Histamine H2-receptor antagonist ranitidine protects against neural death induced by oxygen-glucose deprivation.

abstract：:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregive...

journal_title：Stroke

authors： Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aim to evaluate if good collateral flow (CF) modifies endovascular therapy (EVT) efficacy on large-vessel stroke. To do that, we used final degree of reperfusion and number of device-passes performed, factors previously associated with better functional outcome, as main outcome measures. METH...

journal_title：Stroke

authors： García-Tornel Á,Ciolli L,Rubiera M,Requena M,Muchada M,Pagola J,Rodriguez-Luna D,Deck M,Juega J,Rodríguez-Villatoro N,Boned S,Olivé-Gadea M,Sanjuan E,Tomasello A,Piñana C,Hernández D,Álvarez-Sabin J,Molina CA,Ribó M

更新日期：2021-01-01 00:00:00

abstract：:The trends in age adjusted and age and sex specific mortality rates for the period 1968-1980 are compared for ischaemic heart disease and cerebrovascular disease. For both sexes and at all ages over 45 the mortality rates for cerebrovascular disease have fallen significantly. However, the mortality rates for ischaemic...

journal_title：Stroke

authors： Haberman S,Capildeo R,Rose FC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined the possibility that activation of the human brain renin-angiotensin system is involved in enhancement of ischemic brain damage using chimeric transgenic mice with human renin (hRN) and human angiotensinogen (hANG) genes. METHODS:Chimeric (hRN/hANG-Tg) mice were generated by mating o...

journal_title：Stroke

authors： Inaba S,Iwai M,Tomono Y,Senba I,Furuno M,Kanno H,Okayama H,Mogi M,Higaki J,Horiuchi M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been suggested that the interleukin-1A (IL-1A) allele 2 is a risk factor for Alzheimer's disease (AD). Because cerebral amyloid angiopathy-related hemorrhage (CAAH) often coexists with AD, we examined the IL-1A polymorphism in CAAH. METHODS:In a case-control study, patients with pathologi...

journal_title：Stroke

authors： McCarron MO,Stewart J,McCarron P,Love S,Vinters HV,Ironside JW,Mann DM,Graham DI,Nicoll JA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Earlier tissue-type plasminogen activator (tPA) treatment for acute ischemic stroke increases efficacy, prompting national efforts to reduce door-to-needle times. We used lean process improvement methodology to develop a streamlined intravenous tPA protocol. METHODS:In early 2011, a multidiscipl...

journal_title：Stroke

authors： Ford AL,Williams JA,Spencer M,McCammon C,Khoury N,Sampson TR,Panagos P,Lee JM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein. METHODS:A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary p...

journal_title：Stroke

authors： Ozawa M,Yoshida D,Hata J,Ohara T,Mukai N,Shibata M,Uchida K,Nagata M,Kitazono T,Kiyohara Y,Ninomiya T

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inflammation is thought to be a major contributor to carotid artery disease. Lipopolysaccharide (LPS) activates inflammatory mechanisms thought to contribute to endothelial dysfunction by mechanisms that are not well defined. The goal of this study was to determine whether overexpression of CuZn-...

journal_title：Stroke

authors： Didion SP,Kinzenbaw DA,Fegan PE,Didion LA,Faraci FM

更新日期：2004-08-01 00:00:00

abstract：:In a case-control study of 73 cases of cerebral hematoma diagnosed by CT scan, significant risk factors were history of hypertension, chronic alcoholism, evidence of hepatic disease, EKG abnormalities and high hematocrit values. Initial blood pressure was significantly higher in cases, but blood pressure on the third ...

journal_title：Stroke

authors： Calandre L,Arnal C,Ortega JF,Bermejo F,Felgeroso B,del Ser T,Vallejo A

更新日期：1986-11-01 00:00:00

abstract：:I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...

journal_title：Stroke

authors： Ryding E

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been postulated that physiological changes in the cardiovascular system, lipids, and glucose metabolism during pregnancy may increase subsequent risk of cardiovascular disease. Examination of the association between parity and risk factors for atherosclerosis may contribute information reg...

journal_title：Stroke

authors： Humphries KH,Westendorp IC,Bots ML,Spinelli JJ,Carere RG,Hofman A,Witteman JC

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the mechanisms that contribute to intracranial aneurysm (IA) formation and rupture are not totally elucidated, inflammation and matrix remodeling are incriminated. Because tPA (tissue-type plasminogen activator) controls both inflammatory and matrix remodeling processes, we hypothesized ...

journal_title：Stroke

authors： Labeyrie PE,Goulay R,Martinez de Lizarrondo S,Hébert M,Gauberti M,Maubert E,Delaunay B,Gory B,Signorelli F,Turjman F,Touzé E,Courthéoux P,Vivien D,Orset C

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to further analyze the temporal patterns of onset of intracerebral hemorrhage (ICH) and to determine whether or not subgroups with specific clinical characteristics exhibit different patterns of onset. METHODS:The daily, weekly, and yearly variations in occurrence o...

journal_title：Stroke

authors： Passero S,Reale F,Ciacci G,Zei E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to clarify the pathophysiology of perioperative cerebral complications during carotid endarterectomy in our series. METHODS:By means of transcranial Doppler ultrasonography and stump pressure measurement, we monitored 112 patients who underwent carotid endarterectomy und...

journal_title：Stroke

authors： Finocchi C,Gandolfo C,Carissimi T,Del Sette M,Bertoglio C

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Higher plasma total homocysteine (tHcy) levels have been associated with carotid atherosclerosis and cerebral infarction in whites. However, data regarding such associations are limited for Asians. This study examined associations between tHcy levels and severity of carotid atherosclerosis in Jap...

