Role of transcranial Doppler and stump pressure during carotid endarterectomy.

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...

journal_title：Stroke

authors： Schallner N,Lieberum JL,Gallo D,LeBlanc RH 3rd,Fuller PM,Hanafy KA,Otterbein LE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral arteries develop stretch-induced myogenic tone, which plays an important role in the regulation of blood flow to the brain. Although the effect of oxidized LDL (Ox-LDL) on many aspects of the vascular endothelial and smooth muscle cell function have been extensively investigated, its inf...

journal_title：Stroke

authors： Xie H,Bevan JA

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The results of previous studies suggest that early goal-directed fluid therapy (EGDT) reduces delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage, but the effects of EGDT on clinical outcomes are still unclear. This study aimed to determine whether EGDT improves outcomes comp...

journal_title：Stroke

authors： Mutoh T,Kazumata K,Terasaka S,Taki Y,Suzuki A,Ishikawa T

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A significant number of patients with aneurysmal subarachnoid hemorrhage are active smokers and at risk for acute nicotine withdrawal. There is conflicting literature regarding the vascular effects of nicotine and theoretical concern that it may worsen vasospasm. The literature on the safety of n...

journal_title：Stroke

authors： Carandang RA,Barton B,Rordorf GA,Ogilvy CS,Sims JR

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The most powerful predictors of functional recovery and eventual home discharge among stroke survivors are the initial severity of the stroke and the patient's age. We analyzed a large population of stroke rehabilitation admissions by stratifying subgroups with coherent outcomes in an attempt to ...

journal_title：Stroke

authors： Alexander MP

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inflammatory cytokines are involved in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). This study was conducted to examine the role of p38 mitogen-activated protein kinase (MAPK) in the development of vasospasm and cytokine production. METHODS:We measured the expressi...

journal_title：Stroke

authors： Sasaki T,Kasuya H,Onda H,Sasahara A,Goto S,Hori T,Inoue I

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ABCD system was developed to predict early stroke risk after transient ischemic attack. Incorporation of brain imaging findings has been suggested, but reports have used inconsistent methods and been underpowered. We therefore performed an international, multicenter collaborative study of the...

journal_title：Stroke

authors： Giles MF,Albers GW,Amarenco P,Arsava MM,Asimos A,Ay H,Calvet D,Coutts S,Cucchiara BL,Demchuk AM,Johnston SC,Kelly PJ,Kim AS,Labreuche J,Lavallee PC,Mas JL,Merwick A,Olivot JM,Purroy F,Rosamond WD,Sciolla R,Rothw

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Space-occupying brain edema is a life-threatening complication in patients with large middle cerebral artery (MCA) infarction. To determine predictors of this detrimental process, we investigated alterations of extracellular non-transmitter amino acid concentrations in peri-infarct tissue. METHO...

journal_title：Stroke

authors： Bosche B,Dohmen C,Graf R,Neveling M,Staub F,Kracht L,Sobesky J,Lehnhardt FG,Heiss WD

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In prehension tasks with objects placed within arm's reach, patients with hemiparesis caused by stroke use excessive trunk movement to compensate for arm motor impairments. Compensatory trunk movements may improve motor function in the short term but may limit arm recovery in the long term. Previ...

journal_title：Stroke

authors： Michaelsen SM,Levin MF

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-related physical disability can diminish quality of daily living, place care burden on families, and increase need for long-term institutionalization. We developed a prognostic index for use in research and with potential for adaptation to clinical practice that establishes the likelihood ...

journal_title：Stroke

authors： Stineman MG,Maislin G,Fiedler RC,Granger CV

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of disability in the Western world; however, few therapies are at hand to decrease this burden. SUMMARY OF REVIEW:Endothelial progenitor cells (EPCs) have been introduced in cardiovascular medicine as factotums. EPCs can repair damaged endothelium and attenuate the de...

journal_title：Stroke

authors： Rouhl RP,van Oostenbrugge RJ,Damoiseaux J,Tervaert JW,Lodder J

更新日期：2008-07-01 00:00:00

abstract：:We have studied a new high-affinity competitive N-methyl-D-aspartate antagonist, D-CPP-ene (SDZ-EAA 494), in two models of focal cerebral ischemia. In the cat middle cerebral artery occlusion model (6 hours' survival), pretreatment with D-CPP-ene reduced infarct size by 64% (15 mg/kg dose) and 60% (4.5 mg/kg dose). Th...

journal_title：Stroke

authors： Bullock R,McCulloch J,Graham DI,Lowe D,Chen MH,Teasdale GM

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events. METHODS:Two hundred three community-dwelling adults (Northern Manhattan Study; age, 68 ± 11; age range, 50 to 93 ...

journal_title：Stroke

authors： Carrelli AL,Walker MD,Lowe H,McMahon DJ,Rundek T,Sacco RL,Silverberg SJ

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Osteogenic protein-1 (OP1) not only possesses trophic activity on bone tissue but also influences neuronal survival and differentiation in vitro. Specific receptors for OP1 are present in brain and spinal cord and can be upregulated during cerebral contusion. OP1 is a member of the transforming g...

