Are there inequalities in the provision of stroke care? Analysis of an inner-city stroke register.

abstract：:Background and Purpose- Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which include PERK (protein kinase RNA-like ER kinase). Activated PERK phosph...

journal_title：Stroke

authors： Wang YC,Li X,Shen Y,Lyu J,Sheng H,Paschen W,Yang W

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Discharge ICD-9-CM (International Classification of Diseases, 9th Revision, Clinical Modification) codes have been used to identify patients with acute stroke for epidemiological, quality of care, and cost studies. The aim of this study was to determine if the accuracy of the primary ICD-9-CM cod...

journal_title：Stroke

authors： Goldstein LB

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is beneficial within 4.5 hours of symptom onset, but the effect rapidly decreases over time, necessitating quick diagnostic in-hospital work-up. Initial time strain occasionally results in treatment of patients with an alternate diagnosis (stroke...

journal_title：Stroke

authors： Zinkstok SM,Engelter ST,Gensicke H,Lyrer PA,Ringleb PA,Artto V,Putaala J,Haapaniemi E,Tatlisumak T,Chen Y,Leys D,Sarikaya H,Michel P,Odier C,Berrouschot J,Arnold M,Heldner MR,Zini A,Fioravanti V,Padjen V,Beslac-Bu

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental stroke models are essential to study in vivo pathophysiological processes of focal cerebral ischemia. In this study, an embolic stroke model in rats was applied (1) to characterize early development of regional cerebral blood flow and metabolism with positron emission tomography (PET...

journal_title：Stroke

authors： Walberer M,Backes H,Rueger MA,Neumaier B,Endepols H,Hoehn M,Fink GR,Schroeter M,Graf R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Of few prospective studies that have focused on the relationship between fibrinogen and ischemic stroke (IS) in Asian populations, the findings were inconsistent with those conducted in Western countries. Therefore, we aimed to investigate the temporal relationship between fibrinogen levels (plus...

journal_title：Stroke

authors： Chuang SY,Bai CH,Chen WH,Lien LM,Pan WH

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...

journal_title：Stroke

authors： Roy D,Soucy JP,Hartman NG,Janicki C,Weill A,Guilbert F,Papineau K,Raymond J

更新日期：2005-11-01 00:00:00

abstract：:Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...

journal_title：Stroke

authors： Atkinson CS,Press GA,Lyden P,Katz B

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is known that atherosclerosis does not involve both carotid arteries to the same extent. Pathological investigations have demonstrated that lesions develop in regions of low wall shear stress. The aims of the present study were to verify the degree of carotid atherosclerosis asymmetry in a pop...

journal_title：Stroke

authors： Gnasso A,Irace C,Carallo C,De Franceschi MS,Motti C,Mattioli PL,Pujia A

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased mean platelet volume (MPV), indicating higher platelet reactivity, is associated with an increased risk of myocardial infarction. Higher levels of MPV have been found in patients with acute ischemic stroke than in control subjects. Data from smaller studies regarding an association betw...

journal_title：Stroke

authors： Greisenegger S,Endler G,Hsieh K,Tentschert S,Mannhalter C,Lalouschek W

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) causes acute vasoconstriction that contributes to ischemic brain injury shortly after the initial bleed. It has been theorized that decreased availability of nitric oxide (NO) may contribute to acute vasoconstriction. Therefore we examined the effect of the NO donor ...

journal_title：Stroke

authors： Sehba FA,Ding WH,Chereshnev I,Bederson JB

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most improvement from poststroke aphasia occurs within the first 3 months, but there remains unexplained variability in recovery. Recently, we reported a strong correlation between initial impairment and change scores in motor recovery at 90 days. We wanted to determine whether aphasia recovery (...

journal_title：Stroke

authors： Lazar RM,Minzer B,Antoniello D,Festa JR,Krakauer JW,Marshall RS

更新日期：2010-07-01 00:00:00

abstract：:We studied the effects of the calcium channel blocker nicardipine on regional tissue Ca2+, Na+, K+, and water shifts in the brains of seven Sprague-Dawley rats after permanent occlusions of the middle cerebral artery. We also assessed the entry of [14C]nicardipine into the brains of five rats; the highest concentratio...

journal_title：Stroke

authors： Hadani M,Young W,Flamm ES

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With decision-analytic models becoming more popular to assess the cost-effectiveness of health care interventions, the need for robust estimates on the costs of cerebrovascular disease is paramount. This study reports the results from a literature review of the costs of cerebrovascular diseases, ...

journal_title：Stroke

authors： Luengo-Fernandez R,Gray AM,Rothwell PM

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined whether hemodynamic and metabolic abnormalities in the cerebral white matter, basal ganglia, and thalamus are associated with asymptomatic white matter lesions (WML) depicted on MR images. METHODS:A positron emission tomographic study with H2(15)O, C15O, and 15O2 was performed in eig...

