Risk factors, clinical presentation, and neuroimaging findings of neonatal perforator stroke.

abstract：:Continuous-wave (CW) Doppler ultrasound imaging for prediction of arteriogrphic abnormality at the carotid bifurcation was carried out in 195 arteries of 105 patients. The Doppler method had no predictive value when compared to angiographic findings in arteries classified as 0-50% stenosis by Doppler. In 50-75% stenos...

journal_title：Stroke

authors： Weaver RG Jr,Howard G,McKinney WM,Ball MR,Jones AM,Toole JF

更新日期：1980-07-01 00:00:00

abstract：:Background and Purpose- Recanalization with tPA (tissue-type plasminogen activator) is the only pharmacological therapy available for patients with ischemic stroke. However, the percentage of patients who may receive this therapy is limited by the risk of hemorrhagic transformation (HT)-the main complication of ischem...

journal_title：Stroke

authors： García-Yébenes I,García-Culebras A,Peña-Martínez C,Fernández-López D,Díaz-Guzmán J,Negredo P,Avendaño C,Castellanos M,Gasull T,Dávalos A,Moro MA,Lizasoain I

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...

journal_title：Stroke

authors： Thorén M,Azevedo E,Dawson J,Egido JA,Falcou A,Ford GA,Holmin S,Mikulik R,Ollikainen J,Wahlgren N,Ahmed N

更新日期：2017-09-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage (SAH) was induced in baboons by repeated injections of autologous blood into cisterna chiasmatis and cisterna magna, a total of 14-33 ml being injected over 3-4 days. Cerebral blood flow (CBF; 133xenon clearance) and cerebral metabolic rate of oxygen (CMRO2) were measured before, a...

journal_title：Stroke

authors： Sahlin C,Delgado T,Owman C,Svendgaard NA

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic dysfunction, including increased sympathetic drive and blunted baroreflex, has repeatedly been observed in acute stroke. Of clinical importance is that the stroke-related autonomic imbalance seems to be linked to worse outcome after stroke. Here, we discuss the role of baroreflex impair...

journal_title：Stroke

authors： Sykora M,Diedler J,Turcani P,Hacke W,Steiner T

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:We studied prognosis for survival after an initial stroke in 662 patients who survived at least 30 days after onset while taking into account age, sex, the number of neurological deficits from the initial stroke, stroke type, and five selected medical conditions: hypertension, myocardial infarcti...

journal_title：Stroke

authors： Lai SM,Alter M,Friday G,Sobel E

更新日期：1995-11-01 00:00:00

abstract：:Background and Purpose- Prestroke dependence is an exclusion criterion in most trials of endovascular treatment (EVT) for acute ischemic stroke. Little is known about outcomes after EVT in these patients. We compared outcome and safety of EVT between prestroke-dependent and prestroke-independent patients. Methods- We ...

journal_title：Stroke

authors： Goldhoorn RB,Verhagen M,Dippel DWJ,van der Lugt A,Lingsma HF,Roos YBWEM,Majoie CBLM,Vos JA,Boiten J,van Zwam WH,van Oostenbrugge RJ,van den Wijngaard I,MR CLEAN Registry Investigators.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with acute ischemic stroke and intracranial arterial obstructions have a poor prognosis and a high probability of deteriorating at 24 hours. We aimed to evaluate the diagnostic accuracy of power motion mode Doppler (PMD-TCD) compared with CT angiography as standard in diagnosing intracra...

journal_title：Stroke

authors： Brunser AM,Lavados PM,Hoppe A,Lopez J,Valenzuela M,Rivas R

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Systemic inflammatory response syndrome (SIRS) is a generalized inflammatory state. The primary goal of the study was to determine whether differences exist in outcomes in SIRS and non-SIRS intravenous tissue-type plasminogen activator-treated patients. METHODS:Consecutive patients were retrospe...

journal_title：Stroke

authors： Boehme AK,Kapoor N,Albright KC,Lyerly MJ,Rawal PV,Bavarsad Shahripour R,Alvi M,Houston JT,Sisson A,Beasley TM,Alexandrov AW,Alexandrov AV,Miller DW

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prophylactic administration of simvastatin has been shown to protect against brain damage and its long-lasting behavioral consequences in neonatal rats. To establish the drug treatment window, we evaluated the effectiveness of simvastatin administered at different intervals before and after strok...

journal_title：Stroke

authors： Balduini W,Mazzoni E,Carloni S,De Simoni MG,Perego C,Sironi L,Cimino M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accurate data on the distribution of stroke subtypes are essential for understanding the forces driving recent morbidity and mortality trends. The introduction of diagnosis-related groups (DRGs) in the 1980s may have affected the distribution of stroke subtypes as defined by International Classif...

journal_title：Stroke

authors： Derby CA,Lapane KL,Feldman HA,Carleton RA

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that cerebral microembolism detected with transcranial Doppler sonography distal to internal carotid artery stenosis occurs more frequently in recently symptomatic compared with asymptomatic patients. It has remained unclear whether cerebral microembolism also indicates a ...

journal_title：Stroke

authors： Siebler M,Nachtmann A,Sitzer M,Rose G,Kleinschmidt A,Rademacher J,Steinmetz H

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis. METHODS:We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Web of Science. Twenty-two studies comprisi...

journal_title：Stroke

authors： Gouya G,Arrich J,Wolzt M,Huber K,Verheugt FW,Gurbel PA,Pirker-Kees A,Siller-Matula JM

