Stroke in the People's Republic of China. I. Geographic variations in incidence and risk factors.

Abstract:

BACKGROUND AND PURPOSE:Stroke is a major cause of death in the People's Republic of China (PRC), and the geographic distribution of stroke death varies substantially. We conducted an ecological analysis to investigate the relationship of prevalence of hypertension and other risk factors with stroke incidence and mortality in the PRC. METHODS:The relationship between prevalence of risk factors and stroke incidence and mortality in the PRC was assessed in 29 provinces by examining risk factor data from PRC national surveys and incidence and mortality from the 1986 PRC National Stroke Study. RESULTS:A highly statistically significant correlation between prevalence of hypertension and stroke incidence (r = .838, P < .001) and mortality (r = .841, P < .001) was observed. Prevalence of hypertension explained over 70% of the geographic variability in stroke incidence (partial R2 = .703) and mortality (partial R2 = .707) in the PRC. There was a north-south gradient, with a higher prevalence of hypertension and stroke incidence and mortality in the north compared with the south of the country. In multiple Poisson regression analysis, a 10% increase in the prevalence of hypertension was associated with a 2.80-fold higher incidence and 2.68-fold higher mortality from stroke, whereas a 10% increase in the prevalence of alcohol consumption was associated with a 29% higher incidence and a 16% higher mortality from stroke. A 10% increase in the prevalence of cigarette smoking was associated with a 19% higher mortality from stroke. CONCLUSIONS:In the PRC, the prevalence of hypertension is strongly associated with the risk of stroke, and the geographic variation in stroke incidence and mortality is due mainly to differences in the prevalence of hypertension.

journal_name

Stroke

journal_title

Stroke

authors

He J,Klag MJ,Wu Z,Whelton PK

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

2222-7

issue

12

eissn

0039-2499

issn

1524-4628

journal_volume

26

pub_type

杂志文章

相关文献

STROKE文献大全
  • Damage to the Left Precentral Gyrus Is Associated With Apraxia of Speech in Acute Stroke.

    abstract:BACKGROUND AND PURPOSE:Apraxia of speech (AOS) is a motor speech disorder, which is clinically characterized by the combination of phonemic segmental changes and articulatory distortions. AOS has been believed to arise from impairment in motor speech planning/programming and differentiated from both aphasia and dysarth...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.010402

    authors: Itabashi R,Nishio Y,Kataoka Y,Yazawa Y,Furui E,Matsuda M,Mori E

    更新日期:2016-01-01 00:00:00

  • Evaluation of genetic risk factors for silent brain infarction.

    abstract:BACKGROUND AND PURPOSE:Silent brain infarction (SBI) is often found with white matter hyperintensity. A recent genetic study on elderly twins indicated that the susceptibility to white matter hyperintensity was largely determined by genetic factors, implying the existence of genetic susceptibility for SBI as well. We t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.9.1881

    authors: Notsu Y,Nabika T,Park HY,Masuda J,Kobayashi S

    更新日期:1999-09-01 00:00:00

  • New-onset constipation at acute stage after first stroke: incidence, risk factors, and impact on the stroke outcome.

    abstract:BACKGROUND AND PURPOSE:The prevalence of constipation after stroke varies from 30% to 60%. The incidence of new-onset constipation during the early stage of stroke remains uncertain. The present study was designed to investigate the prevalence of new-onset constipation, its risk factors, and its impact on stroke outcom...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.108.534776

    authors: Su Y,Zhang X,Zeng J,Pei Z,Cheung RT,Zhou QP,Ling L,Yu J,Tan J,Zhang Z

    更新日期:2009-04-01 00:00:00

  • Evidence for platelet-activating factor as a novel mediator in experimental stroke in rabbits.

    abstract::Platelet-activating factor is a potent mediator of inflammation, which has untoward effects on cerebrovascular and neural elements. While several investigators have reported attenuation of ischemic damage after treatment with antagonists of platelet-activating factor, no study has proved endogenous production of plate...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.21.10.1452

    authors: Lindsberg PJ,Yue TL,Frerichs KU,Hallenbeck JM,Feuerstein G

    更新日期:1990-10-01 00:00:00

  • Utility of Computed Tomographic Perfusion in Thrombolysis for Minor Stroke.

