Abstract:
BACKGROUND AND PURPOSE:Anemia is 1 potential mechanism by which the brain receives inadequate oxygenation. The purpose of this study was to determine in acute stroke patients whether lower hemoglobin values were associated with worse hemispatial neglect. METHODS:In 203 subjects, neglect testing batteries were administered within 24 hours of admission for acute right hemispheric stroke. We analyzed the error rate on each test as well as "any neglect" (z score >or=2 on any of 3 selected tests compared with normal controls), as predicted by hemoglobin level, with adjustment for infarct size, National Institutes of Health Stroke Scale score, age, and sex. RESULTS:The association between hemoglobin and neglect varied on the basis of hemoglobin level. At lower hemoglobin levels (<12 g/dL), each 1-point higher hemoglobin value was protective (adjusted odds ratio=0.56; 95% CI, 0.35 to 0.89) from having "any neglect." However, for a hemoglobin value >14 g/dL, each 1-point higher hemoglobin value was associated with higher odds of having neglect (adjusted odds ratio=1.67; 95% CI, 1.09 to 2.57). Similar relations were found for predicted error rate on the horizontal line bisection, line cancellation, and copy Ogden scene neglect tests. These relations seemed to be more pronounced in individuals who had a diffusion/perfusion mismatch. CONCLUSIONS:Lower and higher hemoglobin levels were each associated with increased odds of neglect and with worse severity of neglect, independent of stroke size and severity. Higher hemoglobin values may represent dehydration or hyperviscosity. The importance of the extremes of hemoglobin in identifying individuals at risk for worse functional consequences of stroke warrants further study.
journal_name
Strokejournal_title
Strokeauthors
Gottesman RF,Bahrainwala Z,Wityk RJ,Hillis AEdoi
10.1161/STROKEAHA.110.585265subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1641-5issue
8eissn
0039-2499issn
1524-4628pii
STROKEAHA.110.585265journal_volume
41pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Discharge ICD-9-CM (International Classification of Diseases, 9th Revision, Clinical Modification) codes have been used to identify patients with acute stroke for epidemiological, quality of care, and cost studies. The aim of this study was to determine if the accuracy of the primary ICD-9-CM cod...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.8.1602
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke has been shown to alter autonomic function. The purpose of this study was to show the differential effects of stroke localization on autonomic function parameters assessed by heart rate variability (HRV). METHODS:To determine the differential effect of ischemic stroke localization on auto...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.7.1307
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The reliability of the National Institutes of Health Stroke Scale (NIHSS) has been established through testing its use in live and videotaped patients. This reliability testing has primarily focused on the use of the scale by neurologists. We sought to determine the reliability of the NIHSS as us...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.2.307
更新日期:1997-02-01 00:00:00
abstract::Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.023445
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ipsilateral thalamic diaschisis (ITD) describes the reduction of thalamic function, metabolism, and perfusion resulting from a distant lesion of the ipsilateral hemisphere. Our aim was to evaluate the perfusion characteristics and clinical impact of ITD in acute middle cerebral artery stroke, whi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.020698
更新日期:2018-04-01 00:00:00
abstract::MRI is becoming the imaging modality of choice in patients with ischemic cerebrovascular disease although CT is still the test of choice to exclude acute hemorrhagic stroke. We have briefly reviewed characteristic features of ischemic and hemorrhagic cerebrovascular disease as well as vascular anomalies as seen on MRI...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.20.9.1279
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We analyzed the impact of detailed anatomic characteristics on the results of endovascular coil embolization for anterior communicating artery (AcoA) aneurysms and developed a predictive model estimating the probability of successful endovascular treatment. METHODS:One hundred eighty-one AcoA an...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.505222
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS:In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke sur...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000121643.86762.9a
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Endovascular treatment can improve the outcome of patients treated for ruptured intracranial aneurysms as compared with surgical clipping, but angiographic recurrences are frequent. Endothelial denudation before coil embolization may prevent recanalization and improve results of endovascular trea...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000126042.76153.f7
更新日期:2004-06-01 00:00:00
abstract::Though unilateral blood distribution of the vertebral artery has not been studied in humans, it is significant when considering the ischemic events especially embolic occlusion in vertebrobasilar system. To clarify the blood distribution, Krypton-81m was continuously infused into the vertebral arteries of 10 patients....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.15.3.469
更新日期:1984-05-01 00:00:00
abstract::Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.8.1085
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Administration of histamine receptor antagonists has been reported to produce contradictory results, either reducing or increasing neural damage induced by ischemia. In this study, we investigated the neuroprotective effects of histamine H2-receptor antagonists in an "in vitro" model of ischemia....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000141160.66818.24
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The watershed cortical areas are the first to be deprived of sufficient blood flow in the event of cerebral hypoperfusion and will be the sites of watershed microinfarcts. Cerebral hypoperfusion is associated with Alzheimer disease (AD), but information regarding the occurrence of watershed corti...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000024523.82311.77