journal_title：Stroke

authors： Lin SZ,Hoffer BJ,Kaplan P,Wang Y

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aims were to identify predictors of early neurological improvement in acute ischemic stroke patients, to evaluate its impact on clinical outcome, and to investigate possible mechanisms. METHODS:A consecutive series of 152 first-ever ischemic hemispheric stroke patients hospitalized within 5 ...

journal_title：Stroke

authors： Toni D,Fiorelli M,Bastianello S,Falcou A,Sette G,Ceschin V,Sacchetti ML,Argentino C

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[18F]fluoromisonidazole (FMISO) positron emission tomography has been used to image hypoxia early after human stroke. To further study the role of hypoxia in stroke and the binding characteristics of FMISO, we aimed to develop [3H]FMISO autoradiography in an animal stroke model. We hypothesized t...

journal_title：Stroke

authors： Spratt NJ,Ackerman U,Tochon-Danguy HJ,Donnan GA,Howells DW

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-dose human albumin (ALB) is robustly neuroprotective in rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of ALB therapy in ischemic stroke. We analyzed the data for preliminary evidence of treatment efficacy. METHODS:Eighty-two subjects with acute isc...

journal_title：Stroke

authors： Palesch YY,Hill MD,Ryckborst KJ,Tamariz D,Ginsberg MD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:A number of clinical syndromes describing the presentation of deep brain infarcts are called lacunar syndromes resulting from small vessel occlusion (SVO). To verify the reliability of the clinical diagnosis "lacunar syndrome," the value was investigated with diffusion-weighted MRI (DWI). METHODS AND RESULT...

journal_title：Stroke

authors： Wessels T,Röttger C,Jauss M,Kaps M,Traupe H,Stolz E

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...

journal_title：Stroke

authors： Anderson C,Ni Mhurchu C,Scott D,Bennett D,Jamrozik K,Hankey G,Australasian Cooperative Research on Subarachnoid Hemorrhage Study Group.

更新日期：2003-07-01 00:00:00

abstract：:A 39-year-old woman had an embolic upper division middle cerebral artery branch occlusion 3 hours after smoking the free base of cocaine ("crack"). Radionuclide ventriculography demonstrated cardiomyopathy, and echocardiography documented a left atrial thrombus. This case demonstrates that embolism is one mechanism of...

journal_title：Stroke

authors： Petty GW,Brust JC,Tatemichi TK,Barr ML

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Declining trends in the incidence and mortality of stroke have been observed in Finland since the beginning of the 1980s until 1997. In this study we analyzed the trends in fatal and nonfatal strokes in Finland during 1991-2002. METHODS:The Finnish Hospital Discharge Register was linked to the N...

journal_title：Stroke

authors： Pajunen P,Pääkkönen R,Hämäläinen H,Keskimäki I,Laatikainen T,Niemi M,Rintanen H,Salomaa V

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Research on the relationship between caffeine-containing medicines (CCMs) and the risk of hemorrhagic stroke (HS) is sparse. The aim of this study is to evaluate the association between CCMs and the risk of HS. METHODS:We performed a multicenter case-control study in South Korea, from 2002 to 20...

journal_title：Stroke

authors： Lee SM,Choi NK,Lee BC,Cho KH,Yoon BW,Park BJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to cl...

journal_title：Stroke

authors： Saini M,Ikram K,Hilal S,Qiu A,Venketasubramanian N,Chen C

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity. METHODS:We performed a r...

journal_title：Stroke

authors： Rostanski SK,Shahn Z,Elkind MSV,Liberman AL,Marshall RS,Stillman JI,Williams O,Willey JZ

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most randomized controlled trials of venous thromboembolism prophylaxis have focused on reduction of deep vein thrombosis, predominantly asymptomatic deep vein thrombosis, detected on imaging. We aimed to estimate the effects of graduated compression stockings on venous thromboembolism events, su...

journal_title：Stroke

authors： CLOTS Trials Collaboration.,Dennis M,Sandercock P,Reid J,Graham C,Murray G,Venables G,Rudd A,Bowler G

更新日期：2013-04-01 00:00:00

abstract：:Functional assessment of animals following experimental cerebral ischemia is often difficult due to the passive nature of many neurologic exams. We attempted to increase the objectivity of motor function evaluation by adapting quantifiable behavioral tests and actively testing rats' motor capability following a cerebr...

journal_title：Stroke

authors： Combs DJ,D'Alecy LG

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most previous studies addressed the cognitive impact of lacunar infarcts using radiologic correlations that are known to correlate poorly with neuropathological data. Moreover, absence of systematic bilateral assessment of vascular lesions and masking effects of Alzheimer disease pathology and ma...

journal_title：Stroke

authors： Gold G,Kövari E,Herrmann FR,Canuto A,Hof PR,Michel JP,Bouras C,Giannakopoulos P

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

journal_title：Stroke

authors： Johnson SH,Kraimer JM,Graeber GM

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00

abstract：:We investigated seasonal variation in the incidence of cerebral stroke among the general population aged greater than or equal to 40 years in November of 1961 in Hisayama, Japan. During the 24-year follow-up period, 311 cases of cerebrovascular diseases occurred. The date or month of onset was determined in 308 cases,...

journal_title：Stroke

authors： Shinkawa A,Ueda K,Hasuo Y,Kiyohara Y,Fujishima M

更新日期：1990-09-01 00:00:00