    abstract:BACKGROUND AND PURPOSE:The use of thrombolysis in acute minor ischemic stroke (MIS) remains controversial. We sought to determine the safety and efficacy of intravenous tissue-type plasminogen activator (IV-tPA) in acute MIS patients with demonstrable penumbra on computed tomographic perfusion study. METHODS:Consecuti...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013021

    authors: Ng FC,Coote S,Frost T,Bladin C,Choi PM

    更新日期:2016-07-01 00:00:00

  • Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder.

    abstract:BACKGROUND AND PURPOSE:Brain microbleeds (MBs) are considered to be associated with cognitive decline and can be pathologically and topographically classified as cerebral amyloid angiopathy-related (located in lobar regions) and hypertensive microangiopathy-related (located in deep regions). We examined whether differe...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.647065

    authors: Yakushiji Y,Noguchi T,Hara M,Nishihara M,Eriguchi M,Nanri Y,Nishiyama M,Hirotsu T,Nakajima J,Kuroda Y,Hara H

    更新日期:2012-07-01 00:00:00

  • Ischemia reduces CGRP-induced cerebral vascular dilation in piglets.

    abstract:BACKGROUND AND PURPOSE:Effects of anoxic stress on cerebrovascular responses to calcitonin gene-related peptide (CGRP) have not been examined previously. We determined the effects of total global ischemia on cerebral arteriolar responses to CGRP in newborn pigs. METHODS:Piglets were anesthetized and ventilated with a ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.27.1.134

    authors: Louis TM,Meng W,Bari F,Errico RA,Busija DW

    更新日期:1996-01-01 00:00:00

  • Ischemic brain damage is not ameliorated by 1,3-butanediol in hyperglycemic rats.

    abstract:BACKGROUND AND PURPOSE:Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage a...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.23.5.719

    authors: Lundgren J,Smith ML,Mans AM,Siesjö BK

    更新日期:1992-05-01 00:00:00

  • MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion.

    abstract:BACKGROUND AND PURPOSE:Several hundred small RNAs called microRNAs (miRNAs) have been identified and characterized from various organisms, including humans. In humans, some of these miRNAs have been found to regulate (patho)physiologic conditions such as tumor progression/regression, cholesterol and glucose homeostasis...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.107.500736

    authors: Jeyaseelan K,Lim KY,Armugam A

    更新日期:2008-03-01 00:00:00

  • Changes in stroke mortality rates for 1950 to 1997: a great slowdown of decline trend in Japan.

    abstract:BACKGROUND AND PURPOSE:Stroke is the second leading cause of death in Japan. We sought to examine changes in stroke mortality rates by age, sex, and birth cohorts from 1950 to 1997. METHODS:The numbers of deaths from stroke and the population by age and sex in subjects aged 55 to 79 years between 1950 and 1997 were ob...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.32.8.1745

    authors: Liu L,Ikeda K,Yamori Y

    更新日期:2001-08-01 00:00:00

  • Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging.

    abstract:BACKGROUND:The ability to quickly and efficiently identify the ischemic penumbra in the acute stroke clinical setting is an important goal for stroke researchers and clinicians. Early and accurate identification of potentially salvageable versus irreversibly infarcted brain tissue may enable selection of the most appro...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.STR.0000097608.38779.CC

    authors: Kidwell CS,Alger JR,Saver JL

    更新日期:2003-11-01 00:00:00

  • Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.

    abstract:BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029388

    authors: Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

    更新日期:2020-09-01 00:00:00

  • Mechanisms of perioperative cerebral infarction.

    abstract::Perioperative cerebral infarction occurs in less than 1% of general surgical procedures; the mechanism is usually unknown. The clinical features of 12 consecutive perioperative strokes were retrospectively reviewed. Although intraoperative hypotension was frequent, onset of deficit occurred postoperatively in 83% and ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.13.6.766

    authors: Hart R,Hindman B

    更新日期:1982-11-01 00:00:00

  • Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats.

    abstract:BACKGROUND AND PURPOSE:We tested the hypothesis that intravenous administration of basic fibroblast growth factor (bFGF) during 4 hours of permanent focal ischemia would affect acute brain injury. METHODS:Halothane-anesthetized cats underwent left middle cerebral artery (MCA) occlusion for 4 hours. Control cats receiv...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.3.609

    authors: Bethel A,Kirsch JR,Koehler RC,Finklestein SP,Traystman RJ

    更新日期:1997-03-01 00:00:00

  • A critical appraisal of stroke evaluation and rating scales.

