Ischemic brain damage is not ameliorated by 1,3-butanediol in hyperglycemic rats.

abstract：:Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...

journal_title：Stroke

authors： Joseph R,Welch KM,D'Andrea G

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Unstable atherosclerotic plaques are characterized by increased macrophages and reduced smooth muscle cells (SMCs) and collagen content. Endoglin, an accessory transforming growth factor-beta (TGFbeta) receptor, is a modulator of TGFbeta signaling recently found to be expressed on SMCs in atheros...

journal_title：Stroke

authors： Bot PT,Hoefer IE,Sluijter JP,van Vliet P,Smits AM,Lebrin F,Moll F,de Vries JP,Doevendans P,Piek JJ,Pasterkamp G,Goumans MJ

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acetazolamide is commonly used with single-photon CT to assess the cerebrovascular reserve in patients with internal carotid artery stenosis or occlusion. In this study we wanted to evaluate the effects of adenosine, a well-known vasodilatatory compound with a short biological half-life, on brain...

journal_title：Stroke

authors： Soricelli A,Postiglione A,Cuocolo A,De Chiara S,Ruocco A,Brunetti A,Salvatore M,Ell PJ

更新日期：1995-09-01 00:00:00

abstract：UNLABELLED:Background and Purpose-Hemiplegic shoulder pain is not uncommon after stroke. Its origin is still unknown, and although many different methods of treatment are applied, none have yet been proved to be effective. We sought to study the efficacy of 3 injections of intra-articular triamcinolone acetonide on pai...

journal_title：Stroke

authors： Snels IA,Beckerman H,Twisk JW,Dekker JH,Peter De Koning,Koppe PA,Lankhorst GJ,Bouter LM

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neonatal encephalopathy in human babies is a serious condition associated with permanent neurological deficits. Diffusion-weighted MRI (DWI) is increasingly used for early diagnosis of brain injury in human babies. The relationship between the presence of DWI abnormalities and cellular injury, in...

journal_title：Stroke

authors： Wendland MF,Faustino J,West T,Manabat C,Holtzman DM,Vexler ZS

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravascular bridges, resulting from developmental anomalies of brain arteries, are now better known as arterial fenestrations. Their tendency to develop aneurysms, similar to arterial bifurcations, makes their anatomy and microstructure important for study. METHODS:Six segments of artery, each...

journal_title：Stroke

authors： Finlay HM,Canham PB

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental and clinical data suggest that insonation of echo-contrast agents with high acoustical power produces disintegration of microbubbles, resulting in a pseudo-Doppler phenomenon called stimulated acoustic emission (SAE). The purpose of this study was to investigate whether SAE might be ...

journal_title：Stroke

authors： Pohl C,Tiemann K,Schlosser T,Becher H

更新日期：2000-07-01 00:00:00

abstract：:To determine the incidence of perioperative silent cerebral infarction, 97 patients who underwent carotid endarterectomy were prospectively studied with preoperative and postoperative computed tomograms. Thirty-one of 96 patients (32%) had findings of cerebral infarction on preoperative computed tomograms. Silent cere...

journal_title：Stroke

authors： Sise MJ,Sedwitz MM,Rowley WR,Shackford SR

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...

journal_title：Stroke

authors： Nighoghossian N,Hermier M,Adeleine P,Derex L,Dugor JF,Philippeau F,Ylmaz H,Honnorat J,Dardel P,Berthezène Y,Froment JC,Trouillas P

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies have evaluated the association of body mass index (BMI) with the risk of all-cause and cardiovascular disease mortality among diabetic patients, and results were controversial. No studies have focused on the association between BMI and stroke risk among diabetic patients. We aime...

journal_title：Stroke

authors： Li W,Katzmarzyk PT,Horswell R,Zhang Y,Zhao W,Wang Y,Johnson J,Hu G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this amino acid has been shown to be due to nutritional status and methylenetetrahydrofolate reductase (MTHFR) genotype. METHODS:Under a case-cont...

journal_title：Stroke

authors： McIlroy SP,Dynan KB,Lawson JT,Patterson CC,Passmore AP

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To clarify diagnostic entities in ischemic stroke we analyzed the relation between the severity of carotid atherosclerosis, coagulation parameters, lipoproteins, neurological status, and risk factors in 232 patients. METHODS:Duplex ultrasonography, computed tomography scan, and laboratory invest...

journal_title：Stroke

authors： Szirmai IG,Kamondi A,Magyar H,Juhász C

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Angiographic vasospasm frequently complicates subarachnoid hemorrhage and has been implicated in the development of delayed cerebral ischemia. Whether large-vessel narrowing adequately accounts for the critical reductions in regional cerebral blood flow underlying ischemia is unclear. We sought t...

journal_title：Stroke

authors： Dhar R,Scalfani MT,Blackburn S,Zazulia AR,Videen T,Diringer M

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Understanding on distinct subsets of endothelial progenitor cells may provide insights of endothelial dysfunction or repair in the acute ischemic event. Recent in vitro data have reported the colony-forming unit (CFU) and outgrowth cell population as a subset of endothelial progenitor cells. In t...

journal_title：Stroke

authors： Chu K,Jung KH,Lee ST,Park HK,Sinn DI,Kim JM,Kim DH,Kim JH,Kim SJ,Song EC,Kim M,Lee SK,Roh JK

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal studies have shown that MR diffusion imaging can outline acute ischemic regions before irreversible damage (infarction) occurs. To study evolution of ischemic lesions in humans, it is therefore important to quantify absolute diffusion constants (D values), but quantitation has not been rep...