journal_title：Stroke

authors： Hatazawa J,Shimosegawa E,Satoh T,Toyoshima H,Okudera T

更新日期：1997-10-01 00:00:00

abstract：:Perioperative cerebral infarction occurs in less than 1% of general surgical procedures; the mechanism is usually unknown. The clinical features of 12 consecutive perioperative strokes were retrospectively reviewed. Although intraoperative hypotension was frequent, onset of deficit occurred postoperatively in 83% and ...

journal_title：Stroke

authors： Hart R,Hindman B

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:MRI characterization of carotid plaque has been studied recently as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a systematic review and meta-analysis to summarize the association of MRI-determined intraplaque hemorrhage, lipid-rich necrotic core, and thinnin...

journal_title：Stroke

authors： Gupta A,Baradaran H,Schweitzer AD,Kamel H,Pandya A,Delgado D,Dunning A,Mushlin AI,Sanelli PC

更新日期：2013-11-01 00:00:00

abstract：:Brief episodes of ischemia can protect against subsequent damaging ischemic events; however, the molecular mechanisms responsible for protection are poorly understood. Identifying genes involved in this process could provide insight into cell survival and treatment of stroke. We developed a murine model of ischemic pr...

journal_title：Stroke

authors： Stenzel-Poore MP,Stevens SL,Simon RP

更新日期：2004-11-01 00:00:00

abstract：:The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...

journal_title：Stroke

authors： Schenk EA,Bond MG,Aretz TH,Angelo JN,Choi HY,Rynalski T,Gustafson NF,Berson AS,Ricotta JJ,Goodison MW

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Attained height, an indicator of genetic potential and childhood growth environment, is inversely associated with stroke, but the mechanisms are poorly understood. We investigated whether childhood height and growth are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH). MET...

journal_title：Stroke

authors： Gjærde LK,Truelsen TC,Baker JL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While it has been widely reported that the vasospasm following subarachnoid hemorrhage (SAH) is prevented/reversed by endothelin (ET) receptor antagonists selective for the ET(A) receptor and by nonselective ET receptor antagonists, ie, antagonists of both the ET(A) and ET(B) receptors, there are...

journal_title：Stroke

authors： Zuccarello M,Boccaletti R,Romano A,Rapoport RM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several hundred small RNAs called microRNAs (miRNAs) have been identified and characterized from various organisms, including humans. In humans, some of these miRNAs have been found to regulate (patho)physiologic conditions such as tumor progression/regression, cholesterol and glucose homeostasis...

journal_title：Stroke

authors： Jeyaseelan K,Lim KY,Armugam A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Body mass index has been associated with ischemic stroke in older populations, but its association with stroke in younger populations is not known. In light of the current obesity epidemic in the United States, the potential impact of obesity on stroke risk in young adults deserves attention. ME...

journal_title：Stroke

authors： Mitchell AB,Cole JW,McArdle PF,Cheng YC,Ryan KA,Sparks MJ,Mitchell BD,Kittner SJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis for acute ischemic stroke in patients aged > 80 years is not approved in some countries due to limited trial data in the very elderly. We compared outcomes between thrombolysed and nonthrombolysed (control) patients from neuroprotection trials to assess any influence of age on respon...

journal_title：Stroke

authors： Mishra NK,Diener HC,Lyden PD,Bluhmki E,Lees KR,VISTA Collaborators.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The perfusion territories of the brain-feeding arteries are difficult to assess in vivo and therefore standard cerebral perfusion territory templates are often used to determine the relation between cerebral infarcts and the feeding vasculature. In the present study, we compared this infarct clas...

journal_title：Stroke

authors： Hendrikse J,Petersen ET,Chèze A,Chng SM,Venketasubramanian N,Golay X

更新日期：2009-05-01 00:00:00

abstract：:Endothelium dysfunction may result from increased production of reactive oxygen species and decreased availability of nitric oxide. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (ie, statins) exert cholesterol-independent vasoprotective effects that are mediated, in part, through the inhibiti...

journal_title：Stroke

authors： Endres M,Laufs U

更新日期：2004-11-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：:Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...

journal_title：Stroke

authors： Herold S,Frackowiak RS,Neil-Dwyer G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans. METHODS:Patients with suspected TIA underwent acute brain perfusion ...

journal_title：Stroke

authors： Bivard A,Lillicrap T,Maréchal B,Garcia-Esperon C,Holliday E,Krishnamurthy V,Levi CR,Parsons M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic stroke patients often have intracranial atherosclerosis (ICAS), despite heterogeneity in the cause of stroke. We tested the hypothesis that ICAS burden can independently reflect the risk of long-term vascular outcome. METHODS:This was a retrospective cohort study analyzing data from a p...

journal_title：Stroke

authors： Kim BS,Chung PW,Park KY,Won HH,Bang OY,Chung CS,Lee KH,Kim GM

更新日期：2017-10-01 00:00:00

abstract：:Patients with symptoms of cerebral ischemia are often evaluated with non-invasive carotid artery testing. An abnormal carotid Doppler ultrasound frequency shift pattern of early systolic flutter (ESF) was demonstrated by auscultation and velocity wave form analysis in patients with normal carotid bifurcations. Ten of ...

journal_title：Stroke

authors： Weinberger J,Goldman M

更新日期：1985-11-01 00:00:00