Mechanisms of perioperative cerebral infarction.

abstract：BACKGROUND AND PURPOSE:The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS:Seventeen patients with borderzone i...

journal_title：Stroke

authors： Chaves CJ,Silver B,Schlaug G,Dashe J,Caplan LR,Warach S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cerebral vasodilating effect of acetazolamide (ACZ) injection has been used as an index of the autoregulatory vasodilation (or cerebral perfusion reserve). The question of whether the ACZ test assesses the maximal autoregulatory vasodilating capacity is not definitely resolved. The effects of...

journal_title：Stroke

authors： Démolis P,Florence G,Thomas L,Tran Dinh YR,Giudicelli JF,Seylaz J,Alkayed NJ

更新日期：2000-02-01 00:00:00

abstract：:A woman who presented with a subarachnoid hemorrhage secondary to a ruptured anterior spinal artery aneurysm of the spinal cord is reported. While this is the first report of a ruptured aneurysm of the anterior spinal artery with angiographic confirmation, it emphasizes that occasionally subarachnoid hemorrhage may be...

journal_title：Stroke

authors： Vincent FM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown. METHODS:we genotyped single nucleotide polymorphisms (...

journal_title：Stroke

authors： Ronald J,Rajagopalan R,Cerrato F,Nord AS,Hatsukami T,Kohler T,Marcovina S,Heagerty P,Jarvik GP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations...

journal_title：Stroke

authors： Sato S,Delcourt C,Heeley E,Arima H,Zhang S,Al-Shahi Salman R,Stapf C,Woo D,Flaherty ML,Vagal A,Levi C,Davies L,Wang J,Robinson T,Lavados PM,Lindley RI,Chalmers J,Anderson CS,INTERACT2 Investigators.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. METHODS:This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 20...

journal_title：Stroke

authors： El Husseini N,Goldstein LB,Peterson ED,Zhao X,Pan W,Olson DM,Zimmer LO,Williams JW Jr,Bushnell C,Laskowitz DT

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I). We tested the hypothesis that topical pretreatment with the selective potassium channel agonists NS1619 and aprikalim preserves the vasc...

journal_title：Stroke

authors： Veltkamp R,Domoki F,Bari F,Busija DW

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis and quantification of microangiopathy in dementia is difficult. The assessment of small-vessel disease requires expensive and sophisticated nuclear medicine techniques. This study was performed to identify microangiopathy related to the integrity of cerebral microcirculation by sono...

journal_title：Stroke

authors： Puls I,Hauck K,Demuth K,Horowski A,Schliesser M,Dörfler P,Scheel P,Toyka KV,Reiners K,Schöning M,Becker G

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chinese patients largely experience acute ischemic stroke (AIS) because of large artery atherosclerosis rather than cardioembolism, and whether tirofiban is safe and effective in these patients treated with endovascular thrombectomy (ET) is unknown. This study evaluated the safety and efficacy of...

journal_title：Stroke

authors： Zhao W,Che R,Shang S,Wu C,Li C,Wu L,Chen J,Duan J,Song H,Zhang H,Ling F,Wang Y,Liebeskind D,Feng W,Ji X

更新日期：2017-12-01 00:00:00

abstract：:Correlations between changes in regional, cortical, cerebral blood flow (rCBF) and histological changes in the corresponding brain regions were examined following middle cerebral arterial occlusion in 24 cats. In all animals, the duration of arterial occlusion was 2 hours followed by 2 hours of recirculation. The anim...

journal_title：Stroke

authors： Tamura A,Asano T,Sano K

更新日期：1980-09-01 00:00:00

abstract：:We have studied a new high-affinity competitive N-methyl-D-aspartate antagonist, D-CPP-ene (SDZ-EAA 494), in two models of focal cerebral ischemia. In the cat middle cerebral artery occlusion model (6 hours' survival), pretreatment with D-CPP-ene reduced infarct size by 64% (15 mg/kg dose) and 60% (4.5 mg/kg dose). Th...

journal_title：Stroke

authors： Bullock R,McCulloch J,Graham DI,Lowe D,Chen MH,Teasdale GM

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Malignant cerebellar edema (MCE) is a life-threatening complication of acute ischemic stroke that requires timely diagnosis and management. Aim of this study was to identify imaging predictors in initial multiparametric computed tomography (CT), including whole-brain CT perfusion (WB-CTP). METHO...

journal_title：Stroke

authors： Fabritius MP,Thierfelder KM,Meinel FG,Othman AE,Dorn F,Sabel BO,Scheffler P,Ertl-Wagner B,Sommer WH,Kunz WG

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data are scarce on both stroke incidence rates and outcomes in Greece and in rural areas in particular. We performed a prospective population-based study evaluating the incidence of first-ever stroke in the Evros prefecture, a region of a total 147 947 residents located in North Eastern Greece. ...

journal_title：Stroke

authors： Tsivgoulis G,Patousi A,Pikilidou M,Birbilis T,Katsanos AH,Mantatzis M,Asimis A,Papanas N,Skendros P,Terzoudi A,Karamanli A,Kouroumichakis I,Zebekakis P,Maltezos E,Piperidou C,Vadikolias K,Heliopoulos I

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk factors for stroke recurrence have usually been evaluated as single variables. This study is a multivariate analysis of five risk factors (hypertension, myocardial infarction, cardiac arrhythmia, diabetes mellitus, and transient ischemic attacks) for second stroke after an initial ischemic s...