journal_title：Stroke

authors： Uluğ AM,Beauchamp N Jr,Bryan RN,van Zijl PC

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With the exception of atrial fibrillation (AF), little scientific attention has been given the associations between cardiac arrhythmias and incidence of stroke. We sought to study whether atrial and ventricular arrhythmias assessed during a 24-hour ambulatory ECG registration are associated with ...

journal_title：Stroke

authors： Engström G,Hedblad B,Juul-Möller S,Tydén P,Janzon L

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A supraphysiological amount of vitamin E in the standard diet of laboratory animals may provide partial protection against cerebral ischemic damage in stroke models. The aim of the present study was to test the effect of dietary vitamin E on infarct volume in rats subjected to permanent focal cer...

journal_title：Stroke

authors： van der Worp HB,Bär PR,Kappelle LJ,de Wildt DJ

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to assess outcomes after endovascular treatment/therapy of acute ischemic stroke, overall and by subgroups, and looked for predictors of outcome. METHODS:We used data from a mandatory, population-based registry that includes external monitoring of completeness, which assesses reperfusi...

journal_title：Stroke

authors： Abilleira S,Cardona P,Ribó M,Millán M,Obach V,Roquer J,Cánovas D,Martí-Fàbregas J,Rubio F,Alvarez-Sabín J,Dávalos A,Chamorro A,de Miquel MA,Tomasello A,Castaño C,Macho JM,Ribera A,Gallofré M,Catalan Stroke Code and Re

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic ocular ischemia is a rare form of ischemia of the eye in patients with carotid artery occlusion (CAO). The early and often asymptomatic stage of chronic ocular ischemia is referred to as venous stasis retinopathy (VSR). The aim of this study was to gain insight into the prevalence, cause,...

journal_title：Stroke

authors： Klijn CJ,Kappelle LJ,van Schooneveld MJ,Hoppenreijs VP,Algra A,Tulleken CA,van Gijn J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Nimodipine, a calcium antagonist, has been reported to have beneficial effects in acute ischemic infarction. Some calcium channel antagonists have antiplatelet effects. We investigated the effect of oral nimodipine on platelet function in healthy volunteers. METHODS:Twelve healthy volunteers (6 ...

journal_title：Stroke

authors： Feinberg WM,Bruck DC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery of upper-limb motor impairment after first-ever ischemic stroke is proportional to the degree of initial impairment in patients with a functional corticospinal tract (CST). This study aimed to investigate whether proportional recovery occurs in a more clinically relevant sample including...

journal_title：Stroke

authors： Stinear CM,Byblow WD,Ackerley SJ,Smith MC,Borges VM,Barber PA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conventional diets may cause hyperglycemia in patients with neurological injuries. The purpose of this study was to examine the effect on the severity of cerebral infarction of replacing carbohydrates as the primary dietary source of nonprotein calories. METHODS:Sixty-nine Long-Evans rats were e...

journal_title：Stroke

authors： Robertson C,Goodman JC,Grossman RG,Claypool M,White A

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The natural history of stroke is still incompletely understood. The aim of this study was to present detailed data on survival, recurrence, and all types of healthcare utilization before and after a stroke event in patients with stroke. METHODS:Three hundred ninety stroke survivors constituted t...

journal_title：Stroke

authors： Olai L,Omne-Pontén M,Borgquist L,Svärdsudd K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anemia is 1 potential mechanism by which the brain receives inadequate oxygenation. The purpose of this study was to determine in acute stroke patients whether lower hemoglobin values were associated with worse hemispatial neglect. METHODS:In 203 subjects, neglect testing batteries were administ...

journal_title：Stroke

authors： Gottesman RF,Bahrainwala Z,Wityk RJ,Hillis AE

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of statins on progression of carotid intima-media complex thickness (IMT) has been shown exclusively in nonstroke Western patients. This study aimed to determine the effect of low-dose pravastatin on carotid IMT in Japanese patients with noncardioembolic ischemic stroke. METHODS:This ...

journal_title：Stroke

authors： Koga M,Toyoda K,Minematsu K,Yasaka M,Nagai Y,Aoki S,Nezu T,Hosomi N,Kagimura T,Origasa H,Kamiyama K,Suzuki R,Ohtsuki T,Maruyama H,Kitagawa K,Uchiyama S,Matsumoto M,J-STARS Investigators.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. METHODS:Ten Catholic churches were randomize...

journal_title：Stroke

authors： Brown DL,Conley KM,Sánchez BN,Resnicow K,Cowdery JE,Sais E,Murphy J,Skolarus LE,Lisabeth LD,Morgenstern LB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While brain tissue lactate increases during cerebral ischemia and is known to be important in the pathogenesis of ischemic brain injury, patterns of extracellular lactate accumulation have been less well characterized, and the influence of brain temperature has not been previously investigated. M...

journal_title：Stroke

authors： Lin B,Busto R,Globus MY,Martinez E,Ginsberg MD

更新日期：1995-09-01 00:00:00

abstract：:We examined cerebral lipid peroxidation, estimated by a thiobarbituric acid test, in rat brain regions after 30 minutes of severe forebrain ischemia and at recirculation periods of up to 72 hours. The lipid peroxide levels remained unaltered in all brain regions during ischemia and during the first hour of recirculati...

journal_title：Stroke

authors： Bromont C,Marie C,Bralet J

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of the study was to determine the effects of thromboembolism and mechanical thrombectomy on the vessel wall magnetic resonance imaging (VW-MRI) appearance of the intracranial arterial wall. METHODS:This was a cross-sectional study of consecutive patients with acute intracranial arterial ...

journal_title：Stroke

authors： Power S,Matouk C,Casaubon LK,Silver FL,Krings T,Mikulis DJ,Mandell DM

更新日期：2014-08-01 00:00:00