of choice to exclude acute hemorrhagic stroke. We have briefly reviewed characteristic features of ischemic and hemorrhagic cerebrovascular disease as well as vascular anomalies as seen on MRI...

journal_title：Stroke

authors： Ramadan NM,Deveshwar R,Levine SR

更新日期：1989-09-01 00:00:00

abstract：:Four university centers collaborated to contribute 1158 patients with acute episodes of cerebrovascular disease to the pilot Stroke Data Bank, initiated by NINCDS in 1978. During the pilot project a standard set of data collection forms were developed and used at each of the collaborating centers. Data on clinical cou...

journal_title：Stroke

authors： Kunitz SC,Gross CR,Heyman A,Kase CS,Mohr JP,Price TR,Wolf PA

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelial progenitor cells (EPCs) migrate from bone marrow to systemic circulation in response to tissue ischemia where they differentiate into mature endothelial cells for angiogenesis in situ. This study tested the hypothesis that the level of circulating EPCs is substantially increased and p...

journal_title：Stroke

authors： Yip HK,Chang LT,Chang WN,Lu CH,Liou CW,Lan MY,Liu JS,Youssef AA,Chang HW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Release of excitatory amino acids (EAA) is considered a cause of neuronal damage in ischemia. We investigated the sources and mechanisms of EAA release using microdialysis in regions of incomplete ischemia where perfusion was reduced by 50% to 80%, by applying inhibitors of volume-regulated anion...

journal_title：Stroke

authors： Feustel PJ,Jin Y,Kimelberg HK

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy. METHODS:We categorized 71 patients ...

journal_title：Stroke

authors： Jung YH,Jang H,Park SB,Choe YS,Park Y,Kang SH,Lee JM,Kim JS,Kim J,Kim JP,Kim HJ,Na DL,Seo SW

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To prevent new cardiovascular events after stroke, prescribed preventive drugs should be used continuously. This study measures persistent use of preventive drugs after stroke and identifies factors associated with persistence. METHODS:A 1-year cohort (21,077 survivors) from Riks-Stroke, the Swe...

journal_title：Stroke

authors： Glader EL,Sjölander M,Eriksson M,Lundberg M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:National Institutes of Health Stroke Scale (NIHSS) item profiles that were recently proposed and validated may prove useful for clinical prognostication and research studies. We aimed to validate the NIHSS item profiles in hyper-acute stroke patients who received thrombolysis treatment (tissue-ty...

journal_title：Stroke

authors： Abdul-Rahim AH,Fulton RL,Sucharew H,Kleindorfer D,Khatri P,Broderick JP,Lees KR,SITS-MOST Steering Committee.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：:Weights of matching right and left middle or posterior cerebral arteries and their main branches from the same animal were compared 8-10 weeks after unilateral denervation by superior cervical ganglionectomy. When compared in pairs, the denervated arterial systems weighed significantly less (mean 85%) than their inner...

journal_title：Stroke

authors： Bevan RD,Tsuru H,Bevan JA

更新日期：1983-05-01 00:00:00

abstract：:Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patie...

journal_title：Stroke

authors： Lip GYH,Keshishian A,Li X,Hamilton M,Masseria C,Gupta K,Luo X,Mardekian J,Friend K,Nadkarni A,Pan X,Baser O,Deitelzweig S

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reduced arterial distensibility has been introduced as a novel risk factor for atherosclerosis. The importance of the genetic contribution to variation in distensibility is largely unknown. The purpose of this study was to estimate heritability of carotid distensibility. METHODS:The ongoing Nort...

journal_title：Stroke

authors： Juo SH,Rundek T,Lin HF,Cheng R,Lan MY,Huang JS,Boden-Albala B,Sacco RL

更新日期：2005-11-01 00:00:00

abstract：:Two patients with left middle cerebral artery (MCA) distribution infarctions fulfilled the "hot stroke" criteria on sequential 99m Tc pertechnetate flow and static gamma camera studies. The radioisotopic finding of a paradoxical relative increased flow to the affected hemisphere correlated with serial angiography show...

journal_title：Stroke

authors： Yarnell PR,Earnest MP,Sanders B,Burdick D

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cerebrovascular contribution to ischemic preconditioning (IPC) has been scarcely explored. Using in vivo and in vitro approaches, we investigated the involvement of the blood-brain barrier and the role of its cellular components. METHODS:Seven-minute occlusion of the right middle cerebral ar...