    abstract:BACKGROUND:To judge the efficacy of new, putative stroke therapies, we need a method to measure neurological deficit accurately in groups of patients before and after treatment. No single measurement technique has yet proven to be universally acceptable, but one approach is the use of rating instruments that summarize ...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.22.11.1345

    authors: Lyden PD,Lau GT

    更新日期:1991-11-01 00:00:00

  • The incidence of cerebral venous thrombosis: a cross-sectional study.

    abstract:BACKGROUND AND PURPOSE:The purpose of this study was to determine the incidence of adult cerebral venous thrombosis. METHODS:A retrospective cross-sectional study was conducted among all 19 hospitals located in 2 Dutch provinces serving 3.1 million people. Adult cerebral venous thrombosis cases diagnosed between Janua...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.671453

    authors: Coutinho JM,Zuurbier SM,Aramideh M,Stam J

    更新日期:2012-12-01 00:00:00

  • Effects of reduced regional or body temperatures on responses of pial arterioles.

    abstract::We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.9.6.580

    authors: Rosenblum WI,Segreti AC

    更新日期:1978-11-01 00:00:00

  • The effect of ritanserin, a 5-HT2 receptor antagonist, on ischemic cerebral blood flow and infarct volume in rat middle cerebral artery occlusion.

    abstract:BACKGROUND AND PURPOSE:In a previous study from our laboratory, ritanserin, a specific 5-HT2 serotonin receptor antagonist, reduced ischemic damage in the setting of transient global ischemia. In this study, we examined the effect of ritanserin on ischemic cerebral blood flow, systemic blood pressure, and infarct volum...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.2.481

    authors: Takagi K,Ginsberg MD,Globus MY,Busto R,Dietrich WD

    更新日期:1994-02-01 00:00:00

  • Effect of triamcinolone acetonide injections on hemiplegic shoulder pain : A randomized clinical trial.

    abstract:UNLABELLED:Background and Purpose-Hemiplegic shoulder pain is not uncommon after stroke. Its origin is still unknown, and although many different methods of treatment are applied, none have yet been proved to be effective. We sought to study the efficacy of 3 injections of intra-articular triamcinolone acetonide on pai...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1161/01.str.31.10.2396

    authors: Snels IA,Beckerman H,Twisk JW,Dekker JH,Peter De Koning,Koppe PA,Lankhorst GJ,Bouter LM

    更新日期:2000-10-01 00:00:00

  • Effect of thrombin inhibition in vascular dementia and silent cerebrovascular disease. An MR spectroscopy study.

    abstract:BACKGROUND AND PURPOSE:Silent cerebrovascular disease (CVD) has been proposed as a predisposing condition for clinically overt stroke and vascular dementia. Recently, we found increased thrombin generation in silent CVD patients. Here, we report the effect of thrombin inhibition using a potent selective thrombin inhibi...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.str.30.5.1033

    authors: Kario K,Matsuo T,Hoshide S,Umeda Y,Shimada K

    更新日期:1999-05-01 00:00:00

  • Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury.

    abstract:BACKGROUND AND PURPOSE:The physiological function of cellular prion protein (PrPc) is not yet understood. Recent findings suggest that PrPc may have neuroprotective properties, and its absence increases susceptibility to neuronal injury. The purpose of this study was to elucidate the role of PrPc in ischemic brain inju...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000217262.03192.d4

    authors: Weise J,Sandau R,Schwarting S,Crome O,Wrede A,Schulz-Schaeffer W,Zerr I,Bähr M

    更新日期:2006-05-01 00:00:00

  • Siponimod (BAF-312) Attenuates Perihemorrhagic Edema And Improves Survival in Experimental Intracerebral Hemorrhage.

    abstract::Background and Purpose- Perihemorrhagic edema (PHE) is associated with poor outcome after intracerebral hemorrhage (ICH). Infiltration of immune cells is considered a major contributor of PHE. Recent studies suggest that immunomodulation via S1PR (sphingosine-1-phosphate receptor) modulators improve outcome in ICH. Si...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.027134

    authors: Bobinger T,Manaenko A,Burkardt P,Beuscher V,Sprügel MI,Roeder SS,Bäuerle T,Seyler L,Nagel AM,Linker RA,Engelhorn T,Dörfler A,Horsten SV,Schwab S,Huttner HB