更新日期：2014-02-01 00:00:00

abstract：:Two patients with left middle cerebral artery (MCA) distribution infarctions fulfilled the "hot stroke" criteria on sequential 99m Tc pertechnetate flow and static gamma camera studies. The radioisotopic finding of a paradoxical relative increased flow to the affected hemisphere correlated with serial angiography show...

journal_title：Stroke

authors： Yarnell PR,Earnest MP,Sanders B,Burdick D

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to determine whether release of endothelium-derived relaxing factor (EDRF) from carotid artery in response to acetylcholine is altered by aging. METHODS:Responses were examined in arteries from Wistar rats 6 to 8 months old (young rats), 24 to 26 months old (old rats),...

journal_title：Stroke

authors： Paternò R,Faraci FM,Heistad DD

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aphasia can result in an inability to communicate the presence, location, or intensity of pain. Although visual analogue scales (VASs) exist, it is unknown whether they are useful in assessing pain in individuals with aphasia. The objective was to determine whether those with poststroke aphasia c...

journal_title：Stroke

authors： Korner-Bitensky N,Kehayia E,Tremblay N,Mazer B,Singer F,Tarasuk J

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to investigate whether the Framingham Cardiovascular Risk Profile and carotid artery intima-media thickness are associated with cortical volume and thickness. METHODS:Consecutive subjects participating in a prospective cohort study of aging and mild cognitive impair...

journal_title：Stroke

authors： Cardenas VA,Reed B,Chao LL,Chui H,Sanossian N,DeCarli CC,Mack W,Kramer J,Hodis HN,Yan M,Buonocore MH,Carmichael O,Jagust WJ,Weiner MW

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mech...

journal_title：Stroke

authors： Jiang L,Li W,Mamtilahun M,Song Y,Ma Y,Qu M,Lu Y,He X,Zheng J,Fu Z,Zhang Z,Yang GY,Wang Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial arterial dolichoectasia (IADE) is a poorly understood arteriopathy compared with intracranial atherosclerotic stenosis (ICAS). We aimed to investigate the risk factors of IADE and ICAS and their relationship with neuroimaging markers of cerebral small vessel disease in a population-b...

journal_title：Stroke

authors： Zhai FF,Yan S,Li ML,Han F,Wang Q,Zhou LX,Ni J,Yao M,Zhang SY,Cui LY,Jin ZY,Zhu YC

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulating evidence indicates that a variety of infections contribute to the pathogenesis of atherosclerosis, but there is controversy concerning the impact of Helicobacter pylori infections in atherosclerosis. METHODS:We evaluated seropositivity to H pylori and to its cytotoxin-associated gen...

journal_title：Stroke

authors： Mayr M,Kiechl S,Mendall MA,Willeit J,Wick G,Xu Q

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic-ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology. METHODS:On postnatal day 7, mice wer...

journal_title：Stroke

authors： Ten VS,Wu EX,Tang H,Bradley-Moore M,Fedarau MV,Ratner VI,Stark RI,Gingrich JA,Pinsky DJ

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine-induced reduction in blood pressure (BP) and an unfavorable outcome in acute stroke. We sought to confirm this correlation with and without adjustment for prognostic variables and to investigate ...

journal_title：Stroke

authors： Ahmed N,Näsman P,Wahlgren NG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The proteoglycan versican is an excellent candidate gene for intracranial aneurysms (IAs) because it plays an important role in extracellular matrix assembly and is localized in a previously implicated locus for IAs on chromosome 5q. METHODS:We analyzed all the common variations using 16-tag sin...

journal_title：Stroke

authors： Ruigrok YM,Rinkel GJ,Wijmenga C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Flow Diverters (FD) are a new emerging therapy for intracranial aneurysms. Initial reports focused on the treatment of proximally located aneurysms. We report our experience with FDs in the treatment of aneurysms at and beyond the circle of Willis. METHODS:We treated 30 aneurysms at and beyond t...

journal_title：Stroke

authors： Pistocchi S,Blanc R,Bartolini B,Piotin M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lacunar ischemic stroke accounts for 25% of all ischemic strokes, but the exact etiology is unknown. Numerous pathophysiologies have been proposed, including atheroma and endothelial dysfunction. Models of any of these pathological features would aid understanding of the etiology and help develop...

journal_title：Stroke

authors： Bailey EL,McCulloch J,Sudlow C,Wardlaw JM

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombin-induced clots used in experimental thromboembolic stroke differ from clots forming spontaneously under clinical conditions. We investigated whether this difference influences the efficacy and outcome of thrombolytic treatment. METHODS:In rats, the middle cerebral artery was occluded by ...

journal_title：Stroke

authors： Niessen F,Hilger T,Hoehn M,Hossmann KA

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS:A prospective study involving 121 people with stroke. Data were obtained through structured interviews and as...

journal_title：Stroke

authors： Minet LR,Peterson E,von Koch L,Ytterberg C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lamotrigine (LTG) is an anticonvulsant drug whose mechanism of action may involve the inhibition of glutamate release by blocking voltage-dependent sodium channels. Glutamate neurotoxicity may contribute to cerebral ischemic damage after recovery from cardiac arrest. Thus, LTG may prevent the bra...

journal_title：Stroke

authors： Crumrine RC,Bergstrand K,Cooper AT,Faison WL,Cooper BR

更新日期：1997-11-01 00:00:00