Cardiovascular effects of cerebral air embolism.

abstract：BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...

journal_title：Stroke

authors： Sabri M,Ai J,Macdonald RL

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Matrix metalloproteinases (MMPs) and cysteine proteases (calpain and cathepsin B) play an important role in cell death and are upregulated after focal cerebral ischemia. Because there is a significant interaction between MMP-9 with calpain and cathepsin B, we investigated the role of E64d (a calp...

journal_title：Stroke

authors： Tsubokawa T,Solaroglu I,Yatsushige H,Cahill J,Yata K,Zhang JH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Controlled multicenter studies have demonstrated the efficacy of systemic recombinant tissue-type plasminogen activator (rtPA) treatment in selected cases of acute ischemic stroke. The feasibility of this therapeutic option in clinical practice was assessed in a community-based approach. METHODS...

journal_title：Stroke

authors： Grond M,Stenzel C,Schmülling S,Rudolf J,Neveling M,Lechleuthner A,Schneweis S,Heiss WD

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Stroke patients are heterogeneous not only with respect to etiology but also in terms of preexisting clinical conditions. Approximately one fifth of patients with acute stroke are hyperglycemic and/or have had a recent infectious or inflammatory condition. Summary of Review-- Experimental research indicates ...

journal_title：Stroke

authors： Kent TA,Soukup VM,Fabian RH

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national database. METHODS:Patients between the ages of 1 and 17 years, entered in the Nationwide Inpatient Sample between 2000 and 2003, with Inter...

journal_title：Stroke

authors： Janjua N,Nasar A,Lynch JK,Qureshi AI

更新日期：2007-06-01 00:00:00

abstract：:Background and Purpose- Absent or diminished α-galactosidase A (GLA) and acid α-glucosidase (GAA) enzyme activity are core features of Fabry and Pompe disease, respectively. Patients with Fabry or Pompe disease may have dilated intracranial arteries but whether lower GLA or GAA enzyme activity relates to brain arteria...

journal_title：Stroke

authors： Shah H,Liong C,Levy OA,Waters C,Fahn S,Marder K,Kang UJ,Wolf P,Oliva P,Zhang K,Alcalay RN,Gutierrez J

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with stroke and patients with transient ischemic attack (TIA) are at high risk for vascular events and may not exhibit the signs and symptoms of peripheral arterial disease (PAD). We investigated if asymptomatic PAD detected by ankle brachial index <0.9 is independently associated with r...

journal_title：Stroke

authors： Sen S,Lynch DR Jr,Kaltsas E,Simmons J,Tan WA,Kim J,Beck J,Rosamond W

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We analyzed the impact of detailed anatomic characteristics on the results of endovascular coil embolization for anterior communicating artery (AcoA) aneurysms and developed a predictive model estimating the probability of successful endovascular treatment. METHODS:One hundred eighty-one AcoA an...

journal_title：Stroke

authors： Gonzalez N,Sedrak M,Martin N,Vinuela F

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CADASIL is a newly recognized cause of subcortical ischemic strokes that progressively leads to dementia associated with pseudobulbar palsy and severe motor disability. This deleterious progression and the severity of clinical presentation are widely variable among affected subjects. The exact ro...

journal_title：Stroke

authors： Chabriat H,Pappata S,Poupon C,Clark CA,Vahedi K,Poupon F,Mangin JF,Pachot-Clouard M,Jobert A,Le Bihan D,Bousser MG

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent evidence suggests that physiological changes in the concentration of endogenous estrogens may influence stroke outcome. The purpose of this study was to determine a menstrual cycle-related profile of blood flow through the carotid arteries and its correlation with estrogen concentration. ...

journal_title：Stroke

authors： Krejza J,Mariak Z,Huba M,Wolczynski S,Lewko J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is associated with increased risk of dementia. There has been a decline in mortality from stroke among persons 65 and over in recent decades in the US. It is not clear, however, how this process has affected incidence of various dementias. METHODS:We evaluated over time changes in stroke ...

journal_title：Stroke

authors： Ukraintseva S,Sloan F,Arbeev K,Yashin A

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pivotal National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials excluded patients with ischemic stroke with specific minor presentations or rapidly improving symptoms. The recombinant tissue plasminogen activator product label notes that its use...

journal_title：Stroke

authors： Khatri P,Kleindorfer DO,Yeatts SD,Saver JL,Levine SR,Lyden PD,Moomaw CJ,Palesch YY,Jauch EC,Broderick JP

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a major cause of death in the People's Republic of China (PRC), and the geographic distribution of stroke death varies substantially. We conducted an ecological analysis to investigate the relationship of prevalence of hypertension and other risk factors with stroke incidence and mortal...

journal_title：Stroke

authors： He J,Klag MJ,Wu Z,Whelton PK

更新日期：1995-12-01 00:00:00

abstract：:The frequency of angiographically defined asymptomatic CAD in patients with carotid disease is 40%. Although the prognosis of patients with asymptomatic 1-vessel or 2-vessel CAD is good (annual cardiac mortality rate less than 2%), the prognosis of asymptomatic 3-vessel disease or left main CAD is substantially less f...