journal_title：Stroke

authors： Lai SM,Alter M,Friday G,Sobel E

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Adequate control of blood pressure (BP) is a cornerstone in stroke prevention. This study explored the risk of stroke in relation to the quality of BP control in a population-based cohort and whether control of hypertension was related to background characteristics of patients. METHODS:A total o...

journal_title：Stroke

authors： Li C,Engström G,Hedblad B,Berglund G,Janzon L

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microvascular basal lamina damage occurs after cerebral ischemia and is important for the development of hemorrhage. The aim of this study was to determine whether hypothermia could maintain microvascular integrity in ischemic stroke. METHODS:Using the suture model, we subjected 12 rats to 3 hou...

journal_title：Stroke

authors： Hamann GF,Burggraf D,Martens HK,Liebetrau M,Jäger G,Wunderlich N,DeGeorgia M,Krieger DW

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to establish the pattern of blood pressure (BP) change after hospitalization for acute hemispheric stroke. METHODS:In 292 patients from the Leicester teaching hospitals with acute hemispheric stroke within the previous 24 hours (139 men; median age, 75 years [range, 42 to 98 years]), w...

journal_title：Stroke

authors： Harper G,Castleden CM,Potter JF

更新日期：1994-09-01 00:00:00

abstract：:This study was conducted to determine whether air distributed to the cerebral circulation alone could cause acute cardiovascular dysfunction and thus be a potential mechanism for sudden death following arterial air embolism. Cardiovascular measurements were made in anesthetized, ventilated cats during infusion of air ...

journal_title：Stroke

authors： Evans DE,Kobrine AI,Weathersby PK,Bradley ME

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces in the brain are common but generally overlooked and of uncertain pathophysiology. They may reflect underlying cerebral small vessel disease. We determined whether enlarged perivascular spaces were associated with lacunar stroke subtype and white matter hyperintensiti...

journal_title：Stroke

authors： Doubal FN,MacLullich AM,Ferguson KJ,Dennis MS,Wardlaw JM

更新日期：2010-03-01 00:00:00

abstract：:The gerbil model was used to assess the therapeutic effects of the calcium antagonist nimodipine on cerebral ischemia. Transient cerebral ischemia was produced in each gerbil by bilateral common carotid occlusion of 10-, 15- or 20-min duration. Nimodipine (0.01 or 0.1 mg/kg) was administered intraperitoneally just bef...

journal_title：Stroke

authors： Fujisawa A,Matsumoto M,Matsuyama T,Ueda H,Wanaka A,Yoneda S,Kimura K,Kamada T

更新日期：1986-07-01 00:00:00

abstract：:Of 171 patients evaluated prospectively and consecutively for cerebral ischemia, 26 (15%) developed symptoms while hospitalized. Cerebral ischemia complicated operative procedures in 12 patients, unsuccessful cardioversion in one and coronary angiography in another. Twelve patients had apparent cerebral embolism and 1...

journal_title：Stroke

authors： Kelley RE,Kovacs AG

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute stroke care, rapid but careful evaluation of patients is mandatory but requires an experienced stroke neurologist. Telemedicine offers the possibility of bringing such expertise quickly to more patients. This study tested for the first time whether remote video examination is feasible an...

journal_title：Stroke

authors： Handschu R,Littmann R,Reulbach U,Gaul C,Heckmann JG,Neundörfer B,Scibor M

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

journal_title：Stroke

authors： Rothwell PM,Slattery J,Warlow CP

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective efficacy of an intravenous formulation of the antioxidant ebselen has been comprehensively assessed with specific regard to conventional quantitative histopathology, subcortical axonal damage, neurological deficit, and principal mechanism of action. METHODS:Transient focal is...

journal_title：Stroke

authors： Imai H,Masayasu H,Dewar D,Graham DI,Macrae IM

更新日期：2001-09-01 00:00:00

abstract：:Among 21 patients with angiographically demonstrated stenosis of the middle cerebral artery (MCA) 14 presented with a stroke and 7 with transient ischaemic attacks (TIAs). Of the former 4 had further strokes (3 fatal); of the latter one had a fatal stroke. Only 2 of the 21 patients had TIAs during the follow-up period...

journal_title：Stroke

authors： Corston RN,Kendall BE,Marshall J

更新日期：1984-03-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to evaluate the impact of new treatments by examining the changes between 1990 to 1991 and 2000 to 2001 in in-hospital mortality rates and hospital charges in adult patients with stroke. METHODS:From the Nationwide Inpatient Survey, the largest all-payer inpatient c...

journal_title：Stroke

authors： Qureshi AI,Suri MF,Nasar A,Kirmani JF,Ezzeddine MA,Divani AA,Giles WH

更新日期：2007-07-01 00:00:00

abstract：:The plasma concentrations of protein C, an anticoagulant protein, and fibrinopeptide A were measured in 37 patients with acute hemispheric stroke and in age-matched controls with nonvascular neurologic diseases. In 11 stroke patients who died within 15 days after the onset (nonsurvivors) protein C antigen concentratio...

journal_title：Stroke

authors： D'Angelo A,Landi G,Vigano'D'Angelo S,Nobile Orazio E,Boccardi E,Candelise L,Mannucci PM

更新日期：1988-05-01 00:00:00

abstract：:Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...

journal_title：Stroke

authors： Atkinson CS,Press GA,Lyden P,Katz B

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the stroke rate associated with atrial fibrillation has declined over the last 10 years, the emerging atrial fibrillation epidemic threatens to increase the incidence of cardioembolic stroke. Summary of Review-Oral anticoagulants are superior antithrombotic agents but are underused due t...

journal_title：Stroke

authors： Medi C,Hankey GJ,Freedman SB

更新日期：2010-11-01 00:00:00