Abstract:
BACKGROUND AND PURPOSE:The purpose of this study was to investigate the periprocedural morbidity, mortality, and long-term clinical and angiographic follow-up using stent-assisted coiling and stenting alone for treatment of cranial fusiform dissecting and atherosclerotic aneurysms.
METHODS:The Institutional Review Board approved the study. A retrospective analysis was performed of 30 fusiform dissecting and atherosclerotic aneurysms treated in 28 patients (20 females; mean age, 52.6 years). Eleven aneurysms (37%) were located in the posterior circulation. Twenty-one (70%) originated from arterial dissection and 4 aneurysms (13%) presented with subarachnoid bleeding. Twenty-four (80%) aneurysms were treated with stents and coils, whereas 6 (20%) were treated with stents alone.
RESULTS:Immediate postprocedural angiograms in 24 aneurysms treated with stent-assisted coiling showed complete occlusion in 12 and subtotal occlusion in 11 aneurysms, whereas no occlusion was seen in one aneurysm and in all 6 aneurysms treated with stents alone. A clinical improvement or stable outcome was achieved in 25 patients (89%). The 2 cases of permanent morbidity included a patient with a finger dysesthesia associated with a perforator stroke and another patient with hemiparesis and aphasia due to a delayed in-stent thrombosis. One patient died after treatment of a giant vertebrobasilar junction aneurysm. Angiographic follow-up was available in 23 of the 27 surviving patients (85%) at a mean of 16.2 months (range, 1 to 108 months). Recanalization in 4 patients (17%) at 3, 5, 24, and 36 months required retreatment in 3. In-stent stenosis of journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.115.009530
更新日期:2015-08-01 00:00:00
abstract::We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.6.953
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.1.33
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this amino acid has been shown to be due to nutritional status and methylenetetrahydrofolate reductase (MTHFR) genotype. METHODS:Under a case-cont...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000032550.90046.38
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Delayed cerebral ischemia and infarction due to reduced CBF remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage. Hypertonic saline (HS) is associated with an increase in CBF. This study explores whether CBF enhancement with HS in patients with poor-grade subarachnoi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.560698
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Short-term elevations in fine particulate matter air pollution (PM2.5) are associated with increased risk of acute cerebrovascular events. Evidence from the peripheral circulation suggests that vascular dysfunction may be a central mechanism. However, the effects of PM2.5 on cerebrovascular funct...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000395
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Repetitive transcranial magnetic stimulation of the primary motor cortex (M1) may improve outcomes after stroke. The aim of this study was to determine the effects of M1 theta burst stimulation (TBS) and standardized motor training on upper-limb function of patients with chronic stroke. METHODS:...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.110.583278
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The present investigation aimed to quantify functional activity in rat brains after long-term recovery from transient forebrain ischemia. METHODS:With the use of the [14C]2-deoxyglucose method, local cerebral glucose utilization was measured in 62 cortical and subcortical brain regions in postis...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.6.1107
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Kinesthesia, the sense of body motion, is essential to proper control and execution of movement. Despite its importance for activities of daily living, no current clinical measures can objectively measure kinesthetic deficits. The goal of this study was to use robotic technology to quantify preva...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.002058
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:"Incidental" MRI white matter (WM) lesions, comprising periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the aging brain. Direct evidence of ischemia associated with incidental WM lesions (WMLs) has been lacking, and their pathogenesis is unresolved. METHODS:A po...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000221308.94473.14
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. METHODS:Ten Catholic churches were randomize...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.115.010678
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.030455
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Questionnaire for Verifying Stroke-Free Status (QVSFS), a method for verifying stroke-free status in participants of clinical, epidemiological, and genetic studies, has not been validated in low-income settings where populations have limited knowledge of stroke symptoms. We aimed to validate ...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.115.010374
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To clarify hemodynamic risk factors for hemorrhage in arteriovenous malformations (AVMs), the mean transit time (MTT) of feeding arteries and draining veins in AVMs with and without hemorrhage was measured and analyzed. METHODS:Morphological features such as the number and diameter of draining a...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.STR.0000089924.43363.E3
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.029942
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth. METHODS:Three raters examined baseline su...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.108.536888