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic microangiopathy with prevalently cerebral manifestations. Among the causes of death, sudden unexpected death seems to occur in a significant number of CADASIL patients. Be...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000254530.38417.07
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Symptomatic intracranial hemorrhage (SICH) is the most feared complication after tissue plasminogen activator (tPA) stroke treatment. Endogenous fibrinolysis inhibitors play an essential role in the coagulation/fibrinolysis balance and may be involved in the bleeding process. We aim to determine ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000137608.73660.4c
更新日期:2004-09-01 00:00:00
abstract::Background and Purpose- The CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) demonstrated equivalent composite outcomes between carotid endarterectomy (CEA) and carotid artery stenting (CAS) for treating carotid stenosis. We investigated nationwide trends in these procedures and associated peripr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027388
更新日期:2020-02-01 00:00:00
abstract::Among 21 patients with angiographically demonstrated stenosis of the middle cerebral artery (MCA) 14 presented with a stroke and 7 with transient ischaemic attacks (TIAs). Of the former 4 had further strokes (3 fatal); of the latter one had a fatal stroke. Only 2 of the 21 patients had TIAs during the follow-up period...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.15.2.237
更新日期:1984-03-01 00:00:00
abstract:BACKGROUND:A number of clinical syndromes describing the presentation of deep brain infarcts are called lacunar syndromes resulting from small vessel occlusion (SVO). To verify the reliability of the clinical diagnosis "lacunar syndrome," the value was investigated with diffusion-weighted MRI (DWI). METHODS AND RESULT...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000158908.48022.d7
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is the second leading cause of death in Japan. We sought to examine changes in stroke mortality rates by age, sex, and birth cohorts from 1950 to 1997. METHODS:The numbers of deaths from stroke and the population by age and sex in subjects aged 55 to 79 years between 1950 and 1997 were ob...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.8.1745
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To study the longitudinal relationship of functional change in walking ability and change in time-dependent covariates and to develop a multivariate regression model to predict longitudinal change of walking ability. METHODS:A total of 101 acute stroke patients with first-ever ischemic middle ce...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/01.STR.0000190839.29234.50
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The combination of low-dose aspirin and dipyridamole is more effective than aspirin alone in reducing the risk of recurrent stroke and other major cardiovascular events in patients with a recent transient ischemic attack or minor stroke. It is unknown whether this also applies to patients with a ...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.110.586453
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Space-occupying brain edema is a life-threatening complication in patients with large middle cerebral artery (MCA) infarction. To determine predictors of this detrimental process, we investigated alterations of extracellular non-transmitter amino acid concentrations in peri-infarct tissue. METHO...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.STR.0000100158.51986.EB
更新日期:2003-12-01 00:00:00
abstract::Background and Purpose- Cerebral small vessel disease (SVD) is a major cause of stroke and dementia, but underlying disease mechanisms are still largely unknown, partly because of the difficulty in assessing small vessel function in vivo. We developed a method to measure blood flow velocity pulsatility in perforating ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022516
更新日期:2018-12-11 00:00:00
abstract:BACKGROUND AND PURPOSE:Multiple acute ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI-MRI) are thought to be of embolic origin. However, in several patients with multiple ischemic lesions on DWI-MRI, no embolic source was detected, despite a thorough clinical work-up. Stroke etiology in such case...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000231645.22128.ab
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The newly-described computed tomography angiography (CTA) Spot Sign is present in about one third of patients with acute primary intracerebral hemorrhage (PICH) and predicts hematoma expansion. This sign has not been systematically evaluated in patients with secondary causes of ICH, and mimics ha...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.499442
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to investigate the direct costs of acute hospitalization for patients with first-ever ischemic stroke in Taiwan. METHODS:Data were prospectively collected from 360 first-ever ischemic stroke patients. Hospital charges were used for analysis. Multiple linear regression analysis was used...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000095565.12945.18
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/01.STR.0000181754.38408.4c
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Brain injury caused by stroke is a frequent cause of perinatal morbidity and mortality with limited therapeutic options. Mesenchymal stem cells (MSC) have been shown to improve outcome after neonatal hypoxic-ischemic brain injury mainly by secretion of growth factors stimulating repair processes....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000326
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.542308
更新日期:2009-08-01 00:00:00
abstract::The presence of hyperglycemia prior to stroke or cardiac arrest can increase neuronal damage caused by brain ischemia. Acute hyperglycemia shows this effect in animal models of stroke. However, chronic hyperglycemia and chronic hyperglycemia with additional acute elevation of blood glucose are more common premorbid st...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.52
更新日期:1987-01-01 00:00:00