journal_title：Stroke

authors： Gesuete R,Orsini F,Zanier ER,Albani D,Deli MA,Bazzoni G,De Simoni MG

更新日期：2011-05-01 00:00:00

abstract：:In a consecutive series of 473 patients admitted within 72 hours after a subarachnoid hemorrhage, 91 (19%) had hydrocephalus on the initial computed tomogram. Consciousness was unimpaired in 25 of the 91 (28%). In 11 more patients acute hydrocephalus developed within 1 week after subarachnoid hemorrhage. Thirty-eight ...

journal_title：Stroke

authors： Hasan D,Vermeulen M,Wijdicks EF,Hijdra A,van Gijn J

更新日期：1989-06-01 00:00:00

abstract：:Reduction in cerebral blood flow (CBF) following global ischemia has been implicated as a pathogenetic mechanism in progressive brain damage seen after restoration of effective cardiac action and cerebral perfusion pressure. There are serious limitations to many of the techniques for measuring regional cerebral blood ...

journal_title：Stroke

authors： Jackson DL,Dole WP,McGloin J,Rosenblatt JI

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Limited data are available on management of outpatients with stroke or transient ischemic attack (TIA) and on clinicians' reasons for withholding procedures recommended by guidelines. We assessed to what extent guidelines are appropriately applied after ischemic stroke or TIA, in admitted patient...

journal_title：Stroke

authors： Scholte op Reimer WJ,Dippel DW,Franke CL,van Oostenbrugge RJ,de Jong G,Hoeks S,Simoons ML

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is a major risk factor for ischemic stroke and its prevalence increases steeply with age. Population-based data on its influence on stroke outcome are scarce. METHODS:We evaluated the prevalence of AF and its influence on prognosis in patients with a first-ever ischemic ...

journal_title：Stroke

authors： Marini C,De Santis F,Sacco S,Russo T,Olivieri L,Totaro R,Carolei A

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to investigate the periprocedural morbidity, mortality, and long-term clinical and angiographic follow-up using stent-assisted coiling and stenting alone for treatment of cranial fusiform dissecting and atherosclerotic aneurysms. METHODS:The Institutional Review Boa...

journal_title：Stroke

authors： Wakhloo AK,Mandell J,Gounis MJ,Brooks C,Linfante I,Winer J,Weaver JP

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Thrombus within the carotid artery usually occurs in vessels with severe atherosclerotic disease and may embolize to cause transient ischemic attacks and cerebral infarctions. The risk factors for carotid artery thrombus formation in the absence of atherosclerosis are not well characterized. A case series is...

journal_title：Stroke

authors： Akins PT,Glenn S,Nemeth PM,Derdeyn CP

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While brain tissue lactate increases during cerebral ischemia and is known to be important in the pathogenesis of ischemic brain injury, patterns of extracellular lactate accumulation have been less well characterized, and the influence of brain temperature has not been previously investigated. M...

journal_title：Stroke

authors： Lin B,Busto R,Globus MY,Martinez E,Ginsberg MD

更新日期：1995-09-01 00:00:00

abstract：:The relationship between central conduction time (CCT) and levels of regional blood flow were studied in 9 primates. Flows were recorded in both hemispheres using the method of hydrogen (2 min) clearance. The somatosensory evoked potentials were recorded over the contralateral cortex and the dorsal columns, following ...

journal_title：Stroke

authors： Hargadine JR,Branston NM,Symon L

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The premotor cortex (PMC) (Brodmann 6) contributes uniquely to proximal upper and lower limb power and plays a role in the organization of motor behaviors. We assessed the degree to which PMC damage affected functional outcome. METHODS:We prospectively compared the functional outcome of patients...

journal_title：Stroke

authors： Miyai I,Suzuki T,Kang J,Kubota K,Volpe BT

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is little reported of the safety and efficacy of high-dose intravenous recombinant tissue plasminogen activator (alteplase) in combination with heparin anticoagulation in patients presenting with acute ischemic stroke. METHODS:Thirty-two patients with severe hemispheric stroke syndrome cau...

journal_title：Stroke

authors： von Kummer R,Hacke W

更新日期：1992-05-01 00:00:00