Abstract:
BACKGROUND AND PURPOSE:To prevent new cardiovascular events after stroke, prescribed preventive drugs should be used continuously. This study measures persistent use of preventive drugs after stroke and identifies factors associated with persistence. METHODS:A 1-year cohort (21,077 survivors) from Riks-Stroke, the Swedish Stroke Register, was linked to the Swedish Prescribed Drug Register. RESULTS:The proportion of patients who were persistent users of drugs prescribed at discharge from hospital declined progressively over the first 2 years to reach 74.2% for antihypertensive drugs, 56.1% for statins, 63.7% for antiplatelet drugs, and 45.0% for warfarin. For most drugs, advanced age, comorbidity, good self-perceived health, absence of low mood, acute treatment in a stroke unit, and institutional living at follow-up were independently associated with persistent medication use. CONCLUSIONS:Persistent secondary prevention treatment declines rapidly during the first 2 years after stroke, particularly for statins and warfarin. Effective interventions to improve persistent secondary prevention after stroke need to be developed.
journal_name
Strokejournal_title
Strokeauthors
Glader EL,Sjölander M,Eriksson M,Lundberg Mdoi
10.1161/STROKEAHA.109.566950subject
Has Abstractpub_date
2010-02-01 00:00:00pages
397-401issue
2eissn
0039-2499issn
1524-4628pii
STROKEAHA.109.566950journal_volume
41pub_type
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