journal_title：Stroke

authors： Sasaki T,Watanabe M,Nagai Y,Hoshi T,Takasawa M,Nukata M,Taguchi A,Kitagawa K,Kinoshita N,Matsumoto M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Three-dimensional pseudocontinuous arterial spin labeling with multiple postlabeling delays has been used to assess cerebral blood flow (CBF). We used this modality to estimate antegrade and collateral flow in patients with unilateral middle cerebral artery stenosis. METHODS:Consecutive patients...

journal_title：Stroke

authors： Lyu J,Ma N,Liebeskind DS,Wang DJ,Ma L,Xu Y,Wang T,Miao Z,Lou X

更新日期：2016-02-01 00:00:00

abstract：:Background and Purpose- Absent or diminished α-galactosidase A (GLA) and acid α-glucosidase (GAA) enzyme activity are core features of Fabry and Pompe disease, respectively. Patients with Fabry or Pompe disease may have dilated intracranial arteries but whether lower GLA or GAA enzyme activity relates to brain arteria...

journal_title：Stroke

authors： Shah H,Liong C,Levy OA,Waters C,Fahn S,Marder K,Kang UJ,Wolf P,Oliva P,Zhang K,Alcalay RN,Gutierrez J

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The sensitivity of the brain to brief periods of profound ischemia or prolonged periods of modest ischemia mandates an aggressive approach to acute stroke care. Past studies have shown that many stroke patients do not receive acute care in an urgent and timely fashion. The formation of acute stro...

journal_title：Stroke

authors： Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke MRI protocols provide useful information about underlying vessel pathologies in the anterior circulation by means of intracranial time-of-flight angiography. However, these protocols mostly fail in the posterior circulation to differentiate between congenital variants and secondary thrombo...

journal_title：Stroke

authors： Freund W,Kassubek J,Aschoff AJ,Huber R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Potassium intake has been inconsistently associated with risk of stroke. Our aim was to conduct a meta-analysis of prospective studies to assess the relation between potassium intake and stroke risk. METHODS:Pertinent studies were identified by a search of PubMed from January 1966 through March ...

journal_title：Stroke

authors： Larsson SC,Orsini N,Wolk A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Indications for carotid endarterectomy have engendered considerable debate among experts and have resulted in publication of retrospective reviews, natural history studies, audits of community practice, position papers, expert opinion statements, and finally prospective randomized trials. The Ame...

journal_title：Stroke

authors： Moore WS,Barnett HJ,Beebe HG,Bernstein EF,Brener BJ,Brott T,Caplan LR,Day A,Goldstone J,Hobson RW 2nd

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences. M...

journal_title：Stroke

authors： Yaghi S,Moon YP,Mora-McLaughlin C,Willey JZ,Cheung K,Di Tullio MR,Homma S,Kamel H,Sacco RL,Elkind MS

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prophylactic administration of simvastatin has been shown to protect against brain damage and its long-lasting behavioral consequences in neonatal rats. To establish the drug treatment window, we evaluated the effectiveness of simvastatin administered at different intervals before and after strok...

journal_title：Stroke

authors： Balduini W,Mazzoni E,Carloni S,De Simoni MG,Perego C,Sironi L,Cimino M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

journal_title：Stroke

authors： Johnson SH,Kraimer JM,Graeber GM

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent studies have shown that the cerebral arteriolar dilation from hypercapnic acidosis is blocked by agents which inhibit KATP channels. These findings suggested that this response is due to opening of KATP channels. Because the repose to CO2 is a continuum, with hypercapnic acidosis causing v...

journal_title：Stroke

authors： Wei EP,Kontos HA

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Angiographic vasospasm frequently complicates subarachnoid hemorrhage and has been implicated in the development of delayed cerebral ischemia. Whether large-vessel narrowing adequately accounts for the critical reductions in regional cerebral blood flow underlying ischemia is unclear. We sought t...

journal_title：Stroke

authors： Dhar R,Scalfani MT,Blackburn S,Zazulia AR,Videen T,Diringer M

更新日期：2012-07-01 00:00:00

abstract：:A woman who presented with a subarachnoid hemorrhage secondary to a ruptured anterior spinal artery aneurysm of the spinal cord is reported. While this is the first report of a ruptured aneurysm of the anterior spinal artery with angiographic confirmation, it emphasizes that occasionally subarachnoid hemorrhage may be...

journal_title：Stroke

authors： Vincent FM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ventricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these devices are associated with hemorrhagic and thrombotic complications, including stroke. We assessed the incidence, risk factors, and outcomes of ischemic and hemorrhagic stroke after VAD plac...

journal_title：Stroke

authors： Parikh NS,Cool J,Karas MG,Boehme AK,Kamel H

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Development of translational functional imaging modalities for atherosclerosis risk stratification is sought for stroke prediction. Our group has developed late-phase contrast-enhanced ultrasound (LP-CEUS) to quantify microbubble contrast retention within carotid atherosclerosis and shown it to s...

journal_title：Stroke

authors： Shalhoub J,Monaco C,Owen DR,Gauthier T,Thapar A,Leen EL,Davies AH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...

journal_title：Stroke

authors： Anderson C,Ni Mhurchu C,Scott D,Bennett D,Jamrozik K,Hankey G,Australasian Cooperative Research on Subarachnoid Hemorrhage Study Group.

更新日期：2003-07-01 00:00:00