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to assess outcomes after endovascular treatment/therapy of acute ischemic stroke, overall and by subgroups, and looked for predictors of outcome. METHODS:We used data from a mandatory, population-based registry that includes external monitoring of completeness, which assesses reperfusi...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.113.003489
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:European directives and legislation in some countries forbid inclusion of subjects incapable of consent in research if recruitment of patients capable of consent will yield similar results. We compared brain lesion volumes in stroke patients deemed to have capacity to consent with those defined a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.507111
更新日期:2008-08-01 00:00:00
abstract::We measured cerebral blood flow and somatosensory evoked potentials during transient focal cerebral ischemia in cats to compare the effects of four commonly used anesthetic regimens: ketamine/fentanyl/N2O (fentanyl), pentobarbital, ketamine/alpha-chloralose (alpha-chloralose), and ketamine/halothane/N2O (halothane). S...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.5.795
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is evidence of unequal access to health care interventions even where universal health systems operate. We investigated associations between patients' sociodemographic characteristics and the provision of acute and longer-term stroke care in a multiethnic urban population. METHODS:We used ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000152332.32267.19
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:High-dose human albumin (ALB) is robustly neuroprotective in rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of ALB therapy in ischemic stroke. We analyzed the data for preliminary evidence of treatment efficacy. METHODS:Eighty-two subjects with acute isc...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000231389.34701.b5
更新日期:2006-08-01 00:00:00
abstract::Cerebral blood flow was studied in rabbits immediately following complete circulatory stasis of varying duration. Systemic arterial pressure was measured continuously. The postischemic circulation was examined both by an infusion of carbon black and, in separate experiments, by injection of 14C-antipyrine into the blo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.10.4.423
更新日期:1979-07-01 00:00:00
abstract::Background and Purpose- Patients with intracerebral hemorrhage (ICH) and atrial fibrillation (AF) are at risk for ischemic events. While risk calculators (CHA2DS2-VASc and HAS-BLED) have been validated to assess risk for ischemic stroke and major bleeding in AF patients, decisions about anticoagulation must consider t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027370
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is little reported of the safety and efficacy of high-dose intravenous recombinant tissue plasminogen activator (alteplase) in combination with heparin anticoagulation in patients presenting with acute ischemic stroke. METHODS:Thirty-two patients with severe hemispheric stroke syndrome cau...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.23.5.646
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Iron is an essential element for the human body. It has, however, been suggested that excessive iron stores may increase the risk of vascular disease. So far, epidemiologic studies on stroke are sparse. METHODS:We studied the association between iron status and stroke risk in a population-based ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000173172.82880.72
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Delayed cerebral infarction (DCI) is an important cause of poor outcome after subarachnoid hemorrhage. Cerebral perfusion is a predictor for DCI. Because acute hydrocephalus may impair cerebral perfusion, we evaluated the predictive value of the extent of acute hydrocephalus on the development of...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.484220
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The success of gait rehabilitation after stroke depends on active walking exercises. However, the disabling after-effects of stroke often make such exercises impossible at the onset of therapy. To facilitate treadmill training of paraparetic patients, a robot-driven gait orthosis (Lokomat) was de...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/01.STR.0000254607.48765.cb
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Outcome after mechanical thrombectomy for ischemic stroke may be influenced by blood pressure (BP). This study aims to assess the association of BP changes during general anesthesia versus conscious sedation with functional outcome after mechanical thrombectomy. METHODS:SIESTA (Sedation vs Intub...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.117.019709
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The role of the cerebral microcirculation in delayed ischemia after subarachnoid hemorrhage remains obscure. To test the hypothesis that cerebral arterioles have a reduced capacity to dilate after subarachnoid hemorrhage, we studied the microvascular responses to papaverine (PPV) in patients unde...
journal_title:Stroke
pub_type: 信件
doi:10.1161/STROKEAHA.108.522375
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The reproducibility of duplex scan measures of carotid atherosclerosis was evaluated as part of a study assessing the prevalence of carotid disease in elderly adults. METHODS:Doppler measures of blood flow velocity were used to evaluate disease severity, and extent of carotid plaque was scored f...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.2.215
更新日期:1992-02-01 00:00:00