journal_title：Stroke

authors： Chimowitz MI,Mancini GB

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A potential way to improve prehospital stroke care and patient handoff is hospital-directed feedback for emergency medical service (EMS) providers. We evaluated whether a hospital-directed EMS stroke follow-up tool improved documentation of adherence to the Rhode Island state prehospital stroke p...

journal_title：Stroke

authors： Choi B,Tsai D,McGillivray CG,Amedee C,Sarafin JA,Silver B

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

journal_title：Stroke

authors： Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Methods of performing and reporting randomized clinical trials (RCTs) are available, but weaknesses still occur. For observational studies, methodology is less well described, and weaknesses are even more likely. In recent guidelines for patients with subarachnoid hemorrhage (SAH), 25% of treatme...

journal_title：Stroke

authors： van der Schaaf IC,Ruigrok YM,Rinkel GJ,Algra A,van Gijn J

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patent foramen ovale (PFO) may increase the risk of embolic stroke of undetermined source (ESUS). Guidelines suggest anticoagulation may be more effective than antiplatelets in preventing stroke in patients with ESUS and PFO when interventional closure is not performed. METHODS:Patients with ESU...

journal_title：Stroke

authors： Diener HC,Chutinet A,Easton JD,Granger CB,Kleine E,Marquardt L,Meyerhoff J,Zini A,Sacco RL

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...

journal_title：Stroke

authors： Muhonen MG,Sawin PD,Loftus CM,Heistad DD

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Improvements in cardiac surgery mortality and morbidity have focused interest on the neurological injury such as stroke and cognitive decline that may accompany an otherwise successful operation. We aimed to investigate (1) the rate of stroke, new ischemic change on MRI, and cognitive impairment ...

journal_title：Stroke

authors： Barber PA,Hach S,Tippett LJ,Ross L,Merry AF,Milsom P

更新日期：2008-05-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Determination of vasomotor reserve (VMR) with the transcranial Doppler-CO(2) (TCD-CO(2)) test is used to assess the risk of impending cerebral ischemia in patients with high-grade stenosis or occlusion of the internal carotid artery. In patients with a poor temporal window, however, this examinat...

journal_title：Stroke

authors： Rohrberg M,Brodhun R

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We hypothesize that reversal in diffusion-weighted imaging (DWI) volume at 24 hours predicts favorable clinical outcome only if accompanied by immediate reperfusion. Our aim was to quantify the immediate DWI and mean transit time changes at 2 and 24 hours after intravenous tissue-type plasminogen...

journal_title：Stroke

authors： Luby M,Warach SJ,Nadareishvili Z,Merino JG

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. ...

journal_title：Stroke

authors： Urban PP,Wolf T,Uebele M,Marx JJ,Vogt T,Stoeter P,Bauermann T,Weibrich C,Vucurevic GD,Schneider A,Wissel J

更新日期：2010-09-01 00:00:00

abstract：:Continuous-wave (CW) Doppler ultrasound imaging for prediction of arteriogrphic abnormality at the carotid bifurcation was carried out in 195 arteries of 105 patients. The Doppler method had no predictive value when compared to angiographic findings in arteries classified as 0-50% stenosis by Doppler. In 50-75% stenos...

journal_title：Stroke

authors： Weaver RG Jr,Howard G,McKinney WM,Ball MR,Jones AM,Toole JF

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Eligibility criteria determine the external validity (generalizability) of the results of randomized controlled trials. To increase the number of outcome events, and hence statistical power, some recent stroke prevention trials have required additional vascular risk factors for eligibility. METH...

journal_title：Stroke

authors： Howard SC,Algra A,Warlow CP,Rothwell PM

更新日期：2006-01-01 00:00:00

abstract：:An overview of the possible factors that might contribute to the development of cerebral vasospasm is presented, with particular emphasis on the possibility that spasm arises from a malfunction of the regulatory or contractile processes in smooth muscle cells. This possibility is emphasized because the evidence for ce...

journal_title：Stroke

authors： Wellum GR,Peterson JW,Zervas NT

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess brain perfusion with an ultrasound contrast-specific imaging mode and to prove if the results are comparable between 2 centers using a standardized study protocol. METHODS:A total of 32 individuals without known cerebrovascular disease were included in the...

journal_title：Stroke

authors： Hölscher T,Wilkening W,Draganski B,Meves SH,Eyding J,Voit H,Bogdahn U,Przuntek H,Postert T

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The trends in stroke incidence reported so far have not been entirely consistent, although declining trends in mortality from stroke have been reported from a number of studies around the world. This study aims to evaluate the 10-year trends (from 1983 through 1992) in incidence, attack rate, and...

journal_title：Stroke

authors： Tuomilehto J,Rastenyte D,Sivenius J,Sarti C,Immonen-Räihä P,Kaarsalo E,Kuulasmaa K,Narva EV,Salomaa V,Salmi K,Torppa J

更新日期：1996-05-01 00:00:00