    更新日期:2019-11-01 00:00:00

  • Body mass index and stroke risk among patients with type 2 diabetes mellitus.

    abstract:BACKGROUND AND PURPOSE:Previous studies have evaluated the association of body mass index (BMI) with the risk of all-cause and cardiovascular disease mortality among diabetic patients, and results were controversial. No studies have focused on the association between BMI and stroke risk among diabetic patients. We aime...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.006718

    authors: Li W,Katzmarzyk PT,Horswell R,Zhang Y,Zhao W,Wang Y,Johnson J,Hu G

    更新日期:2015-01-01 00:00:00

  • Fish consumption and the risk of stroke: a dose-response meta-analysis.

    abstract:BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.111.630319

    authors: Larsson SC,Orsini N

    更新日期:2011-12-01 00:00:00

  • Experimental regional cerebral ischemia in the middle cerebral artery territory in primates. Part 3: effects on brain water and electrolytes in the late phase of acute MCA stroke.

    abstract::Experimental regional cerebral ischemia was produced in the middle cerebral artery (MCA) territory in primates (M. mulatta) by macrosphere embolization. Determinations of percentage tissue dry weight and tissue sodium and potassium concentrations were obtained in samples from the ischemic and non-ischemic hemispheres ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.9.4.387

    authors: Bremer AM,Yamada K,West CR

    更新日期:1978-07-01 00:00:00

  • Stroke Risk and Mortality in Patients With Ventricular Assist Devices.

    abstract:BACKGROUND AND PURPOSE:Ventricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these devices are associated with hemorrhagic and thrombotic complications, including stroke. We assessed the incidence, risk factors, and outcomes of ischemic and hemorrhagic stroke after VAD plac...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.014049

    authors: Parikh NS,Cool J,Karas MG,Boehme AK,Kamel H

    更新日期:2016-11-01 00:00:00

  • Combining theta burst stimulation with training after subcortical stroke.

    abstract:BACKGROUND AND PURPOSE:Repetitive transcranial magnetic stimulation of the primary motor cortex (M1) may improve outcomes after stroke. The aim of this study was to determine the effects of M1 theta burst stimulation (TBS) and standardized motor training on upper-limb function of patients with chronic stroke. METHODS:...

    journal_title:Stroke

    pub_type: 信件

    doi:10.1161/STROKEAHA.110.583278

    authors: Ackerley SJ,Stinear CM,Barber PA,Byblow WD

    更新日期:2010-07-01 00:00:00

  • Factors influencing the frequency of fluorescence transients as markers of peri-infarct depolarizations in focal cerebral ischemia.

    abstract:BACKGROUND AND PURPOSE:Peri-infarct depolarizations (PIDs) that occur in ischemic boundary zones of the cerebral cortex of experimental animals have been shown to promote rather than simply to indicate the evolution of the lesion and are especially prominent in the rat. To study the influence of one factor, species, on...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.31.1.214

    authors: Strong AJ,Smith SE,Whittington DJ,Meldrum BS,Parsons AA,Krupinski J,Hunter AJ,Patel S,Robertson C

    更新日期:2000-01-01 00:00:00

  • The ferret as an animal model in cerebrovascular research.

    abstract::Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.8.1085

    authors: Atkinson CS,Press GA,Lyden P,Katz B

    更新日期:1989-08-01 00:00:00

  • Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o

    abstract:BACKGROUND AND PURPOSE:Epidemiological and laboratory studies suggest that increasing concentrations of plasma homocysteine (total homocysteine [tHcy]) accelerate cardiovascular disease by promoting vascular inflammation, endothelial dysfunction, and hypercoagulability. METHODS:We conducted a randomized controlled tri...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1161/01.STR.0000150494.91762.70

    authors: Dusitanond P,Eikelboom JW,Hankey GJ,Thom J,Gilmore G,Loh K,Yi Q,Klijn CJ,Langton P,van Bockxmeer FM,Baker R,Jamrozik K

    更新日期:2005-01-01 00:00:00